Result of FASTA (omim) for
pF1KB8108
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8108, 478 aa
1>>>pF1KB8108 478 - 478 aa - 478 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8152+/-0.000399; mu= 7.1765+/- 0.025
mean_var=170.0228+/-33.944, 0's: 0 Z-trim(117.7): 9 B-trim: 0 in 0/55
Lambda= 0.098360
statistics sampled from 29856 (29861) to 29856 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.35), width: 16
Scan time: 8.210
The best scores are: opt bits E(85289)
NP_006829 (OMIM: 601870) methionine aminopeptidase ( 478) 3253 473.9 4.3e-133
NP_001317175 (OMIM: 601870) methionine aminopeptid ( 477) 3236 471.5 2.3e-132
NP_001304112 (OMIM: 601870) methionine aminopeptid ( 455) 2553 374.6 3.3e-103
NP_001304111 (OMIM: 601870) methionine aminopeptid ( 455) 2374 349.2 1.5e-95
NP_006182 (OMIM: 602145) proliferation-associated ( 394) 385 66.9 1.2e-10
>>NP_006829 (OMIM: 601870) methionine aminopeptidase 2 i (478 aa)
initn: 3253 init1: 3253 opt: 3253 Z-score: 2510.5 bits: 473.9 E(85289): 4.3e-133
Smith-Waterman score: 3253; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478)
10 20 30 40 50 60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
370 380 390 400 410 420
430 440 450 460 470
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
430 440 450 460 470
>>NP_001317175 (OMIM: 601870) methionine aminopeptidase (477 aa)
initn: 3001 init1: 3001 opt: 3236 Z-score: 2497.4 bits: 471.5 E(85289): 2.3e-132
Smith-Waterman score: 3236; 99.8% identity (99.8% similar) in 478 aa overlap (1-478:1-477)
10 20 30 40 50 60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_001 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA-GEQEPDKES
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
360 370 380 390 400 410
430 440 450 460 470
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
420 430 440 450 460 470
>>NP_001304112 (OMIM: 601870) methionine aminopeptidase (455 aa)
initn: 2904 init1: 2546 opt: 2553 Z-score: 1973.9 bits: 374.6 E(85289): 3.3e-103
Smith-Waterman score: 3020; 95.0% identity (95.0% similar) in 478 aa overlap (1-478:1-455)
10 20 30 40 50 60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_001 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA-GEQEPDKES
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
:::::::::::::::::::::::::: :::::::::::
NP_001 GASVDEVARQLERSALEDKERDEDDE----------------------AKVQTDPPSVPI
60 70 80 90
130 140 150 160 170 180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
340 350 360 370 380 390
430 440 450 460 470
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
400 410 420 430 440 450
>>NP_001304111 (OMIM: 601870) methionine aminopeptidase (455 aa)
initn: 2374 init1: 2374 opt: 2374 Z-score: 1836.6 bits: 349.2 E(85289): 1.5e-95
Smith-Waterman score: 3012; 95.0% identity (95.0% similar) in 478 aa overlap (1-478:1-455)
10 20 30 40 50 60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGR-----------
70 80 90 100
130 140 150 160 170 180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------QECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
110 120 130 140 150
190 200 210 220 230 240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
340 350 360 370 380 390
430 440 450 460 470
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
400 410 420 430 440 450
>>NP_006182 (OMIM: 602145) proliferation-associated prot (394 aa)
initn: 141 init1: 108 opt: 385 Z-score: 312.1 bits: 66.9 E(85289): 1.2e-10
Smith-Waterman score: 385; 23.8% identity (59.8% similar) in 336 aa overlap (153-475:5-336)
130 140 150 160 170 180
pF1KB8 LYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKY
.:.. : . . . .. ... .: .
NP_006 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRS
10 20 30
190 200 210 220 230
pF1KB8 VMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAG
.. . :.... .::: .:. .. . ::. .. :.::::. :.:::. :..: .
NP_006 LVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKS
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB8 DTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTGIKCAGIDV
: .:. :. :::.:.:..: : . : : . . : . . : :. ... :: .
NP_006 DQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAAL
100 110 120 130 140 150
300 310 320 330 340
pF1KB8 RLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV---PI---VKG
:: :. .: :... .. ..... ::... .:.. :. : . ::. : :
NP_006 RLVKPGNQNTQVTEAWN-KV-AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKD
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN
: ...: ::::.... :.:.: ..: . . .: . ... .. ... ...
NP_006 HEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERR
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB8 FGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCK
: .. : : .. :.: :.. . ...:. : . .: ..:::. :.:: :.
NP_006 FDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGP
280 290 300 310 320 330
470
pF1KB8 EVVSRGDDY
.. :
NP_006 MRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEEN
340 350 360 370 380 390
478 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:33:55 2016 done: Fri Nov 4 09:33:56 2016
Total Scan time: 8.210 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]