Result of FASTA (omim) for
pF1KB8138
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8138, 593 aa
1>>>pF1KB8138 593 - 593 aa - 593 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4132+/-0.000495; mu= 15.5096+/- 0.031
mean_var=187.1599+/-36.502, 0's: 0 Z-trim(116.4): 220 B-trim: 154 in 1/54
Lambda= 0.093749
statistics sampled from 27177 (27461) to 27177 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.322), width: 16
Scan time: 8.970
The best scores are: opt bits E(85289)
XP_005257310 (OMIM: 138945,607485,614706) PREDICTE ( 593) 4654 642.7 1e-183
NP_002078 (OMIM: 138945,607485,614706) granulins p ( 593) 4654 642.7 1e-183
XP_011539190 (OMIM: 604266) PREDICTED: multiple ep (1364) 339 59.6 8e-08
NP_004548 (OMIM: 164951) neurogenic locus notch ho (2003) 334 59.1 1.6e-07
NP_955381 (OMIM: 609344) kielin/chordin-like prote ( 814) 319 56.6 3.8e-07
XP_016867681 (OMIM: 609344) PREDICTED: kielin/chor (1347) 322 57.3 3.9e-07
XP_016867680 (OMIM: 609344) PREDICTED: kielin/chor (1347) 322 57.3 3.9e-07
XP_016867683 (OMIM: 609344) PREDICTED: kielin/chor (1093) 318 56.6 5e-07
XP_016867682 (OMIM: 609344) PREDICTED: kielin/chor (1102) 318 56.6 5e-07
XP_016867679 (OMIM: 609344) PREDICTED: kielin/chor (1466) 318 56.8 6e-07
XP_016867678 (OMIM: 609344) PREDICTED: kielin/chor (1526) 318 56.8 6.1e-07
XP_016867677 (OMIM: 609344) PREDICTED: kielin/chor (1555) 318 56.8 6.2e-07
XP_016867675 (OMIM: 609344) PREDICTED: kielin/chor (1615) 318 56.8 6.3e-07
XP_016867676 (OMIM: 609344) PREDICTED: kielin/chor (1615) 318 56.8 6.3e-07
XP_016867674 (OMIM: 609344) PREDICTED: kielin/chor (1628) 318 56.8 6.4e-07
XP_016867673 (OMIM: 609344) PREDICTED: kielin/chor (1633) 318 56.8 6.4e-07
NP_001129386 (OMIM: 609344) kielin/chordin-like pr (1503) 313 56.1 9.7e-07
NP_660142 (OMIM: 602570) protein jagged-2 isoform (1200) 306 55.0 1.6e-06
XP_016859265 (OMIM: 616634) PREDICTED: sushi, nido (1420) 280 51.6 2.1e-05
XP_011507814 (OMIM: 610278) PREDICTED: platelet en ( 868) 276 50.8 2.2e-05
XP_016856731 (OMIM: 610278) PREDICTED: platelet en ( 909) 276 50.8 2.3e-05
XP_016856729 (OMIM: 610278) PREDICTED: platelet en ( 909) 276 50.8 2.3e-05
XP_016856730 (OMIM: 610278) PREDICTED: platelet en ( 909) 276 50.8 2.3e-05
XP_016856728 (OMIM: 610278) PREDICTED: platelet en ( 973) 276 50.9 2.4e-05
XP_016856727 (OMIM: 610278) PREDICTED: platelet en ( 973) 276 50.9 2.4e-05
XP_016856726 (OMIM: 610278) PREDICTED: platelet en ( 973) 276 50.9 2.4e-05
XP_011507813 (OMIM: 610278) PREDICTED: platelet en (1002) 276 50.9 2.4e-05
XP_005245198 (OMIM: 610278) PREDICTED: platelet en (1037) 276 50.9 2.5e-05
NP_001073940 (OMIM: 610278) platelet endothelial a (1037) 276 50.9 2.5e-05
XP_011507812 (OMIM: 610278) PREDICTED: platelet en (1037) 276 50.9 2.5e-05
XP_016856725 (OMIM: 610278) PREDICTED: platelet en (1037) 276 50.9 2.5e-05
XP_016856724 (OMIM: 610278) PREDICTED: platelet en (1081) 276 50.9 2.5e-05
XP_016856723 (OMIM: 610278) PREDICTED: platelet en (1125) 276 51.0 2.6e-05
XP_005259981 (OMIM: 125310,130720,600276,615293) P (2269) 278 51.6 3.3e-05
NP_000426 (OMIM: 125310,130720,600276,615293) neur (2321) 278 51.6 3.3e-05
NP_001138581 (OMIM: 602320) protein kinase C-bindi ( 815) 267 49.6 5e-05
NP_006150 (OMIM: 602320) protein kinase C-binding ( 816) 267 49.6 5e-05
XP_011536698 (OMIM: 602320) PREDICTED: protein kin ( 816) 267 49.6 5e-05
NP_001138580 (OMIM: 602320) protein kinase C-bindi ( 816) 267 49.6 5e-05
XP_005268962 (OMIM: 602320) PREDICTED: protein kin ( 816) 267 49.6 5e-05
