Result of FASTA (omim) for
pF1KB8140
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8140, 271 aa
1>>>pF1KB8140 271 - 271 aa - 271 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9426+/-0.000361; mu= 17.1598+/- 0.022
mean_var=71.3211+/-14.591, 0's: 0 Z-trim(114.9): 75 B-trim: 679 in 1/49
Lambda= 0.151868
statistics sampled from 24862 (24943) to 24862 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.292), width: 16
Scan time: 6.390
The best scores are: opt bits E(85289)
NP_067026 (OMIM: 616883) signal recognition partic ( 271) 1710 383.6 2.1e-106
NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 172 46.5 4.4e-05
NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 163 44.5 0.00017
NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 156 43.0 0.00048
NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 150 41.7 0.0012
NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 150 41.7 0.0012
XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 150 41.7 0.0012
NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 144 40.3 0.003
NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 144 40.3 0.003
NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 144 40.3 0.003
NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 144 40.3 0.003
NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 141 39.7 0.0047
NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 141 39.7 0.0049
NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 141 39.7 0.0051
XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 141 39.7 0.0051
NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 141 39.7 0.0051
>>NP_067026 (OMIM: 616883) signal recognition particle r (271 aa)
initn: 1710 init1: 1710 opt: 1710 Z-score: 2031.3 bits: 383.6 E(85289): 2.1e-106
Smith-Waterman score: 1710; 100.0% identity (100.0% similar) in 271 aa overlap (1-271:1-271)
10 20 30 40 50 60
pF1KB8 MASADSRRVADGGGAGGTFQPYLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MASADSRRVADGGGAGGTFQPYLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RSSQRAVLLVGLCDSGKTLLFVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 RSSQRAVLLVGLCDSGKTLLFVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 HESLRLQFLERFKSSARAIVFVVDSAAFQREVKDVAEFLYQVLIDSMGLKNTPSFLIACN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 HESLRLQFLERFKSSARAIVFVVDSAAFQREVKDVAEFLYQVLIDSMGLKNTPSFLIACN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KQDIAMAKSAKLIQQQLEKELNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 KQDIAMAKSAKLIQQQLEKELNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLK
190 200 210 220 230 240
250 260 270
pF1KB8 VEFLECSAKGGRGDVGSADIQDLEKWLAKIA
:::::::::::::::::::::::::::::::
NP_067 VEFLECSAKGGRGDVGSADIQDLEKWLAKIA
250 260 270
>>NP_079323 (OMIM: 614439) ADP-ribosylation factor-like (192 aa)
initn: 107 init1: 54 opt: 172 Z-score: 212.2 bits: 46.5 E(85289): 4.4e-05
Smith-Waterman score: 172; 30.9% identity (63.8% similar) in 149 aa overlap (58-205:7-149)
30 40 50 60 70 80
pF1KB8 QELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGKTLLFVRLLTG
.. ...: :::.:: ..::. :. .:
NP_079 MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKL--K
10 20 30
90 100 110 120 130 140
pF1KB8 LYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSARAIVFVVDSAA
: .: : : . : .. .:. :::. :. :.:..: . . .. ..:.::::.
NP_079 LAKDITTIPTIGFNVEMIELERNLSLTVWDVGGQEKMRTVW-GCYCENTDGLVYVVDSTD
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB8 FQREVKDVAEFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLE-KELNTLRV
:: .. .: . .. . .::.: :.: ::::. : .:. : .... :.: . :
NP_079 KQRLEESQRQFEH--ILKNEHIKNVPVVLLA-NKQDMPGALTAEDITRMFKVKKLCSDRN
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB8 TRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADIQDLEKW
NP_079 WYVQPCCALTGEGLAQGFRKLTGFVKSHMKSRGDTLAFFKQN
160 170 180 190
>>NP_001658 (OMIM: 601175) ADP-ribosylation factor-like (184 aa)
initn: 146 init1: 57 opt: 163 Z-score: 201.8 bits: 44.5 E(85289): 0.00017
Smith-Waterman score: 164; 31.6% identity (67.1% similar) in 158 aa overlap (48-205:3-148)
20 30 40 50 60 70
pF1KB8 TFQPYLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGK
:::.. : ..... : .:..:: ..::
NP_001 MGLLTIL--KKMKQKERELR-LLMLGLDNAGK
10 20
80 90 100 110 120 130
pF1KB8 TLLFVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSAR
: .. .. .: :: : : . . .. ..:: .:.. :. :..::: . . :.:.
