Result of FASTA (omim) for
pF1KB7988
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7988, 325 aa
1>>>pF1KB7988 325 - 325 aa - 325 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3603+/-0.000317; mu= 10.2912+/- 0.020
mean_var=215.7156+/-44.049, 0's: 0 Z-trim(123.3): 296 B-trim: 100 in 1/60
Lambda= 0.087324
statistics sampled from 42637 (42965) to 42637 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.504), width: 16
Scan time: 9.380
The best scores are: opt bits E(85289)
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 2206 289.8 5.3e-78
NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 416 64.5 5.8e-10
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 387 60.5 4.7e-09
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 368 58.2 2.8e-08
NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314) 359 57.1 5.8e-08
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 355 56.8 1.1e-07
NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 355 56.8 1.1e-07
NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 355 56.8 1.1e-07
NP_000316 (OMIM: 137600,180500,180550,601542,60422 ( 324) 351 56.1 1.2e-07
XP_016883326 (OMIM: 122000,148300,605020,614195) P ( 280) 346 55.4 1.7e-07
NP_001243201 (OMIM: 122000,148300,605020,614195) v ( 301) 346 55.4 1.8e-07
NP_055403 (OMIM: 122000,148300,605020,614195) visu ( 365) 346 55.5 2e-07
NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406) 344 55.3 2.5e-07
NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354) 342 55.0 2.8e-07
NP_001186699 (OMIM: 600036) homeobox protein OTX1 ( 354) 342 55.0 2.8e-07
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 338 54.6 4.8e-07
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 338 54.6 4.8e-07
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 338 54.6 4.8e-07
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 338 54.7 4.9e-07
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317) 333 53.8 5.6e-07
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317) 333 53.8 5.6e-07
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317) 333 53.8 5.6e-07
NP_001157150 (OMIM: 602504) short stature homeobox ( 319) 333 53.8 5.7e-07
NP_006875 (OMIM: 602504) short stature homeobox pr ( 331) 333 53.8 5.8e-07
NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 330 53.2 6e-07
NP_700476 (OMIM: 137600,180500,180550,601542,60422 ( 271) 331 53.5 6.1e-07
NP_001191328 (OMIM: 137600,180500,180550,601542,60 ( 271) 331 53.5 6.1e-07
XP_011530329 (OMIM: 137600,180500,180550,601542,60 ( 271) 331 53.5 6.1e-07
NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184) 327 52.8 6.7e-07
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 332 53.8 7.3e-07
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302) 329 53.3 7.8e-07
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 327 52.9 8.4e-07
NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 326 52.8 9e-07
NP_006252 (OMIM: 262600,601538) homeobox protein p ( 226) 323 52.4 1.1e-06
NP_878314 (OMIM: 142993,610092,610093) visual syst ( 361) 326 53.0 1.1e-06
XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 320 52.0 1.4e-06
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 322 52.4 1.5e-06
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 322 52.5 1.7e-06
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 322 52.5 1.7e-06
NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326) 320 52.2 1.8e-06
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 314 51.1 2.2e-06
NP_001290437 (OMIM: 612019) intestine-specific hom ( 245) 315 51.4 2.3e-06
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 311 51.1 4.1e-06
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 302 50.0 9.8e-06
XP_006713790 (OMIM: 602504) PREDICTED: short statu ( 343) 300 49.7 1.1e-05
NP_003021 (OMIM: 602504) short stature homeobox pr ( 355) 300 49.7 1.1e-05
NP_008833 (OMIM: 167420,202650) paired mesoderm ho ( 217) 296 48.9 1.1e-05
NP_073207 (OMIM: 167420,202650) paired mesoderm ho ( 245) 296 49.0 1.2e-05
XP_016862544 (OMIM: 602504) PREDICTED: short statu ( 190) 293 48.5 1.3e-05
XP_006713791 (OMIM: 602504) PREDICTED: short statu ( 190) 293 48.5 1.3e-05
>>NP_115485 (OMIM: 604529) homeobox protein orthopedia [ (325 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 1521.3 bits: 289.8 E(85289): 5.3e-78
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KB7 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSSPDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSSPDSS
250 260 270 280 290 300
310 320
pF1KB7 DVWRGTSIASLRRKALEHTVSMSFT
:::::::::::::::::::::::::
NP_115 DVWRGTSIASLRRKALEHTVSMSFT
310 320
>>NP_620689 (OMIM: 300004,300215,300382,300419,308350,30 (562 aa)
initn: 434 init1: 399 opt: 416 Z-score: 299.8 bits: 64.5 E(85289): 5.8e-10
Smith-Waterman score: 443; 35.4% identity (56.5% similar) in 333 aa overlap (16-323:255-547)
10 20 30 40
pF1KB7 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDL
:: :: .: .: ... :. .. . .