XP_016859267 (OMIM: 616634) PREDICTED: sushi, nido (1309) 270 50.2 5e-05
XP_016859268 (OMIM: 616634) PREDICTED: sushi, nido (1309) 270 50.2 5e-05
XP_016859270 (OMIM: 616634) PREDICTED: sushi, nido (1309) 270 50.2 5e-05
XP_016859269 (OMIM: 616634) PREDICTED: sushi, nido (1309) 270 50.2 5e-05
XP_016874832 (OMIM: 602320) PREDICTED: protein kin ( 821) 267 49.6 5e-05
XP_016874833 (OMIM: 602320) PREDICTED: protein kin ( 821) 267 49.6 5e-05
XP_016874831 (OMIM: 602320) PREDICTED: protein kin ( 821) 267 49.6 5e-05
XP_011509236 (OMIM: 616634) PREDICTED: sushi, nido (1315) 270 50.2 5e-05
NP_001138582 (OMIM: 602320) protein kinase C-bindi ( 839) 267 49.6 5.1e-05
XP_011509235 (OMIM: 616634) PREDICTED: sushi, nido (1351) 270 50.2 5.1e-05
>>XP_005257310 (OMIM: 138945,607485,614706) PREDICTED: g (593 aa)
initn: 4654 init1: 4654 opt: 4654 Z-score: 3419.5 bits: 642.7 E(85289): 1e-183
Smith-Waterman score: 4654; 100.0% identity (100.0% similar) in 593 aa overlap (1-593:1-593)
10 20 30 40 50 60
pF1KB8 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 SGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 KRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 EIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQG
490 500 510 520 530 540
550 560 570 580 590
pF1KB8 WACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL
550 560 570 580 590
>>NP_002078 (OMIM: 138945,607485,614706) granulins precu (593 aa)
initn: 4654 init1: 4654 opt: 4654 Z-score: 3419.5 bits: 642.7 E(85289): 1e-183
Smith-Waterman score: 4654; 100.0% identity (100.0% similar) in 593 aa overlap (1-593:1-593)
10 20 30 40 50 60
pF1KB8 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 SGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 KRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 EIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQG
490 500 510 520 530 540
550 560 570 580 590
pF1KB8 WACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL
550 560 570 580 590
>>XP_011539190 (OMIM: 604266) PREDICTED: multiple epider (1364 aa)
initn: 162 init1: 90 opt: 339 Z-score: 261.5 bits: 59.6 E(85289): 8e-08
Smith-Waterman score: 418; 24.0% identity (44.6% similar) in 597 aa overlap (20-560:589-1140)
10 20 30 40
pF1KB8 MWTLVSWVALTAGLVAGTRCPDGQFCPVAC--CLDPGGASYSCCRPLLD
: .: : .. : : : . :
XP_011 AELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCP
560 570 580 590 600 610
50 60 70 80 90 100
pF1KB8 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSA
: :.... :. . :. : .: .:.:. : : .. : :: ::.:..
XP_011 --PDTFGKN----CSFSCSCQNGGTCD-SVTGACRCPPGVSGTNCEDG---CPKGYY---
620 630 640 650 660
110 120 130 140 150 160
pF1KB8 DGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWG--C---CPMPQA--SCCED
:. : .. . . : .: . :. : .: : :: : : : .
XP_011 -GKHCRKKCNCANRG---------RCHRLYGACLCDPGLYGRFCHLTCP-PWAFGPGCSE
670 680 690 700 710
170 180 190 200 210
pF1KB8 RVHCC-PHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGS
. .: :: :: : .: . . . . . .. :: . . : . :
XP_011 ECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVA-CDSVS
720 730 740 750 760 770
220 230 240 250 260 270
pF1KB8 TCC--ELPSGKYG--C---CPMPN-ATCCSDHLHCCPQDTVCDLIQSKCLSKENAT-TDL
: . :.: : : ::. . .. ::. : . : . ..: . : :
XP_011 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC--GGAPCHGVTGQCRCPPGRTGEDC
780 790 800 810 820 830
280 290 300 310 320
pF1KB8 LTKLPAHTVGDVKCDMEVSCP--DGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGF--
. : : . :. :. :: . . : ..:: : : . :.: ::::.
