FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8104, 461 aa 1>>>pF1KB8104 461 - 461 aa - 461 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1832+/-0.000789; mu= 6.8213+/- 0.048 mean_var=190.4206+/-38.172, 0's: 0 Z-trim(115.0): 4 B-trim: 101 in 1/52 Lambda= 0.092943 statistics sampled from 15602 (15605) to 15602 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.479), width: 16 Scan time: 2.180 The best scores are: opt bits E(32554) CCDS10076.1 ITPKA gene_id:3706|Hs108|chr15 ( 461) 3126 431.1 1.2e-120 CCDS1555.1 ITPKB gene_id:3707|Hs108|chr1 ( 946) 1448 206.4 1.1e-52 CCDS12563.1 ITPKC gene_id:80271|Hs108|chr19 ( 683) 1291 185.2 1.8e-46 >>CCDS10076.1 ITPKA gene_id:3706|Hs108|chr15 (461 aa) initn: 3126 init1: 3126 opt: 3126 Z-score: 2279.8 bits: 431.1 E(32554): 1.2e-120 Smith-Waterman score: 3126; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461) 10 20 30 40 50 60 pF1KB8 MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 STSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 STSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVER 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 DGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 TEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 TEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKT 370 380 390 400 410 420 430 440 450 460 pF1KB8 TPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER ::::::::::::::::::::::::::::::::::::::::: CCDS10 TPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER 430 440 450 460 >>CCDS1555.1 ITPKB gene_id:3707|Hs108|chr1 (946 aa) initn: 1400 init1: 1189 opt: 1448 Z-score: 1059.5 bits: 206.4 E(32554): 1.1e-52 Smith-Waterman score: 1448; 57.2% identity (76.5% similar) in 400 aa overlap (67-460:545-941) 40 50 60 70 80 90 pF1KB8 LFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSP :. ::. : : . . .. : : :. CCDS15 KAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDM 520 530 540 550 560 570 100 110 120 130 140 150 pF1KB8 GPPERERDCLPAAGSSHLQQP-RRLSTSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQL : : . . :: . . : :.::.::.:::: :: ::::.:. :: : : . CCDS15 GTQE-DGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAF 580 590 600 610 620 630 160 170 180 190 200 210 pF1KB8 EAGEDVGQK----NHWQKIRTMVNL-PVISPFKKRYAWVQLAGHTGSFKAAGTSGLILKR : :: . :.::..::. : . :::.: :.:::::.::::::. .: :::. CCDS15 LHTLD-QQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAA-NGRILKK 640 650 660 670 680 690 220 230 240 250 260 270 pF1KB8 CSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTY : :. :: :::.:.:: :::.:: : .::: : :..::: ::.:::.:::::.::: CCDS15 HCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTY 700 710 720 730 740 750 280 290 300 310 320 330 pF1KB8 LEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGF :::::::::..:.::::::.::. ::::::::::.::::::::::::::: :::..:::: CCDS15 LEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGF 760 770 780 790 800 810 340 350 360 370 380 390 pF1KB8 RIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFF ::::::: ::. . ::: :..:::: ..:.::..:....: : .::. :: ::::: :: CCDS15 RIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFF 820 830 840 850 860 870 400 410 420 430 440 450 pF1KB8 RRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDN . ::::::::::.::. ..: ::.::::::::::.:: :.: ::.::::::::: ::.: CCDS15 KCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNN 880 890 900 910 920 930 460 pF1KB8 LIGILASLAER :. ::. ... CCDS15 LVDILTEMSQDAPLA 940 >>CCDS12563.1 ITPKC gene_id:80271|Hs108|chr19 (683 aa) initn: 1253 init1: 1145 opt: 1291 Z-score: 947.6 bits: 185.2 E(32554): 1.8e-46 Smith-Waterman score: 1311; 53.1% identity (75.4% similar) in 390 aa overlap (73-460:322-682) 50 60 70 80 90 100 pF1KB8 AAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSP-GPPER .: :: :.: .: : :. : ..: ::: : CCDS12 DCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPV-PRLIITPETPE-PEAQPVGPPSR 300 310 320 330 340 110 120 130 140 150 160 pF1KB8 ERDCLPAAGSSHLQQPRRLSTSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDV . .::. . ::.:: ...::::... . . : :: CCDS12 VE-----GGSGGF--------SSASS------FDESEDDVVAGGGGASD-------PEDR 350 360 370 380 170 180 190 200 210 220 pF1KB8 GQKNHWQKIRTMVNL-PVISPFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLA . .. :.:..:... : . :.:.: ::::.::.:.:.: : .: :::: . :. : CCDS12 SGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGNFQA-GEDGRILKRFCQCEQRSLE 390 400 410 420 430 440 230 240 250 260 270 280 pF1KB8 RLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARE .:: : :: :::..:.: .::... :..::: :.:: ..::::: ::::::::.:::: CCDS12 QLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARE 450 460 470 480 490 500 290 300 310 320 330 340 pF1KB8 RPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADG ::. :::::.::.:::: ::: ::::: :::::::::::: .::..:::::::::::::: CCDS12 RPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADG 510 520 530 540 550 560 350 360 370 380 390 400 pF1KB8 SCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSL .:.:.:: :.. ::: .:.:.::.::. .:..:. :...:..::.: ::. :::.:::: CCDS12 TCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSL 570 580 590 600 610 620 410 420 430 440 450 460 pF1KB8 LFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAE :::::: : ::.::::::. ::: : :.:: :: ::::::::: ::::.: .: .::. CCDS12 LFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLAQ 630 640 650 660 670 680 pF1KB8 R CCDS12 S 461 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:30:08 2016 done: Fri Nov 4 09:30:09 2016 Total Scan time: 2.180 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]