NP_620 DDEEELLEDEEDEDEEEELLEDDEEELLEDDARALL--KEPRRCPVAATGAVAAAAAAAV
230 240 250 260 270 280
50 60 70 80 90 100
pF1KB7 APNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQG--QQK
: .::. : : :. : . .: . . : .. . . ...: ..:
NP_620 A-----TEGGELSPKEE----------LLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRK
290 300 310 320
110 120 130 140 150 160
pF1KB7 QKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRK
:.:.:: :: ::.::::.: ::::::.: :::::.:. :::.:::::::::::::.::.
NP_620 QRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKRE
330 340 350 360 370 380
170 180 190 200 210 220
pF1KB7 KTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFH--ANDTRWAAAAMPGVSQLP
:. . :: :: :: : ::. . . : : : :. :.::: ... .:
NP_620 KAGAQTHPPG--LPFPG-PL--SATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFP
390 400 410 420 430 440
230 240 250 260 270
pF1KB7 -LPPALGRQQAMAQSLSQCSLAAGPPPNS-MGLSNSLAGSNGAGLQSH--LYQPAF----
::: : :. :: .. .:::. : ::.. : . .:::
NP_620 SLPPPPGS-------------ASLPPSGAPLGLSTFL----GAAVFRHPAFISPAFGRLF
450 460 470 480
280 290 300 310 320
pF1KB7 PGMVP-------ASL---PGPSNVSG---SPQLCSSPDSSDVWRGTSIASLRRKALEHTV
:.: :.: : :. : : : : . .. :..:::.:: :: ::..
NP_620 STMAPLTSASTAAALLRQPTPA-VEGAVASGALADPATAAADRRASSIAALRLKAKEHAA
490 500 510 520 530 540
pF1KB7 SMSFT
...
NP_620 QLTQLNILPGTSTGKEVC
550 560
>>NP_005160 (OMIM: 602078,602753) paired mesoderm homeob (284 aa)
initn: 362 init1: 304 opt: 387 Z-score: 283.5 bits: 60.5 E(85289): 4.7e-09
Smith-Waterman score: 415; 36.7% identity (60.0% similar) in 270 aa overlap (36-284:28-263)
10 20 30 40 50 60
pF1KB7 DLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITT
:.::: . .:.. : : .