XP_011 EADCPEGRWG-LGCQ-EI-CPACQHAARCDPETGACLCLPGFVGSRCQD---VCPAGWYG
840 850 860 870 880
330 340 350 360 370 380
pF1KB8 -TCDTQKGTCEQGPHQVPWMEKAPAHLSL-PDPQALKRDVPCDNVSSCPSSDTCCQLTSG
.:.: . .: . : : : .: : : ... . ::. :. . :. ..:
XP_011 PSCQT-RCSCANDGHCHP----ATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAG
890 900 910 920 930 940
390 400 410 420 430
pF1KB8 EWGCCPIPEAVCCSDHQH----C---CPQGYT---CVAEGQCQRGS--EIVAGLEKMPA-
. : : ..: . . : ::::. : . :::.:. . :.: ::
XP_011 H-GSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG
950 960 970 980 990
440 450 460 470
pF1KB8 -RRASLSHPRDIG-----CDQHTSCPVGQTC--------CPSLGGSWACCQL-P-HAVCC
: . : : : . .: .: .: ::. . : . : :.
XP_011 WRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGH
1000 1010 1020 1030 1040 1050
480 490 500 510 520 530
pF1KB8 EDRQHC-CPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCC
. : : : : .:. .:. :. . : : .:. .: .. .:... ::
XP_011 NCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQA-CP-AGLYGDNCRHSCLCQNGGTC-
1060 1070 1080 1090 1100 1110
540 550 560 570 580 590
pF1KB8 RDNRQGWACCPYRQ-GVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL
: .: :: :. : ...: :
XP_011 -DPVSGHCACPEGWAGLAC--EKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWT
1120 1130 1140 1150 1160 1170
>>NP_004548 (OMIM: 164951) neurogenic locus notch homolo (2003 aa)
initn: 147 init1: 76 opt: 334 Z-score: 256.0 bits: 59.1 E(85289): 1.6e-07
Smith-Waterman score: 432; 25.2% identity (44.6% similar) in 643 aa overlap (20-581:359-961)
10 20 30 40
pF1KB8 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSC-CRPLLDK
: . : . :.: : :.:: : :
NP_004 GGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVG-SFSCLCPPGRTG
330 340 350 360 370 380
50 60 70 80 90 100
pF1KB8 WPTTLSRH-LGGPCQVDAHCSAGHSCIFTVSGTSSC-C-PFPEAVACGDGHHCC---PRG
: :. ::. ::.::.. ..:.. : : : . .: . : .:
NP_004 LLCHLEDMCLSQPCHGDAQCSTN-----PLTGSTLCLCQPGYSGPTCHQDLDECLMAQQG
390 400 410 420 430 440
110 120 130 140 150
pF1KB8 FHCSADGRSCFQRSGNNSVGAIQCPDSQF--ECP-DFSTCCVMVDGSWGCCPMPQASCCE
: ::.. : : . . :: . .: : . : : : : .: :
NP_004 PSPCEHGGSCLNTPG--SFNCL-CPPGYTGSRCEADHNECL-----SQPCHP---GSTCL
450 460 470 480 490
160 170 180 190 200 210
pF1KB8 DRV---HC-CP---HGAFCDLVHTRCIT-PTGTHPLAKKLPAQRTNRAVALSSSVMCPD-
: . :: :: .: .:.. ..: . : .: . : . :.. : .
NP_004 DLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEED
500 510 520 530 540 550
220 230 240 250
pF1KB8 ---ARSR-CPDGSTCCELPSGKYGCCPMPN---ATCCSDHLHC----CPQDTVC-DLIQS
:: : .:. : . : : . : .:. : .. .: :: . : :: .
NP_004 IDECRSSPCANGGQCQDQP-GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA
560 570 580 590 600 610
260 270 280 290 300 310
pF1KB8 K-CLSKENATTDLLTKLPAHTVGDVKCDMEVSCPD--GYTCCRLQSGAWGCCPFTQAVCC
:: .. : : ..: . :. . : : . : .:. :: : . :
NP_004 FFCLCP-SGFTGQLCEVP--LCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTC
620 630 640 650 660
320 330 340 350 360
pF1KB8 EDHIHC------CPAGFT---CDTQKGTCEQGP--HQVPWMEKAPAHLSLPDPQALKRDV
. : :: : .:.: :... : : ..: : . . :. . : . .
NP_004 H-HGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ-PSGYNCTCPTGYTGPT
670 680 690 700 710 720
370 380 390 400 410
pF1KB8 PCDNVSSCPSSDTC-----CQLTSGEWGC-CPIPEAV---CCSDHQHC----CPQGYTCV
.....: : : :. . : . : :: : . : .. ..: : .: :::
NP_004 CSEEMTAC-HSGPCLNGGSCNPSPGGYYCTCP-PSHTGPQCQTSTDYCVSAPCFNGGTCV
730 740 750 760 770 780
420 430 440 450 460
pF1KB8 AEGQCQRGSEIVAGLEKMPARRASLSHPR--DIGCDQHTSC---PVGQTC-CPSLGGSWA
.. : . : . : ...: .: : : ....: : : : ::. : . .
NP_004 --NRPGTFSCLCAMGFQGPRCEGKL-RPSCADSPCRNRATCQDSPQGPRCLCPT-GYTGG
790 800 810 820 830
470 480 490 500
pF1KB8 CCQLPHAVC----CEDRQHC----------CPAGYT---CNVKARSCEKEVVSAQPATFL
:: .: : .:: : :.: ::. ::.: ..: . .
