FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8129, 341 aa 1>>>pF1KB8129 341 - 341 aa - 341 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5983+/-0.000353; mu= 10.2453+/- 0.022 mean_var=102.7869+/-19.739, 0's: 0 Z-trim(116.5): 51 B-trim: 116 in 2/54 Lambda= 0.126504 statistics sampled from 27640 (27691) to 27640 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.325), width: 16 Scan time: 5.210 The best scores are: opt bits E(85289) NP_036534 (OMIM: 601638) arfaptin-2 isoform 2 [Hom ( 341) 2216 414.8 1.3e-115 XP_005252897 (OMIM: 601638) PREDICTED: arfaptin-2 ( 341) 2216 414.8 1.3e-115 NP_001229784 (OMIM: 601638) arfaptin-2 isoform 3 [ ( 303) 1963 368.6 9.5e-102 NP_001229783 (OMIM: 601638) arfaptin-2 isoform 1 [ ( 374) 1794 337.8 2.2e-92 NP_001229785 (OMIM: 601638) arfaptin-2 isoform 4 [ ( 256) 1506 285.2 1.1e-76 NP_001020764 (OMIM: 605928) arfaptin-1 isoform 2 [ ( 341) 1358 258.2 1.8e-68 NP_001274362 (OMIM: 605928) arfaptin-1 isoform 2 [ ( 341) 1358 258.2 1.8e-68 NP_055262 (OMIM: 605928) arfaptin-1 isoform 2 [Hom ( 341) 1358 258.2 1.8e-68 XP_011530173 (OMIM: 605928) PREDICTED: arfaptin-1 ( 347) 1329 252.9 7.2e-67 XP_011530174 (OMIM: 605928) PREDICTED: arfaptin-1 ( 296) 1261 240.5 3.5e-63 NP_001020766 (OMIM: 605928) arfaptin-1 isoform 1 [ ( 373) 1261 240.6 4.2e-63 NP_001274360 (OMIM: 605928) arfaptin-1 isoform 1 [ ( 373) 1261 240.6 4.2e-63 NP_001274361 (OMIM: 605928) arfaptin-1 isoform 1 [ ( 373) 1261 240.6 4.2e-63 XP_011530172 (OMIM: 605928) PREDICTED: arfaptin-1 ( 373) 1261 240.6 4.2e-63 XP_011530171 (OMIM: 605928) PREDICTED: arfaptin-1 ( 373) 1261 240.6 4.2e-63 XP_011530170 (OMIM: 605928) PREDICTED: arfaptin-1 ( 379) 1261 240.6 4.2e-63 XP_016884584 (OMIM: 605926) PREDICTED: PRKCA-bindi ( 334) 178 42.9 0.0012 XP_016884579 (OMIM: 605926) PREDICTED: PRKCA-bindi ( 385) 178 42.9 0.0014 XP_016884581 (OMIM: 605926) PREDICTED: PRKCA-bindi ( 385) 178 42.9 0.0014 XP_006724442 (OMIM: 605926) PREDICTED: PRKCA-bindi ( 287) 175 42.3 0.0016 XP_016884582 (OMIM: 605926) PREDICTED: PRKCA-bindi ( 287) 175 42.3 0.0016 XP_016884583 (OMIM: 605926) PREDICTED: PRKCA-bindi ( 287) 175 42.3 0.0016 XP_006724443 (OMIM: 605926) PREDICTED: PRKCA-bindi ( 287) 175 42.3 0.0016 XP_016884580 (OMIM: 605926) PREDICTED: PRKCA-bindi ( 327) 175 42.3 0.0017 NP_001034672 (OMIM: 605926) PRKCA-binding protein ( 415) 175 42.4 0.0021 NP_036539 (OMIM: 605926) PRKCA-binding protein [Ho ( 415) 175 42.4 0.0021 NP_001034673 (OMIM: 605926) PRKCA-binding protein ( 415) 175 42.4 0.0021 >>NP_036534 (OMIM: 601638) arfaptin-2 isoform 2 [Homo sa (341 aa) initn: 2216 init1: 2216 opt: 2216 Z-score: 2196.5 bits: 414.8 E(85289): 1.3e-115 Smith-Waterman score: 2216; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341) 10 20 30 40 50 60 pF1KB8 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLL 250 260 270 280 290 300 310 320 330 340 pF1KB8 FHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ ::::::::::::::::::::::::::::::::::::::::: NP_036 FHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ 310 320 330 340 >>XP_005252897 (OMIM: 601638) PREDICTED: arfaptin-2 isof (341 aa) initn: 2216 init1: 2216 opt: 2216 Z-score: 2196.5 bits: 414.8 E(85289): 1.3e-115 Smith-Waterman score: 2216; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341) 10 20 30 40 50 60 pF1KB8 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLL 250 260 270 280 290 300 310 320 330 340 pF1KB8 FHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ ::::::::::::::::::::::::::::::::::::::::: XP_005 FHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ 