FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8141, 136 aa 1>>>pF1KB8141 136 - 136 aa - 136 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2254+/-0.000318; mu= 12.3770+/- 0.020 mean_var=66.4790+/-13.238, 0's: 0 Z-trim(115.7): 22 B-trim: 352 in 1/53 Lambda= 0.157301 statistics sampled from 26327 (26349) to 26327 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.309), width: 16 Scan time: 4.400 The best scores are: opt bits E(85289) NP_002098 (OMIM: 601128) histone H3.3 [Homo sapien ( 136) 863 203.9 6.5e-53 NP_005315 (OMIM: 601058) histone H3.3 [Homo sapien ( 136) 863 203.9 6.5e-53 NP_066403 (OMIM: 142780) histone H3.2 [Homo sapien ( 136) 843 199.4 1.5e-51 NP_003528 (OMIM: 602819) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003525 (OMIM: 602815) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003526 (OMIM: 602817) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003521 (OMIM: 602811) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003520 (OMIM: 602810) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_066298 (OMIM: 602816) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003527 (OMIM: 602818) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003524 (OMIM: 602814) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003523 (OMIM: 602813) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003522 (OMIM: 602812) histone H3.1 [Homo sapien ( 136) 837 198.0 3.9e-51 NP_003484 (OMIM: 602820) histone H3.1t [Homo sapie ( 136) 819 193.9 6.6e-50 NP_001013721 (OMIM: 616134) histone H3.3C [Homo sa ( 135) 815 193.0 1.2e-49 NP_001800 (OMIM: 117139) histone H3-like centromer ( 140) 373 92.7 2e-19 NP_001035891 (OMIM: 117139) histone H3-like centro ( 114) 170 46.6 1.2e-05 >>NP_002098 (OMIM: 601128) histone H3.3 [Homo sapiens] (136 aa) initn: 863 init1: 863 opt: 863 Z-score: 1070.9 bits: 203.9 E(85289): 6.5e-53 Smith-Waterman score: 863; 100.0% identity (100.0% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_002 MPKDIQLARRIRGERA 130 >>NP_005315 (OMIM: 601058) histone H3.3 [Homo sapiens] (136 aa) initn: 863 init1: 863 opt: 863 Z-score: 1070.9 bits: 203.9 E(85289): 6.5e-53 Smith-Waterman score: 863; 100.0% identity (100.0% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_005 MPKDIQLARRIRGERA 130 >>NP_066403 (OMIM: 142780) histone H3.2 [Homo sapiens] (136 aa) initn: 843 init1: 843 opt: 843 Z-score: 1046.4 bits: 199.4 E(85289): 1.5e-51 Smith-Waterman score: 843; 97.1% identity (99.3% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_066 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::.:. ::::::::::::::::::::::::::::: NP_066 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_066 MPKDIQLARRIRGERA 130 >>NP_003528 (OMIM: 602819) histone H3.1 [Homo sapiens] (136 aa) initn: 837 init1: 837 opt: 837 Z-score: 1039.1 bits: 198.0 E(85289): 3.9e-51 Smith-Waterman score: 837; 96.3% identity (98.5% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_003 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::.:. ::::: ::::::::::::::::::::::: NP_003 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_003 MPKDIQLARRIRGERA 130 >>NP_003525 (OMIM: 602815) histone H3.1 [Homo sapiens] (136 aa) initn: 837 init1: 837 opt: 837 Z-score: 1039.1 bits: 198.0 E(85289): 3.9e-51 Smith-Waterman score: 837; 96.3% identity (98.5% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_003 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::.:. ::::: ::::::::::::::::::::::: NP_003 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_003 MPKDIQLARRIRGERA 130 >>NP_003526 (OMIM: 602817) histone H3.1 [Homo sapiens] (136 aa) initn: 837 init1: 837 opt: 837 Z-score: 1039.1 bits: 198.0 E(85289): 3.9e-51 Smith-Waterman score: 837; 96.3% identity (98.5% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_003 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::.:. ::::: ::::::::::::::::::::::: NP_003 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_003 MPKDIQLARRIRGERA 130 >>NP_003521 (OMIM: 602811) histone H3.1 [Homo sapiens] (136 aa) initn: 837 init1: 837 opt: 837 Z-score: 1039.1 bits: 198.0 E(85289): 3.9e-51 Smith-Waterman score: 837; 96.3% identity (98.5% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_003 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::.:. ::::: ::::::::::::::::::::::: NP_003 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_003 MPKDIQLARRIRGERA 130 >>NP_003520 (OMIM: 602810) histone H3.1 [Homo sapiens] (136 aa) initn: 837 init1: 837 opt: 837 Z-score: 1039.1 bits: 198.0 E(85289): 3.9e-51 Smith-Waterman score: 837; 96.3% identity (98.5% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_003 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::.:. ::::: ::::::::::::::::::::::: NP_003 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_003 MPKDIQLARRIRGERA 130 >>NP_066298 (OMIM: 602816) histone H3.1 [Homo sapiens] (136 aa) initn: 837 init1: 837 opt: 837 Z-score: 1039.1 bits: 198.0 E(85289): 3.9e-51 Smith-Waterman score: 837; 96.3% identity (98.5% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_066 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::.:. ::::: ::::::::::::::::::::::: NP_066 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_066 MPKDIQLARRIRGERA 130 >>NP_003527 (OMIM: 602818) histone H3.1 [Homo sapiens] (136 aa) initn: 837 init1: 837 opt: 837 Z-score: 1039.1 bits: 198.0 E(85289): 3.9e-51 Smith-Waterman score: 837; 96.3% identity (98.5% similar) in 136 aa overlap (1-136:1-136) 10 20 30 40 50 60 pF1KB8 MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_003 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI :::::::::::::::::::::::::::.:. ::::: ::::::::::::::::::::::: NP_003 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI 70 80 90 100 110 120 130 pF1KB8 MPKDIQLARRIRGERA :::::::::::::::: NP_003 MPKDIQLARRIRGERA 130 136 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:57:03 2016 done: Fri Nov 4 09:57:04 2016 Total Scan time: 4.400 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]