NP_005 MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGF------QYSPLRPAFPAAGPPCPA
10 20 30 40 50
70 80 90 100 110
pF1KB7 VGSTPASLAVSAKDPDKQPGPQGG------PNPSQAGQQQGQQKQKRHRTRFTPAQLNEL
.::. .:.. :.::.: .. :.:: : .. ..::.: :: :: :::.::
NP_005 LGSSNCALGALR---DHQPAPYSAVPYKFFPEPS--GLHE-KRKQRRIRTTFTSAQLKEL
60 70 80 90 100
120 130 140 150 160 170
pF1KB7 ERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTP
:: ::.::::::. ::::::.: :::.::::::::::::..:...... : :
NP_005 ERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAAS---AKG------
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 GLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAA-MP-GVSQLPLPPALGRQQA-MAQSL
::.::.: :.. :: . .:.. .. . : ....:: ::: : . .. :
NP_005 -------AAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSP
160 170 180 190 200
240 250 260 270 280
pF1KB7 SQCSLAAGPPPNS----------MGLSNSLAGSNGAGLQSHL--YQPAFPGMVPASLPGP
.:..:: :. :.... .:. ::: : .::: : :::
NP_005 LPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAAELLKAWQPAESG------PGP
210 220 230 240 250 260
290 300 310 320
pF1KB7 SNVSGSPQLCSSPDSSDVWRGTSIASLRRKALEHTVSMSFT
NP_005 FSGVLSSFHRKPGPALKTNLF
270 280
>>NP_038463 (OMIM: 601881,611038) retinal homeobox prote (346 aa)
initn: 399 init1: 302 opt: 368 Z-score: 269.6 bits: 58.2 E(85289): 2.8e-08
Smith-Waterman score: 423; 34.3% identity (54.2% similar) in 321 aa overlap (8-318:35-335)
10 20 30
pF1KB7 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSD
..: ::. .:: : . :. :
NP_038 GCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGTFPAERGARGAKERD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 P--GGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDK---QPGPQGGPNP
:..:. :.. : ::. : . . : :.: . .:: ::
NP_038 RRLGARPA--CPKA-PEEGSEPSPPPAPAPAPEYEAPRPYCPKEPGEARPSPGLPVGPAT
70 80 90 100 110 120
100 110 120 130 140
pF1KB7 SQAG---QQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQ
..: ..: ..:..:.:: :: ::.::::.: :.::::.. ::::: ...: : :::
NP_038 GEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQ
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB7 VWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRW
::::::::::....: . : .: : : .:. . .: . : .
NP_038 VWFQNRRAKWRRQEKLEV---SSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGP----
190 200 210 220 230
210 220 230 240 250 260
pF1KB7 AAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLY
:..:.: : : :: : . ::: . ::: .:. : . :.:
NP_038 AGGALPLESWLG-PPLPGGGATALQSLP----GFGPPAQSLPASYTPPPPPPPFLNS---
240 250 260 270 280
270 280 290 300 310 320
pF1KB7 QPAFPGMVPASLPGPSNVSGSPQLCSS-P-DSSDVWRGTSIASLRRKALEHTVSMSFT
: ::. : . : :: : : . .. : : .: :..:::.:: :: ::
NP_038 PPLGPGLQPLAPPPPSYPCG-PGFGDKFPLDEADP-RNSSIAALRLKAKEHIQAIGKPWQ
290 300 310 320 330 340
NP_038 AL
>>NP_002644 (OMIM: 119800,186550,602149) pituitary homeo (314 aa)
initn: 320 init1: 285 opt: 359 Z-score: 264.0 bits: 57.1 E(85289): 5.8e-08
Smith-Waterman score: 385; 32.6% identity (56.1% similar) in 310 aa overlap (30-319:12-293)
10 20 30 40 50 60
pF1KB7 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPG
:: : : : :..: .. : :
NP_002 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPAD--PR
10 20 30 40
70 80 90 100 110
pF1KB7 EDITTVGSTPASLAVSAKDPDKQP-GPQ----GGPNPSQAGQQQGQQKQKRHRTRFTPAQ
: . . .: .. . :. .: ::. :: . . : . ..::.:.::.:: :
NP_002 EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 LNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTL
:.::: .: ...:::. ::::.:. .::: ::.:::.::::::.::... .. :
NP_002 LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGY
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 LPT-PGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPP-ALGRQQAMA
.: :: : : . ::. . :. ::: .. . :: .. ..:.
NP_002 VPQFSGLVQ-PYEDVYAAG--------YSYNN--WAAKSL---APAPLSTKSFTFFNSMS
170 180 190 200
240 250 260 270 280 290
pF1KB7 QSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGS---
:: ..: :.:.. : .. .: : : : ::: ..: . .:..::
NP_002 PLSSQSMFSA---PSSIS-SMTMPSSMGPG--------AVPGMPNSGLNNINNLTGSSLN
210 220 230 240 250
300 310 320
pF1KB7 ----PQLC--SSPDSS-DVWRGT---SIASLRRKALEHTVSMSFT
: : ..: : .:.: : :.:::: :. .:.