NP_001 TTILKKF-NGEDIDT-ISPTLGFNI-KTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTD-
30 40 50 60 70 80
140 150 160 170 180 190
pF1KB8 AIVFVVDSAAFQREVKDVAEFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQL
....::::: :: ..: . : ..:.. : .. ..:: ::::. : :.. :.. :
NP_001 GLIWVVDSADRQR-MQDCQRELQSLLVEER-LAGA-TLLIFANKQDLPGALSSNAIREVL
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB8 EKELNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGS
: :...:
NP_001 E--LDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRIFTAD
150 160 170 180
>>NP_036229 (OMIM: 608960) ADP-ribosylation factor-like (179 aa)
initn: 95 init1: 53 opt: 156 Z-score: 193.6 bits: 43.0 E(85289): 0.00048
Smith-Waterman score: 156; 26.6% identity (63.0% similar) in 154 aa overlap (45-198:1-143)
20 30 40 50 60 70
pF1KB8 AGGTFQPYLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCD
...:.: . :.:. . .. :..::: .
NP_036 MGILFTRI-WRLFNHQ---EHKVIIVGLDN
10 20
80 90 100 110 120 130
pF1KB8 SGKTLLFVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKS
.::: .. .. . :. .: .. .::.: . . :. :.:::: .. . . .
NP_036 AGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNTR---FLMWDIGGQESLRSSW-NTYYT
30 40 50 60 70 80
140 150 160 170 180 190
pF1KB8 SARAIVFVVDSAAFQREVKDVAEFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQ
... .. ::::. .: .. . : ::..: :... ..:: ::::. .. :.
NP_036 NTEFVIVVVDSTDRER-ISVTREELYKMLAHE-DLRKA-GLLIFANKQDVKECMTVAEIS
90 100 110 120 130
200 210 220 230 240 250
pF1KB8 QQLEKELNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGD
: :.
NP_036 QFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
140 150 160 170
>>NP_848930 (OMIM: 608909) ADP-ribosylation factor-like (179 aa)
initn: 129 init1: 55 opt: 150 Z-score: 186.5 bits: 41.7 E(85289): 0.0012
Smith-Waterman score: 150; 28.9% identity (61.1% similar) in 149 aa overlap (49-197:1-142)
20 30 40 50 60 70
pF1KB8 FQPYLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGKT
. :.: :: .... :..::: ..:::
NP_848 MGLIFAKLWSLFCNQEHKVIIVGLDNAGKT
10 20 30
80 90 100 110 120 130
pF1KB8 LLFVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSARA
.. ..: . :. .: .. :.:.. . . :. :.:::: .. . . :...
NP_848 TILYQFLMNEVVHTSPTIGSNVEEIVVKNTH---FLMWDIGGQESLRSSW-NTYYSNTEF
40 50 60 70 80
140 150 160 170 180 190
pF1KB8 IVFVVDSAAFQREVKDVAEFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLE
:..:::: .: . . : ::..: :... . :: ::::. .: :.. :
NP_848 IILVVDSIDRER-LAITKEELYRMLAHE-DLRKA-AVLIFANKQDMKGCMTAAEISKYLT
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB8 KELNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSA
NP_848 LSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR
150 160 170
>>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa)
initn: 99 init1: 45 opt: 150 Z-score: 186.5 bits: 41.7 E(85289): 0.0012
Smith-Waterman score: 153; 28.4% identity (63.9% similar) in 155 aa overlap (52-205:4-149)
30 40 50 60 70 80
pF1KB8 YLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRA-VLLVGLCDSGKTLL
.: .:..: .... .:.::: .::: .
NP_001 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTI
10 20 30
90 100 110 120 130 140
pF1KB8 FVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSARAIV
. .: : : .: . . . .: :.:. :. :....: . . :... ....
NP_001 LYKLKLGEIVTTIPTIGFNVETVEYKNI---SFTVWDVGGQDKIRPLWRHYFQNT-QGLI
40 50 60 70 80
150 160 170 180 190 200
pF1KB8 FVVDSAAFQREVKDVAEFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLEKE
::::: .: :... : :...: .. :... .:. ::::. : .: : ..:
NP_001 FVVDSNDRER-VNEAREELMRMLAEDE-LRDA-VLLVFANKQDLPNAMNAAEITDKLG--
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB8 LNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADI
:..::
NP_001 LHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK
150 160 170 180
>>XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosylatio (181 aa)
initn: 99 init1: 45 opt: 150 Z-score: 186.5 bits: 41.7 E(85289): 0.0012
Smith-Waterman score: 153; 28.4% identity (63.9% similar) in 155 aa overlap (52-205:4-149)
30 40 50 60 70 80
pF1KB8 YLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRA-VLLVGLCDSGKTLL
.: .:..: .... .:.::: .::: .
