Result of FASTA (omim) for
pF1KB8111
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8111, 556 aa
1>>>pF1KB8111 556 - 556 aa - 556 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4591+/-0.000477; mu= -4.3016+/- 0.029
mean_var=552.5393+/-122.750, 0's: 0 Z-trim(120.4): 1765 B-trim: 0 in 0/57
Lambda= 0.054562
statistics sampled from 33077 (35654) to 33077 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.418), width: 16
Scan time: 9.830
The best scores are: opt bits E(85289)
NP_002604 (OMIM: 605213) 3-phosphoinositide-depend ( 556) 3764 311.8 3.7e-84
XP_011520823 (OMIM: 605213) PREDICTED: 3-phosphoin ( 590) 3718 308.2 4.8e-83
XP_016878762 (OMIM: 605213) PREDICTED: 3-phosphoin ( 566) 3478 289.3 2.3e-77
XP_016878761 (OMIM: 605213) PREDICTED: 3-phosphoin ( 568) 3432 285.6 2.8e-76
XP_016878760 (OMIM: 605213) PREDICTED: 3-phosphoin ( 600) 3432 285.7 2.9e-76
XP_016878763 (OMIM: 605213) PREDICTED: 3-phosphoin ( 539) 3298 275.1 4.1e-73
NP_001248745 (OMIM: 605213) 3-phosphoinositide-dep ( 454) 2986 250.4 9.1e-66
NP_112558 (OMIM: 605213) 3-phosphoinositide-depend ( 429) 2194 188.0 5.2e-47
XP_011520825 (OMIM: 605213) PREDICTED: 3-phosphoin ( 463) 2194 188.1 5.4e-47
XP_016878766 (OMIM: 605213) PREDICTED: 3-phosphoin ( 350) 2039 175.7 2.2e-43
XP_016878765 (OMIM: 605213) PREDICTED: 3-phosphoin ( 439) 1908 165.5 3.1e-40
XP_016878764 (OMIM: 605213) PREDICTED: 3-phosphoin ( 473) 1908 165.6 3.3e-40
NP_005035 (OMIM: 300083) cAMP-dependent protein ki ( 358) 734 73.0 1.8e-12
NP_005618 (OMIM: 602958) serine/threonine-protein ( 431) 732 72.9 2.3e-12
NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 732 72.9 2.3e-12
NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 732 73.0 2.4e-12
NP_001137148 (OMIM: 602958) serine/threonine-prote ( 526) 732 73.0 2.6e-12
XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 732 73.0 2.6e-12
NP_001229791 (OMIM: 176892) cAMP-dependent protein ( 338) 719 71.8 4e-12
XP_005271076 (OMIM: 176892) PREDICTED: cAMP-depend ( 338) 719 71.8 4e-12
NP_001229787 (OMIM: 176892) cAMP-dependent protein ( 339) 719 71.8 4e-12
XP_005271075 (OMIM: 176892) PREDICTED: cAMP-depend ( 346) 719 71.8 4.1e-12
XP_005271074 (OMIM: 176892) PREDICTED: cAMP-depend ( 347) 719 71.8 4.1e-12
XP_005271073 (OMIM: 176892) PREDICTED: cAMP-depend ( 349) 719 71.8 4.1e-12
XP_005271072 (OMIM: 176892) PREDICTED: cAMP-depend ( 350) 719 71.8 4.1e-12
NP_002722 (OMIM: 176892) cAMP-dependent protein ki ( 351) 719 71.8 4.1e-12
XP_006710821 (OMIM: 176892) PREDICTED: cAMP-depend ( 354) 719 71.8 4.1e-12
NP_001229788 (OMIM: 176892) cAMP-dependent protein ( 355) 719 71.8 4.1e-12
NP_001229789 (OMIM: 176892) cAMP-dependent protein ( 357) 719 71.8 4.2e-12
NP_001229786 (OMIM: 176892) cAMP-dependent protein ( 358) 719 71.8 4.2e-12
NP_891993 (OMIM: 176892) cAMP-dependent protein ki ( 398) 719 71.9 4.4e-12
NP_997401 (OMIM: 601639,615830) cAMP-dependent pro ( 343) 711 71.1 6.3e-12
NP_002721 (OMIM: 601639,615830) cAMP-dependent pro ( 351) 711 71.1 6.4e-12
NP_002723 (OMIM: 176893,616176) cAMP-dependent pro ( 351) 710 71.1 6.7e-12
NP_001291278 (OMIM: 601639,615830) cAMP-dependent ( 427) 711 71.3 7.1e-12
NP_057360 (OMIM: 607589) serine/threonine-protein ( 427) 708 71.0 8.4e-12
NP_001186193 (OMIM: 607589) serine/threonine-prote ( 367) 690 69.5 2.1e-11
NP_733794 (OMIM: 607589) serine/threonine-protein ( 367) 690 69.5 2.1e-11
NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 686 69.3 2.9e-11
NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 686 69.4 3e-11
XP_011523404 (OMIM: 608938) PREDICTED: ribosomal p ( 391) 684 69.1 3e-11
NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 686 69.4 3.1e-11
NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 686 69.4 3.1e-11
NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ( 419) 683 69.1 3.2e-11
NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ( 419) 683 69.1 3.2e-11
XP_016880418 (OMIM: 608938) PREDICTED: ribosomal p ( 436) 683 69.1 3.3e-11
XP_011524922 (OMIM: 125853,164731,240900) PREDICTE ( 481) 683 69.1 3.5e-11
XP_011524916 (OMIM: 125853,164731,240900) PREDICTE ( 481) 683 69.1 3.5e-11
XP_011524921 (OMIM: 125853,164731,240900) PREDICTE ( 481) 683 69.1 3.5e-11
XP_016881959 (OMIM: 125853,164731,240900) PREDICTE ( 481) 683 69.1 3.5e-11
>>NP_002604 (OMIM: 605213) 3-phosphoinositide-dependent (556 aa)
initn: 3764 init1: 3764 opt: 3764 Z-score: 1631.8 bits: 311.8 E(85289): 3.7e-84
Smith-Waterman score: 3764; 100.0% identity (100.0% similar) in 556 aa overlap (1-556:1-556)
10 20 30 40 50 60
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQ
490 500 510 520 530 540
550
pF1KB8 EVWRQRYQSHPDAAVQ
::::::::::::::::
NP_002 EVWRQRYQSHPDAAVQ
550
>>XP_011520823 (OMIM: 605213) PREDICTED: 3-phosphoinosit (590 aa)
initn: 3718 init1: 3718 opt: 3718 Z-score: 1612.0 bits: 308.2 E(85289): 4.8e-83
