FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8006, 773 aa 1>>>pF1KB8006 773 - 773 aa - 773 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1852+/-0.000749; mu= 12.8074+/- 0.046 mean_var=118.8898+/-23.848, 0's: 0 Z-trim(112.7): 23 B-trim: 0 in 0/51 Lambda= 0.117626 statistics sampled from 13379 (13400) to 13379 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.412), width: 16 Scan time: 3.200 The best scores are: opt bits E(32554) CCDS13773.1 DGCR8 gene_id:54487|Hs108|chr22 ( 773) 5195 892.6 0 CCDS54501.1 DGCR8 gene_id:54487|Hs108|chr22 ( 740) 3640 628.7 1e-179 >>CCDS13773.1 DGCR8 gene_id:54487|Hs108|chr22 (773 aa) initn: 5195 init1: 5195 opt: 5195 Z-score: 4765.8 bits: 892.6 E(32554): 0 Smith-Waterman score: 5195; 100.0% identity (100.0% similar) in 773 aa overlap (1-773:1-773) 10 20 30 40 50 60 pF1KB8 METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 EPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGAL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESER 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 PILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 PFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 ISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQ 670 680 690 700 710 720 730 740 750 760 770 pF1KB8 YAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV 730 740 750 760 770 >>CCDS54501.1 DGCR8 gene_id:54487|Hs108|chr22 (740 aa) initn: 4975 init1: 3640 opt: 3640 Z-score: 3340.0 bits: 628.7 E(32554): 1e-179 Smith-Waterman score: 4913; 95.7% identity (95.7% similar) in 773 aa overlap (1-773:1-740) 10 20 30 40 50 60 pF1KB8 METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGAL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESER 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 PILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFEC----- 490 500 510 520 530 550 560 570 580 590 600 pF1KB8 PFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNH :::::::::::::::::::::::::::::::: CCDS54 ----------------------------ARATLEILIPDFVKQTSEEKPKDSEELEYFNH 540 550 560 610 620 630 640 650 660 pF1KB8 ISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKH 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB8 TVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQ 630 640 650 660 670 680 730 740 750 760 770 pF1KB8 YAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 YAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV 690 700 710 720 730 740 773 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:14:08 2016 done: Wed Nov 2 23:14:09 2016 Total Scan time: 3.200 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]