Result of FASTA (omim) for
pF1KB7968
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7968, 407 aa
1>>>pF1KB7968 407 - 407 aa - 407 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3945+/-0.000424; mu= 4.4189+/- 0.026
mean_var=287.8506+/-60.146, 0's: 0 Z-trim(120.4): 1837 B-trim: 0 in 0/54
Lambda= 0.075595
statistics sampled from 33432 (35645) to 33432 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.418), width: 16
Scan time: 10.040
The best scores are: opt bits E(85289)
NP_003441 (OMIM: 603900) zinc finger protein 174 i ( 407) 2854 324.7 2.5e-88
NP_001027463 (OMIM: 603900) zinc finger protein 17 ( 234) 1429 169.0 1.1e-41
XP_011513319 (OMIM: 603978) PREDICTED: zinc finger ( 565) 753 95.7 3e-19
XP_011525219 (OMIM: 165260) PREDICTED: zinc finger ( 491) 744 94.7 5.3e-19
NP_001308045 (OMIM: 165260) zinc finger and SCAN d ( 491) 744 94.7 5.3e-19
NP_862829 (OMIM: 165260) zinc finger and SCAN doma ( 491) 744 94.7 5.3e-19
XP_006723255 (OMIM: 165260) PREDICTED: zinc finger ( 491) 744 94.7 5.3e-19
NP_112161 (OMIM: 610794) zinc finger and SCAN doma ( 406) 730 93.1 1.4e-18
XP_011513109 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
XP_011513110 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
XP_011513115 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
XP_005249352 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
XP_011513111 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
XP_016866685 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
NP_001128687 (OMIM: 610794) zinc finger and SCAN d ( 406) 730 93.1 1.4e-18
XP_005249353 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
NP_665916 (OMIM: 610794) zinc finger and SCAN doma ( 406) 730 93.1 1.4e-18
NP_001128688 (OMIM: 610794) zinc finger and SCAN d ( 406) 730 93.1 1.4e-18
XP_011513113 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
XP_011513114 (OMIM: 610794) PREDICTED: zinc finger ( 406) 730 93.1 1.4e-18
NP_001230170 (OMIM: 610794) zinc finger and SCAN d ( 406) 730 93.1 1.4e-18
NP_001307883 (OMIM: 616463) zinc finger protein 23 ( 417) 702 90.0 1.2e-17
NP_001307882 (OMIM: 616463) zinc finger protein 23 ( 417) 702 90.0 1.2e-17
NP_055334 (OMIM: 616463) zinc finger protein 232 i ( 444) 702 90.1 1.2e-17
XP_016880510 (OMIM: 616463) PREDICTED: zinc finger ( 444) 702 90.1 1.2e-17
XP_011522308 (OMIM: 616463) PREDICTED: zinc finger ( 396) 695 89.2 1.9e-17
NP_001186408 (OMIM: 602246) zinc finger and SCAN d ( 445) 681 87.8 5.9e-17
XP_011513178 (OMIM: 602246) PREDICTED: zinc finger ( 577) 681 87.9 6.9e-17
NP_003413 (OMIM: 194550) myeloid zinc finger 1 iso ( 734) 672 87.0 1.6e-16
NP_932172 (OMIM: 194550) myeloid zinc finger 1 iso ( 734) 672 87.0 1.6e-16
XP_011525566 (OMIM: 194550) PREDICTED: myeloid zin ( 764) 672 87.1 1.6e-16
XP_005259261 (OMIM: 194550) PREDICTED: myeloid zin ( 775) 672 87.1 1.7e-16
XP_011513177 (OMIM: 602246) PREDICTED: zinc finger ( 583) 660 85.6 3.4e-16
XP_006720896 (OMIM: 604191) PREDICTED: zinc finger ( 598) 657 85.3 4.4e-16
XP_016867412 (OMIM: 611272) PREDICTED: zinc finger ( 766) 652 84.9 7.4e-16
NP_001305012 (OMIM: 611272) zinc finger protein wi ( 766) 652 84.9 7.4e-16
XP_016867413 (OMIM: 611272) PREDICTED: zinc finger ( 766) 652 84.9 7.4e-16
NP_001186409 (OMIM: 602246) zinc finger and SCAN d ( 394) 624 81.5 4e-15
NP_006290 (OMIM: 602246) zinc finger and SCAN doma ( 394) 624 81.5 4e-15
