FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7967, 283 aa 1>>>pF1KB7967 283 - 283 aa - 283 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.6052+/-0.000948; mu= -4.0140+/- 0.056 mean_var=310.3237+/-70.107, 0's: 0 Z-trim(114.6): 698 B-trim: 0 in 0/51 Lambda= 0.072806 statistics sampled from 14302 (15159) to 14302 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.466), width: 16 Scan time: 2.210 The best scores are: opt bits E(32554) CCDS7060.1 KLF6 gene_id:1316|Hs108|chr10 ( 283) 1966 219.5 2.3e-57 CCDS53490.1 KLF6 gene_id:1316|Hs108|chr10 ( 237) 1537 174.3 7.3e-44 CCDS2373.1 KLF7 gene_id:8609|Hs108|chr2 ( 302) 703 86.8 2e-17 CCDS59440.1 KLF7 gene_id:8609|Hs108|chr2 ( 269) 698 86.2 2.7e-17 CCDS59438.1 KLF7 gene_id:8609|Hs108|chr2 ( 274) 698 86.3 2.7e-17 CCDS9449.1 KLF12 gene_id:11278|Hs108|chr13 ( 402) 586 74.7 1.2e-13 CCDS3444.1 KLF3 gene_id:51274|Hs108|chr4 ( 345) 576 73.5 2.3e-13 CCDS66562.1 KLF5 gene_id:688|Hs108|chr13 ( 366) 564 72.3 5.8e-13 CCDS9448.1 KLF5 gene_id:688|Hs108|chr13 ( 457) 564 72.4 6.8e-13 CCDS14373.1 KLF8 gene_id:11279|Hs108|chrX ( 359) 546 70.4 2.1e-12 CCDS6770.2 KLF4 gene_id:9314|Hs108|chr9 ( 479) 540 69.9 4e-12 CCDS12285.1 KLF1 gene_id:10661|Hs108|chr19 ( 362) 531 68.8 6.3e-12 CCDS12343.1 KLF2 gene_id:10365|Hs108|chr19 ( 355) 524 68.1 1e-11 >>CCDS7060.1 KLF6 gene_id:1316|Hs108|chr10 (283 aa) initn: 1966 init1: 1966 opt: 1966 Z-score: 1143.5 bits: 219.5 E(32554): 2.3e-57 Smith-Waterman score: 1966; 100.0% identity (100.0% similar) in 283 aa overlap (1-283:1-283) 10 20 30 40 50 60 pF1KB7 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWR 190 200 210 220 230 240 250 260 270 280 pF1KB7 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL ::::::::::::::::::::::::::::::::::::::::::: CCDS70 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL 250 260 270 280 >>CCDS53490.1 KLF6 gene_id:1316|Hs108|chr10 (237 aa) initn: 1600 init1: 1524 opt: 1537 Z-score: 900.9 bits: 174.3 E(32554): 7.3e-44 Smith-Waterman score: 1537; 97.4% identity (97.9% similar) in 234 aa overlap (1-234:1-234) 10 20 30 40 50 60 pF1KB7 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWR :::::::::::::::::::::::::::::::::::::::::::::: : .: CCDS53 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGVFPGLTTWPCT 190 200 210 220 230 250 260 270 280 pF1KB7 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL >>CCDS2373.1 KLF7 gene_id:8609|Hs108|chr2 (302 aa) initn: 1099 init1: 661 opt: 703 Z-score: 426.2 bits: 86.8 E(32554): 2e-17 Smith-Waterman score: 930; 51.9% identity (66.8% similar) in 316 aa overlap (1-283:1-302) 10 20 30 40 50 60 pF1KB7 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ :::: :::::::.::.:::::::::::: :::::::::::::.:: .: . : CCDS23 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISET---FG-- 10 20 30 40 50 70 80 90 100 110 pF1KB7 EDLWTKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEE ::: .. : ::: .. : :. : : .: . . :... :: CCDS23 EDL-DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSET 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 LSPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP----- .:. . . :....:.. .. :::::::::: . :: . : : . CCDS23 CLSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVA 110 120 130 140 150 160 180 190 200 pF1KB7 ---------------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGC . : :.:: : . :.:. ..: :....:::::.:::: CCDS23 KKAALSSVKVGGVATAAAAVTAAGAVKSGQSDS--DQGGLGAEACPENKKRVHRCQFNGC 170 180 190 200 210 220 210 220 230 240 250 260 pF1KB7 RKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDR :::::::::::::::::::::::.:::::::::::::::::::.:::::::::::.:::: CCDS23 RKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDR 230 240 250 260 270 280 270 280 pF1KB7 