NP_002 SAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS
260 270 280 290 300 310
>>NP_001128726 (OMIM: 167410,268220) paired box protein (505 aa)
initn: 352 init1: 288 opt: 355 Z-score: 258.9 bits: 56.8 E(85289): 1.1e-07
Smith-Waterman score: 355; 36.4% identity (59.3% similar) in 231 aa overlap (101-315:214-427)
80 90 100 110 120 130
pF1KB7 ASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPD
..::.: :: :: ::.:::..: .:::::
NP_001 AKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPD
190 200 210 220 230 240
140 150 160 170 180
pF1KB7 IFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNV--FRA--PGTLLPT--PGLP--
:. ::::: : :::.::::::.::::.:.:. .... : :: . :: : ::
NP_001 IYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPY
250 260 270 280 290 300
190 200 210 220 230 240
pF1KB7 QFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQ--AMAQSLSQCS
:.:... ... :. . : . ::::. .: : : . .. :
NP_001 QLPDSTYPTTTISQDGGSTVHRPQ--------------PLPPSTMHQGGLAAAAAAADTS
310 320 330 340
250 260 270 280 290
pF1KB7 LAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVP---ASLPGPSNVSGSPQ--LCS
: : . . :.:. : :. ..:. .:. :. : . : .:: : .:: .
NP_001 SAYGARHSFSSYSDSFM--NPAAPSNHM-NPVSNGLSPQVMSILGNPSAVPPQPQADFSI
350 360 370 380 390 400
300 310 320
pF1KB7 SPDSSDVWRGTSI-ASLRRKALEHTVSMSFT
:: . . .::: :: ..:
NP_001 SPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYG
410 420 430 440 450 460
>>NP_039236 (OMIM: 167410,268220) paired box protein Pax (518 aa)
initn: 352 init1: 288 opt: 355 Z-score: 258.7 bits: 56.8 E(85289): 1.1e-07
Smith-Waterman score: 355; 36.4% identity (59.3% similar) in 231 aa overlap (101-315:212-425)
80 90 100 110 120 130
pF1KB7 ASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPD
..::.: :: :: ::.:::..: .:::::
NP_039 AKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPD
190 200 210 220 230 240
140 150 160 170 180
pF1KB7 IFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNV--FRA--PGTLLPT--PGLP--
:. ::::: : :::.::::::.::::.:.:. .... : :: . :: : ::
NP_039 IYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPY
250 260 270 280 290 300
190 200 210 220 230 240
pF1KB7 QFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQ--AMAQSLSQCS
:.:... ... :. . : . ::::. .: : : . .. :
NP_039 QLPDSTYPTTTISQDGGSTVHRPQ--------------PLPPSTMHQGGLAAAAAAADTS
310 320 330 340
250 260 270 280 290
pF1KB7 LAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVP---ASLPGPSNVSGSPQ--LCS
: : . . :.:. : :. ..:. .:. :. : . : .:: : .:: .