XP_016866756 (OMIM: 602246) PREDICTED: zinc finger ( 394) 624 81.5 4e-15
XP_011513180 (OMIM: 602246) PREDICTED: zinc finger ( 526) 624 81.6 4.9e-15
NP_008896 (OMIM: 194534) zinc finger protein 24 is ( 368) 509 68.9 2.3e-11
XP_005258398 (OMIM: 194534) PREDICTED: zinc finger ( 368) 509 68.9 2.3e-11
NP_001253962 (OMIM: 194550) myeloid zinc finger 1 ( 290) 495 67.3 5.7e-11
XP_011541277 (OMIM: 603430) PREDICTED: zinc finger ( 648) 496 67.8 8.8e-11
XP_011541275 (OMIM: 603430) PREDICTED: zinc finger ( 648) 496 67.8 8.8e-11
XP_006718964 (OMIM: 603430) PREDICTED: zinc finger ( 648) 496 67.8 8.8e-11
NP_001288708 (OMIM: 603430) zinc finger protein 20 ( 648) 496 67.8 8.8e-11
XP_005271716 (OMIM: 603430) PREDICTED: zinc finger ( 648) 496 67.8 8.8e-11
XP_005271718 (OMIM: 603430) PREDICTED: zinc finger ( 648) 496 67.8 8.8e-11
>>NP_003441 (OMIM: 603900) zinc finger protein 174 isofo (407 aa)
initn: 2854 init1: 2854 opt: 2854 Z-score: 1706.6 bits: 324.7 E(85289): 2.5e-88
Smith-Waterman score: 2854; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB7 MAAKMEITLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAAKMEITLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QEALSQLRQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QEALSQLRQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VEDFHRASKKPKQWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VEDFHRASKKPKQWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AGAYDRLSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AGAYDRLSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 GNGLQNPEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GNGLQNPEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELKKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECG
310 320 330 340 350 360
370 380 390 400
pF1KB7 NCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
:::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
370 380 390 400
>>NP_001027463 (OMIM: 603900) zinc finger protein 174 is (234 aa)
initn: 1428 init1: 1428 opt: 1429 Z-score: 869.5 bits: 169.0 E(85289): 1.1e-41
Smith-Waterman score: 1429; 97.2% identity (98.1% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KB7 MAAKMEITLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAKMEITLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QEALSQLRQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEALSQLRQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VEDFHRASKKPKQWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDFHRASKKPKQWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AGAYDRLSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSK
::::::::::::::::::::::::::::: ..:
NP_001 AGAYDRLSPHHWEKSPLLQEPTPKLAGTELLIEKTDPNMATDELPCKLWLSFIA
190 200 210 220 230
250 260 270 280 290 300
pF1KB7 GNGLQNPEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELKKS
>>XP_011513319 (OMIM: 603978) PREDICTED: zinc finger and (565 aa)
initn: 1755 init1: 423 opt: 753 Z-score: 466.7 bits: 95.7 E(85289): 3e-19
Smith-Waterman score: 809; 36.8% identity (64.7% similar) in 402 aa overlap (14-407:8-383)
10 20 30 40 50
pF1KB7 MAAKMEITLSSNTEASSKQERHIIAKLEEKRGPPLQ------KNCPDPELCRQSFRRFCY
.: :.. . .:.::.. : .: . :. :: ::.:::
XP_011 MASTWAIQAHMDQDEPLEVKIEEEKYTTRQDWDLRKNNTHSREVFRQYFRQFCY
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 QEVSGPQEALSQLRQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSS
::.:::.::::.::.::.:::.:: :::::::::::.:::::::: :.:: :... : :.
