Result of FASTA (omim) for
pF1KB7979
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7979, 432 aa
1>>>pF1KB7979 432 - 432 aa - 432 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3273+/-0.00046; mu= 11.1131+/- 0.028
mean_var=85.5860+/-17.132, 0's: 0 Z-trim(109.5): 104 B-trim: 0 in 0/53
Lambda= 0.138635
statistics sampled from 17658 (17740) to 17658 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.557), E-opt: 0.2 (0.208), width: 16
Scan time: 8.890
The best scores are: opt bits E(85289)
XP_011512465 (OMIM: 604507) PREDICTED: pachytene c ( 432) 2765 563.7 3.2e-160
NP_004228 (OMIM: 604507) pachytene checkpoint prot ( 432) 2765 563.7 3.2e-160
NP_001159732 (OMIM: 604507) pachytene checkpoint p ( 289) 1874 385.4 9.9e-107
NP_006169 (OMIM: 601633) vesicle-fusing ATPase [Ho ( 744) 219 54.6 1e-06
XP_006722645 (OMIM: 609983) PREDICTED: vacuolar pr ( 326) 151 40.9 0.006
XP_011524570 (OMIM: 609983) PREDICTED: vacuolar pr ( 418) 151 40.9 0.0075
NP_004860 (OMIM: 609983) vacuolar protein sorting- ( 444) 151 40.9 0.0079
>>XP_011512465 (OMIM: 604507) PREDICTED: pachytene check (432 aa)
initn: 2765 init1: 2765 opt: 2765 Z-score: 2997.5 bits: 563.7 E(85289): 3.2e-160
Smith-Waterman score: 2765; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432)
10 20 30 40 50 60
pF1KB7 MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 FIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDK
370 380 390 400 410 420
430
pF1KB7 QFEERKKLAAYI
::::::::::::
XP_011 QFEERKKLAAYI
430
>>NP_004228 (OMIM: 604507) pachytene checkpoint protein (432 aa)
initn: 2765 init1: 2765 opt: 2765 Z-score: 2997.5 bits: 563.7 E(85289): 3.2e-160
Smith-Waterman score: 2765; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432)
10 20 30 40 50 60
pF1KB7 MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 FIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDK
370 380 390 400 410 420
430
pF1KB7 QFEERKKLAAYI
::::::::::::
NP_004 QFEERKKLAAYI
430
>>NP_001159732 (OMIM: 604507) pachytene checkpoint prote (289 aa)
initn: 1874 init1: 1874 opt: 1874 Z-score: 2037.1 bits: 385.4 E(85289): 9.9e-107
Smith-Waterman score: 1874; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289)
10 20 30 40 50 60
pF1KB7 MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSN
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKR
250 260 270 280
310 320 330 340 350 360
pF1KB7 ITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIG
>>NP_006169 (OMIM: 601633) vesicle-fusing ATPase [Homo s (744 aa)
initn: 144 init1: 82 opt: 219 Z-score: 241.7 bits: 54.6 E(85289): 1e-06
Smith-Waterman score: 219; 22.0% identity (55.7% similar) in 341 aa overlap (10-330:87-406)
10 20 30
pF1KB7 MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDIN
.: :.. . :.... :. : .. : .
NP_006 PGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIG-TMTIEIDFLQKKSIDSNPYDTD
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB7 LSVRKLLNRHN---IVFGDYTWTEFDEPF---LTRNVQSV--SIIDTELKVKDSQPIDLS
. ..... : . :. :.: . :....... ::. : . : :...
NP_006 KMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVG
120 130 140 150 160 170
100 110 120 130 140
pF1KB7 ACTVALHI-FQLNEDGPSSENL------EEETENIIAANHWVLPAAEFHGLWDSLVYDVE
. .. :. :. :: :: .:. ..:: . : . . :: : :
NP_006 LVVGNSQVAFEKAEN--SSLNLIGKAKTKENRQSIINPD-WNFEKMGIGGL------DKE
180 190 200 210 220
150 160 170 180 190 200
pF1KB7 VKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRY
: .. .... .: . :.. . .::.:::: ::: : . ... :. : .
