FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8107, 222 aa 1>>>pF1KB8107 222 - 222 aa - 222 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8042+/-0.000727; mu= 8.7929+/- 0.044 mean_var=110.5962+/-21.965, 0's: 0 Z-trim(112.4): 13 B-trim: 0 in 0/52 Lambda= 0.121956 statistics sampled from 13149 (13162) to 13149 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.404), width: 16 Scan time: 1.980 The best scores are: opt bits E(32554) CCDS33236.1 CHMP3 gene_id:51652|Hs108|chr2 ( 222) 1385 253.4 8.4e-68 CCDS56128.1 CHMP3 gene_id:100526767|Hs108|chr2 ( 251) 1282 235.3 2.7e-62 CCDS42707.1 CHMP3 gene_id:51652|Hs108|chr2 ( 156) 957 178.0 2.9e-45 CCDS54375.1 CHMP3 gene_id:51652|Hs108|chr2 ( 182) 688 130.7 5.9e-31 CCDS2918.1 CHMP2B gene_id:25978|Hs108|chr3 ( 213) 311 64.4 6.2e-11 CCDS12986.1 CHMP2A gene_id:27243|Hs108|chr19 ( 222) 308 63.9 9.3e-11 >>CCDS33236.1 CHMP3 gene_id:51652|Hs108|chr2 (222 aa) initn: 1385 init1: 1385 opt: 1385 Z-score: 1330.7 bits: 253.4 E(32554): 8.4e-68 Smith-Waterman score: 1385; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222) 10 20 30 40 50 60 pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA 130 140 150 160 170 180 190 200 210 220 pF1KB8 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS :::::::::::::::::::::::::::::::::::::::::: CCDS33 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS 190 200 210 220 >>CCDS56128.1 CHMP3 gene_id:100526767|Hs108|chr2 (251 aa) initn: 1282 init1: 1282 opt: 1282 Z-score: 1232.0 bits: 235.3 E(32554): 2.7e-62 Smith-Waterman score: 1282; 100.0% identity (100.0% similar) in 207 aa overlap (16-222:45-251) 10 20 30 40 pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVK :::::::::::::::::::::::::::::: CCDS56 SESVSSTNFSGEMHFYELVEDTKDGIWLVQVNEWSLKIRKEMRVVDRQIRDIQREEEKVK 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB8 RSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 RSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQ 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB8 KSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEI 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB8 DRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 DRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS 200 210 220 230 240 250 >>CCDS42707.1 CHMP3 gene_id:51652|Hs108|chr2 (156 aa) initn: 957 init1: 957 opt: 957 Z-score: 926.0 bits: 178.0 E(32554): 2.9e-45 Smith-Waterman score: 957; 100.0% identity (100.0% similar) in 156 aa overlap (67-222:1-156) 40 50 60 70 80 90 pF1KB8 IQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLA :::::::::::::::::::::::::::::: CCDS42 MIRSRKAVSKLYASKAHMNSVLMGMKNQLA 10 20 30 100 110 120 130 140 150 pF1KB8 VLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEE 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 MEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSR 100 110 120 130 140 150 220 pF1KB8 LATLRS :::::: CCDS42 LATLRS >>CCDS54375.1 CHMP3 gene_id:51652|Hs108|chr2 (182 aa) initn: 688 init1: 688 opt: 688 Z-score: 669.2 bits: 130.7 E(32554): 5.9e-31 Smith-Waterman score: 1057; 82.0% identity (82.0% similar) in 222 aa overlap (1-222:1-182) 10 20 30 40 50 60 pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI ::::::::::: ::::::::: CCDS54 IVLAKEMIRSR----------------------------------------KAMQSLVKI 70 80 130 140 150 160 170 180 pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA 90 100 110 120 130 140 190 200 210 220 pF1KB8 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS :::::::::::::::::::::::::::::::::::::::::: CCDS54 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS 150 160 170 180 >>CCDS2918.1 CHMP2B gene_id:25978|Hs108|chr3 (213 aa) initn: 315 init1: 241 opt: 311 Z-score: 309.7 bits: 64.4 E(32554): 6.2e-11 Smith-Waterman score: 311; 27.5% identity (69.1% similar) in 207 aa overlap (8-210:6-210) 10 20 30 40 50 60 pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC ..: ....: . ..: .:.. :. ....:.... .: :: :.:..: CCDS29 MASLFKKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEAC 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI ::::.... :: .. .: .....:. : . . ...::... ....:.:... . CCDS29 KVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDP 60 70 80 90 100 110 130 140 150 160 170 pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDT----FESMDDQEEMEEEAEMEIDRILFEITAGA . ::....:: :: . :::..:: :.. ::.:: .. ... .:.: .::. : CCDS29 QKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEIS-GK 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 LGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS ..:::: .. .:: : ..:. :.. .:: CCDS29 MAKAPS-AARSLPSASTSKATISDEEIERQLKALGVD 180 190 200 210 >>CCDS12986.1 CHMP2A gene_id:27243|Hs108|chr19 (222 aa) initn: 288 init1: 288 opt: 308 Z-score: 306.6 bits: 63.9 E(32554): 9.3e-11 Smith-Waterman score: 308; 27.4% identity (63.0% similar) in 219 aa overlap (3-220:4-212) 10 20 30 40 50 pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV :::. .: :.::. . . . . :: .::. . .. .:.:. ..: ::.:: :. CCDS12 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK ..::...:.:. : :. .:....: . ... . .: ... :..: .:. .: CCDS12 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK .:.:: : :. .. . :::..:.... .:: :::.. ....: : :: CCDS12 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDE-----LGL 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 APSKVTDALPE-PEPPGAMAASEDEEEEEEALEAMQSRLATLRS . .:: : . : :..... .. : : :. . : : CCDS12 S---LTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD 180 190 200 210 220 222 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:33:09 2016 done: Fri Nov 4 09:33:09 2016 Total Scan time: 1.980 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]