NP_004 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALS--QGIDV
840 850 860 870 880 890
510 520 530 540 550 560
pF1KB8 ARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAAR
. : : :. : ..::: : . :: : . . : .: : : : :.
NP_004 SSLCHNGGLCVDSGPSYFCH-----CPPGFQGSLCQDHVNP--CESRP--CQNGATCMAQ
900 910 920 930 940
570 580 590
pF1KB8 GTKCLRREAPRWDAPLRDPALRQLL
. : . :: .:
NP_004 PSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVD
950 960 970 980 990 1000
>>NP_955381 (OMIM: 609344) kielin/chordin-like protein i (814 aa)
initn: 167 init1: 70 opt: 319 Z-score: 249.3 bits: 56.6 E(85289): 3.8e-07
Smith-Waterman score: 441; 26.4% identity (40.7% similar) in 644 aa overlap (19-581:228-808)
10 20 30 40
pF1KB8 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSC--CRPLL
.:: . :: : :: .: :
NP_955 LYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSP-CPEPV-LRPGHCCPTCQGCTEGG
200 210 220 230 240 250
50 60 70 80 90 100
pF1KB8 DKWPTTLSRHL-GGPCQVDAHCSAGH-SCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFH
..: : ::.. .: :: .: .: ::.: : :::
NP_955 SHWEHGQEWTTPGDPCRI-CRCLEGHIQC--RQRECASLCPYPARPLPGT---CCPVCDG
260 270 280 290 300
110 120 130 140
pF1KB8 CSADGRSCFQRSGNN------------SVGAIQCPDSQFECPDF---------STCCVMV
: .:: .:::. . :..:: . :: . :: .
NP_955 CFLNGRE--HRSGEPVGSGDPCSHCRCANGSVQCE--PLPCPPVPCRHPGKIPGQCCPVC
310 320 330 340 350 360
150 160 170 180 190
pF1KB8 DGS--WGCCPMPQASC-CEDR---VHC-CPHGAF-CDLVHTRC-ITPTGTHPLAKKL-PA
:: : . : . ..: :.: : : :. . .: .:: . ...: ::
NP_955 DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE--EQECPVTPCALPASGRQLCPA
370 380 390 400 410 420
200 210 220 230 240
pF1KB8 QRTNRAVALSSSVMCPDARS----RCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQ
. . . ::.: : :: : : : : : . :::.
NP_955 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKC----GAVLCPPAPCQHPTQPPGACCPS
430 440 450 460 470
250 260 270 280 290 300
pF1KB8 DTVCDLIQSKCLSKENATTDLLTKLPAHTV----GDVKCDMEVSCPDGYTCCRLQSGAWG
: .:. .. . :: . : :. : : :.. :.:: :: : :::
NP_955 CDSCTY-HSQVYANGQNFTDADS--PCHACHCQDGTVTCSL-VDCPPT-TCARPQSGPGQ
480 490 500 510 520 530
310 320 330 340 350
pF1KB8 CCPFTQAVCCEDHIHCCPAGFT--------CDTQKGTCEQGPHQVPWMEKAPAHLSLPD-
::: :... .:. : :.: . :. : .:: ::
NP_955 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCP---RAPCAHPLPGT
540 550 560 570 580 590
360 370 380 390
pF1KB8 --PQALK------RDVPCDNVSSCPSSDTC--CQLTSGEWGC----C---PIPEAVCCSD
:. . .. : :: : : :. ::. : : : :: :
NP_955 CCPNDCSGCAFGGKEYPSGADFPHPS-DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPG
600 610 620 630 640 650
400 410 420 430 440 450
pF1KB8 HQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTC--C
.:::: . : . : : :. .: : :. : :. : :
NP_955 --ECCPQCPAAPAPAGCPR-----------PG----AAHAR----HQEYFSPPGDPCRRC
660 670 680
460 470 480 490 500 510
pF1KB8 PSLGGSWACCQLP--HAVCCEDRQH-CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHV
: :: .: .:: : : . :: :::. : .. :: .:.. : :: .
NP_955 LCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQG----KEFASGE--RF--PSPTA
690 700 710 720 730 740
520 530 540 550 560
pF1KB8 GVKDVECGEGHFCHDNQTCCRDNRQGWACCPY-RQGVCCAD---RRH---CCPAGFRCAA
. . : :: . ..: : ::. .: :: : . : : .:.: .
NP_955 ACHLCLCWEGSVSCEPKACAP------ALCPFPARGDCCPDCDGEGHGIGSCRGGMR-ET
750 760 770 780 790
570 580 590
pF1KB8 RGTKCLRREAPRWDAPLRDPALRQLL
:: :: :
NP_955 RGLGQNNLYCPRVDLKYLLQ
800 810
>>XP_016867681 (OMIM: 609344) PREDICTED: kielin/chordin- (1347 aa)
initn: 135 init1: 70 opt: 322 Z-score: 249.1 bits: 57.3 E(85289): 3.9e-07
Smith-Waterman score: 359; 25.7% identity (41.2% similar) in 556 aa overlap (55-558:6-494)
30 40 50 60 70 80
pF1KB8 FCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCC
.::: : . ::: . :.....
