FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7967, 283 aa 1>>>pF1KB7967 283 - 283 aa - 283 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.7203+/-0.000389; mu= -4.4218+/- 0.024 mean_var=396.4053+/-91.597, 0's: 0 Z-trim(122.4): 1179 B-trim: 2100 in 1/53 Lambda= 0.064418 statistics sampled from 38799 (40526) to 38799 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.475), width: 16 Scan time: 8.250 The best scores are: opt bits E(85289) NP_001291 (OMIM: 176807,602053,613659) Krueppel-li ( 283) 1966 196.2 5.9e-50 NP_001153597 (OMIM: 176807,602053,613659) Krueppel ( 237) 1537 156.3 5.3e-38 NP_001153596 (OMIM: 176807,602053,613659) Krueppel ( 241) 1224 127.2 3e-29 NP_003700 (OMIM: 604865) Krueppel-like factor 7 is ( 302) 703 78.9 1.3e-14 XP_016860650 (OMIM: 604865) PREDICTED: Krueppel-li ( 302) 703 78.9 1.3e-14 NP_001257872 (OMIM: 604865) Krueppel-like factor 7 ( 269) 698 78.3 1.7e-14 NP_001257873 (OMIM: 604865) Krueppel-like factor 7 ( 274) 698 78.4 1.7e-14 XP_011510376 (OMIM: 604865) PREDICTED: Krueppel-li ( 270) 678 76.5 6.1e-14 XP_011510375 (OMIM: 604865) PREDICTED: Krueppel-li ( 272) 678 76.5 6.2e-14 XP_016860651 (OMIM: 604865) PREDICTED: Krueppel-li ( 275) 678 76.5 6.2e-14 XP_006712878 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 678 76.6 6.6e-14 XP_005246983 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 678 76.6 6.6e-14 XP_011510374 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 678 76.6 6.6e-14 XP_016875874 (OMIM: 607531) PREDICTED: Krueppel-li ( 352) 586 68.1 2.7e-11 XP_011533214 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 586 68.1 2.9e-11 XP_011533213 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 586 68.1 2.9e-11 XP_016875873 (OMIM: 607531) PREDICTED: Krueppel-li ( 393) 586 68.1 2.9e-11 XP_011533212 (OMIM: 607531) PREDICTED: Krueppel-li ( 400) 586 68.2 2.9e-11 XP_005266308 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 586 68.2 3e-11 NP_009180 (OMIM: 607531) Krueppel-like factor 12 [ ( 402) 586 68.2 3e-11 XP_011533211 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 586 68.2 3e-11 XP_011533209 (OMIM: 607531) PREDICTED: Krueppel-li ( 415) 586 68.2 3e-11 XP_016863768 (OMIM: 609392) PREDICTED: Krueppel-li ( 320) 576 67.1 4.9e-11 NP_057615 (OMIM: 609392) Krueppel-like factor 3 [H ( 345) 576 67.1 5.1e-11 NP_001273747 (OMIM: 602903) Krueppel-like factor 5 ( 366) 564 66.1 1.1e-10 NP_001721 (OMIM: 602903) Krueppel-like factor 5 is ( 457) 564 66.2 1.3e-10 XP_016884739 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 546 64.4 3.6e-10 XP_011529061 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 546 64.4 3.6e-10 NP_001311034 (OMIM: 300286) Krueppel-like factor 8 ( 356) 546 64.4 3.6e-10 NP_009181 (OMIM: 300286) Krueppel-like factor 8 is ( 359) 546 64.4 3.6e-10 XP_005262036 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 546 64.4 3.6e-10 XP_005262034 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 546 64.4 3.6e-10 NP_001311031 (OMIM: 300286) Krueppel-like factor 8 ( 359) 546 64.4 3.6e-10 NP_001311033 (OMIM: 300286) Krueppel-like factor 8 ( 364) 546 64.4 3.6e-10 NP_004226 (OMIM: 602253) Krueppel-like factor 4 is ( 479) 540 64.0 6.4e-10 XP_011525944 (OMIM: 111150,600599,613566,613673) P ( 324) 531 62.9 8.9e-10 NP_006554 (OMIM: 111150,600599,613566,613673) Krue ( 362) 531 63.0 9.6e-10 NP_001300981 (OMIM: 602253) Krueppel-like factor 4 ( 513) 533 63.4 1e-09 NP_057354 (OMIM: 602016) Krueppel-like factor 2 [H ( 355) 524 62.3 1.5e-09 NP_057079 (OMIM: 605328,612001) Krueppel-like fact ( 288) 476 57.8 2.9e-08 XP_005247457 (OMIM: 606465) PREDICTED: Krueppel-li ( 416) 465 56.9 7.3e-08 NP_054798 (OMIM: 606465) Krueppel-like factor 15 [ ( 416) 465 56.9 7.3e-08 XP_011511045 (OMIM: 606465) PREDICTED: Krueppel-li ( 435) 465 57.0 7.5e-08 NP_619638 (OMIM: 609393) Krueppel-like factor 14 [ ( 323) 448 55.2 1.9e-07 NP_114124 (OMIM: 606139) Krueppel-like factor 16 [ ( 252) 445 54.8 1.9e-07 NP_001027453 (OMIM: 601878) Krueppel-like factor 1 ( 469) 444 