FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8128, 308 aa 1>>>pF1KB8128 308 - 308 aa - 308 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2029+/-0.000392; mu= 15.5861+/- 0.024 mean_var=61.3166+/-12.650, 0's: 0 Z-trim(111.8): 17 B-trim: 22 in 1/49 Lambda= 0.163789 statistics sampled from 20501 (20510) to 20501 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.24), width: 16 Scan time: 6.080 The best scores are: opt bits E(85289) NP_057714 (OMIM: 248900,608181) maspardin isoform ( 308) 2090 502.6 4.2e-142 XP_005254494 (OMIM: 248900,608181) PREDICTED: masp ( 308) 2090 502.6 4.2e-142 XP_016877786 (OMIM: 248900,608181) PREDICTED: masp ( 308) 2090 502.6 4.2e-142 XP_016877787 (OMIM: 248900,608181) PREDICTED: masp ( 308) 2090 502.6 4.2e-142 NP_001121361 (OMIM: 248900,608181) maspardin isofo ( 308) 2090 502.6 4.2e-142 NP_001121362 (OMIM: 248900,608181) maspardin isofo ( 281) 1362 330.5 2.4e-90 >>NP_057714 (OMIM: 248900,608181) maspardin isoform a [H (308 aa) initn: 2090 init1: 2090 opt: 2090 Z-score: 2672.2 bits: 502.6 E(85289): 4.2e-142 Smith-Waterman score: 2090; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB8 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 250 260 270 280 290 300 pF1KB8 LGISQEEQ :::::::: NP_057 LGISQEEQ >>XP_005254494 (OMIM: 248900,608181) PREDICTED: maspardi (308 aa) initn: 2090 init1: 2090 opt: 2090 Z-score: 2672.2 bits: 502.6 E(85289): 4.2e-142 Smith-Waterman score: 2090; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB8 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 250 260 270 280 290 300 pF1KB8 LGISQEEQ :::::::: XP_005 LGISQEEQ >>XP_016877786 (OMIM: 248900,608181) PREDICTED: maspardi (308 aa) initn: 2090 init1: 2090 opt: 2090 Z-score: 2672.2 bits: 502.6 E(85289): 4.2e-142 Smith-Waterman score: 2090; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB8 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 250 260 270 280 290 300 pF1KB8 LGISQEEQ :::::::: XP_016 LGISQEEQ >>XP_016877787 (OMIM: 248900,608181) PREDICTED: maspardi (308 aa) initn: 2090 init1: 2090 opt: 2090 Z-score: 2672.2 bits: 502.6 E(85289): 4.2e-142 Smith-Waterman score: 2090; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB8 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 250 260 270 280 290 300 pF1KB8 LGISQEEQ :::::::: XP_016 LGISQEEQ >>NP_001121361 (OMIM: 248900,608181) maspardin isoform a (308 aa) initn: 2090 init1: 2090 opt: 2090 Z-score: 2672.2 bits: 502.6 E(85289): 4.2e-142 Smith-Waterman score: 2090; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB8 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 250 260 270 280 290 300 pF1KB8 LGISQEEQ :::::::: NP_001 LGISQEEQ >>NP_001121362 (OMIM: 248900,608181) maspardin isoform b (281 aa) initn: 1362 init1: 1362 opt: 1362 Z-score: 1743.1 bits: 330.5 E(85289): 2.4e-90 Smith-Waterman score: 1822; 91.2% identity (91.2% similar) in 308 aa overlap (1-308:1-281) 10 20 30 40 50 60 pF1KB8 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE ::::::::::::::: :::::::::::::::::: NP_001 RQILALTGWGYRVIA---------------------------VHLFGASLGGFLAQKFAE 70 80 90 130 140 150 160 170 180 pF1KB8 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 220 230 240 250 260 270 pF1KB8 LGISQEEQ :::::::: NP_001 LGISQEEQ 280 308 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:48:09 2016 done: Fri Nov 4 09:48:10 2016 Total Scan time: 6.080 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]