FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8127, 451 aa 1>>>pF1KB8127 451 - 451 aa - 451 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8072+/-0.000455; mu= 14.9109+/- 0.028 mean_var=70.6040+/-13.994, 0's: 0 Z-trim(110.8): 67 B-trim: 243 in 1/49 Lambda= 0.152637 statistics sampled from 19198 (19265) to 19198 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.226), width: 16 Scan time: 5.790 The best scores are: opt bits E(85289) NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 2995 669.0 6.9e-192 NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 2941 657.1 2.6e-188 NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 2085 468.7 1.5e-131 XP_016879942 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 1904 428.7 1e-119 XP_011522916 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 1904 428.7 1e-119 XP_016879944 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 1780 401.4 1.5e-111 XP_016879945 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 1780 401.4 1.5e-111 XP_016879946 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 1780 401.4 1.5e-111 XP_016879943 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 1780 401.4 1.5e-111 NP_006079 (OMIM: 602660) tubulin beta-4B chain [Ho ( 445) 997 229.1 1.9e-59 NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 992 228.0 4.1e-59 NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 992 228.0 4.1e-59 NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 991 227.7 4.7e-59 NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 990 227.5 5.5e-59 NP_001290453 (OMIM: 615103) tubulin beta-6 chain i ( 446) 988 227.1 7.5e-59 NP_115914 (OMIM: 615103) tubulin beta-6 chain isof ( 446) 988 227.1 7.5e-59 NP_006078 (OMIM: 602662) tubulin beta-4A chain iso ( 444) 987 226.9 8.7e-59 NP_001276058 (OMIM: 602662) tubulin beta-4A chain ( 444) 987 226.9 8.7e-59 NP_001276056 (OMIM: 602662) tubulin beta-4A chain ( 489) 987 226.9 9.5e-59 NP_001276052 (OMIM: 602662) tubulin beta-4A chain ( 495) 987 226.9 9.6e-59 NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 981 225.5 2.2e-58 NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 967 222.5 1.9e-57 NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 905 208.8 2.5e-53 XP_016883574 (OMIM: 612901,613112) PREDICTED: tubu ( 429) 853 197.3 6.5e-50 NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 831 192.5 1.7e-48 NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 817 189.4 1.6e-47 NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 807 187.2 7.6e-47 NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 804 186.6 1.2e-46 NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 804 186.6 1.2e-46 NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain ( 450) 802 186.1 1.6e-46 NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 786 182.6 1.9e-45 XP_011517761 (OMIM: 616768,616780) PREDICTED: tubu ( 372) 778 180.8 5.3e-45 NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 770 179.1 2.1e-44 NP_001290456 (OMIM: 615103) tubulin beta-6 chain i ( 374) 762 177.3 6.2e-44 NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 759 176.6 9.7e-44 NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 759 176.6 9.7e-44 NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 754 175.5 2.1e-43 NP_001276059 (OMIM: 602662) tubulin beta-4A chain ( 372) 753 175.3 2.4e-43 NP_001276060 (OMIM: 602662) tubulin beta-4A chain ( 372) 753 175.3 2.4e-43 NP_001290455 (OMIM: 615103) tubulin beta-6 chain i ( 409) 733 170.9 5.6e-42 NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 725 169.1 1.7e-41 NP_001290457 (OMIM: 615103) tubulin beta-6 chain i ( 381) 725 169.1 1.8e-41 NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 698 163.2 1.2e-39 XP_016871681 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 678 158.8 2.1e-38 XP_016871682 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 678 158.8 2.1e-38 NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 632 148.7 2.6e-35 XP_016880205 (OMIM: 607344) PREDICTED: tubulin del ( 375) 553 131.3 4.4e-30 NP_001180539 (OMIM: 607344) tubulin delta chain is ( 396) 553 131.3 4.6e-30 NP_057345 (OMIM: 607344) tubulin delta chain isofo ( 453) 553 131.3 5.2e-30 XP_011523173 (OMIM: 607344) PREDICTED: tubulin del ( 406) 546 129.7 1.4e-29 >>NP_057521 (OMIM: 605785) tubulin gamma-2 chain isoform (451 aa) initn: 2995 init1: 2995 opt: 2995 Z-score: 3566.0 bits: 669.0 E(85289): 6.9e-192 Smith-Waterman score: 2995; 99.8% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB8 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDVFKDNFDE ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: NP_057 SRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDE 370 380 390 400 410 420 430 440 450 pF1KB8 MDRSREVVQELIDEYHAATQPDYISWGTQEQ ::::::::::::::::::::::::::::::: NP_057 MDRSREVVQELIDEYHAATQPDYISWGTQEQ 430 440 450 >>NP_001061 (OMIM: 191135,615412) tubulin