55.0 3.1e-07 NP_005646 (OMIM: 601878) Krueppel-like factor 10 i ( 480) 444 55.1 3.1e-07 NP_001171187 (OMIM: 603301,610508) Krueppel-like f ( 495) 443 55.0 3.4e-07 NP_001171189 (OMIM: 603301,610508) Krueppel-like f ( 495) 443 55.0 3.4e-07 NP_003588 (OMIM: 603301,610508) Krueppel-like fact ( 512) 443 55.0 3.4e-07 >>NP_001291 (OMIM: 176807,602053,613659) Krueppel-like f (283 aa) initn: 1966 init1: 1966 opt: 1966 Z-score: 1017.9 bits: 196.2 E(85289): 5.9e-50 Smith-Waterman score: 1966; 100.0% identity (100.0% similar) in 283 aa overlap (1-283:1-283) 10 20 30 40 50 60 pF1KB7 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWR 190 200 210 220 230 240 250 260 270 280 pF1KB7 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL ::::::::::::::::::::::::::::::::::::::::::: NP_001 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL 250 260 270 280 >>NP_001153597 (OMIM: 176807,602053,613659) Krueppel-lik (237 aa) initn: 1600 init1: 1524 opt: 1537 Z-score: 803.3 bits: 156.3 E(85289): 5.3e-38 Smith-Waterman score: 1537; 97.4% identity (97.9% similar) in 234 aa overlap (1-234:1-234) 10 20 30 40 50 60 pF1KB7 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWR :::::::::::::::::::::::::::::::::::::::::::::: : .: NP_001 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGVFPGLTTWPCT 190 200 210 220 230 250 260 270 280 pF1KB7 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL >>NP_001153596 (OMIM: 176807,602053,613659) Krueppel-lik (241 aa) initn: 1250 init1: 1224 opt: 1224 Z-score: 646.0 bits: 127.2 E(85289): 3e-29 Smith-Waterman score: 1564; 85.2% identity (85.2% similar) in 283 aa overlap (1-283:1-241) 10 20 30 40 50 60 pF1KB7 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWR :::: :::::::::::::: NP_001 GKPG------------------------------------------EKPYRCSWEGCEWR 190 250 260 270 280 pF1KB7 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL ::::::::::::::::::::::::::::::::::::::::::: NP_001 FARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL 200 210 220 230 240 >>NP_003700 (OMIM: 604865) Krueppel-like factor 7 isofor (302 aa) initn: 1099 init1: 661 opt: 703 Z-score: 383.2 bits: 78.9 E(85289): 1.3e-14 Smith-Waterman score: 930; 51.9% identity (66.8% similar) in 316 aa overlap (1-283:1-302) 10 20 30 40 50 60 pF1KB7 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ :::: :::::::.::.:::::::::::: :::::::::::::.:: .: . : NP_003 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISET---FG-- 10 20 30 40 50 70 80 90 100 110 pF1KB7 EDLWTKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEE ::: .. : ::: .. : :. : : .: . . :... :: NP_003 EDL-DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSET 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 LSPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP----- .:. . . :....:.. .. :::::::::: . :: . : : . NP_003 CLSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVA 110 120 130 140 150 160 180 190 200 pF1KB7 ---------------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGC . : :.:: : . :.:. ..: :....:::::.:::: NP_003 KKAALSSVKVGGVATAAAAVTAAGAVKSGQSDS--DQGGLGAEACPENKKRVHRCQFNGC 170 180 190 200 210 220 210 220 230 240 250 260 pF1KB7 RKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDR :::::::::::::::::::::::.:::::::::::::::::::.:::::::::::.:::: NP_003 RKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDR 230 240 250 260 270 280 270 280 pF1KB7 CFSRSDHLALHMKRHL :::::::::::::::. NP_003 CFSRSDHLALHMKRHI 290 300 >>XP_016860650 (OMIM: 604865) PREDICTED: Krueppel-like f (302 aa) initn: 1099 init1: 661 opt: 703 Z-score: 383.2 bits: 78.9 E(85289): 1.3e-14 Smith-Waterman score: 930; 51.9% identity (66.8% similar) in 316 aa overlap (1-283:1-302) 10 20 30 40 50 60 pF1KB7 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ :::: :::::::.::.:::::::::::: :::::::::::::.:: .: . : XP_016 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISET---FG-- 10 20 30 40 50 70 80 90 100 110 pF1KB7 EDLWTKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEE ::: .. : ::: .. : :. : : .: . . :... :: XP_016 EDL-DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSET 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 LSPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP----- .:. . . :....:.. .. :::::::::: . :: . : : . XP_016 CLSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVA 110 120 130 140 150 160 180 190 200 pF1KB7 ---------------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGC . : :.:: : . :.:. ..: :....:::::.:::: XP_016 KKAALSSVKVGGVATAAAAVTAAGAVKSGQSDS--DQGGLGAEACPENKKRVHRCQFNGC 170 180 190 200 210 220 210 220 230 240 250 260 pF1KB7 RKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDR :::::::::::::::::::::::.:::::::::::::::::::.:::::::::::.:::: XP_016 RKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDR 230 240 250 260 270 280 270 280 pF1KB7 CFSRSDHLALHMKRHL :::::::::::::::. XP_016 CFSRSDHLALHMKRHI 290 300 >>NP_001257872 (OMIM: 604865) Krueppel-like factor 7 iso (269 aa) initn: 915 init1: 661 opt: 698 Z-score: 381.3 bits: 78.3 E(85289): 1.7e-14 Smith-Waterman score: 746; 48.2% identity (64.2% similar) in 282 aa overlap (35-283:2-269) 10 20 30 40 50 60 pF1KB7 PMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLW ::::::::::.:: .: . : ::: NP_001 MTCLELERYLQTEPRRISET---FG--EDL- 10 20 70 80 90 100 110 120 pF1KB7 TKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELSPT .. : ::: .. : :. : : .: . . :... :: NP_001 DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSL 30 40 50 60 70 130 140 150 160 170 pF1KB7 AKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP--------- .:. . . :....:.. .. :::::::::: . :: . : : . NP_001 QPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAA 80 90 100 110 120 130 180 190 200 210 pF1KB7 -----------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGCRKVY . : :.:: : .:.:. ..: :....:::::.:::::::: NP_001 LSSVKVGGVATAAAAVTAAGAVKSGQSD--SDQGGLGAEACPENKKRVHRCQFNGCRKVY 140 150 160 170 180 190 220 230 240 250 260 270 pF1KB7 TKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSR :::::::::::::::::::.:::::::::::::::::::.:::::::::::.:::::::: NP_001 TKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSR 200 210 220 230 240 250 280 pF1KB7 SDHLALHMKRHL :::::::::::. NP_001 SDHLALHMKRHI 260 >>NP_001257873 (OMIM: 604865) Krueppel-like factor 7 iso (274 aa) initn: 915 init1: 661 opt: 698 Z-score: 381.2 bits: 78.4 E(85289): 1.7e-14 Smith-Waterman score: 748; 48.1% identity (63.9% similar) in 285 aa overlap (32-283:5-274) 10 20 30 40 50 60 pF1KB7 DVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQE : ::::::::::.:: .: . : : NP_001 MFPSWP-TCLELERYLQTEPRRISET---FG--E 10 20 70 80 90 100 110 pF1KB7 DLWTKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEEL :: .. : ::: .. : :. : : .: . . :... :: NP_001 DL-DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSETC 30 40 50 60 70 80 120 130 140 150 160 170 pF1KB7 SPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP------ .:. . . :....:.. .. :::::::::: . :: . : : . NP_001 LSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAK 90 100 110 120 130 140 180 190 200 pF1KB7 --------------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGCR . : :.:: : . :.:. ..: :....:::::.::::: NP_001 KAALSSVKVGGVATAAAAVTAAGAVKSGQSDS--DQGGLGAEACPENKKRVHRCQFNGCR 150 160 170 180 190 210 220 230 240 250 260 pF1KB7 KVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRC ::::::::::::::::::::::.:::::::::::::::::::.:::::::::::.::::: NP_001 KVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRC 200 210 220 230 240 250 270 280 pF1KB7 FSRSDHLALHMKRHL ::::::::::::::. NP_001 FSRSDHLALHMKRHI 260 270 >>XP_011510376 (OMIM: 604865) PREDICTED: Krueppel-like f (270 aa) initn: 888 init1: 427 opt: 678 Z-score: 371.2 bits: 76.5 E(85289): 6.1e-14 Smith-Waterman score: 734; 48.1% identity (64.0% similar) in 283 aa overlap (35-283:2-270) 10 20 30 40 50 60 pF1KB7 PMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLW ::::::::::.:: .: . : ::: XP_011 MTCLELERYLQTEPRRISET---FG--EDL- 10 20 70 