XP_016 MAKSGQHLGTPAE-----SAG---AWRVTSSAASE
10 20
90 100 110 120 130 140
pF1KB8 PFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDF--STCCVM
: : : : .. : . .:. . . :: . : . :: .
XP_016 NVPACVHTQPGPSQAPAAL--------CVM-NGSVQCEPLPCPPVPCRHPGKIPGQCCPV
30 40 50 60 70
150 160 170 180 190
pF1KB8 VDGS--WGCCPMPQASC-CEDR---VHC-CPHGAF-CDLVHTRC-ITPTGTHPLAKKL-P
:: : . : . ..: :.: : : :. . .: .:: . ...: :
XP_016 CDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE--EQECPVTPCALPASGRQLCP
80 90 100 110 120 130
200 210 220 230 240
pF1KB8 AQRTNRAVALSSSVMCPDARS----RCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCP
: . . . ::.: : :: : : : : : . :::
XP_016 ACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKC----GAVLCPPAPCQHPTQPPGACCP
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB8 QDTVCDLIQSKCLSKENATTDLLTKLPAHTV----GDVKCDMEVSCPDGYTCCRLQSGAW
. : .:. .. . :: . : :. : : :.. :.:: :: : :::
XP_016 SCDSCTY-HSQVYANGQNFTDADS--PCHACHCQDGTVTCSL-VDCPPT-TCARPQSGPG
200 210 220 230 240
310 320 330 340 350
pF1KB8 GCCPFTQAVCCEDHIHCCPAGFT--------CDTQKGTCEQGPHQVPWMEKAPAHLSLPD
::: :... .:. : :.: . :. : .:: ::
XP_016 QCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCP---RAPCAHPLPG
250 260 270 280 290 300
360 370 380 390
pF1KB8 ---PQALK------RDVPCDNVSSCPSSDTC--CQLTSGEWGC----C---PIPEAVCCS
:. . .. : :: : : :. ::. : : : :: :
XP_016 TCCPNDCSGCAFGGKEYPSGADFPHPS-DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLP
310 320 330 340 350 360
400 410 420 430 440 450
pF1KB8 DHQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTC--
. :::: . : . : : :. .: : :. : :. :
XP_016 GE--CCPQCPAAPAPAGCPR-----------PGA----AHARH----QEYFSPPGDPCRR
370 380 390 400
460 470 480 490 500 510
pF1KB8 CPSLGGSWACCQLP--HAVCCEDRQH-CCPAGYTCNVKARSCEKEVVSAQPATFLARSPH
: : :: .: .:: : : . :: :::. : .. :: .:.. : ::
XP_016 CLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQG----KEFASGE--RF--PSPT
410 420 430 440 450
520 530 540 550 560 570
pF1KB8 VGVKDVECGEGHFCHDNQTCCRDNRQGWACCPY-RQGVCCADRRHCCPAGFRCAARGTKC
.. . : :: . ..: : ::. .: :: : :
XP_016 AACHLCLCWEGSVSCEPKACAP------ALCPFPARGDCCPDCDGCEYLGESYLSNQEFP
460 470 480 490 500
580 590
pF1KB8 LRREAPRWDAPLRDPALRQLL
XP_016 DPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPD
510 520 530 540 550 560
>>XP_016867680 (OMIM: 609344) PREDICTED: kielin/chordin- (1347 aa)
initn: 135 init1: 70 opt: 322 Z-score: 249.1 bits: 57.3 E(85289): 3.9e-07
Smith-Waterman score: 359; 25.7% identity (41.2% similar) in 556 aa overlap (55-558:6-494)
30 40 50 60 70 80
pF1KB8 FCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCC
.::: : . ::: . :.....
XP_016 MAKSGQHLGTPAE-----SAG---AWRVTSSAASE
10 20
90 100 110 120 130 140
pF1KB8 PFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDF--STCCVM
: : : : .. : . .:. . . :: . : . :: .
