FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8137, 345 aa 1>>>pF1KB8137 345 - 345 aa - 345 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1759+/-0.000739; mu= 12.9944+/- 0.045 mean_var=90.4879+/-17.974, 0's: 0 Z-trim(111.0): 9 B-trim: 0 in 0/53 Lambda= 0.134828 statistics sampled from 12029 (12036) to 12029 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.37), width: 16 Scan time: 1.770 The best scores are: opt bits E(32554) CCDS77902.1 LDB2 gene_id:9079|Hs108|chr4 ( 313) 1245 251.7 5.9e-67 CCDS47031.1 LDB2 gene_id:9079|Hs108|chr4 ( 331) 1245 251.7 6.1e-67 CCDS77903.1 LDB2 gene_id:9079|Hs108|chr4 ( 371) 1245 251.8 6.7e-67 CCDS3420.1 LDB2 gene_id:9079|Hs108|chr4 ( 373) 1245 251.8 6.8e-67 CCDS7528.1 LDB1 gene_id:8861|Hs108|chr10 ( 375) 905 185.6 5.5e-47 CCDS44472.1 LDB1 gene_id:8861|Hs108|chr10 ( 411) 905 185.7 6e-47 >>CCDS77902.1 LDB2 gene_id:9079|Hs108|chr4 (313 aa) initn: 1307 init1: 1235 opt: 1245 Z-score: 1315.6 bits: 251.7 E(32554): 5.9e-67 Smith-Waterman score: 1778; 88.5% identity (89.5% similar) in 305 aa overlap (1-277:1-305) 10 20 30 40 50 60 pF1KB8 MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSITVDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSITVDC 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 DQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMH--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMHAQD 130 140 150 160 170 180 180 190 200 210 pF1KB8 -------------------------LCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQ ::::::::::::::::::::::::::::::::::: CCDS77 PQVLDQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQ 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 RMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVPDVM ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: . CCDS77 RMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVPIAS 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 VVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDDEEDFNNSPALGNNSPWNSKPPATQ .. : CCDS77 IARSPVSGCALRT 310 >>CCDS47031.1 LDB2 gene_id:9079|Hs108|chr4 (331 aa) initn: 1307 init1: 1235 opt: 1245 Z-score: 1315.2 bits: 251.7 E(32554): 6.1e-67 Smith-Waterman score: 1791; 86.9% identity (88.9% similar) in 314 aa overlap (1-286:1-314) 10 20 30 40 50 60 pF1KB8 MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSITVDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSITVDC 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 DQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMH--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMHAQD 130 140 150 160 170 180 180 190 200 210 pF1KB8 -------------------------LCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQ ::::::::::::::::::::::::::::::::::: CCDS47 PQVLDQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQ 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 RMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVPDVM ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: . CCDS47 RMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVPGLG 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 VVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDDEEDFNNSPALGNNSPWNSKPPATQ .. . .: :. :: CCDS47 AIPNCSLNPGRDGDLCHSTAVTPSGQFKEKH 310 320 330 >>CCDS77903.1 LDB2 gene_id:9079|Hs108|chr4 (371 aa) initn: 1749 init1: 1235 opt: 1245 Z-score: 1314.5 bits: 251.8 E(32554): 6.7e-67 Smith-Waterman score: 2268; 92.0% identity (92.0% similar) in 373 aa overlap (1-345:1-371) 10 20 30 40 50 60 pF1KB8 MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSITVDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSITVDC 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 DQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMH--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMHAQD 130 140 150 160 170 180 180 190 200 210 pF1KB8 -------------------------LCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQ ::::::::::::::::::::::::::::::::::: CCDS77 PQVLDQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQ 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 RMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVPDVM ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: CCDS77 RMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQ--DVM 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 VVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDDEEDFNNSPALGNNSPWNSKPPATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDDEEDFNNSPALGNNSPWNSKPPATQ 300 310 320 330 340 350 340 pF1KB8 ETKSENPPPQASQ ::::::::::::: CCDS77 ETKSENPPPQASQ 360 370 >>CCDS3420.1 LDB2 gene_id:9079|Hs108|chr4 (373 aa) initn: 1235 init1: 1235 opt: 1245 Z-score: 1314.5 bits: 251.8 E(32554): 6.8e-67 Smith-Waterman score: 2297; 92.5% identity (92.5% similar) in 373 aa overlap (1-345:1-373) 10 20 30 40 50 60 pF1KB8 MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSITVDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSITVDC 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 DQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMH--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMHAQD 130 140 150 160 170 180 180 190 200 210 pF1KB8 -------------------------LCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQ ::::::::::::::::::::::::::::::::::: CCDS34 PQVLDQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQ 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 RMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVPDVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVPDVM 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 VVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDDEEDFNNSPALGNNSPWNSKPPATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDDEEDFNNSPALGNNSPWNSKPPATQ 310 320 330 340 350 360 340 pF1KB8 ETKSENPPPQASQ ::::::::::::: CCDS34 ETKSENPPPQASQ 370 >>CCDS7528.1 LDB1 gene_id:8861|Hs108|chr10 (375 aa) initn: 1465 init1: 892 opt: 905 Z-score: 957.0 bits: 185.6 E(32554): 5.5e-47 Smith-Waterman score: 1766; 70.6% identity (84.2% similar) in 367 aa overlap (8-345:10-375) 10 20 30 40 50 pF1KB8 MSSTPHDPFYSSPF-GPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATE :.: . : ::::: : .:::.:.:::::. ::. ::::::::.:: CCDS75 MLDRDVGPTPMYPPTYLEPGIGRHTPYGNQTDYRIFELNKRLQNWTEECDNLWWDAFTTE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 FFEDDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSIT :::::: ::..::::::::::::::::::::: ..::::.:.:::.::: ::..:.. .. CCDS75 FFEDDAMLTITFCLEDGPKRYTIGRTLIPRYFRSIFEGGATELYYVLKHPKEAFHSNFVS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 VDCDQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMH .:::: .:::::::::::.::.:::: ::: :::.::::::::.:::.:::.:::::::: CCDS75 LDCDQGSMVTQHGKPMFTQVCVEGRLYLEFMFDDMMRIKTWHFSIRQHRELIPRSILAMH 130 140 150 160 170 180 180 190 200 pF1KB8 ----------------------------LCVILEPMQELMSRHKTYNLSPRDCLKTCLFQ ::::::::::::::::::.::::::::::::: CCDS75 AQDPQMLDQLSKNITRCGLSNSTLNYLRLCVILEPMQELMSRHKTYSLSPRDCLKTCLFQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB8 KWQRMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVP ::::::::::::::: .:::::: : .:: ::.:.:.:...::::. :....:::::: CCDS75 KWQRMVAPPAEPTRQQPSKRRKRKMSGGSTM-SSGGGNTNNSNSKKKSPASTFALSSQVP 250 260 270 280 290 270 280 290 300 310 320 pF1KB8 DVMVVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDDEEDFNNSPALGNNSPWNSKPP ::::::::::::::::::::::::::::::.:::::.:::..:::::::: ::::::::: CCDS75 DVMVVGEPTLMGGEFGDEDERLITRLENTQFDAANGIDDEDSFNNSPALGANSPWNSKPP 300 310 320 330 340 350 330 340 pF1KB8 ATQETKSENPPPQASQ ..::.::::: :::: CCDS75 SSQESKSENPTSQASQ 360 370 >>CCDS44472.1 LDB1 gene_id:8861|Hs108|chr10 (411 aa) initn: 1465 init1: 892 opt: 905 Z-score: 956.4 bits: 185.7 E(32554): 6e-47 Smith-Waterman score: 1766; 70.6% identity (84.2% similar) in 367 aa overlap (8-345:46-411) 10 20 30 pF1KB8 MSSTPHDPFYSSPF-GPFYRRHTPYMVQPEYRIYEMN :.: . : ::::: : .:::.:.: CCDS44 KLYSPKEPPNGNAFPPFHPGTMLDRDVGPTPMYPPTYLEPGIGRHTPYGNQTDYRIFELN 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 KRLQSRTEDSDNLWWDAFATEFFEDDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGG ::::. ::. ::::::::.:::::::: ::..::::::::::::::::::::: ..:::: CCDS44 KRLQNWTEECDNLWWDAFTTEFFEDDAMLTITFCLEDGPKRYTIGRTLIPRYFRSIFEGG 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 VTDLYYILKHSKESYHNSSITVDCDQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIK .:.:::.::: ::..:.. ...:::: .:::::::::::.::.:::: ::: :::.:::: CCDS44 ATELYYVLKHPKEAFHSNFVSLDCDQGSMVTQHGKPMFTQVCVEGRLYLEFMFDDMMRIK 140 150 160 170 180 190 160 170 180 pF1KB8 TWHFTIRQYRELVPRSILAMH----------------------------LCVILEPMQEL ::::.:::.:::.:::::::: ::::::::::: CCDS44 TWHFSIRQHRELIPRSILAMHAQDPQMLDQLSKNITRCGLSNSTLNYLRLCVILEPMQEL 200 210 220 230 240 250 190 200 210 220 230 240 pF1KB8 MSRHKTYNLSPRDCLKTCLFQKWQRMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNA :::::::.:::::::::::::::::::::::::::: .:::::: : .:: ::.:.:. CCDS44 MSRHKTYSLSPRDCLKTCLFQKWQRMVAPPAEPTRQQPSKRRKRKMSGGSTM-SSGGGNT 260 270 280 290 300 310 250 260 270 280 290 300 pF1KB8 NSTGSKKKTTAANLSLSSQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDD :...::::. :....::::::::::::::::::::::::::::::::::::.:::::.:: CCDS44 NNSNSKKKSPASTFALSSQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQFDAANGIDD 320 330 340 350 360 370 310 320 330 340 pF1KB8 EEDFNNSPALGNNSPWNSKPPATQETKSENPPPQASQ :..:::::::: :::::::::..::.::::: :::: CCDS44 EDSFNNSPALGANSPWNSKPPSSQESKSENPTSQASQ 380 390 400 410 345 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:52:58 2016 done: Fri Nov 4 09:52:58 2016 Total Scan time: 1.770 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]