FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7969, 285 aa 1>>>pF1KB7969 285 - 285 aa - 285 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1263+/-0.000884; mu= 15.3980+/- 0.053 mean_var=55.0442+/-10.987, 0's: 0 Z-trim(104.6): 20 B-trim: 2 in 1/51 Lambda= 0.172869 statistics sampled from 7973 (7982) to 7973 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.245), width: 16 Scan time: 2.330 The best scores are: opt bits E(32554) CCDS6000.2 CNOT7 gene_id:29883|Hs108|chr8 ( 285) 1920 486.9 6.9e-138 CCDS55202.1 CNOT7 gene_id:29883|Hs108|chr8 ( 244) 1630 414.6 3.5e-116 CCDS4329.1 CNOT8 gene_id:9337|Hs108|chr5 ( 292) 1500 382.2 2.4e-106 CCDS78074.1 CNOT8 gene_id:9337|Hs108|chr5 ( 186) 904 233.5 8.9e-62 CCDS75361.1 CNOT8 gene_id:9337|Hs108|chr5 ( 238) 624 163.7 1.2e-40 CCDS78075.1 CNOT8 gene_id:9337|Hs108|chr5 ( 128) 574 151.1 3.8e-37 >>CCDS6000.2 CNOT7 gene_id:29883|Hs108|chr8 (285 aa) initn: 1920 init1: 1920 opt: 1920 Z-score: 2589.0 bits: 486.9 E(32554): 6.9e-138 Smith-Waterman score: 1920; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285) 10 20 30 40 50 60 pF1KB7 MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 190 200 210 220 230 240 250 260 270 280 pF1KB7 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS ::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS 250 260 270 280 >>CCDS55202.1 CNOT7 gene_id:29883|Hs108|chr8 (244 aa) initn: 1686 init1: 1630 opt: 1630 Z-score: 2199.2 bits: 414.6 E(32554): 3.5e-116 Smith-Waterman score: 1630; 99.6% identity (100.0% similar) in 244 aa overlap (1-244:1-244) 10 20 30 40 50 60 pF1KB7 MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 190 200 210 220 230 240 250 260 270 280 pF1KB7 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS :::. CCDS55 MREV >>CCDS4329.1 CNOT8 gene_id:9337|Hs108|chr5 (292 aa) initn: 1498 init1: 1498 opt: 1500 Z-score: 2022.8 bits: 382.2 E(32554): 2.4e-106 Smith-Waterman score: 1500; 76.8% identity (92.1% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KB7 MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY :::: :..:: :::::: ::.:::.:::... .:.:.::::::::::.::::::::. :: CCDS43 MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG ::::::::::::::::::::: ::.:::: : .:::::::::::::::.::::.::..:: CCDS43 QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD .::.:::::::.: .:::::::::::::..::::::::::::::..:.::.: ::::: . CCDS43 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK ::.:: :::: ::::::::::::::::::::::.::.:.::: ::::::::::::::::. CCDS43 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 190 200 210 220 230 240 250 260 270 280 pF1KB7 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS :.:.:::: ::::::::.:::::.: . :: .. .:. CCDS43 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 250 260 270 280 290 >>CCDS78074.1 CNOT8 gene_id:9337|Hs108|chr5 (186 aa) initn: 902 init1: 902 opt: 904 Z-score: 1222.6 bits: 233.5 E(32554): 8.9e-62 Smith-Waterman score: 904; 75.3% identity (92.0% similar) in 174 aa overlap (107-280:1-174) 80 90 100 110 120 130 pF1KB7 LGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSGIQFKKHEEEGIETQYF ::.::::.::..::.::.:::::::.: .: CCDS78 MYSQDSIDLLANSGLQFQKHEEEGIDTLHF 10 20 30 140 150 160 170 180 190 pF1KB7 AELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVK ::::::::::::..::::::::::::::..:.::.: ::::: .::.:: :::: ::::: CCDS78 AELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVK 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB7 YLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFEDHIDDAKYC :::::::::::::::::.::.:.::: ::::::::::::::::.:.:.:::: ::::::: CCDS78 YLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYC 100 110 120 130 140 150 260 270 280 pF1KB7 GHLYGLGSGSSYVQNGTGNAYEEEANKQS :.:::::.: . :: .. .:. CCDS78 GRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 160 170 180 >>CCDS75361.1 CNOT8 gene_id:9337|Hs108|chr5 (238 aa) initn: 648 init1: 622 opt: 624 Z-score: 843.5 bits: 163.7 E(32554): 1.2e-40 Smith-Waterman score: 1086; 61.4% identity (73.2% similar) in 280 aa overlap (1-280:1-226) 10 20 30 40 50 60 pF1KB7 MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY :::: :..:: :::::: ::.:::.:::... .:.:.::::::::::.::::::::. :: CCDS75 MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG ::::::::::::::::::::: ::.:::: : .::::::::::: CCDS75 QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLT---------------- 70 80 90 100 130 140 150 160 170 180 pF1KB7 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD ::::::..:.::.: ::::: . CCDS75 --------------------------------------GYDFGYMVKLLTDSRLPEEEHE 110 120 190 200 210 220 230 240 pF1KB7 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK ::.:: :::: ::::::::::::::::::::::.::.:.::: ::::::::::::::::. CCDS75 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 130 140 150 160 170 180 250 260 270 280 pF1KB7 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS :.:.:::: ::::::::.:::::.: . :: .. .:. CCDS75 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 190 200 210 220 230 >>CCDS78075.1 CNOT8 gene_id:9337|Hs108|chr5 (128 aa) initn: 586 init1: 572 opt: 574 Z-score: 780.4 bits: 151.1 E(32554): 3.8e-37 Smith-Waterman score: 574; 72.4% identity (88.8% similar) in 116 aa overlap (165-280:1-116) 140 150 160 170 180 190 pF1KB7 YFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYD ..:.::.: ::::: .::.:: :::: ::: CCDS78 MVKLLTDSRLPEEEHEFFHILNLFFPSIYD 10 20 30 200 210 220 230 240 250 pF1KB7 VKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFEDHIDDAK :::::::::::::::::::.::.:.::: ::::::::::::::::.:.:.:::: ::::: CCDS78 VKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAK 40 50 60 70 80 90 260 270 280 pF1KB7 YCGHLYGLGSGSSYVQNGTGNAYEEEANKQS :::.:::::.: . :: .. .:. CCDS78 YCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 100 110 120 285 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:19:59 2016 done: Sat Nov 5 10:20:00 2016 Total Scan time: 2.330 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]