gamma-1 chain (451 aa) initn: 2941 init1: 2941 opt: 2941 Z-score: 3501.7 bits: 657.1 E(85289): 2.6e-188 Smith-Waterman score: 2941; 97.6% identity (99.3% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB8 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSD ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_001 IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDVFKDNFDE ::::::::::::::::::::::::::::: .:.:.::::::.::::::::::.::::::: NP_001 SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE 370 380 390 400 410 420 430 440 450 pF1KB8 MDRSREVVQELIDEYHAATQPDYISWGTQEQ :: :::.::.:::::::::.::::::::::: NP_001 MDTSREIVQQLIDEYHAATRPDYISWGTQEQ 430 440 450 >>NP_001307438 (OMIM: 605785) tubulin gamma-2 chain isof (460 aa) initn: 2085 init1: 2085 opt: 2085 Z-score: 2482.9 bits: 468.7 E(85289): 1.5e-131 Smith-Waterman score: 2967; 97.8% identity (98.0% similar) in 460 aa overlap (1-451:1-460) 10 20 30 40 50 60 pF1KB8 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 IIDREADGSDSLE---------GFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSV ::::::::::::: :::::::::::::::::::::::::::::::::::::: NP_001 IIDREADGSDSLELQNSSRVIKGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 FPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 VSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 DVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPW 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 GPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKE 370 380 390 400 410 420 420 430 440 450 pF1KB8 DVFKDNFDEMDRSREVVQELIDEYHAATQPDYISWGTQEQ :.:::::::::::::::::::::::::::::::::::::: NP_001 DMFKDNFDEMDRSREVVQELIDEYHAATQPDYISWGTQEQ 430 440 450 460 >>XP_016879942 (OMIM: 605785) PREDICTED: tubulin gamma-2 (298 aa) initn: 1904 init1: 1904 opt: 1904 Z-score: 2270.4 bits: 428.7 E(85289): 1e-119 Smith-Waterman score: 1904; 99.7% identity (100.0% similar) in 292 aa overlap (160-451:7-298) 130 140 150 160 170 180 pF1KB8 DSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSL :::::::::::::::::::::::::::::: XP_016 MEVTVWRYPKKLVQTYSVFPYQDEMSDVVVQPYNSL 10 20 30 190 200 210 220 230 240 pF1KB8 LTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYM 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB8 NNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGR 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB8 DRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB8 AHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDVFKDNFDEMDRSREVVQ :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 AHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQ 220 230 240 250 260 270 430 440 450 pF1KB8 ELIDEYHAATQPDYISWGTQEQ :::::::::::::::::::::: XP_016 ELIDEYHAATQPDYISWGTQEQ 280 290 >>XP_011522916 (OMIM: 605785) PREDICTED: tubulin gamma-2 (298 aa) initn: 1904 init1: 1904 opt: 1904 Z-score: 2270.4 bits: 428.7 E(85289): 1e-119 Smith-Waterman score: 1904; 99.7% identity (100.0% similar) in 292 aa overlap (160-451:7-298) 130 140 150 160 170 180 pF1KB8 DSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSL :::::::::::::::::::::::::::::: XP_011 MEVTVWRYPKKLVQTYSVFPYQDEMSDVVVQPYNSL 10 20 30 190 200 210 220 230 240 pF1KB8 LTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYM 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB8 NNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGR 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB8 DRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB8 AHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDVFKDNFDEMDRSREVVQ :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_011 AHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQ 220 230 240 250 260 270 430 440 450 pF1KB8 ELIDEYHAATQPDYISWGTQEQ :::::::::::::::::::::: XP_011 ELIDEYHAATQPDYISWGTQEQ 280 290 >>XP_016879944 (OMIM: 605785) PREDICTED: tubulin gamma-2 (274 aa) initn: 1780 init1: 1780 opt: 1780 Z-score: 2123.4 bits: 401.4 E(85289): 1.5e-111 Smith-Waterman score: 1780; 99.6% identity (100.0% similar) in 274 aa overlap (178-451:1-274) 150 160 170 180 190 200 pF1KB8 GLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDN :::::::::::::::::::::::::::::: XP_016 MSDVVVQPYNSLLTLKRLTQNADCVVVLDN 10 20 30 210 220 230 240 250 260 pF1KB8 TALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLH 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 FLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGE 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 VDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 FESSCQQFDKLRKRDAFLEQFRKEDVFKDNFDEMDRSREVVQELIDEYHAATQPDYISWG :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: XP_016 FESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQELIDEYHAATQPDYISWG 220 230 240 250 260 270 450 pF1KB8 TQEQ :::: XP_016 TQEQ >>XP_016879945 (OMIM: 605785) PREDICTED: tubulin gamma-2 (274 aa) initn: 1780 init1: 1780 opt: 1780 Z-score: 2123.4 bits: 401.4 