Smith-Waterman score: 3718; 100.0% identity (100.0% similar) in 548 aa overlap (9-556:43-590)
10 20 30
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTP
::::::::::::::::::::::::::::::
XP_011 RFLRLAARLSLRTRLEAVGSPRLVALCLPWYDAVPIQSSVVLCSCPSPSMVRTQTESSTP
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 PGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB8 ARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB8 LSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMH
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB8 IQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAG
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB8 LPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB8 HPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLS
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB8 ASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLIL
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB8 KMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHT
500 510 520 530 540 550
520 530 540 550
pF1KB8 PNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ
::::::::::::::::::::::::::::::::::::::
XP_011 PNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ
560 570 580 590
>>XP_016878762 (OMIM: 605213) PREDICTED: 3-phosphoinosit (566 aa)
initn: 3478 init1: 3478 opt: 3478 Z-score: 1510.0 bits: 289.3 E(85289): 2.3e-77
Smith-Waterman score: 3478; 100.0% identity (100.0% similar) in 518 aa overlap (1-518:1-518)
10 20 30 40 50 60
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQ
::::::::::::::::::::::::::::::::::::::
XP_016 GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTVSLFPGISVCRVMGGLCTTWEA
490 500 510 520 530 540
550
pF1KB8 EVWRQRYQSHPDAAVQ
XP_016 ATGLGQREQRGSGQLPRPFRHPRRPH
550 560
>>XP_016878761 (OMIM: 605213) PREDICTED: 3-phosphoinosit (568 aa)
initn: 3432 init1: 3432 opt: 3432 Z-score: 1490.5 bits: 285.6 E(85289): 2.8e-76
Smith-Waterman score: 3432; 100.0% identity (100.0% similar) in 510 aa overlap (9-518:11-520)
10 20 30 40 50
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGRRAVAYPQYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 RPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 IKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 ETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQAR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 YDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 TAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 LDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 TEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRK
::::::::::::::::::::::::::::::::::::::::
XP_016 TEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTVSLFPGISVCRVMGGLCTTW
490 500 510 520 530 540
540 550
pF1KB8 IQEVWRQRYQSHPDAAVQ
XP_016 EAATGLGQREQRGSGQLPRPFRHPRRPH
550 560
>>XP_016878760 (OMIM: 605213) PREDICTED: 3-phosphoinosit (600 aa)
initn: 3432 init1: 3432 opt: 3432 Z-score: 1490.2 bits: 285.7 E(85289): 2.9e-76
Smith-Waterman score: 3432; 100.0% identity (100.0% similar) in 510 aa overlap (9-518:43-552)
10 20 30
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTP
::::::::::::::::::::::::::::::
XP_016 RFLRLAARLSLRTRLEAVGSPRLVALCLPWYDAVPIQSSVVLCSCPSPSMVRTQTESSTP
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 PGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB8 ARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB8 LSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMH
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB8 IQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAG
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB8 LPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB8 HPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLS
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB8 ASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLIL
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB8 KMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHT
500 510 520 530 540 550
520 530 540 550
pF1KB8 PNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ
XP_016 VSLFPGISVCRVMGGLCTTWEAATGLGQREQRGSGQLPRPFRHPRRPH
560 570 580 590 600
>>XP_016878763 (OMIM: 605213) PREDICTED: 3-phosphoinosit (539 aa)
initn: 3298 init1: 3298 opt: 3298 Z-score: 1433.7 bits: 275.1 E(85289): 4.1e-73
Smith-Waterman score: 3298; 100.0% identity (100.0% similar) in 491 aa overlap (28-518:1-491)
10 20 30 40 50 60
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
:::::::::::::::::::::::::::::::::
XP_016 MVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
10 20 30
70 80 90 100 110 120
pF1KB8 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB8 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB8 GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQ
::::::::::::::::::::::::::::::::::::::