XP_016 NVPACVHTQPGPSQAPAAL--------CVM-NGSVQCEPLPCPPVPCRHPGKIPGQCCPV
30 40 50 60 70
150 160 170 180 190
pF1KB8 VDGS--WGCCPMPQASC-CEDR---VHC-CPHGAF-CDLVHTRC-ITPTGTHPLAKKL-P
:: : . : . ..: :.: : : :. . .: .:: . ...: :
XP_016 CDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE--EQECPVTPCALPASGRQLCP
80 90 100 110 120 130
200 210 220 230 240
pF1KB8 AQRTNRAVALSSSVMCPDARS----RCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCP
: . . . ::.: : :: : : : : : . :::
XP_016 ACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKC----GAVLCPPAPCQHPTQPPGACCP
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB8 QDTVCDLIQSKCLSKENATTDLLTKLPAHTV----GDVKCDMEVSCPDGYTCCRLQSGAW
. : .:. .. . :: . : :. : : :.. :.:: :: : :::
XP_016 SCDSCTY-HSQVYANGQNFTDADS--PCHACHCQDGTVTCSL-VDCPPT-TCARPQSGPG
200 210 220 230 240
310 320 330 340 350
pF1KB8 GCCPFTQAVCCEDHIHCCPAGFT--------CDTQKGTCEQGPHQVPWMEKAPAHLSLPD
::: :... .:. : :.: . :. : .:: ::
XP_016 QCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCP---RAPCAHPLPG
250 260 270 280 290 300
360 370 380 390
pF1KB8 ---PQALK------RDVPCDNVSSCPSSDTC--CQLTSGEWGC----C---PIPEAVCCS
:. . .. : :: : : :. ::. : : : :: :
XP_016 TCCPNDCSGCAFGGKEYPSGADFPHPS-DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLP
310 320 330 340 350 360
400 410 420 430 440 450
pF1KB8 DHQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTC--
. :::: . : . : : :. .: : :. : :. :
XP_016 GE--CCPQCPAAPAPAGCPR-----------PGA----AHARH----QEYFSPPGDPCRR
370 380 390 400
460 470 480 490 500 510
pF1KB8 CPSLGGSWACCQLP--HAVCCEDRQH-CCPAGYTCNVKARSCEKEVVSAQPATFLARSPH
: : :: .: .:: : : . :: :::. : .. :: .:.. : ::
XP_016 CLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQG----KEFASGE--RF--PSPT
410 420 430 440 450
520 530 540 550 560 570
pF1KB8 VGVKDVECGEGHFCHDNQTCCRDNRQGWACCPY-RQGVCCADRRHCCPAGFRCAARGTKC
.. . : :: . ..: : ::. .: :: : :
XP_016 AACHLCLCWEGSVSCEPKACAP------ALCPFPARGDCCPDCDGCEYLGESYLSNQEFP
460 470 480 490 500
580 590
pF1KB8 LRREAPRWDAPLRDPALRQLL
XP_016 DPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPD
510 520 530 540 550 560
>>XP_016867683 (OMIM: 609344) PREDICTED: kielin/chordin- (1093 aa)
initn: 167 init1: 70 opt: 318 Z-score: 247.1 bits: 56.6 E(85289): 5e-07
Smith-Waterman score: 440; 26.3% identity (40.7% similar) in 615 aa overlap (19-558:228-780)
10 20 30 40
pF1KB8 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSC--CRPLL
.:: . :: : :: .: :
XP_016 LYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSP-CPEPV-LRPGHCCPTCQGCTEGG
200 210 220 230 240 250
50 60 70 80 90 100
pF1KB8 DKWPTTLSRHL-GGPCQVDAHCSAGH-SCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFH
..: : ::.. .: :: .: .: ::.: : :::
XP_016 SHWEHGQEWTTPGDPCRI-CRCLEGHIQC--RQRECASLCPYPARPLPGT---CCPVCDG
260 270 280 290 300
110 120 130 140
pF1KB8 CSADGRSCFQRSGNN------------SVGAIQCPDSQFECPDF---------STCCVMV
: .:: .:::. . :..:: . :: . :: .
XP_016 CFLNGRE--HRSGEPVGSGDPCSHCRCANGSVQCE--PLPCPPVPCRHPGKIPGQCCPVC
310 320 330 340 350 360
150 160 170 180 190
pF1KB8 DGS--WGCCPMPQASC-CEDR---VHC-CPHGAF-CDLVHTRC-ITPTGTHPLAKKL-PA
:: : . : . ..: :.: : : :. . .: .:: . ...: ::
XP_016 DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE--EQECPVTPCALPASGRQLCPA
370 380 390 400 410 420
200 210 220 230 240
pF1KB8 QRTNRAVALSSSVMCPDARS----RCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQ
. . . ::.: : :: : : : : : . :::.