XP_011 QETSGPREALSRLRELCHQWLRPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 KEIVTLVEDFHRASKKPKQWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESS
.:.::..::..: .: . :.: :...:..: .: .. :... :. . . . :
XP_011 EEVVTVLEDLERELDEPGEQVSVHTGEQEMFLQET-VRLRKEGEPSMSLQSMKAQPKYES
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 PA-EPSQAGAYDRLSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNK-ENPQQEGAKGAKPC
: : .: . : . . : . : :: . .. :. ....: :: ....:. :
XP_011 PELESQQEQVLDVETGN--EYGNLKQEVSEEME----PHGKTSSKFENDMSKSAR----C
180 190 200 210 220
240 250 260 270 280 290
pF1KB7 AVSAGRSKGNGLQNPEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSH
. . : . ..: . . ..: .. :: . . : :: :
XP_011 GET--REPEEITEEPSACSREDKQPTCDENGVSLTENSDHTEH-QRIC------------
230 240 250 260
300 310 320 330 340 350
pF1KB7 PLRELKKSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGER
: .: ...:.. . . :: ... .::::..:::.: . : ::: .::::.
XP_011 PGEESYGCDDCGKAFSQHSHLIEHQRIHTGDRPYKCEECGKAFRGRTVLIRHKIIHTGEK
270 280 290 300 310 320
360 370 380 390 400
pF1KB7 PYTCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
:: :.:::. ::: :.:. :::.::::: :.:..:::.: :...: .: ..: :
XP_011 PYKCNECGKAFGRWSALNQHQRLHTGEKHYHCNDCGKAFSQKAGLFHHIKIHTRDKPYQC
330 340 350 360 370 380
XP_011 TQCNKSFSRRSILTQHQGVHTGAKPYECNECGKAFVYNSSLVSHQEIHHKEKCYQCKECG
390 400 410 420 430 440
>--
initn: 1076 init1: 389 opt: 397 Z-score: 256.8 bits: 56.9 E(85289): 1.4e-07
Smith-Waterman score: 397; 37.8% identity (62.8% similar) in 172 aa overlap (248-407:384-550)
220 230 240 250 260 270
pF1KB7 KENPQQEGAKGAKPCAVSAGRSKGNGLQNPEPRGANMSEPRLSRRQVSSPN-----AQKP
.: .. . .:::.. . . . ::
XP_011 GEKHYHCNDCGKAFSQKAGLFHHIKIHTRDKPYQCTQCNKSFSRRSILTQHQGVHTGAKP
360 370 380 390 400 410
280 290 300 310 320
pF1KB7 FAHYQRHCRVEYI-SSPLKSHPLRELK------KSKGGKRSLSNRLQHLGHQPTRSAKKP
. . : .. .: : :: . : : : . : :. .:: : ....::
XP_011 YECNE--CGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLIQH---QRIHTGEKP
420 430 440 450 460
330 340 350 360 370 380
pF1KB7 YKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECGNCFGRQSTLKLHQRIHTGEKPYQCG
:::: : :.: . : .:.:.::::::: : .::. : ..:.: ::::::::.::.:
XP_011 YKCDVCEKAFIQRTSLTEHQRIHTGERPYKCDKCGKAFTQRSVLTEHQRIHTGERPYKCD
470 480 490 500 510 520
390 400
pF1KB7 QCGKSFRQSSNLHQHHRLHHGD
.::..:: ..: ::.:.: :.
XP_011 ECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQR
530 540 550 560
>>XP_011525219 (OMIM: 165260) PREDICTED: zinc finger and (491 aa)
initn: 2652 init1: 412 opt: 744 Z-score: 462.1 bits: 94.7 E(85289): 5.3e-19
Smith-Waterman score: 746; 38.4% identity (62.7% similar) in 383 aa overlap (43-407:46-405)
20 30 40 50 60 70
pF1KB7 TEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGPQEALSQLRQLCR
: : ::.: :.:.:::.:::..:: ::
XP_011 DSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEASGPHEALAHLRALCC
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB7 QWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRASKKPK
:::::: :.:::::::::.:::: ::::::: : . : :..: ..::::. .. : .