CFSRSDHLALHMKRHL :::::::::::::::. CCDS23 CFSRSDHLALHMKRHI 290 300 >>CCDS59440.1 KLF7 gene_id:8609|Hs108|chr2 (269 aa) initn: 915 init1: 661 opt: 698 Z-score: 424.0 bits: 86.2 E(32554): 2.7e-17 Smith-Waterman score: 746; 48.2% identity (64.2% similar) in 282 aa overlap (35-283:2-269) 10 20 30 40 50 60 pF1KB7 PMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLW ::::::::::.:: .: . : ::: CCDS59 MTCLELERYLQTEPRRISET---FG--EDL- 10 20 70 80 90 100 110 120 pF1KB7 TKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELSPT .. : ::: .. : :. : : .: . . :... :: CCDS59 DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSL 30 40 50 60 70 130 140 150 160 170 pF1KB7 AKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP--------- .:. . . :....:.. .. :::::::::: . :: . : : . CCDS59 QPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAA 80 90 100 110 120 130 180 190 200 210 pF1KB7 -----------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGCRKVY . : :.:: : .:.:. ..: :....:::::.:::::::: CCDS59 LSSVKVGGVATAAAAVTAAGAVKSGQSD--SDQGGLGAEACPENKKRVHRCQFNGCRKVY 140 150 160 170 180 190 220 230 240 250 260 270 pF1KB7 TKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSR :::::::::::::::::::.:::::::::::::::::::.:::::::::::.:::::::: CCDS59 TKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSR 200 210 220 230 240 250 280 pF1KB7 SDHLALHMKRHL :::::::::::. CCDS59 SDHLALHMKRHI 260 >>CCDS59438.1 KLF7 gene_id:8609|Hs108|chr2 (274 aa) initn: 915 init1: 661 opt: 698 Z-score: 423.9 bits: 86.3 E(32554): 2.7e-17 Smith-Waterman score: 748; 48.1% identity (63.9% similar) in 285 aa overlap (32-283:5-274) 10 20 30 40 50 60 pF1KB7 DVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQE : ::::::::::.:: .: . : : CCDS59 MFPSWP-TCLELERYLQTEPRRISET---FG--E 10 20 70 80 90 100 110 pF1KB7 DLWTKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEEL :: .. : ::: .. : :. : : .: . . :... :: CCDS59 DL-DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSETC 30 40 50 60 70 80 120 130 140 150 160 170 pF1KB7 SPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP------ .:. . . :....:.. .. :::::::::: . :: . : : . CCDS59 LSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAK 90 100 110 120 130 140 180 190 200 pF1KB7 --------------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGCR . : :.:: : . :.:. ..: :....:::::.::::: CCDS59 KAALSSVKVGGVATAAAAVTAAGAVKSGQSDS--DQGGLGAEACPENKKRVHRCQFNGCR 150 160 170 180 190 210 220 230 240 250 260 pF1KB7 KVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRC ::::::::::::::::::::::.:::::::::::::::::::.:::::::::::.::::: CCDS59 KVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRC 200 210 220 230 240 250 270 280 pF1KB7 FSRSDHLALHMKRHL ::::::::::::::. CCDS59 FSRSDHLALHMKRHI 260 270 >>CCDS9449.1 KLF12 gene_id:11278|Hs108|chr13 (402 aa) initn: 783 init1: 559 opt: 586 Z-score: 358.2 bits: 74.7 E(32554): 1.2e-13 Smith-Waterman score: 600; 52.0% identity (72.3% similar) in 173 aa overlap (113-283:238-400) 90 100 110 120 130 140 pF1KB7 SSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELSPTAKFTS-DPIGEVLVSSGKLS :::... :.. . : . : . .: .. CCDS94 NTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAV 210 220 230 240 250 260 150 160 170 180 190 200 pF1KB7 SSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTSGKPGDKGNGDASPDGR-RRVH . : .: : . .: .: . : :: ...: . .. :::.: ::.: CCDS94 QEVHPSPVSRVRGNRMNNQKFPCS----ISPFSIESTRRQRRSE------SPDSRKRRIH 270 280 290 300 310 210 220 230 240 250 260 pF1KB7 RCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPF :: :.:: ::::::::::::.:::::::::.:.:::: :.::::::::::.:::::.::: CCDS94 RCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPF 320 330 340 350 360 370 270 280 pF1KB7 KCSHCDRCFSRSDHLALHMKRHL ::. ::: :::::::::: .::. CCDS94 