XP_016 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKC----GAVLCPPAPCQHPTQPPGACCPS
430 440 450 460 470
250 260 270 280 290 300
pF1KB8 DTVCDLIQSKCLSKENATTDLLTKLPAHTV----GDVKCDMEVSCPDGYTCCRLQSGAWG
: .:. .. . :: . : :. : : :.. :.:: :: : :::
XP_016 CDSCTY-HSQVYANGQNFTD--ADSPCHACHCQDGTVTCSL-VDCPPT-TCARPQSGPGQ
480 490 500 510 520 530
310 320 330 340 350
pF1KB8 CCPFTQAVCCEDHIHCCPAGFT--------CDTQKGTCEQGPHQVPWMEKAPAHLSLPD-
::: :... .:. : :.: . :. : .:: ::
XP_016 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCP---RAPCAHPLPGT
540 550 560 570 580 590
360 370 380 390
pF1KB8 --PQALK------RDVPCDNVSSCPSSDTC--CQLTSGEWGC----C---PIPEAVCCSD
:. . .. : :: : : :. ::. : : : :: :
XP_016 CCPNDCSGCAFGGKEYPSGADFPHPS-DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPG
600 610 620 630 640 650
400 410 420 430 440 450
pF1KB8 HQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTC--C
. :::: . : . : : :. .: : :. : :. : :
XP_016 E--CCPQCPAAPAPAGCPR-----------PGA----AHAR----HQEYFSPPGDPCRRC
660 670 680
460 470 480 490 500 510
pF1KB8 PSLGGSWACCQLP--HAVCCEDRQH-CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHV
: :: .: .:: : : . :: :::. : .. :: .:.. : :: .
XP_016 LCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQG----KEFASGE--RF--PSPTA
690 700 710 720 730 740
520 530 540 550 560 570
pF1KB8 GVKDVECGEGHFCHDNQTCCRDNRQGWACCPY-RQGVCCADRRHCCPAGFRCAARGTKCL
. . : :: . ..: : ::. .: :: : :
XP_016 ACHLCLCWEGSVSCEPKACAP------ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPD
750 760 770 780 790
580 590
pF1KB8 RREAPRWDAPLRDPALRQLL
XP_016 PREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQALLLDSPLCQDAATMASL
800 810 820 830 840 850
>>XP_016867682 (OMIM: 609344) PREDICTED: kielin/chordin- (1102 aa)
initn: 167 init1: 70 opt: 318 Z-score: 247.1 bits: 56.6 E(85289): 5e-07
Smith-Waterman score: 440; 26.3% identity (40.7% similar) in 615 aa overlap (19-558:228-780)
10 20 30 40
pF1KB8 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSC--CRPLL
.:: . :: : :: .: :
XP_016 LYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSP-CPEPV-LRPGHCCPTCQGCTEGG
200 210 220 230 240 250
50 60 70 80 90 100
pF1KB8 DKWPTTLSRHL-GGPCQVDAHCSAGH-SCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFH
..: : ::.. .: :: .: .: ::.: : :::
XP_016 SHWEHGQEWTTPGDPCRI-CRCLEGHIQC--RQRECASLCPYPARPLPGT---CCPVCDG
260 270 280 290 300
110 120 130 140
pF1KB8 CSADGRSCFQRSGNN------------SVGAIQCPDSQFECPDF---------STCCVMV
: .:: .:::. . :..:: . :: . :: .
XP_016 CFLNGRE--HRSGEPVGSGDPCSHCRCANGSVQCE--PLPCPPVPCRHPGKIPGQCCPVC
310 320 330 340 350 360
150 160 170 180 190
pF1KB8 DGS--WGCCPMPQASC-CEDR---VHC-CPHGAF-CDLVHTRC-ITPTGTHPLAKKL-PA
:: : . : . ..: :.: : : :. . .: .:: . ...: ::
XP_016 DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE--EQECPVTPCALPASGRQLCPA
370 380 390 400 410 420
200 210 220 230 240
pF1KB8 QRTNRAVALSSSVMCPDARS----RCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQ
. . . ::.: : :: : : : : : . :::.
XP_016 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKC----GAVLCPPAPCQHPTQPPGACCPS
430 440 450 460 470
250 260 270 280 290 300
pF1KB8 DTVCDLIQSKCLSKENATTDLLTKLPAHTV----GDVKCDMEVSCPDGYTCCRLQSGAWG
: .:. .. . :: . : :. : : :.. :.:: :: : :::
XP_016 CDSCTY-HSQVYANGQNFTD--ADSPCHACHCQDGTVTCSL-VDCPPT-TCARPQSGPGQ
480 490 500 510 520 530
310 320 330 340 350
pF1KB8 CCPFTQAVCCEDHIHCCPAGFT--------CDTQKGTCEQGPHQVPWMEKAPAHLSLPD-
::: :... .:. : :.: . :. : .:: ::
XP_016 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCP---RAPCAHPLPGT
540 550 560 570 580 590
360 370 380 390
pF1KB8 --PQALK------RDVPCDNVSSCPSSDTC--CQLTSGEWGC----C---PIPEAVCCSD
:. . .. : :: : : :. ::. : : : :: :
XP_016 CCPNDCSGCAFGGKEYPSGADFPHPS-DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPG
600 610 620 630 640 650
400 410 420 430 440 450
pF1KB8 HQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTC--C
. :::: . : . : : :. .: : :. : :. : :
XP_016 E--CCPQCPAAPAPAGCPR-----------PGA----AHAR----HQEYFSPPGDPCRRC
660 670 680
460 470 480 490 500 510
pF1KB8 PSLGGSWACCQLP--HAVCCEDRQH-CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHV
: :: .: .:: : : . :: :::. : .. :: .:.. : :: .