NP_039 SAYGARHSFSSYSDSFM--NPAAPSNHM-NPVSNGLSPQVMSILGNPSAVPPQPQADFSI
350 360 370 380 390 400
300 310 320
pF1KB7 SPDSSDVWRGTSI-ASLRRKALEHTVSMSFT
:: . . .::: :: ..:
NP_039 SPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYG
410 420 430 440 450 460
>>NP_002575 (OMIM: 167410,268220) paired box protein Pax (520 aa)
initn: 352 init1: 288 opt: 355 Z-score: 258.7 bits: 56.8 E(85289): 1.1e-07
Smith-Waterman score: 355; 36.4% identity (59.3% similar) in 231 aa overlap (101-315:214-427)
80 90 100 110 120 130
pF1KB7 ASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPD
..::.: :: :: ::.:::..: .:::::
NP_002 AKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPD
190 200 210 220 230 240
140 150 160 170 180
pF1KB7 IFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNV--FRA--PGTLLPT--PGLP--
:. ::::: : :::.::::::.::::.:.:. .... : :: . :: : ::
NP_002 IYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPY
250 260 270 280 290 300
190 200 210 220 230 240
pF1KB7 QFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQ--AMAQSLSQCS
:.:... ... :. . : . ::::. .: : : . .. :
NP_002 QLPDSTYPTTTISQDGGSTVHRPQ--------------PLPPSTMHQGGLAAAAAAADTS
310 320 330 340
250 260 270 280 290
pF1KB7 LAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVP---ASLPGPSNVSGSPQ--LCS
: : . . :.:. : :. ..:. .:. :. : . : .:: : .:: .
NP_002 SAYGARHSFSSYSDSFM--NPAAPSNHM-NPVSNGLSPQVMSILGNPSAVPPQPQADFSI
350 360 370 380 390 400
300 310 320
pF1KB7 SPDSSDVWRGTSI-ASLRRKALEHTVSMSFT
:: . . .::: :: ..:
NP_002 SPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYG
410 420 430 440 450 460
>>NP_000316 (OMIM: 137600,180500,180550,601542,604229) p (324 aa)
initn: 322 init1: 274 opt: 351 Z-score: 258.4 bits: 56.1 E(85289): 1.2e-07
Smith-Waterman score: 358; 31.2% identity (57.9% similar) in 311 aa overlap (21-319:10-299)
10 20 30 40 50
pF1KB7 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNS--DPVEGATLL
: :: :. .:.. .:. :: :: : : . .:
NP_000 MNCMKGPLHLEHR-AAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLD
10 20 30 40
60 70 80 90 100 110
pF1KB7 PGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQK-QKRHRTRFTPAQLN
.. : . . . : . ::. : : : . .... ...: :.:.::.:: ::.
NP_000 SSKHRLEVHTISDTSSPEAAEKDKS---QQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQ
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 ELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLP
::: .: ...:::. :::.:. .:::.::.:::.::::::.::... .. . . :
NP_000 ELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGP
110 120 130 140 150 160
180 190 200 210 220
pF1KB7 T-PGLPQ-----FPSAAAAAAAAMGDSLCSFHANDTRW--AAAAMPGVSQ-LPLPPALGR
:: : .:. . :: : . :. ... . . . : :: . ::
NP_000 QFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSIS
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB7 QQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVS
...:..:. : ..: : .:.. :.: . .. .:.: . :: : ..: : : :
NP_000 SMSMSSSMVP-SAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACP-YAP---PTPPYVY
230 240 250 260 270 280
290 300 310 320
pF1KB7 GSPQLCSSPDSSDVWRGTSIASLRRKALEHTVSMSFT
. :.: :.:::: :: .:.
NP_000 RD--TCNS----------SLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
290 300 310 320
>>XP_016883326 (OMIM: 122000,148300,605020,614195) PREDI (280 aa)
initn: 276 init1: 276 opt: 346 Z-score: 255.7 bits: 55.4 E(85289): 1.7e-07
Smith-Waterman score: 346; 44.9% identity (70.3% similar) in 118 aa overlap (47-164:110-224)
20 30 40 50 60 70
pF1KB7 AAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVS
: : .: : :.. ..: : .::
XP_016 LGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPLAPSRPPPALGRQKRSDSVS
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB7 AKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREE
..: :.: . : .:. :..:..:::: :: ::.:::..:...::::.. ::
XP_016 TSDEDSQSEDR---NDLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREM
140 150 160 170 180 190
140 150 160 170 180 190
pF1KB7 LALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMG
::.. : :.:.:::::::::::.::.:
XP_016 LAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSA
200 210 220 230 240 250
325 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:27:41 2016 done: Sat Nov 5 16:27:42 2016
Total Scan time: 9.380 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]