FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8147, 268 aa 1>>>pF1KB8147 268 - 268 aa - 268 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8572+/-0.000826; mu= 8.9904+/- 0.050 mean_var=107.9156+/-21.545, 0's: 0 Z-trim(109.8): 8 B-trim: 0 in 0/51 Lambda= 0.123462 statistics sampled from 11167 (11174) to 11167 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.343), width: 16 Scan time: 1.670 The best scores are: opt bits E(32554) CCDS13208.1 MAPRE1 gene_id:22919|Hs108|chr20 ( 268) 1777 326.6 1.1e-89 CCDS45851.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 284) 1018 191.4 5.9e-49 CCDS45850.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 315) 1018 191.4 6.5e-49 CCDS11910.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 327) 1018 191.4 6.7e-49 CCDS1731.1 MAPRE3 gene_id:22924|Hs108|chr2 ( 281) 885 167.7 7.9e-42 CCDS58619.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 274) 827 157.4 1e-38 >>CCDS13208.1 MAPRE1 gene_id:22919|Hs108|chr20 (268 aa) initn: 1777 init1: 1777 opt: 1777 Z-score: 1723.4 bits: 326.6 E(32554): 1.1e-89 Smith-Waterman score: 1777; 100.0% identity (100.0% similar) in 268 aa overlap (1-268:1-268) 10 20 30 40 50 60 pF1KB8 MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GKDYDPVAARQGQETAVAPSLVAPALNKPKKPLTSSSAAPQRPISTQRTAAAPKAGPGVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GKDYDPVAARQGQETAVAPSLVAPALNKPKKPLTSSSAAPQRPISTQRTAAAPKAGPGVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RKNPGVGNGDDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 RKNPGVGNGDDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQ 190 200 210 220 230 240 250 260 pF1KB8 RIVDILYATDEGFVIPDEGGPQEEQEEY :::::::::::::::::::::::::::: CCDS13 RIVDILYATDEGFVIPDEGGPQEEQEEY 250 260 >>CCDS45851.1 MAPRE2 gene_id:10982|Hs108|chr18 (284 aa) initn: 1007 init1: 784 opt: 1018 Z-score: 992.3 bits: 191.4 E(32554): 5.9e-49 Smith-Waterman score: 1018; 56.3% identity (78.3% similar) in 277 aa overlap (1-267:1-270) 10 20 30 40 50 60 pF1KB8 MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKK :::::::::.:....::::..::.:. ..:: ::.::::::::::::::::::: :.::: CCDS45 MAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYD ::::::::::::.:::.:::.::::.:::.:::.:::::.::::..:.::::::.::::: CCDS45 VKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYD 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 GKDYDPVAARQGQETAVAPSLVAPALNKPKKPLTSSSAAPQRPISTQRTAAAPKAGPG-- ::.:::: :::::.. :. .: ::: ..: : . . :: : . :. CCDS45 GKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANS--PTAGAAKSSPAAKPGSTPSRP 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 -VVRKNPGVGNG-------DDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQE ... . :.. . .. .: .::. :::..: .::::::::::::.:::.::: CCDS45 SSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQE 180 190 200 210 220 230 240 250 260 pF1KB8 NEGENDPVLQRIVDILYATDEGFVIPDEGGPQEEQEEY . ::: ..::..:::::..: :: .: . : CCDS45 HGQENDDLVQRLMDILYASEE-----HEGHTEEPEAEEQAHEQQPPQQEEY 240 250 260 270 280 >>CCDS45850.1 MAPRE2 gene_id:10982|Hs108|chr18 (315 aa) initn: 1007 init1: 784 opt: 1018 Z-score: 991.7 bits: 191.4 E(32554): 6.5e-49 Smith-Waterman score: 1018; 56.3% identity (78.3% similar) in 277 aa overlap (1-267:32-301) 10 20 30 pF1KB8 MAVNVYSTSVTSDNLSRHDMLAWINESLQL :::::::::.:....::::..::.:. ..: CCDS45 KQNRDQKCPVSQRNSSFQQPGRKPGCSSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 NLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQAKLEHEYIQNFKILQAGFKRMGVDKI : ::.::::::::::::::::::: :.:::::::::::::::.:::.:::.::::.:::. CCDS45 NYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 IPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKDYDPVAARQGQETAVAPSLVAPALNKPK :::.:::::.::::..:.::::::.:::::::.:::: :::::.. :. .: :: CCDS45 IPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPK 130 140 150 160 170 180 160 170 180 190 200 pF1KB8 KPLTSSSAAPQRPISTQRTAAAPKAGPG---VVRKNPGVGNG-------DDEAAELMQQV : ..: : . . :: : . :. ... . :.. . .. .: .:: CCDS45 KSHHANS--PTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQV 190 200 210 220 230 210 220 230 240 250 260 pF1KB8 NVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGFVIPDEGG . :::..: .::::::::::::.:::.:::. ::: ..::..:::::..: :: CCDS45 HSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEE-----HEGH 240 250 260 270 280 290 pF1KB8 PQEEQEEY .: . : CCDS45 TEEPEAEEQAHEQQPPQQEEY 300 310 >>CCDS11910.1 MAPRE2 gene_id:10982|Hs108|chr18 (327 aa) initn: 1007 init1: 784 opt: 1018 Z-score: 991.4 bits: 191.4 E(32554): 6.7e-49 Smith-Waterman score: 1018; 56.3% identity (78.3% similar) in 277 aa overlap (1-267:44-313) 10 20 30 pF1KB8 MAVNVYSTSVTSDNLSRHDMLAWINESLQL :::::::::.:....::::..::.:. ..: CCDS11 NNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 NLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQAKLEHEYIQNFKILQAGFKRMGVDKI : ::.::::::::::::::::::: :.:::::::::::::::.:::.:::.::::.:::. CCDS11 NYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKV 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 IPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKDYDPVAARQGQETAVAPSLVAPALNKPK :::.:::::.::::..:.::::::.:::::::.:::: :::::.. :. .: :: CCDS11 IPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPK 140 150 160 170 180 190 160 170 180 190 200 pF1KB8 KPLTSSSAAPQRPISTQRTAAAPKAGPG---VVRKNPGVGNG-------DDEAAELMQQV : ..: : . . :: : . :. ... . :.. . .. .: .:: CCDS11 KSHHANS--PTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQV 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB8 NVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGFVIPDEGG . :::..: .::::::::::::.:::.:::. ::: ..::..:::::..: :: CCDS11 HSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEE-----HEGH 260 270 280 290 300 pF1KB8 PQEEQEEY .: . : CCDS11 TEEPEAEEQAHEQQPPQQEEY 310 320 >>CCDS1731.1 MAPRE3 gene_id:22924|Hs108|chr2 (281 aa) initn: 1157 init1: 838 opt: 885 Z-score: 864.4 bits: 167.7 E(32554): 7.9e-42 Smith-Waterman score: 1159; 65.4% identity (81.6% similar) in 283 aa overlap (1-268:1-281) 10 20 30 40 50 60 pF1KB8 MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKK ::::::::::::.::::::::::.:.::.:: :::::::::::::::::::::: . :.: CCDS17 MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYD ::::::::::::.:::.:::.::.:::::::::.:::::::::::::.:::::::::::: CCDS17 VKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYD 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 GKDYDPVAARQGQETAVAPSLVAPALNKPKKPLTSSSAAPQR-----PISTQRTAAAPK- ::::.:. :::::..: :. .:: :: . ..:.::: : . : .. . CCDS17 GKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLI--GTAVPQRTSPTGPKNMQTSGRLSNV 130 140 150 160 170 180 190 200 210 220 pF1KB8 AGPGVVRKNP-GVGNG----DDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQ : : ..:::: .. :: : . :: ::. :::::. :::::::::.:::.:::::: CCDS17 APPCILRKNPPSARNGGHETDAQILELNQQLVDLKLTVDGLEKERDFYFSKLRDIELICQ 180 190 200 210 220 230 230 240 250 260 pF1KB8 ENEGENDPVLQRIVDILYATDEGFVIPD----EGGPQEEQEEY :.:.::.::.. :. :::::.:::. :. : ::.:.:: CCDS17 EHESENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY 240 250 260 270 280 >>CCDS58619.1 MAPRE2 gene_id:10982|Hs108|chr18 (274 aa) initn: 816 init1: 593 opt: 827 Z-score: 808.7 bits: 157.4 E(32554): 1e-38 Smith-Waterman score: 827; 54.2% identity (75.6% similar) in 238 aa overlap (40-267:30-260) 10 20 30 40 50 60 pF1KB8 VTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQAKLEH .:::::::::::::: :.:::::::::::: CCDS58 MARTTTTSSRIITGPSFLSGSTQCAGSVPTGAAYCQFMDMLFPGCISLKKVKFQAKLEH 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 EYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKDYDPVAA :::.:::.:::.::::.:::.:::.:::::.::::..:.::::::.:::::::.:::: : CCDS58 EYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RQGQETAVAPSLVAPALNKPKKPLTSSSAAPQRPISTQRTAAAPKAGPG---VVRKNPGV ::::.. :. .: ::: . . .: . . :: : . :. ... . CCDS58 RQGQDAIPPPDPGEQIFNLPKK--SHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSS 120 130 140 150 160 170 190 200 210 220 230 pF1KB8 GNG-------DDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVL :.. . .. .: .::. :::..: .::::::::::::.:::.:::. ::: .. CCDS58 GSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLV 180 190 200 210 220 230 240 250 260 pF1KB8 QRIVDILYATDEGFVIPDEGGPQEEQEEY ::..:::::..: :: .: . : CCDS58 QRLMDILYASEE-----HEGHTEEPEAEEQAHEQQPPQQEEY 240 250 260 270 268 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:00:12 2016 done: Fri Nov 4 10:00:12 2016 Total Scan time: 1.670 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]