XP_016 LCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQG----KEFASGE--RF--PSPTA
690 700 710 720 730 740
520 530 540 550 560 570
pF1KB8 GVKDVECGEGHFCHDNQTCCRDNRQGWACCPY-RQGVCCADRRHCCPAGFRCAARGTKCL
. . : :: . ..: : ::. .: :: : :
XP_016 ACHLCLCWEGSVSCEPKACAP------ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPD
750 760 770 780 790
580 590
pF1KB8 RREAPRWDAPLRDPALRQLL
XP_016 PREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQALLLDSPLCQDAATMASL
800 810 820 830 840 850
>>XP_016867679 (OMIM: 609344) PREDICTED: kielin/chordin- (1466 aa)
initn: 135 init1: 70 opt: 318 Z-score: 245.8 bits: 56.8 E(85289): 6e-07
Smith-Waterman score: 440; 26.3% identity (40.7% similar) in 615 aa overlap (19-558:228-780)
10 20 30 40
pF1KB8 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSC--CRPLL
.:: . :: : :: .: :
XP_016 LYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCPPSP-CPEPV-LRPGHCCPTCQGCTEGG
200 210 220 230 240 250
50 60 70 80 90 100
pF1KB8 DKWPTTLSRHL-GGPCQVDAHCSAGH-SCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFH
..: : ::.. .: :: .: .: ::.: : :::
XP_016 SHWEHGQEWTTPGDPCRI-CRCLEGHIQC--RQRECASLCPYPARPLPGT---CCPVCDG
260 270 280 290 300
110 120 130 140
pF1KB8 CSADGRSCFQRSGNN------------SVGAIQCPDSQFECPDF---------STCCVMV
: .:: .:::. . :..:: . :: . :: .
XP_016 CFLNGRE--HRSGEPVGSGDPCSHCRCANGSVQCE--PLPCPPVPCRHPGKIPGQCCPVC
310 320 330 340 350 360
150 160 170 180 190
pF1KB8 DGS--WGCCPMPQASC-CEDR---VHC-CPHGAF-CDLVHTRC-ITPTGTHPLAKKL-PA
:: : . : . ..: :.: : : :. . .: .:: . ...: ::
XP_016 DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCE--EQECPVTPCALPASGRQLCPA
370 380 390 400 410 420
200 210 220 230 240
pF1KB8 QRTNRAVALSSSVMCPDARS----RCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQ
. . . ::.: : :: : : : : : . :::.
XP_016 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKC----GAVLCPPAPCQHPTQPPGACCPS
430 440 450 460 470
250 260 270 280 290 300
pF1KB8 DTVCDLIQSKCLSKENATTDLLTKLPAHTV----GDVKCDMEVSCPDGYTCCRLQSGAWG
: .:. .. . :: . : :. : : :.. :.:: :: : :::
XP_016 CDSCTY-HSQVYANGQNFTD--ADSPCHACHCQDGTVTCSL-VDCPPT-TCARPQSGPGQ
480 490 500 510 520 530
310 320 330 340 350
pF1KB8 CCPFTQAVCCEDHIHCCPAGFT--------CDTQKGTCEQGPHQVPWMEKAPAHLSLPD-
::: :... .:. : :.: . :. : .:: ::
XP_016 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCP---RAPCAHPLPGT
540 550 560 570 580 590
360 370 380 390
pF1KB8 --PQALK------RDVPCDNVSSCPSSDTC--CQLTSGEWGC----C---PIPEAVCCSD
:. . .. : :: : : :. ::. : : : :: :
XP_016 CCPNDCSGCAFGGKEYPSGADFPHPS-DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPG
600 610 620 630 640 650
400 410 420 430 440 450
pF1KB8 HQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTC--C
. :::: . : . : : :. .: : :. : :. : :
XP_016 E--CCPQCPAAPAPAGCPR-----------PGA----AHAR----HQEYFSPPGDPCRRC
660 670 680
460 470 480 490 500 510
pF1KB8 PSLGGSWACCQLP--HAVCCEDRQH-CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHV
: :: .: .:: : : . :: :::. : .. :: .:.. : :: .
XP_016 LCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQG----KEFASGE--RF--PSPTA
690 700 710 720 730 740
520 530 540 550 560 570
pF1KB8 GVKDVECGEGHFCHDNQTCCRDNRQGWACCPY-RQGVCCADRRHCCPAGFRCAARGTKCL
. . : :: . ..: : ::. .: :: : :
XP_016 ACHLCLCWEGSVSCEPKACAP------ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPD
750 760 770 780 790
580 590
pF1KB8 RREAPRWDAPLRDPALRQLL
XP_016 PREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDP
800 810 820 830 840 850
593 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:54:16 2016 done: Fri Nov 4 09:54:17 2016
Total Scan time: 8.970 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]