FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7990, 326 aa 1>>>pF1KB7990 326 - 326 aa - 326 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6696+/-0.00032; mu= 2.8715+/- 0.020 mean_var=212.3096+/-41.479, 0's: 0 Z-trim(124.2): 48 B-trim: 0 in 0/59 Lambda= 0.088022 statistics sampled from 45441 (45492) to 45441 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.533), width: 16 Scan time: 8.050 The best scores are: opt bits E(85289) NP_005244 (OMIM: 601575) fos-related antigen 2 [Ho ( 326) 2146 284.2 2.5e-76 XP_016859226 (OMIM: 601575) PREDICTED: fos-related ( 287) 1875 249.8 5.2e-66 XP_006712040 (OMIM: 601575) PREDICTED: fos-related ( 304) 1107 152.3 1.2e-36 XP_006712039 (OMIM: 601575) PREDICTED: fos-related ( 343) 1107 152.3 1.4e-36 XP_005264288 (OMIM: 601575) PREDICTED: fos-related ( 205) 1046 144.4 2e-34 NP_005243 (OMIM: 164810) proto-oncogene c-Fos [Hom ( 380) 630 91.8 2.5e-18 NP_005429 (OMIM: 136515) fos-related antigen 1 iso ( 271) 487 73.5 5.7e-13 NP_006723 (OMIM: 164772) protein fosB isoform 1 [H ( 338) 487 73.6 6.8e-13 XP_005258748 (OMIM: 164772) PREDICTED: protein fos ( 237) 458 69.8 6.6e-12 NP_001287785 (OMIM: 136515) fos-related antigen 1 ( 205) 399 62.2 1.1e-09 NP_001193417 (OMIM: 603148) cyclic AMP-dependent t ( 124) 278 46.7 3.1e-05 NP_001193413 (OMIM: 603148) cyclic AMP-dependent t ( 124) 278 46.7 3.1e-05 NP_001025458 (OMIM: 603148) cyclic AMP-dependent t ( 181) 278 46.8 4.1e-05 XP_005273203 (OMIM: 603148) PREDICTED: cyclic AMP- ( 181) 278 46.8 4.1e-05 NP_001665 (OMIM: 603148) cyclic AMP-dependent tran ( 181) 278 46.8 4.1e-05 XP_011507881 (OMIM: 603148) PREDICTED: cyclic AMP- ( 181) 278 46.8 4.1e-05 XP_016876463 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 261 44.6 0.00017 NP_001128519 (OMIM: 608657) jun dimerization prote ( 163) 261 44.6 0.00017 XP_005267389 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 261 44.6 0.00017 XP_016876462 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 261 44.6 0.00017 XP_016876464 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 261 44.6 0.00017 NP_001128520 (OMIM: 608657) jun dimerization prote ( 163) 261 44.6 0.00017 NP_569736 (OMIM: 608657) jun dimerization protein ( 163) 261 44.6 0.00017 NP_001128521 (OMIM: 608657) jun dimerization prote ( 174) 261 44.6 0.00018 XP_016876461 (OMIM: 608657) PREDICTED: jun dimeriz ( 174) 261 44.6 0.00018 NP_001107643 (OMIM: 164772) protein fosB isoform 2 ( 302) 265 45.3 0.00019 XP_016876460 (OMIM: 608657) PREDICTED: jun dimeriz ( 206) 261 44.7 0.0002 >>NP_005244 (OMIM: 601575) fos-related antigen 2 [Homo s (326 aa) initn: 2146 init1: 2146 opt: 2146 Z-score: 1491.3 bits: 284.2 E(85289): 2.5e-76 Smith-Waterman score: 2146; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326) 10 20 30 40 50 60 pF1KB7 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 EFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 AQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESC 250 260 270 280 290 300 310 320 pF1KB7 SKAHRRSSSSGDQSSDSLNSPTLLAL :::::::::::::::::::::::::: NP_005 SKAHRRSSSSGDQSSDSLNSPTLLAL 310 320 >>XP_016859226 (OMIM: 601575) PREDICTED: fos-related ant (287 aa) initn: 1875 init1: 1875 opt: 1875 Z-score: 1306.1 bits: 249.8 E(85289): 5.2e-66 Smith-Waterman score: 1875; 100.0% identity (100.0% similar) in 287 aa overlap (40-326:1-287) 10 20 30 40 50 60 pF1KB7 DTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVI :::::::::::::::::::::::::::::: XP_016 MPGSGSAFIPTINAITTSQDLQWMVQPTVI 10 20 30 70 80 90 100 110 120 pF1KB7 TSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRI 