FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8150, 479 aa 1>>>pF1KB8150 479 - 479 aa - 479 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0107+/-0.00088; mu= 14.7146+/- 0.053 mean_var=76.9749+/-15.038, 0's: 0 Z-trim(106.8): 29 B-trim: 0 in 0/51 Lambda= 0.146184 statistics sampled from 9181 (9209) to 9181 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.283), width: 16 Scan time: 2.180 The best scores are: opt bits E(32554) CCDS1817.1 PPM1B gene_id:5495|Hs108|chr2 ( 479) 3190 682.3 3e-196 CCDS1816.1 PPM1B gene_id:5495|Hs108|chr2 ( 387) 2570 551.5 5.8e-157 CCDS46271.1 PPM1B gene_id:5495|Hs108|chr2 ( 380) 2562 549.8 1.8e-156 CCDS9744.1 PPM1A gene_id:5494|Hs108|chr14 ( 382) 1983 427.7 1.1e-119 CCDS45120.1 PPM1A gene_id:5494|Hs108|chr14 ( 455) 1983 427.7 1.2e-119 CCDS9745.1 PPM1A gene_id:5494|Hs108|chr14 ( 324) 1717 371.6 7e-103 CCDS1818.1 PPM1B gene_id:5495|Hs108|chr2 ( 192) 1223 267.3 1e-71 CCDS46115.1 PPM1N gene_id:147699|Hs108|chr19 ( 430) 847 188.1 1.5e-47 CCDS1752.1 PPM1G gene_id:5496|Hs108|chr2 ( 546) 393 92.4 1.3e-18 CCDS2526.1 ILKAP gene_id:80895|Hs108|chr2 ( 392) 390 91.8 1.5e-18 CCDS82868.1 PPM1L gene_id:151742|Hs108|chr3 ( 233) 365 86.4 3.6e-17 CCDS33886.1 PPM1L gene_id:151742|Hs108|chr3 ( 360) 365 86.5 5.3e-17 CCDS82869.1 PPM1L gene_id:151742|Hs108|chr3 ( 181) 351 83.4 2.2e-16 CCDS11613.1 PPM1E gene_id:22843|Hs108|chr17 ( 755) 299 72.7 1.6e-12 CCDS3629.1 PPM1K gene_id:152926|Hs108|chr4 ( 372) 284 69.4 7.5e-12 CCDS13796.1 PPM1F gene_id:9647|Hs108|chr22 ( 454) 278 68.2 2.2e-11 >>CCDS1817.1 PPM1B gene_id:5495|Hs108|chr2 (479 aa) initn: 3190 init1: 3190 opt: 3190 Z-score: 3636.7 bits: 682.3 E(32554): 3e-196 Smith-Waterman score: 3190; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479) 10 20 30 40 50 60 pF1KB8 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 AKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 AKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI 430 440 450 460 470 >>CCDS1816.1 PPM1B gene_id:5495|Hs108|chr2 (387 aa) initn: 2570 init1: 2570 opt: 2570 Z-score: 2931.5 bits: 551.5 E(32554): 5.8e-157 Smith-Waterman score: 2570; 98.4% identity (99.5% similar) in 385 aa overlap (1-385:1-385) 10 20 30 40 50 60 pF1KB8 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL ::::::::::::::::::.. . :. CCDS18 NVIEAVYSRLNPHRESDGGAGDLEDPW 370 380 >>CCDS46271.1 PPM1B gene_id:5495|Hs108|chr2 (380 aa) initn: 2562 init1: 2562 opt: 2562 Z-score: 2922.5 bits: 549.8 E(32554): 1.8e-156 Smith-Waterman score: 2562; 100.0% identity (100.0% similar) in 378 aa overlap (1-378:1-378) 10 20 30 40 50 60 pF1KB8 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL :::::::::::::::::: CCDS46 NVIEAVYSRLNPHRESDGQK 370 380 >>CCDS9744.1 PPM1A gene_id:5494|Hs108|chr14 (382 aa) initn: 1940 init1: 892 opt: 1983 Z-score: 2262.5 bits: 427.7 E(32554): 1.1e-119 Smith-Waterman score: 1983; 75.9% identity (90.4% similar) in 386 aa overlap (1-385:1-380) 10 20 30 40 50 60 pF1KB8 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD ::::::::: :::::.: :::::::::::::::::::::::::.:.: :::.:::::::: CCDS97 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF :::::.::.:: :::.:::.:.::. ::: ::::::::::::::.:::.:: . CCDS97 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI :. ..: ::::::::::.:::.: :::::::::..: :: .: : :::::: :: ::::: CCDS97 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 120 130 140 150 160 170 190 200 210 220 230 pF1KB8 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDE-FII ::::::::::::::::::::::::.::::: :::::::::::::::..: :.:::. ::: CCDS97 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP ::::::::::.:::::..:.:::::.::::.::: ::::::.::::::::..:.:: ::: CCDS97 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGK ::: :::::..::::.:: :::::..:.:: :.:::.:::: :..::::.::::: ::.: CCDS97 KVSPEAVKKEAELDKYLECRVEEIIKKQGE-GVPDLVHVMRTLASENIPSLPPGGELASK 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 RNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYR ::::::::.::::....: : ... CCDS97 RNVIEAVYNRLNPYKNDDTDSTSTDDMW 