XP_005 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTI
10 20 30
90 100 110 120 130 140
pF1KB8 FVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSARAIV
. .: : : .: . . . .: :.:. :. :....: . . :... ....
XP_005 LYKLKLGEIVTTIPTIGFNVETVEYKNI---SFTVWDVGGQDKIRPLWRHYFQNT-QGLI
40 50 60 70 80
150 160 170 180 190 200
pF1KB8 FVVDSAAFQREVKDVAEFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLEKE
::::: .: :... : :...: .. :... .:. ::::. : .: : ..:
XP_005 FVVDSNDRER-VNEAREELMRMLAEDE-LRDA-VLLVFANKQDLPNAMNAAEITDKLG--
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB8 LNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADI
:..::
XP_005 LHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK
150 160 170 180
>>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa)
initn: 99 init1: 45 opt: 144 Z-score: 179.4 bits: 40.3 E(85289): 0.003
Smith-Waterman score: 147; 29.5% identity (63.3% similar) in 139 aa overlap (67-205:20-149)
40 50 60 70 80 90
pF1KB8 LLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGKTLLFVRLLTGLYRDTQTSI
.:.::: .::: .. .: : : .:
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTI
10 20 30 40
100 110 120 130 140 150
pF1KB8 TDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSARAIVFVVDSAAFQREVKDVA
. . . .: :.:. :. :....: . . :... ....::::: .: :...
NP_001 GFNVETVEYKNI---SFTVWDVGGQDKIRPLWRHYFQNT-QGLIFVVDSNDRER-VNEAR
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB8 EFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRSAAPSTLD
: :...: .. :... .:. ::::. : .: : ..: :..::
NP_001 EELMRMLAEDE-LRDA-VLLVFANKQDLPNAMNAAEITDKLG--LHSLRHRNWYIQATCA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB8 SSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADIQDLEKWLAKIA
NP_001 TSGDGLYEGLDWLSNQLRNQK
170 180
>>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa)
initn: 99 init1: 45 opt: 144 Z-score: 179.4 bits: 40.3 E(85289): 0.003
Smith-Waterman score: 147; 29.5% identity (63.3% similar) in 139 aa overlap (67-205:20-149)
40 50 60 70 80 90
pF1KB8 LLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGKTLLFVRLLTGLYRDTQTSI
.:.::: .::: .. .: : : .:
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTI
10 20 30 40
100 110 120 130 140 150
pF1KB8 TDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSARAIVFVVDSAAFQREVKDVA
. . . .: :.:. :. :....: . . :... ....::::: .: :...
NP_001 GFNVETVEYKNI---SFTVWDVGGQDKIRPLWRHYFQNT-QGLIFVVDSNDRER-VNEAR
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB8 EFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRSAAPSTLD
: :...: .. :... .:. ::::. : .: : ..: :..::
NP_001 EELMRMLAEDE-LRDA-VLLVFANKQDLPNAMNAAEITDKLG--LHSLRHRNWYIQATCA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB8 SSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADIQDLEKWLAKIA
NP_001 TSGDGLYEGLDWLSNQLRNQK
170 180
>>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa)
initn: 99 init1: 45 opt: 144 Z-score: 179.4 bits: 40.3 E(85289): 0.003
Smith-Waterman score: 147; 29.5% identity (63.3% similar) in 139 aa overlap (67-205:20-149)
40 50 60 70 80 90
pF1KB8 LLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGKTLLFVRLLTGLYRDTQTSI
.:.::: .::: .. .: : : .:
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTI
10 20 30 40
100 110 120 130 140 150
pF1KB8 TDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSARAIVFVVDSAAFQREVKDVA
. . . .: :.:. :. :....: . . :... ....::::: .: :...
NP_001 GFNVETVEYKNI---SFTVWDVGGQDKIRPLWRHYFQNT-QGLIFVVDSNDRER-VNEAR
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB8 EFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRSAAPSTLD
: :...: .. :... .:. ::::. : .: : ..: :..::
NP_001 EELMRMLAEDE-LRDA-VLLVFANKQDLPNAMNAAEITDKLG--LHSLRHRNWYIQATCA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB8 SSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADIQDLEKWLAKIA
NP_001 TSGDGLYEGLDWLSNQLRNQK
170 180
271 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:56:22 2016 done: Fri Nov 4 09:56:23 2016
Total Scan time: 6.390 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]