NP_006 F-SDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKV-
230 240 250 260 270 280
210 220 230 240 250 260
pF1KB7 RYGQLIEINSHSLFSKWFSESGKLVTKMF---QKIQDLIDDKDALVFVLIDEVESLTAAR
.:. ...:. .:: . :.: .. : . ...: ....::.... :
NP_006 -------VNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR
290 300 310 320 330
270 280 290 300 310
pF1KB7 NACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFV--DRADIKQYI
.. ..: :. ::: .:..:: ... .:.... .: . :: :.. : ..:. :
NP_006 GSMAGSTGVHDT--VVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEI
340 350 360 370 380 390
320 330 340 350 360 370
pF1KB7 GPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLNDISRK
: :. . ..:
NP_006 GLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNR
400 410 420 430 440 450
>>XP_006722645 (OMIM: 609983) PREDICTED: vacuolar protei (326 aa)
initn: 230 init1: 85 opt: 151 Z-score: 173.9 bits: 40.9 E(85289): 0.006
Smith-Waterman score: 239; 33.7% identity (62.0% similar) in 166 aa overlap (171-332:49-196)
150 160 170 180 190 200
pF1KB7 YDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRL
: : .:: :::::::. : ::.: . .
XP_006 AGLEGAKEALKEAVILPIKFPHLFTGKRTPW-RGILLFGPPGTGKSYLAKAVATEAN---
20 30 40 50 60 70
210 220 230 240 250 260
pF1KB7 SSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAA
.: . . :.: .: :::..:: ::: ..:: . ..: ...: :::..:: ..
XP_006 NSTF-----FSISSSDLVSKWLGESEKLVKNLFQLAR---ENKPSIIF--IDEIDSLCGS
80 90 100 110 120
270 280 290 300 310
pF1KB7 RNACRAGTEPSDAIRVVNAVLTQIDQIKRHSN-VVILTTSNITEKIDVAFVDRADIKQYI
:. .: : :. . :.:.. . .. ...: ..:: .: :. : . . ::
XP_006 RSE----NESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYI
130 140 150 160 170 180
320 330 340 350 360 370
pF1KB7 G---PPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLNDI
: . ::.::..:
XP_006 PLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPVRKVQS
190 200 210 220 230 240
>>XP_011524570 (OMIM: 609983) PREDICTED: vacuolar protei (418 aa)
initn: 182 init1: 85 opt: 151 Z-score: 172.2 bits: 40.9 E(85289): 0.0075
Smith-Waterman score: 242; 28.0% identity (59.1% similar) in 232 aa overlap (105-332:109-314)
80 90 100 110 120 130
pF1KB7 IIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENIIAANHWVLPAAEFHG
: : ...:... .. :. .. : ..
XP_011 KEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPEKKKLQNQLQGAIVIER---PNVK---
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB7 LWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQ
:.... .: : . :. . : . ... : : .:: :::::::. : ::.:
XP_011 -WSDVAGLEGAKEALKEAVILPIKFP-HLFTGKRTPW-RGILLFGPPGTGKSYLAKAVA-
140 150 160 170 180
200 210 220 230 240 250
pF1KB7 KLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEV
.. . .. :.: .: :::..:: ::: ..:: .. .: ...: :::.
XP_011 -------TEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARE---NKPSIIF--IDEI
190 200 210 220 230
260 270 280 290 300 310
pF1KB7 ESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSN-VVILTTSNITEKIDVAFVDRA
.:: ..:. .: : :. . :.:.. . .. ...: ..:: .: :. :
XP_011 DSLCGSRSE----NESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRF
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB7 DIKQYIG---PPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLS
. . :: : . ::.::..:
XP_011 EKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQP
300 310 320 330 340 350
>>NP_004860 (OMIM: 609983) vacuolar protein sorting-asso (444 aa)
initn: 182 init1: 85 opt: 151 Z-score: 171.8 bits: 40.9 E(85289): 0.0079
Smith-Waterman score: 242; 28.0% identity (59.1% similar) in 232 aa overlap (105-332:109-314)
80 90 100 110 120 130
pF1KB7 IIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENIIAANHWVLPAAEFHG
: : ...:... .. :. .. : ..
NP_004 KEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPEKKKLQNQLQGAIVIER---PNVK---
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB7 LWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQ
:.... .: : . :. . : . ... : : .:: :::::::. : ::.:
NP_004 -WSDVAGLEGAKEALKEAVILPIKFP-HLFTGKRTPW-RGILLFGPPGTGKSYLAKAVA-
140 150 160 170 180
200 210 220 230 240 250
pF1KB7 KLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEV
.. . .. :.: .: :::..:: ::: ..:: .. .: ...: :::.
NP_004 -------TEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARE---NKPSIIF--IDEI
190 200 210 220 230
260 270 280 290 300 310
pF1KB7 ESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSN-VVILTTSNITEKIDVAFVDRA
.:: ..:. .: : :. . :.:.. . .. ...: ..:: .: :. :
NP_004 DSLCGSRSE----NESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRF
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB7 DIKQYIG---PPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLS
. . :: : . ::.::..:
NP_004 EKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQP
300 310 320 330 340 350
432 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:21:50 2016 done: Sat Nov 5 10:21:52 2016
Total Scan time: 8.890 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]