FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7990, 326 aa 1>>>pF1KB7990 326 - 326 aa - 326 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6692+/-0.000755; mu= 2.4330+/- 0.046 mean_var=185.8588+/-37.140, 0's: 0 Z-trim(116.5): 39 B-trim: 112 in 1/51 Lambda= 0.094077 statistics sampled from 17068 (17105) to 17068 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.82), E-opt: 0.2 (0.525), width: 16 Scan time: 3.090 The best scores are: opt bits E(32554) CCDS1766.1 FOSL2 gene_id:2355|Hs108|chr2 ( 326) 2146 302.6 2.8e-82 CCDS9841.1 FOS gene_id:2353|Hs108|chr14 ( 380) 630 96.9 2.8e-20 CCDS8121.1 FOSL1 gene_id:8061|Hs108|chr11 ( 271) 487 77.4 1.5e-14 CCDS12664.1 FOSB gene_id:2354|Hs108|chr19 ( 338) 487 77.4 1.8e-14 >>CCDS1766.1 FOSL2 gene_id:2355|Hs108|chr2 (326 aa) initn: 2146 init1: 2146 opt: 2146 Z-score: 1590.6 bits: 302.6 E(32554): 2.8e-82 Smith-Waterman score: 2146; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326) 10 20 30 40 50 60 pF1KB7 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 EFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 EFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 AQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 AQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESC 250 260 270 280 290 300 310 320 pF1KB7 SKAHRRSSSSGDQSSDSLNSPTLLAL :::::::::::::::::::::::::: CCDS17 SKAHRRSSSSGDQSSDSLNSPTLLAL 310 320 >>CCDS9841.1 FOS gene_id:2353|Hs108|chr14 (380 aa) initn: 703 init1: 560 opt: 630 Z-score: 477.6 bits: 96.9 E(32554): 2.8e-20 Smith-Waterman score: 771; 42.4% identity (64.6% similar) in 387 aa overlap (1-317:2-371) 10 20 30 40 pF1KB7 MYQDYPGNFD-TSSRGSSGSPA-------H--AESYSSGGG--GQQKFRVDMPGSGSAF :.. . .... .::: ::.::: : :.:.:: :. . : : .:. :.. : CCDS98 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 IPTINAITTSQDLQWMVQPTVITSMSNPYPRS-HPYSPLPGLASVPGHMALPRPGVIKTI :::..::.:: ::::.:::....:.. :. ::.. .:. :. : : ::.::. CCDS98 IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFG-VPA----PSAGAYSRAGVVKTM 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 ----GTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEE . ..::: . :::::::::::::::::::.:::::::::::::. :::::..::.: CCDS98 TGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDE 120 130 140 150 160 170 170 180 190 200 pF1KB7 KSGLQKEIAELQKEKEKLEFMLVAHGPVCKIS-----PEERR--------------SP-- ::.:: :::.: ::::::::.:.:: :.::: ::: .: CCDS98 KSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPES 180 190 200 210 220 230 210 220 230 240 pF1KB7 -------------PAPGLQPMRSGGGSVGAVVVKQEPLEE-DSPSSSSAGLDKAQRSVIK : :...:..: .... .: ::... :.:: . ... ::: CCDS98 EEAFTLPLLNDPEPKPSVEPVKS----ISSMELKTEPFDDFLFPASSRPSGSETARSV-P 240 250 260 270 280 290 250 260 270 280 pF1KB7 PISIAGGFYGE--EPLHT------PI----------VVTSTPAVTPGTSNLVFTYPSVLE ....:.::. ::::. :. ::: ::. : ::..::::: CCDS98 DMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYP---- 300 310 320 330 340 290 300 310 320 pF1KB7 QESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL :. . :: :. :::..:::.. :::: CCDS98 -EADSFPS--CAAAHRKGSSSNEPSSDSLSSPTLLAL 350 360 370 380 >>CCDS8121.1 FOSL1 gene_id:8061|Hs108|chr11 (271 aa) initn: 546 init1: 413 opt: 487 Z-score: 374.8 bits: 77.4 E(32554): 