XP_011 QWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEAAVLVEDLTQVLDK-R
80 90 100 110 120 130
140 150 160 170 180
pF1KB7 QWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPA-----EPSQAGAYDRL
: .. . :.:::.: :. .: . . :: :: .. . :
XP_011 GWDP---GAEPTEASCKQSDLGESE-PSNVTETLMGGVSLG-PAFVKACEPEGSSERSGL
140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSKGNGLQNP
: . : :: : : .: : :. : .. .: . .:.:..... :
XP_011 SGEIWTKSVTQQIHFKKTSG---PY-----KDVPTDQ--RGRES---GASRNSSSAWPNL
190 200 210 220 230
250 260 270 280 290
pF1KB7 EPRGANMSEPRLSRRQVSSPNAQKPFAHYQ------RHCRVEYIS-SPLKSHPLRELKK-
. :: ... :.. ... :... :.:: . : : :..: . .:
XP_011 TSQEKPPSEDKFD--LVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 ----SKGGKRSLSNRLQHLG-HQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPY
:. :: ..: : ::. :: .... ::..: .:::.:. ..: .:.:.::::.::
XP_011 PYACSECGK-AFS-RSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPY
300 310 320 330 340 350
360 370 380 390 400
pF1KB7 TCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
:::::. :.:.. : :::.::::.::.: :::.: ::..: ::.:.: :.
XP_011 KCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDA
360 370 380 390 400 410
XP_011 CGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKA
420 430 440 450 460 470
>--
initn: 666 init1: 356 opt: 356 Z-score: 233.4 bits: 52.4 E(85289): 2.9e-06
Smith-Waterman score: 356; 56.8% identity (77.8% similar) in 81 aa overlap (324-404:406-486)
300 310 320 330 340 350
pF1KB7 LRELKKSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERP
:::::: ::..:. : : :: :.:.::.:
XP_011 GERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKP
380 390 400 410 420 430
360 370 380 390 400
pF1KB7 YTCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
: : : . :...:.: :::::::::::.:..:::.: .:: : : :.:
XP_011 YQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ
440 450 460 470 480 490
>>NP_001308045 (OMIM: 165260) zinc finger and SCAN domai (491 aa)
initn: 2652 init1: 412 opt: 744 Z-score: 462.1 bits: 94.7 E(85289): 5.3e-19
Smith-Waterman score: 746; 38.4% identity (62.7% similar) in 383 aa overlap (43-407:46-405)
20 30 40 50 60 70
pF1KB7 TEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGPQEALSQLRQLCR
: : ::.: :.:.:::.:::..:: ::
NP_001 DSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEASGPHEALAHLRALCC
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB7 QWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRASKKPK
:::::: :.:::::::::.:::: ::::::: : . : :..: ..::::. .. : .
NP_001 QWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEAAVLVEDLTQVLDK-R
80 90 100 110 120 130
140 150 160 170 180
pF1KB7 QWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPA-----EPSQAGAYDRL
: .. . :.:::.: :. .: . . :: :: .. . :
NP_001 GWDP---GAEPTEASCKQSDLGESE-PSNVTETLMGGVSLG-PAFVKACEPEGSSERSGL
140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSKGNGLQNP
: . : :: : : .: : :. : .. .: . .:.:..... :
NP_001 SGEIWTKSVTQQIHFKKTSG---PY-----KDVPTDQ--RGRES---GASRNSSSAWPNL
190 200 210 220 230
250 260 270 280 290
pF1KB7 EPRGANMSEPRLSRRQVSSPNAQKPFAHYQ------RHCRVEYIS-SPLKSHPLRELKK-
. :: ... :.. ... :... :.:: . : : :..: . .:
NP_001 TSQEKPPSEDKFD--LVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 ----SKGGKRSLSNRLQHLG-HQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPY
:. :: ..: : ::. :: .... ::..: .:::.:. ..: .:.:.::::.::
NP_001 PYACSECGK-AFS-RSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPY
300 310 320 330 340 350
360 370 380 390 400
pF1KB7 TCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
:::::. :.:.. : :::.::::.::.: :::.: ::..: ::.:.: :.
NP_001 KCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDA
360 370 380 390 400 410
NP_001 CGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKA
420 430 440 450 460 470
>--
initn: 666 init1: 356 opt: 356 Z-score: 233.4 bits: 52.4 E(85289): 2.9e-06
Smith-Waterman score: 356; 56.8% identity (77.8% similar) in 81 aa overlap (324-404:406-486)
300 310 320 330 340 350
pF1KB7 LRELKKSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERP
:::::: ::..:. : : :: :.:.::.:
NP_001 GERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKP
380 390 400 410 420 430
360 370 380 390 400
pF1KB7 YTCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
: : : . :...:.: :::::::::::.:..:::.: .:: : : :.:
NP_001 YQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ
440 450 460 470 480 490
>>NP_862829 (OMIM: 165260) zinc finger and SCAN domain-c (491 aa)
initn: 2652 init1: 412 opt: 744 Z-score: 462.1 bits: 94.7 E(85289): 5.3e-19
Smith-Waterman score: 746; 38.4% identity (62.7% similar) in 383 aa overlap (43-407:46-405)
20 30 40 50 60 70
pF1KB7 TEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGPQEALSQLRQLCR
: : ::.: :.:.:::.:::..:: ::
NP_862 DSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEASGPHEALAHLRALCC
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB7 QWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRASKKPK
:::::: :.:::::::::.:::: ::::::: : . : :..: ..::::. .. : .