E(85289): 1.5e-111 Smith-Waterman score: 1780; 99.6% identity (100.0% similar) in 274 aa overlap (178-451:1-274) 150 160 170 180 190 200 pF1KB8 GLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDN :::::::::::::::::::::::::::::: XP_016 MSDVVVQPYNSLLTLKRLTQNADCVVVLDN 10 20 30 210 220 230 240 250 260 pF1KB8 TALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLH 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 FLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGE 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 VDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 FESSCQQFDKLRKRDAFLEQFRKEDVFKDNFDEMDRSREVVQELIDEYHAATQPDYISWG :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: XP_016 FESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQELIDEYHAATQPDYISWG 220 230 240 250 260 270 450 pF1KB8 TQEQ :::: XP_016 TQEQ >>XP_016879946 (OMIM: 605785) PREDICTED: tubulin gamma-2 (274 aa) initn: 1780 init1: 1780 opt: 1780 Z-score: 2123.4 bits: 401.4 E(85289): 1.5e-111 Smith-Waterman score: 1780; 99.6% identity (100.0% similar) in 274 aa overlap (178-451:1-274) 150 160 170 180 190 200 pF1KB8 GLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDN :::::::::::::::::::::::::::::: XP_016 MSDVVVQPYNSLLTLKRLTQNADCVVVLDN 10 20 30 210 220 230 240 250 260 pF1KB8 TALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLH 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 FLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGE 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 VDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 FESSCQQFDKLRKRDAFLEQFRKEDVFKDNFDEMDRSREVVQELIDEYHAATQPDYISWG :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: XP_016 FESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQELIDEYHAATQPDYISWG 220 230 240 250 260 270 450 pF1KB8 TQEQ :::: XP_016 TQEQ >>XP_016879943 (OMIM: 605785) PREDICTED: tubulin gamma-2 (274 aa) initn: 1780 init1: 1780 opt: 1780 Z-score: 2123.4 bits: 401.4 E(85289): 1.5e-111 Smith-Waterman score: 1780; 99.6% identity (100.0% similar) in 274 aa overlap (178-451:1-274) 150 160 170 180 190 200 pF1KB8 GLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDN :::::::::::::::::::::::::::::: XP_016 MSDVVVQPYNSLLTLKRLTQNADCVVVLDN 10 20 30 210 220 230 240 250 260 pF1KB8 TALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLH 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 FLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGE 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 VDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSL 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 FESSCQQFDKLRKRDAFLEQFRKEDVFKDNFDEMDRSREVVQELIDEYHAATQPDYISWG :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: XP_016 FESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQELIDEYHAATQPDYISWG 220 230 240 250 260 270 450 pF1KB8 TQEQ :::: XP_016 TQEQ >>NP_006079 (OMIM: 602660) tubulin beta-4B chain [Homo s (445 aa) initn: 887 init1: 315 opt: 997 Z-score: 1188.2 bits: 229.1 E(85289): 1.9e-59 Smith-Waterman score: 1001; 34.7% identity (72.0% similar) in 435 aa overlap (3-436:2-423) 10 20 30 40 50 60 pF1KB8 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY :::. :: :::::::: .::. . ::::.: : . . .: .:.. .: .: NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKY 10 20 30 40 50 70 80 90 100 110 pF1KB8 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIF .:::::.:::: .. :. ..:..... :.:. ... .:::::::.: ...: .. .... NP_006 VPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 DIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMS :.. .::.. : :.:: : ::..::::::.:. :. .. ..:: ....:.:: : . ..: NP_006 DVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVP-SPKVS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 DVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAS :.::.:::. :....:..:.: . .:: :: : :.. .:.....:.:::. ::. NP_006 DTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 TTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQ :: ::.:: .: :: : ....: :::::.: :..:::. : . : :: .. ..... NP_006 TTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS-QQYRALTVPELTQQMFD 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 PKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVA ::.:.. : . .. :... ...:... .: ... ..... . :. : : ....: NP_006 AKNMMAAC--DPRHGR-YLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 LSRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDVFKDNFD . : : . ..:. ...: :.:. ::. .:: . .: :::. . : . . .: NP_006 VC-DIP--PRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 360 370 380 390 400 420 430 440 450 pF1KB8 EMDRSREVVQELIDEYHAATQPDYISWGTQEQ : . . ...:..::. NP_006 EAESN---MNDLVSEYQQYQDATAEEEGEFEEEAEEEVA 410 420 430 440 451 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:47:14 2016 done: Fri Nov 4 09:47:15 2016 Total Scan time: 5.790 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]