1.5e-14 Smith-Waterman score: 766; 46.7% identity (65.7% similar) in 332 aa overlap (1-326:1-271) 10 20 30 40 50 pF1KB7 MYQDY--PGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQ :..:. :: .... :. :.::. . ... .::::.. .:.::... :: CCDS81 MFRDFGEPGP-SSGNGGGYGGPAQPPAAAQA--AQQKFHL---------VPSINTMSGSQ 10 20 30 40 60 70 80 90 100 110 pF1KB7 DLQWMVQPTVITSMSNPYPRSHP-YSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRD- .::::::: . : : : ..: ::: : ::::::...: : ::: CCDS81 ELQWMVQPHFLGPSSYPRPLTYPQYSP-------P----QPRPGVIRALGPPPGVRRRPC 50 60 70 80 90 120 130 140 150 160 170 pF1KB7 EQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKE ::.::::::.::.::::::::::::::::.:::. :::::..::.::::::.:: ::::. CCDS81 EQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQ 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 KEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSA ::.::..: :: :.::: :: :.. : :. :.:.. CCDS81 KERLELVLEAHRPICKI-PE----------------GAKEG-----------DTGSTSGT 160 170 180 240 250 260 270 280 290 pF1KB7 GLDKAQRSVIKPISIAGGFYGE-EPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPAS . : . ::.. : : : :::: ..: ::..:: : .::::::: . CCDS81 SSPPAPCRPVPCISLSPGPVLEPEALHTPTLMT-TPSLTPFTPSLVFTYPS--------T 190 200 210 220 230 240 300 310 320 pF1KB7 PSESCSKAHRRSSSS-GDQSSDSLNSPTLLAL : : :..:::.:::: :: ::: :.::::::: CCDS81 P-EPCASAHRKSSSSSGDPSSDPLGSPTLLAL 250 260 270 >>CCDS12664.1 FOSB gene_id:2354|Hs108|chr19 (338 aa) initn: 638 init1: 433 opt: 487 Z-score: 373.4 bits: 77.4 E(32554): 1.8e-14 Smith-Waterman score: 722; 44.0% identity (63.4% similar) in 366 aa overlap (1-326:1-338) 10 20 30 40 50 pF1KB7 MYQDYPGNFDTSSRGSSGSPAHAESYSS---------GGGGQQKFRV-DMPGSGSAFIPT :.: .::..:..:: ::. :... :: ....:. . .:::: :.:: CCDS12 MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGS---FVPT 10 20 30 40 50 60 70 80 90 100 pF1KB7 INAITTSQDLQWMVQPTVITSM---------SNPYPRSHPYSPLPGLA-SVPGHMALPRP ..::::::::::.::::.:.:: :.: : ::. .:: . :.:: . CCDS12 VTAITTSQDLQWLVQPTLISSMAQSQGQPLASQP-PVVDPYD-MPGTSYSTPGMSGYSSG 60 70 80 90 100 110 110 120 130 140 pF1KB7 GVI-----KTIGTTVG-----------RRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNR :. .: ::: : :: :.: :.::::::::.::::::::::::::: CCDS12 GASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNR 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB7 RRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAP :::::..:::::..:::::. :..::::::::::.:::.:::: : ::: :: :.: CCDS12 RRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEE---GPGP 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 G-LQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHT : : .:. ::. : :.. . : : : : : ....... :. CCDS12 GPLAEVRDLPGSAPA---KEDGFSWLLPPPPPPPLP-FQTSQDAPPNLTASLF----THS 240 250 260 270 280 270 280 290 300 310 320 pF1KB7 PIVVTSTP--AVTPG-TSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNS . : . : .:.:. ::..:.: : : . . :.: :.: :: :: ::: CCDS12 EVQVLGDPFPVVNPSYTSSFVLTCPEV----------SAFAGAQRTSGS--DQPSDPLNS 290 300 310 320 330 pF1KB7 PTLLAL :.:::: CCDS12 PSLLAL 326 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:23:00 2016 done: Sat Nov 5 10:23:01 2016 Total Scan time: 3.090 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]