NP_862 QWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEAAVLVEDLTQVLDK-R
80 90 100 110 120 130
140 150 160 170 180
pF1KB7 QWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPA-----EPSQAGAYDRL
: .. . :.:::.: :. .: . . :: :: .. . :
NP_862 GWDP---GAEPTEASCKQSDLGESE-PSNVTETLMGGVSLG-PAFVKACEPEGSSERSGL
140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSKGNGLQNP
: . : :: : : .: : :. : .. .: . .:.:..... :
NP_862 SGEIWTKSVTQQIHFKKTSG---PY-----KDVPTDQ--RGRES---GASRNSSSAWPNL
190 200 210 220 230
250 260 270 280 290
pF1KB7 EPRGANMSEPRLSRRQVSSPNAQKPFAHYQ------RHCRVEYIS-SPLKSHPLRELKK-
. :: ... :.. ... :... :.:: . : : :..: . .:
NP_862 TSQEKPPSEDKFD--LVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 ----SKGGKRSLSNRLQHLG-HQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPY
:. :: ..: : ::. :: .... ::..: .:::.:. ..: .:.:.::::.::
NP_862 PYACSECGK-AFS-RSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPY
300 310 320 330 340 350
360 370 380 390 400
pF1KB7 TCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
:::::. :.:.. : :::.::::.::.: :::.: ::..: ::.:.: :.
NP_862 KCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDA
360 370 380 390 400 410
NP_862 CGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKA
420 430 440 450 460 470
>--
initn: 666 init1: 356 opt: 356 Z-score: 233.4 bits: 52.4 E(85289): 2.9e-06
Smith-Waterman score: 356; 56.8% identity (77.8% similar) in 81 aa overlap (324-404:406-486)
300 310 320 330 340 350
pF1KB7 LRELKKSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERP
:::::: ::..:. : : :: :.:.::.:
NP_862 GERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKP
380 390 400 410 420 430
360 370 380 390 400
pF1KB7 YTCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
: : : . :...:.: :::::::::::.:..:::.: .:: : : :.:
NP_862 YQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ
440 450 460 470 480 490
>>XP_006723255 (OMIM: 165260) PREDICTED: zinc finger and (491 aa)
initn: 2652 init1: 412 opt: 744 Z-score: 462.1 bits: 94.7 E(85289): 5.3e-19
Smith-Waterman score: 746; 38.4% identity (62.7% similar) in 383 aa overlap (43-407:46-405)
20 30 40 50 60 70
pF1KB7 TEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGPQEALSQLRQLCR
: : ::.: :.:.:::.:::..:: ::
XP_006 DSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEASGPHEALAHLRALCC
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB7 QWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRASKKPK
:::::: :.:::::::::.:::: ::::::: : . : :..: ..::::. .. : .
XP_006 QWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEAAVLVEDLTQVLDK-R
80 90 100 110 120 130
140 150 160 170 180
pF1KB7 QWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPA-----EPSQAGAYDRL
: .. . :.:::.: :. .: . . :: :: .. . :
XP_006 GWDP---GAEPTEASCKQSDLGESE-PSNVTETLMGGVSLG-PAFVKACEPEGSSERSGL
140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSKGNGLQNP
: . : :: : : .: : :. : .. .: . .:.:..... :
XP_006 SGEIWTKSVTQQIHFKKTSG---PY-----KDVPTDQ--RGRES---GASRNSSSAWPNL
190 200 210 220 230
250 260 270 280 290
pF1KB7 EPRGANMSEPRLSRRQVSSPNAQKPFAHYQ------RHCRVEYIS-SPLKSHPLRELKK-
. :: ... :.. ... :... :.:: . : : :..: . .:
XP_006 TSQEKPPSEDKFD--LVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 ----SKGGKRSLSNRLQHLG-HQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPY
:. :: ..: : ::. :: .... ::..: .:::.:. ..: .:.:.::::.::
XP_006 PYACSECGK-AFS-RSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPY
300 310 320 330 340 350
360 370 380 390 400
pF1KB7 TCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
:::::. :.:.. : :::.::::.::.: :::.: ::..: ::.:.: :.