XP_016 GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTVSLFPGISVCRVMGGLCTTWEA
460 470 480 490 500 510
550
pF1KB8 EVWRQRYQSHPDAAVQ
XP_016 ATGLGQREQRGSGQLPRPFRHPRRPH
520 530
>>NP_001248745 (OMIM: 605213) 3-phosphoinositide-depende (454 aa)
initn: 2986 init1: 2986 opt: 2986 Z-score: 1301.7 bits: 250.4 E(85289): 9.1e-66
Smith-Waterman score: 2986; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
:::::::::::::::::::::::::::
NP_001 SNSFELDLQFSEDEKRLLLEKQAGGNPCLTGRII
430 440 450
>>NP_112558 (OMIM: 605213) 3-phosphoinositide-dependent (429 aa)
initn: 2192 init1: 2192 opt: 2194 Z-score: 965.0 bits: 188.0 E(85289): 5.2e-47
Smith-Waterman score: 2664; 77.0% identity (77.2% similar) in 556 aa overlap (1-556:1-429)
10 20 30 40 50 60
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYA-----------
70 80 90 100
130 140 150 160 170 180
pF1KB8 ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
NP_112 ------------------------------------------------------------
190 200 210 220 230 240
pF1KB8 CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
.:::
NP_112 --------------------------------------------------------TRAN
110
250 260 270 280 290 300
pF1KB8 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
120 130 140 150 160 170
310 320 330 340 350 360
pF1KB8 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
180 190 200 210 220 230
370 380 390 400 410 420
pF1KB8 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
240 250 260 270 280 290
430 440 450 460 470 480
pF1KB8 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
300 310 320 330 340 350
490 500 510 520 530 540
pF1KB8 GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQ
360 370 380 390 400 410
550
pF1KB8 EVWRQRYQSHPDAAVQ
::::::::::::::::
NP_112 EVWRQRYQSHPDAAVQ
420
>>XP_011520825 (OMIM: 605213) PREDICTED: 3-phosphoinosit (463 aa)
initn: 2192 init1: 2192 opt: 2194 Z-score: 964.7 bits: 188.1 E(85289): 5.4e-47
Smith-Waterman score: 2618; 76.6% identity (76.8% similar) in 548 aa overlap (9-556:43-463)
10 20 30
pF1KB8 MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTP
::::::::::::::::::::::::::::::
XP_011 RFLRLAARLSLRTRLEAVGSPRLVALCLPWYDAVPIQSSVVLCSCPSPSMVRTQTESSTP
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 PGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB8 ARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFG
:::::::::::
XP_011 ARELATSREYA-------------------------------------------------
140
160 170 180 190 200 210
pF1KB8 LSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMH
XP_011 ------------------------------------------------------------
220 230 240 250 260 270
pF1KB8 IQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAG
.:::::::::::::::::::::::::::::::::::::::::
XP_011 ------------------TRANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAG
150 160 170 180
280 290 300 310 320 330
pF1KB8 LPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKA
190 200 210 220 230 240
340 350 360 370 380 390
pF1KB8 HPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLS
250 260 270 280 290 300
400 410 420 430 440 450
pF1KB8 ASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLIL
310 320 330 340 350 360
460 470 480 490 500 510
pF1KB8 KMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHT
370 380 390 400 410 420
520 530 540 550
pF1KB8 PNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ
::::::::::::::::::::::::::::::::::::::
XP_011 PNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ
430 440 450 460
>>XP_016878766 (OMIM: 605213) PREDICTED: 3-phosphoinosit (350 aa)
initn: 2039 init1: 2039 opt: 2039 Z-score: 900.0 bits: 175.7 E(85289): 2.2e-43
Smith-Waterman score: 2039; 100.0% identity (100.0% similar) in 302 aa overlap (217-518:1-302)
190 200 210 220 230 240
pF1KB8 AEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTA
::::::::::::::::::::::::::::::
XP_016 MHIQITDFGTAKVLSPESKQARANSFVGTA
10 20 30
250 260 270 280 290 300
pF1KB8 QYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFF
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB8 PKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMS
100 110 120 130 140 150
370 380 390 400 410 420
pF1KB8 EDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFEL
160 170 180 190 200 210
430 440 450 460 470 480
pF1KB8 DLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYY
220 230 240 250 260 270
490 500 510 520 530 540
pF1KB8 VDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQR
::::::::::::::::::::::::::::::::
XP_016 VDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTVSLFPGISVCRVMGGLCTTWEAATGLGQ
280 290 300 310 320 330
550
pF1KB8 YQSHPDAAVQ
XP_016 REQRGSGQLPRPFRHPRRPH
340 350
556 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:37:10 2016 done: Fri Nov 4 09:37:11 2016
Total Scan time: 9.830 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]