KCADCDRSFSRSDHLALHRRRHMLV 380 390 400 >>CCDS3444.1 KLF3 gene_id:51274|Hs108|chr4 (345 aa) initn: 747 init1: 557 opt: 576 Z-score: 353.4 bits: 73.5 E(32554): 2.3e-13 Smith-Waterman score: 576; 72.1% identity (83.7% similar) in 104 aa overlap (182-283:240-343) 160 170 180 190 200 pF1KB7 PELSREPSQLWGCVPGELPSPGKVRSGTSGKPGDKGNGDASPDG--RRRVHRCHFNGCRK .:: . ::: .::.::: ..:: : CCDS34 YYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNK 210 220 230 240 250 260 210 220 230 240 250 260 pF1KB7 VYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCF :::::::::::.:::::::::.:.:::: :.:::::::::::::::: :::.: ::: : CCDS34 VYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSF 270 280 290 300 310 320 270 280 pF1KB7 SRSDHLALHMKRHL ::::::::: :::. CCDS34 SRSDHLALHRKRHMLV 330 340 >>CCDS66562.1 KLF5 gene_id:688|Hs108|chr13 (366 aa) initn: 572 init1: 552 opt: 564 Z-score: 346.2 bits: 72.3 E(32554): 5.8e-13 Smith-Waterman score: 564; 62.0% identity (75.9% similar) in 137 aa overlap (147-282:232-364) 120 130 140 150 160 170 pF1KB7 EELSPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVR ::: : . :.: :. ::. : CCDS66 LPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPS-YAATIASKLAIHNPN-LPTTLPVN 210 220 230 240 250 180 190 200 210 220 230 pF1KB7 SGTSGKPGDKGNGDASPD-GRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWE : . .: . : ..:: .::.: : . :: :::::::::::: :::::::::.:.:: CCDS66 S-QNIQPV-RYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWE 260 270 280 290 300 310 240 250 260 270 280 pF1KB7 GCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL ::.::::::::::::.:::::::::.:. :.: :::::::::::::: CCDS66 GCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN 320 330 340 350 360 >>CCDS9448.1 KLF5 gene_id:688|Hs108|chr13 (457 aa) initn: 592 init1: 552 opt: 564 Z-score: 345.0 bits: 72.4 E(32554): 6.8e-13 Smith-Waterman score: 564; 62.0% identity (75.9% similar) in 137 aa overlap (147-282:323-455) 120 130 140 150 160 170 pF1KB7 EELSPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVR ::: : . :.: :. ::. : CCDS94 LPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPS-YAATIASKLAIHNPN-LPTTLPVN 300 310 320 330 340 350 180 190 200 210 220 230 pF1KB7 SGTSGKPGDKGNGDASPD-GRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWE : . .: . : ..:: .::.: : . :: :::::::::::: :::::::::.:.:: CCDS94 S-QNIQPV-RYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWE 360 370 380 390 400 240 250 260 270 280 pF1KB7 GCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL ::.::::::::::::.:::::::::.:. :.: :::::::::::::: CCDS94 GCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN 410 420 430 440 450 >>CCDS14373.1 KLF8 gene_id:11279|Hs108|chrX (359 aa) initn: 559 init1: 537 opt: 546 Z-score: 336.1 bits: 70.4 E(32554): 2.1e-12 Smith-Waterman score: 548; 58.3% identity (75.8% similar) in 132 aa overlap (166-282:225-356) 140 150 160 170 180 pF1KB7 SSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGK---VRSGTSGKPGDKG----- : :.:: .. ..::.:. . .: CCDS14 DGGPAAITVPLIGGDGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQEP 200 210 220 230 240 250 190 200 210 220 230 240 pF1KB7 ------NGDASPD-GRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWR .:. : : :::.:.: : :: ::::::::::::.: :::::::.:.:.:: :. CCDS14 AAMAQMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWK 260 270 280 290 300 310 250 260 270 280 pF1KB7 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL :::::::::::::::: :::.:. :.: :::::::.:: .:: CCDS14 FARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM 320 330 340 350 283 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:18:42 2016 done: Sat Nov 5 10:18:43 2016 Total Scan time: 2.210 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]