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 RRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 VCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPI 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 SIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSS 220 230 240 250 260 270 310 320 pF1KB7 SGDQSSDSLNSPTLLAL ::::::::::::::::: XP_016 SGDQSSDSLNSPTLLAL 280 >>XP_006712040 (OMIM: 601575) PREDICTED: fos-related ant (304 aa) initn: 1861 init1: 1107 opt: 1107 Z-score: 778.6 bits: 152.3 E(85289): 1.2e-36 Smith-Waterman score: 1831; 94.4% identity (94.4% similar) in 304 aa overlap (40-326:1-304) 10 20 30 40 50 60 pF1KB7 DTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVI :::::::::::::::::::::::::::::: XP_006 MPGSGSAFIPTINAITTSQDLQWMVQPTVI 10 20 30 70 80 90 100 110 120 pF1KB7 TSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRI 40 50 60 70 80 90 130 140 150 160 170 pF1KB7 RRERNKLAAAKCRNRRRELTEKLQA-----------------ETEELEEEKSGLQKEIAE ::::::::::::::::::::::::: :::::::::::::::::: XP_006 RRERNKLAAAKCRNRRRELTEKLQAIGPWQVAVPHIPLFPWQETEELEEEKSGLQKEIAE 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 LQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPS 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB7 SSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQES 220 230 240 250 260 270 300 310 320 pF1KB7 PASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL :::::::::::::::::::::::::::::::::: XP_006 PASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL 280 290 300 >>XP_006712039 (OMIM: 601575) PREDICTED: fos-related ant (343 aa) initn: 2132 init1: 1107 opt: 1107 Z-score: 777.9 bits: 152.3 E(85289): 1.4e-36 Smith-Waterman score: 2102; 95.0% identity (95.0% similar) in 343 aa overlap (1-326:1-343) 10 20 30 40 50 60 pF1KB7 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS 70 80 90 100 110 120 130 140 150 160 pF1KB7 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQA-----------------ETEELEEEK :::::::::::::::::::::::::::::::::: ::::::::: XP_006 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAIGPWQVAVPHIPLFPWQETEELEEEK 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 SGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQ 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 EPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFT 250 260 270 280 290 300 290 300 310 320 pF1KB7 YPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL ::::::::::::::::::::::::::::::::::::::::::: XP_006 YPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL 310 320 330 340 >>XP_005264288 (OMIM: 601575) PREDICTED: fos-related ant (205 aa) initn: 1084 init1: 1046 opt: 1046 Z-score: 739.1 bits: 144.4 E(85289): 2e-34 Smith-Waterman score: 1046; 98.1% identity (99.4% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB7 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL :::::::::::::::::::::::::::::::::::. . XP_005 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAEASQKLMTFVRPLRQTETVFHSGICC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 EFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDK XP_005 PLLNEALARDRGAGGGEVRPAEGDC 190 200 >>NP_005243 (OMIM: 164810) proto-oncogene c-Fos [Homo sa (380 aa) initn: 703 init1: 560 opt: 630 Z-score: 450.0 bits: 91.8 E(85289): 2.5e-18 Smith-Waterman score: 771; 42.4% identity (64.6% similar) in 387 aa overlap (1-317:2-371) 10 20 30 40 pF1KB7 MYQDYPGNFD-TSSRGSSGSPA-------H--AESYSSGGG--GQQKFRVDMPGSGSAF :.. . .... .::: ::.::: : :.:.:: :. . : : .:. :.. : NP_005 