80 90 100 110 120 pF1KB7 TKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELSPT .. : ::: .. : :. : : .: . . :... :: XP_011 DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSL 30 40 50 60 70 130 140 150 160 170 pF1KB7 AKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP--------- .:. . . :....:.. .. :::::::::: . :: . : : . XP_011 QPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAA 80 90 100 110 120 130 180 190 200 210 pF1KB7 -----------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGCRKVY . : :.:: : .:.:. ..: :....:::::.:::::::: XP_011 LSSVKVGGVATAAAAVTAAGAVKSGQSD--SDQGGLGAEACPENKKRVHRCQFNGCRKVY 140 150 160 170 180 190 220 230 240 250 260 270 pF1KB7 TKSSHLKAHQRTHTG-EKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFS ::::::::::::::: ::::.:::::::::::::::::::.:::::::::::.::::::: XP_011 TKSSHLKAHQRTHTGSEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFS 200 210 220 230 240 250 280 pF1KB7 RSDHLALHMKRHL ::::::::::::. XP_011 RSDHLALHMKRHI 260 270 >>XP_011510375 (OMIM: 604865) PREDICTED: Krueppel-like f (272 aa) initn: 895 init1: 427 opt: 678 Z-score: 371.2 bits: 76.5 E(85289): 6.2e-14 Smith-Waterman score: 741; 48.2% identity (64.1% similar) in 284 aa overlap (34-283:3-272) 10 20 30 40 50 60 pF1KB7 LPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDL :::::::::::.:: .: . : ::: XP_011 MTQTCLELERYLQTEPRRISET---FG--EDL 10 20 70 80 90 100 110 120 pF1KB7 WTKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELSP .. : ::: .. : :. : : .: . . :... :: XP_011 -DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSETCLS 30 40 50 60 70 80 130 140 150 160 170 pF1KB7 TAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP-------- .:. . . :....:.. .. :::::::::: . :: . : : . XP_011 LQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKA 90 100 110 120 130 140 180 190 200 210 pF1KB7 ------------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGCRKV . : :.:: : .:.:. ..: :....:::::.::::::: XP_011 ALSSVKVGGVATAAAAVTAAGAVKSGQSD--SDQGGLGAEACPENKKRVHRCQFNGCRKV 150 160 170 180 190 220 230 240 250 260 pF1KB7 YTKSSHLKAHQRTHTG-EKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCF :::::::::::::::: ::::.:::::::::::::::::::.:::::::::::.:::::: XP_011 YTKSSHLKAHQRTHTGSEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCF 200 210 220 230 240 250 270 280 pF1KB7 SRSDHLALHMKRHL :::::::::::::. XP_011 SRSDHLALHMKRHI 260 270 >>XP_016860651 (OMIM: 604865) PREDICTED: Krueppel-like f (275 aa) initn: 888 init1: 427 opt: 678 Z-score: 371.1 bits: 76.5 E(85289): 6.2e-14 Smith-Waterman score: 736; 47.9% identity (63.6% similar) in 286 aa overlap (32-283:5-275) 10 20 30 40 50 60 pF1KB7 DVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQE : ::::::::::.:: .: . : : XP_016 MFPSWP-TCLELERYLQTEPRRISET---FG--E 10 20 70 80 90 100 110 pF1KB7 DLWTKIILAREKK--EESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEEL :: .. : ::: .. : :. : : .: . . :... :: XP_016 DL-DCFLHASPPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSETC 30 40 50 60 70 80 120 130 140 150 160 170 pF1KB7 SPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGELP------ .:. . . :....:.. .. :::::::::: . :: . : : . XP_016 LSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAK 90 100 110 120 130 140 180 190 200 pF1KB7 --------------------SPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGCR . : :.:: : . :.:. ..: :....:::::.::::: XP_016 KAALSSVKVGGVATAAAAVTAAGAVKSGQSDS--DQGGLGAEACPENKKRVHRCQFNGCR 150 160 170 180 190 210 220 230 240 250 260 pF1KB7 KVYTKSSHLKAHQRTHTG-EKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDR :::::::::::::::::: ::::.:::::::::::::::::::.:::::::::::.:::: XP_016 KVYTKSSHLKAHQRTHTGSEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDR 200 210 220 230 240 250 270 280 pF1KB7 CFSRSDHLALHMKRHL :::::::::::::::. XP_016 CFSRSDHLALHMKRHI 260 270 283 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:18:43 2016 done: Sat Nov 5 10:18:44 2016 Total Scan time: 8.250 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]