310 320 330 340 >>NP_001229784 (OMIM: 601638) arfaptin-2 isoform 3 [Homo (303 aa) initn: 1963 init1: 1963 opt: 1963 Z-score: 1947.7 bits: 368.6 E(85289): 9.5e-102 Smith-Waterman score: 1963; 100.0% identity (100.0% similar) in 303 aa overlap (39-341:1-303) 10 20 30 40 50 60 pF1KB8 AATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSG :::::::::::::::::::::::::::::: NP_001 MVSGPNLNETSIVSGGYGGSGDGLIPTGSG 10 20 30 70 80 90 100 110 120 pF1KB8 RHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELEL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 QIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAET 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 QKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 PRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAY 220 230 240 250 260 270 310 320 330 340 pF1KB8 FAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ ::::::::::::::::::::::::::::::::: NP_001 FAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ 280 290 300 >>NP_001229783 (OMIM: 601638) arfaptin-2 isoform 1 [Homo (374 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 1779.6 bits: 337.8 E(85289): 2.2e-92 Smith-Waterman score: 2133; 91.2% identity (91.2% similar) in 373 aa overlap (2-341:2-374) 10 20 30 40 50 60 pF1KB8 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD 10 20 30 40 50 60 70 80 pF1KB8 GLIPTG---------------------------------SGRHPSHSTTPSGPGDEVARG :::::: ::::::::::::::::::::: NP_001 GLIPTGKSISCARREVWVGPQRCLVYLREAGVRELDPLGSGRHPSHSTTPSGPGDEVARG 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB8 IAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLG 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB8 RALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFV 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB8 SSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQA 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB8 HRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKL 310 320 330 340 350 360 330 340 pF1KB8 RPPGAEKPSWLEEQ :::::::::::::: NP_001 RPPGAEKPSWLEEQ 370 >>NP_001229785 (OMIM: 601638) arfaptin-2 isoform 4 [Homo (256 aa) initn: 1506 init1: 1506 opt: 1506 Z-score: 1498.0 bits: 285.2 E(85289): 1.1e-76 Smith-Waterman score: 1506; 99.6% identity (100.0% similar) in 237 aa overlap (105-341:20-256) 80 90 100 110 120 130 pF1KB8 TTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLR .::::::::::::::::::::::::::::: NP_001 MKPALCLVAMGALVMDSSPQCTKQLLSERFGRGSRTVDLELELQIELLR 10 20 30 40 140 150 160 170 180 190 pF1KB8 ETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCK 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB8 NGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGT 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB8 RGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQK 170 180 190 200 210 220 320 330 340 pF1KB8 QLEQTLQQFNIKLRPPGAEKPSWLEEQ ::::::::::::::::::::::::::: NP_001 QLEQTLQQFNIKLRPPGAEKPSWLEEQ 230 240 250 >>NP_001020764 (OMIM: 605928) arfaptin-1 isoform 2 [Homo (341 aa) initn: 1355 init1: 1227 opt: 1358 Z-score: 1350.2 bits: 258.2 E(85289): 1.8e-68 Smith-Waterman score: 1358; 59.9% identity (89.3% similar) in 337 aa overlap (8-341:7-341) 10 20 30 40 50 60 pF1KB8 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD : .. :::. .:::. . .. ....::.. . :: .:.::.:.: :. .. . NP_001 MAQESPKNSAAEIPVTSNGEVDD-SREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKE 10 20 30 40 50 70 80 90 100 110 pF1KB8 GLIPTGSGRHPSHSTTPSGP---GDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGR :.: .:. . ... : ::: .::. .. : ::...:.::..::::::.:..::..:: NP_001 GVIEAGAFQGGQRTQTKSGPVILADEI-KNPAMEKLELVRKWSLNTYKCTRQIISEKLGR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 GSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPE :::::::::: ::..::..:.:::..:.:...:...:.....::. ::::::::: :: : NP_001 GSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDA :.:::::::.::::: :::::::::.:::..:.::::.::.:::::::::::.::.:::: NP_001 LHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 YRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQ ::::::::.::::::.: ..:..: ::::..::.:.:.::..:::::::::.::.:.: NP_001 YRTDLEELNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQ 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 LLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ :.:::::..::::::::::::::.::.:::. ::.. ::::::: NP_001 LVLFHNAIAAYFAGNQKQLEQTLKQFHIKLKTPGVDAPSWLEEQ 300 310 320 330 340 >>NP_001274362 (OMIM: 605928) arfaptin-1 isoform 2 [Homo (341 aa) initn: 1355 init1: 1227 opt: 1358 Z-score: 1350.2 bits: 258.2 E(85289): 1.8e-68 Smith-Waterman score: 1358; 59.9% identity (89.3% similar) in 337 aa overlap (8-341:7-341) 10 20 30 40 50 60 pF1KB8 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD : .. :::. .:::. . .. ....::.. . :: .:.::.:.: :. .. . NP_001 MAQESPKNSAAEIPVTSNGEVDD-SREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKE 10 20 30 40 50 70 80 90 100 110 pF1KB8 GLIPTGSGRHPSHSTTPSGP---GDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGR :.: .:. . ... : ::: .::. .. : ::...:.::..::::::.:..::..:: NP_001 GVIEAGAFQGGQRTQTKSGPVILADEI-KNPAMEKLELVRKWSLNTYKCTRQIISEKLGR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 GSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPE :::::::::: ::..::..:.:::..:.:...:...:.....::. ::::::::: :: : NP_001 GSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDA :.:::::::.::::: :::::::::.:::..:.::::.::.:::::::::::.::.:::: NP_001 LHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 YRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQ ::::::::.::::::.: ..:..: ::::..::.:.:.::..:::::::::.::.:.: NP_001 YRTDLEELNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQ 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 LLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ :.:::::..::::::::::::::.::.:::. ::.. ::::::: NP_001 LVLFHNAIAAYFAGNQKQLEQTLKQFHIKLKTPGVDAPSWLEEQ 300 310 320 330 340 >>NP_055262 (OMIM: 605928) arfaptin-1 isoform 2 [Homo sa (341 aa) initn: 1355 init1: 1227 opt: 1358 Z-score: 1350.2 bits: 258.2 E(85289): 1.8e-68 Smith-Waterman score: 1358; 59.9% identity (89.3% similar) in 337 aa overlap (8-341:7-341) 10 20 30 40 50 60 pF1KB8 MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD : .. :::. .:::. . .. ....::.. . :: .:.::.:.: :. .. . NP_055 MAQESPKNSAAEIPVTSNGEVDD-SREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKE 10 20 30 40 50 70 80 90 100 110 pF1KB8 GLIPTGSGRHPSHSTTPSGP---GDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGR :.: .:. . ... : ::: .::. .. : ::...:.::..::::::.:..::..:: NP_055 GVIEAGAFQGGQRTQTKSGPVILADEI-KNPAMEKLELVRKWSLNTYKCTRQIISEKLGR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 GSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPE :::::::::: ::..::..:.:::..:.:...:...:.....::. ::::::::: :: : NP_055 GSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDA :.:::::::.::::: :::::::::.:::..:.::::.::.:::::::::::.::.:::: NP_055 LHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 YRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQ ::::::::.::::::.: ..:..: ::::..::.:.:.::..:::::::::.::.:.: NP_055 YRTDLEELNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQ 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 LLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ :.:::::..::::::::::::::.::.:::. ::.. ::::::: NP_055 LVLFHNAIAAYFAGNQKQLEQTLKQFHIKLKTPGVDAPSWLEEQ 300 310 320 330 340 >>XP_011530173 (OMIM: 605928) PREDICTED: arfaptin-1 isof (347 aa) initn: 1325 init1: 1227 opt: 1329 Z-score: 1321.5 bits: 252.9 E(85289): 7.2e-67 Smith-Waterman score: 1329; 62.6% identity (90.7% similar) in 313 aa overlap (32-341:36-347) 10 20 30 40 50 60 pF1KB8 TDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDG :.::.. . :: .:.::.:.: :. .. .: XP_011 PRFKKKKRITIFGEISWTPAIGSILVPVHQEKDLKHSLPSGLGLSETQITSHGFDNTKEG 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LIPTGSGRHPSHSTTPSGP---GDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRG .: .:. . ... : ::: .::. .. : ::...:.::..::::::.:..::..::: XP_011 VIEAGAFQGGQRTQTKSGPVILADEI-KNPAMEKLELVRKWSLNTYKCTRQIISEKLGRG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 SRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPEL ::::::::: ::..::..:.:::..:.:...:...:.....::. ::::::::: :: :: XP_011 SRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLEL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 QEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAY .:::::::.::::: :::::::::.:::..:.::::.::.:::::::::::.::.::::: XP_011 HEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 RTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQL :::::::.::::::.: ..:..: ::::..::.:.:.::..:::::::::.::.:.:: XP_011 RTDLEELNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQL 250 260 270 280 290 300 300 310 320 330 340 pF1KB8 LLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ .:::::..::::::::::::::.::.:::. ::.. ::::::: XP_011 VLFHNAIAAYFAGNQKQLEQTLKQFHIKLKTPGVDAPSWLEEQ 310 320 330 340 >>XP_011530174 (OMIM: 605928) PREDICTED: arfaptin-1 isof (296 aa) initn: 1227 init1: 1227 opt: 1261 Z-score: 1255.4 bits: 240.5 E(85289): 3.5e-63 Smith-Waterman score: 1261; 65.3% identity (91.0% similar) in 288 aa overlap (57-341:15-296) 30 40 50 60 70 80 pF1KB8 EDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTTPSGP---GDE :: : ..:.:. : . : ::: .:: XP_011 MSPSRVAASRLAQQGS-DLIVPAGGQR----TQTKSGPVILADE 10 20 30 90 100 110 120 130 140 pF1KB8 VARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESV . .. : ::...:.::..::::::.:..::..:::::::::::: ::..::..:.:::.. XP_011 I-KNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENI 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB8 LQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAV :.:...:...:.....::. ::::::::: :: ::.:::::::.::::: :::::::::. XP_011 LKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAI 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB8 NFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQA :::..:.::::.::.:::::::::::.::.::::::::::::.::::::.: ..:..: XP_011 NFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQH 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB8 TFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQF ::::..::.:.:.::..:::::::::.::.:.::.:::::..::::::::::::::.:: XP_011 LFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQF 220 230 240 250 260 270 330 340 pF1KB8 NIKLRPPGAEKPSWLEEQ .:::. ::.. ::::::: XP_011 HIKLKTPGVDAPSWLEEQ 280 290 341 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:48:38 2016 done: Fri Nov 4 09:48:39 2016 Total Scan time: 5.210 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]