FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7966, 401 aa 1>>>pF1KB7966 401 - 401 aa - 401 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2856+/-0.000813; mu= 7.5518+/- 0.050 mean_var=247.6336+/-49.821, 0's: 0 Z-trim(116.6): 42 B-trim: 0 in 0/54 Lambda= 0.081502 statistics sampled from 17247 (17288) to 17247 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.531), width: 16 Scan time: 3.730 The best scores are: opt bits E(32554) CCDS11834.1 TGIF1 gene_id:7050|Hs108|chr18 ( 401) 2747 335.3 6e-92 CCDS11832.1 TGIF1 gene_id:7050|Hs108|chr18 ( 286) 1787 222.3 4.6e-58 CCDS11833.1 TGIF1 gene_id:7050|Hs108|chr18 ( 272) 1784 221.9 5.6e-58 CCDS11835.1 TGIF1 gene_id:7050|Hs108|chr18 ( 252) 1688 210.6 1.3e-54 CCDS13278.1 TGIF2 gene_id:60436|Hs108|chr20 ( 237) 533 74.7 9.8e-14 >>CCDS11834.1 TGIF1 gene_id:7050|Hs108|chr18 (401 aa) initn: 2747 init1: 2747 opt: 2747 Z-score: 1764.2 bits: 335.3 E(32554): 6e-92 Smith-Waterman score: 2747; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401) 10 20 30 40 50 60 pF1KB7 MVLAQSRVSAGVGSPHCSGSGGGGSDSFPWPASHPGNPQCSFSTAFLASPRLSRGTLAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MVLAQSRVSAGVGSPHCSGSGGGGSDSFPWPASHPGNPQCSFSTAFLASPRLSRGTLAYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PPAPWSSLATPSALLGSSCAPPPPPARCPQPRALSPELGTKAGPRRPHRWELPRSPSQGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PPAPWSSLATPSALLGSSCAPPPPPARCPQPRALSPELGTKAGPRRPHRWELPRSPSQGA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 QGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 VICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSG 310 320 330 340 350 360 370 380 390 400 pF1KB7 LFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA ::::::::::::::::::::::::::::::::::::::::: CCDS11 LFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA 370 380 390 400 >>CCDS11832.1 TGIF1 gene_id:7050|Hs108|chr18 (286 aa) initn: 1787 init1: 1787 opt: 1787 Z-score: 1155.9 bits: 222.3 E(32554): 4.6e-58 Smith-Waterman score: 1787; 97.8% identity (98.5% similar) in 275 aa overlap (127-401:12-286) 100 110 120 130 140 150 pF1KB7 ELGTKAGPRRPHRWELPRSPSQGAQGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDL : : . .:::::::::::::::::::::: CCDS11 MTCSGKSCALARSSLTSSQGIVAASGSETEDEDSMDIPLDL 10 20 30 40 160 170 180 190 200 210 pF1KB7 SSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFI 50 60 70 80 90 100 220 230 240 250 260 270 pF1KB7 NARRRLLPDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NARRRLLPDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAG 110 120 130 140 150 160 280 290 300 310 320 330 pF1KB7 PNPTLGRPLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PNPTLGRPLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKN 170 180 190 200 210 220 340 350 360 370 380 390 pF1KB7 FTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQ 230 240 250 260 270 280 400 pF1KB7 AKLTA ::::: CCDS11 AKLTA >>CCDS11833.1 TGIF1 gene_id:7050|Hs108|chr18 (272 aa) initn: 1784 init1: 1784 opt: 1784 Z-score: 1154.3 bits: 221.9 E(32554): 5.6e-58 Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 268 aa overlap (134-401:5-272) 110 120 130 140 150 160 pF1KB7 PRRPHRWELPRSPSQGAQGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSG :::::::::::::::::::::::::::::: CCDS11 MKGKKGIVAASGSETEDEDSMDIPLDLSSSAGSG 10 20 30 170 180 190 200 210 220 pF1KB7 KRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLL 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB7 PDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGR 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB7 PLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLM 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB7 YPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA 220 230 240 250 260 270 >>CCDS11835.1 TGIF1 gene_id:7050|Hs108|chr18 (252 aa) initn: 1688 init1: 1688 opt: 1688 Z-score: 1093.7 bits: 210.6 E(32554): 1.3e-54 Smith-Waterman score: 1688; 100.0% identity (100.0% similar) in 252 aa overlap (150-401:1-252) 120 130 140 150 160 170 pF1KB7 AQGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQIL :::::::::::::::::::::::::::::: CCDS11 MDIPLDLSSSAGSGKRRRRGNLPKESVQIL 10 20 30 180 190 200 210 220 230 pF1KB7 RDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTI 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB7 SRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARP 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB7 SVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQS 160 170 180 190 200 210 360 370 380 390 400 pF1KB7 GLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA :::::::::::::::::::::::::::::::::::::::::: CCDS11 GLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA 220 230 240 250 >>CCDS13278.1 TGIF2 gene_id:60436|Hs108|chr20 (237 aa) initn: 745 init1: 515 opt: 533 Z-score: 360.1 bits: 74.7 E(32554): 9.8e-14 Smith-Waterman score: 661; 49.6% identity (64.7% similar) in 252 aa overlap (148-398:3-217) 120 130 140 150 160 170 pF1KB7 QGAQGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQ :: :. : . . .:::.::::::::::. CCDS13 MSDS-DLGEDEGLLSLAGKRKRRGNLPKESVK 10 20 30 180 190 200 210 220 230 pF1KB7 ILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQF ::::::: :::::::::::: :: ::.::.::.:::::::::::::::::::::::::: CCDS13 ILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQF 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB7 TISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLA ::::::.: :... .: : .:.. : :.. : :. CCDS13 TISRRGGKASDVA-----------LPR-----------GSSPSVLAVSVPAPTNVLS-LS 100 110 120 300 310 320 330 340 350 pF1KB7 RPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNT :. :. .:: :. . . ... . : : : : .: CCDS13 VCSMPLHSGQGEKPAAPFPR------GELESPKPLVTPGSTLTLLTRAEAGSPTG----- 130 140 150 160 170 360 370 380 390 400 pF1KB7 QSGLFNTPPPTPPDLNQ-DFSGFQLLVDVALKRAAEMELQAKLTA :::::::::::. .. :::.:::::.:::.:::::::: . CCDS13 --GLFNTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSEN 180 190 200 210 220 230 CCDS13 PQ 401 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:18:09 2016 done: Sat Nov 5 10:18:09 2016 Total Scan time: 3.730 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]