XP_006 KCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDA
360 370 380 390 400 410
XP_006 CGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKA
420 430 440 450 460 470
>--
initn: 666 init1: 356 opt: 356 Z-score: 233.4 bits: 52.4 E(85289): 2.9e-06
Smith-Waterman score: 356; 56.8% identity (77.8% similar) in 81 aa overlap (324-404:406-486)
300 310 320 330 340 350
pF1KB7 LRELKKSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERP
:::::: ::..:. : : :: :.:.::.:
XP_006 GERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKP
380 390 400 410 420 430
360 370 380 390 400
pF1KB7 YTCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
: : : . :...:.: :::::::::::.:..:::.: .:: : : :.:
XP_006 YQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ
440 450 460 470 480 490
>>NP_112161 (OMIM: 610794) zinc finger and SCAN domain-c (406 aa)
initn: 2113 init1: 391 opt: 730 Z-score: 454.7 bits: 93.1 E(85289): 1.4e-18
Smith-Waterman score: 736; 38.3% identity (61.7% similar) in 371 aa overlap (38-407:31-376)
10 20 30 40 50 60
pF1KB7 TLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGPQEALSQL
: : :: ::.:::::. ::.::::.:
NP_112 MASTEEQYDLKIVKVEEDPIWDQETHLRGNNFSGQEASRQLFRQFCYQETPGPREALSRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRA
:.::.:::.::.:::::::::::.:::::::: :.:: ::.. : :..: :..:::...
NP_112 RELCHQWLRPEIHTKEQILELLVLEQFLTILPEELQAWVREHHPESGEEAVAVVEDLEQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SKKPKQWVAVCMQGQ-KVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQAGAYDR
..: . . .:. .:::: . .:: :.: : .:: : .
NP_112 LSEPGNQAPDHEHGHSEVLLEDVEHLKVKQEPTDIQLQPMVTQLRYESFC-------LHQ
130 140 150 160 170
190 200 210 220 230 240
pF1KB7 LSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSKGNGLQN
.. . :. : :: . : . . .:.: :.. . .: . ::.
NP_112 FQEQDGESIPENQELASKQEILKEMEHLGDSKL--QRDVSLDSKYRETCKRDSKA-----
180 190 200 210 220
250 260 270 280 290 300
pF1KB7 PEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELKKSKGGKRS
: . :. . : : . : :.. . . . : . : . .: :. . . :
NP_112 -EKQQAHSTGERRHR----CNECGKSFTKSSVLIEHQRIHTGEKPYECEECGKAFSRRSS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 LSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECGNCFGRQ
:.. :. .....:::.: .:::.:. .. : ::.:.::::.:: : ::. : .
NP_112 LNE------HRRSHTGEKPYQCKECGKAFSASNGLTRHRRIHTGEKPYECKVCGKAFLLS
290 300 310 320 330
370 380 390 400
pF1KB7 STLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
: : ::::::::: ::: .:::.: :...: :: :.: :.
NP_112 SCLVQHQRIHTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQCSQCSKLFSKRTLLK
340 350 360 370 380 390
NP_112 KHQKIHTGERP
400
>>XP_011513109 (OMIM: 610794) PREDICTED: zinc finger and (406 aa)
initn: 2113 init1: 391 opt: 730 Z-score: 454.7 bits: 93.1 E(85289): 1.4e-18
Smith-Waterman score: 736; 38.3% identity (61.7% similar) in 371 aa overlap (38-407:31-376)
10 20 30 40 50 60
pF1KB7 TLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGPQEALSQL
: : :: ::.:::::. ::.::::.:
XP_011 MASTEEQYDLKIVKVEEDPIWDQETHLRGNNFSGQEASRQLFRQFCYQETPGPREALSRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRA
:.::.:::.::.:::::::::::.:::::::: :.:: ::.. : :..: :..:::...