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 IPTINAITTSQDLQWMVQPTVITSMSNPYPRS-HPYSPLPGLASVPGHMALPRPGVIKTI :::..::.:: ::::.:::....:.. :. ::.. .:. :. : : ::.::. NP_005 IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFG-VPA----PSAGAYSRAGVVKTM 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 ----GTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEE . ..::: . :::::::::::::::::::.:::::::::::::. :::::..::.: NP_005 TGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDE 120 130 140 150 160 170 170 180 190 200 pF1KB7 KSGLQKEIAELQKEKEKLEFMLVAHGPVCKIS-----PEERR--------------SP-- ::.:: :::.: ::::::::.:.:: :.::: ::: .: NP_005 KSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPES 180 190 200 210 220 230 210 220 230 240 pF1KB7 -------------PAPGLQPMRSGGGSVGAVVVKQEPLEE-DSPSSSSAGLDKAQRSVIK : :...:..: .... .: ::... :.:: . ... ::: NP_005 EEAFTLPLLNDPEPKPSVEPVKS----ISSMELKTEPFDDFLFPASSRPSGSETARSV-P 240 250 260 270 280 290 250 260 270 280 pF1KB7 PISIAGGFYGE--EPLHT------PI----------VVTSTPAVTPGTSNLVFTYPSVLE ....:.::. ::::. :. ::: ::. : ::..::::: NP_005 DMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYP---- 300 310 320 330 340 290 300 310 320 pF1KB7 QESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL :. . :: :. :::..:::.. :::: NP_005 -EADSFPS--CAAAHRKGSSSNEPSSDSLSSPTLLAL 350 360 370 380 >>NP_005429 (OMIM: 136515) fos-related antigen 1 isoform (271 aa) initn: 546 init1: 413 opt: 487 Z-score: 353.8 bits: 73.5 E(85289): 5.7e-13 Smith-Waterman score: 766; 46.7% identity (65.7% similar) in 332 aa overlap (1-326:1-271) 10 20 30 40 50 pF1KB7 MYQDY--PGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQ :..:. :: .... :. :.::. . ... .::::.. .:.::... :: NP_005 MFRDFGEPGP-SSGNGGGYGGPAQPPAAAQA--AQQKFHL---------VPSINTMSGSQ 10 20 30 40 60 70 80 90 100 110 pF1KB7 DLQWMVQPTVITSMSNPYPRSHP-YSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRD- .::::::: . : : : ..: ::: : ::::::...: : ::: NP_005 ELQWMVQPHFLGPSSYPRPLTYPQYSP-------P----QPRPGVIRALGPPPGVRRRPC 50 60 70 80 90 120 130 140 150 160 170 pF1KB7 EQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKE ::.::::::.::.::::::::::::::::.:::. :::::..::.::::::.:: ::::. NP_005 EQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQ 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 KEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSA ::.::..: :: :.::: :: :.. : :. :.:.. NP_005 KERLELVLEAHRPICKI-PE----------------GAKEG-----------DTGSTSGT 160 170 180 240 250 260 270 280 290 pF1KB7 GLDKAQRSVIKPISIAGGFYGE-EPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPAS . : . ::.. : : : :::: ..: ::..:: : .::::::: . NP_005 SSPPAPCRPVPCISLSPGPVLEPEALHTPTLMT-TPSLTPFTPSLVFTYPS--------T 190 200 210 220 230 240 300 310 320 pF1KB7 PSESCSKAHRRSSSS-GDQSSDSLNSPTLLAL : : :..:::.:::: :: ::: :.::::::: NP_005 P-EPCASAHRKSSSSSGDPSSDPLGSPTLLAL 250 260 270 >>NP_006723 (OMIM: 164772) protein fosB isoform 1 [Homo (338 aa) initn: 638 init1: 433 opt: 487 Z-score: 352.5 bits: 73.6 E(85289): 6.8e-13 Smith-Waterman score: 722; 44.0% identity (63.4% similar) in 366 aa overlap (1-326:1-338) 10 20 30 40 50 pF1KB7 MYQDYPGNFDTSSRGSSGSPAHAESYSS---------GGGGQQKFRV-DMPGSGSAFIPT :.: .::..:..:: ::. :... :: ....:. . .:::: :.:: NP_006 MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGS---FVPT 10 20 30 40 50 60 70 80 90 100 pF1KB7 INAITTSQDLQWMVQPTVITSM---------SNPYPRSHPYSPLPGLA-SVPGHMALPRP ..::::::::::.::::.:.:: :.: : ::. .:: . :.:: . NP_006 VTAITTSQDLQWLVQPTLISSMAQSQGQPLASQP-PVVDPYD-MPGTSYSTPGMSGYSSG 60 70 80 90 100 110 110 120 130 140 pF1KB7 GVI-----KTIGTTVG-----------RRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNR :. .: ::: : :: :.: :.::::::::.::::::::::::::: NP_006 GASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNR 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB7 RRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAP :::::..:::::..:::::. :..::::::::::.:::.:::: : ::: :: :.: NP_006 RRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEE---GPGP 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 G-LQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHT : : .:. ::. : :.. . : : : : : ....... :. NP_006 GPLAEVRDLPGSAPA---KEDGFSWLLPPPPPPPLP-FQTSQDAPPNLTASLF----THS 240 250 260 270 280 270 280 290 300 310 320 pF1KB7 PIVVTSTP--AVTPG-TSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNS . : . : .:.:. ::..:.: : : . . :.: :.: :: :: ::: NP_006 EVQVLGDPFPVVNPSYTSSFVLTCPEV----------SAFAGAQRTSGS--DQPSDPLNS 290 300 310 320 330 pF1KB7 PTLLAL :.:::: NP_006 PSLLAL >>XP_005258748 (OMIM: 164772) PREDICTED: protein fosB is (237 aa) initn: 641 init1: 433 opt: 458 Z-score: 334.7 bits: 69.8 E(85289): 6.6e-12 Smith-Waterman score: 642; 51.0% identity (69.3% similar) in 241 aa overlap (1-205:1-233) 10 20 30 40 50 pF1KB7 MYQDYPGNFDTSSRGSSGSPAHAESYSS---------GGGGQQKFRV-DMPGSGSAFIPT :.: .::..:..:: ::. :... :: ....:. . .:::: :.:: XP_005 MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGS---FVPT 10 20 30 40 50 60 70 80 90 100 pF1KB7 INAITTSQDLQWMVQPTVITSM---------SNPYPRSHPYSPLPGLA-SVPGHMALPRP ..::::::::::.::::.:.:: :.: : ::. .:: . :.:: . XP_005 VTAITTSQDLQWLVQPTLISSMAQSQGQPLASQP-PVVDPYD-MPGTSYSTPGMSGYSSG 60 70 80 90 100 110 110 120 130 140 pF1KB7 GVI-----KTIGTTVG-----------RRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNR :. .: ::: : :: :.: :.::::::::.::::::::::::::: XP_005 GASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNR 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB7 RRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAP :::::..:::::..:::::. :..::::::::::.:::.:::: : ::: :: :.: XP_005 RRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEE---GPGP 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 GLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTP : XP_005 GPLAE >>NP_001287785 (OMIM: 136515) fos-related antigen 1 isof (205 aa) initn: 548 init1: 395 opt: 399 Z-score: 295.1 bits: 62.2 E(85289): 1.1e-09 Smith-Waterman score: 563; 52.4% identity (68.9% similar) in 212 aa overlap (117-326:32-205) 90 100 110 120 130 140 pF1KB7 GLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRR .:.::::::.::.::::::::::::::::. NP_001 FRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQISPEEEERRRVRRERNKLAAAKCRNRRK 10 20 30 40 50 60 150 160 170 180 190 200 pF1KB7 ELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGL :::. :::::..::.::::::.:: ::::.::.::..: :: :.::: :: NP_001 ELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKI-PE---------- 70 80 90 100 110 210 220 230 240 250 260 pF1KB7 QPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGE-EPLHTPI :.. : :. :.:... : . ::.. : : : :::: NP_001 ------GAKEG-----------DTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPT 120 130 140 150 270 280 290 300 310 320 pF1KB7 VVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSS-GDQSSDSLNSPTLL ..: ::..:: : .::::::: .: : :..:::.:::: :: ::: :.::::: NP_001 LMT-TPSLTPFTPSLVFTYPS--------TP-EPCASAHRKSSSSSGDPSSDPLGSPTLL 160 170 180 190 200 pF1KB7 AL :: NP_001 AL 326 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:23:01 2016 done: Sat Nov 5 10:23:02 2016 Total Scan time: 8.050 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]