XP_011 RELCHQWLRPEIHTKEQILELLVLEQFLTILPEELQAWVREHHPESGEEAVAVVEDLEQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SKKPKQWVAVCMQGQ-KVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQAGAYDR
..: . . .:. .:::: . .:: :.: : .:: : .
XP_011 LSEPGNQAPDHEHGHSEVLLEDVEHLKVKQEPTDIQLQPMVTQLRYESFC-------LHQ
130 140 150 160 170
190 200 210 220 230 240
pF1KB7 LSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSKGNGLQN
.. . :. : :: . : . . .:.: :.. . .: . ::.
XP_011 FQEQDGESIPENQELASKQEILKEMEHLGDSKL--QRDVSLDSKYRETCKRDSKA-----
180 190 200 210 220
250 260 270 280 290 300
pF1KB7 PEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELKKSKGGKRS
: . :. . : : . : :.. . . . : . : . .: :. . . :
XP_011 -EKQQAHSTGERRHR----CNECGKSFTKSSVLIEHQRIHTGEKPYECEECGKAFSRRSS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 LSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECGNCFGRQ
:.. :. .....:::.: .:::.:. .. : ::.:.::::.:: : ::. : .
XP_011 LNE------HRRSHTGEKPYQCKECGKAFSASNGLTRHRRIHTGEKPYECKVCGKAFLLS
290 300 310 320 330
370 380 390 400
pF1KB7 STLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
: : ::::::::: ::: .:::.: :...: :: :.: :.
XP_011 SCLVQHQRIHTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQCSQCSKLFSKRTLLK
340 350 360 370 380 390
XP_011 KHQKIHTGERP
400
>>XP_011513110 (OMIM: 610794) PREDICTED: zinc finger and (406 aa)
initn: 2113 init1: 391 opt: 730 Z-score: 454.7 bits: 93.1 E(85289): 1.4e-18
Smith-Waterman score: 736; 38.3% identity (61.7% similar) in 371 aa overlap (38-407:31-376)
10 20 30 40 50 60
pF1KB7 TLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGPQEALSQL
: : :: ::.:::::. ::.::::.:
XP_011 MASTEEQYDLKIVKVEEDPIWDQETHLRGNNFSGQEASRQLFRQFCYQETPGPREALSRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRA
:.::.:::.::.:::::::::::.:::::::: :.:: ::.. : :..: :..:::...
XP_011 RELCHQWLRPEIHTKEQILELLVLEQFLTILPEELQAWVREHHPESGEEAVAVVEDLEQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SKKPKQWVAVCMQGQ-KVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQAGAYDR
..: . . .:. .:::: . .:: :.: : .:: : .
XP_011 LSEPGNQAPDHEHGHSEVLLEDVEHLKVKQEPTDIQLQPMVTQLRYESFC-------LHQ
130 140 150 160 170
190 200 210 220 230 240
pF1KB7 LSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSKGNGLQN
.. . :. : :: . : . . .:.: :.. . .: . ::.
XP_011 FQEQDGESIPENQELASKQEILKEMEHLGDSKL--QRDVSLDSKYRETCKRDSKA-----
180 190 200 210 220
250 260 270 280 290 300
pF1KB7 PEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELKKSKGGKRS
: . :. . : : . : :.. . . . : . : . .: :. . . :
XP_011 -EKQQAHSTGERRHR----CNECGKSFTKSSVLIEHQRIHTGEKPYECEECGKAFSRRSS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 LSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECGNCFGRQ
:.. :. .....:::.: .:::.:. .. : ::.:.::::.:: : ::. : .
XP_011 LNE------HRRSHTGEKPYQCKECGKAFSASNGLTRHRRIHTGEKPYECKVCGKAFLLS
290 300 310 320 330
370 380 390 400
pF1KB7 STLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
: : ::::::::: ::: .:::.: :...: :: :.: :.
XP_011 SCLVQHQRIHTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQCSQCSKLFSKRTLLK
340 350 360 370 380 390
XP_011 KHQKIHTGERP
400
407 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:19:21 2016 done: Sat Nov 5 10:19:23 2016
Total Scan time: 10.040 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]