360 370 380 >>CCDS45120.1 PPM1A gene_id:5494|Hs108|chr14 (455 aa) initn: 1918 init1: 892 opt: 1983 Z-score: 2261.4 bits: 427.7 E(32554): 1.2e-119 Smith-Waterman score: 1983; 75.9% identity (90.4% similar) in 386 aa overlap (1-385:74-453) 10 20 30 pF1KB8 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQ ::::::::: :::::.: :::::::::::: CCDS45 ERRRNEKRGNQMKRMCERKKYETDLEDQDIMGAFLDKPKMEKHNAQGQGNGLRYGLSSMQ 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB8 GWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGK :::::::::::::.:.: :::.:::::::::::::.::.:: :::.:::.:.::. CCDS45 GWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFK---- 110 120 130 140 150 100 110 120 130 140 150 pF1KB8 SGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCG ::: ::::::::::::::.:::.:: .:. ..: ::::::::::.:::.: :::::: CCDS45 -GSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCG 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB8 DSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCV :::..: :: .: : :::::: :: :::::::::::::::::::::::::::::.::::: CCDS45 DSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCV 220 230 240 250 260 270 220 230 240 250 260 pF1KB8 DGKGPTEQLVSPEPEVYEILRAEEDE-FIILACDGIWDVMSNEELCEYVKSRLEVSDDLE :::::::::::::::..: :.:::. :::::::::::::.:::::..:.:::::.:::: CCDS45 HGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLE 280 290 300 310 320 330 270 280 290 300 310 320 pF1KB8 NVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGE .::: ::::::.::::::::..:.:: :::::: :::::..::::.:: :::::..:.:: CCDS45 KVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEIIKKQGE 340 350 360 370 380 390 330 340 350 360 370 380 pF1KB8 EGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQ :.:::.:::: :..::::.::::: ::.:::::::::.::::....: : ... CCDS45 -GVPDLVHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW 400 410 420 430 440 450 390 400 410 420 430 440 pF1KB8 GKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTM >>CCDS9745.1 PPM1A gene_id:5494|Hs108|chr14 (324 aa) initn: 1280 init1: 753 opt: 1717 Z-score: 1960.5 bits: 371.6 E(32554): 7e-103 Smith-Waterman score: 1717; 78.6% identity (90.7% similar) in 322 aa overlap (1-321:1-317) 10 20 30 40 50 60 pF1KB8 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD ::::::::: :::::.: :::::::::::::::::::::::::.:.: :::.:::::::: CCDS97 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF :::::.::.:: :::.:::.:.::. ::: ::::::::::::::.:::.:: . CCDS97 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI :. ..: ::::::::::.:::.: :::::::::..: :: .: : :::::: :: ::::: CCDS97 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 120 130 140 150 160 170 190 200 210 220 230 pF1KB8 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDE-FII ::::::::::::::::::::::::.::::: :::::::::::::::..: :.:::. ::: CCDS97 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP ::::::::::.:::::..:.:::::.::::.::: ::::::.::::::::..:.:: ::: CCDS97 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGK ::: :::::..::::.:: ::: CCDS97 KVSPEAVKKEAELDKYLECRVEGGSFNKK 300 310 320 >>CCDS1818.1 PPM1B gene_id:5495|Hs108|chr2 (192 aa) initn: 1223 init1: 1223 opt: 1223 Z-score: 1401.0 bits: 267.3 E(32554): 1e-71 Smith-Waterman score: 1223; 100.0% identity (100.0% similar) in 192 aa overlap (288-479:1-192) 260 270 280 290 300 310 pF1KB8 VKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKHLE :::::::::::::::::::::::::::::: CCDS18 MSIVLVCFSNAPKVSDEAVKKDSELDKHLE 10 20 30 320 330 340 350 360 370 pF1KB8 SRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 SRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESD 40 50 60 70 80 90 380 390 400 410 420 430 pF1KB8 GASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 GASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATAT 100 110 120 130 140 150 440 450 460 470 pF1KB8 SSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI :::::::::::::::::::::::::::::::::::::::::: CCDS18 SSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI 160 170 180 190 >>CCDS46115.1 PPM1N gene_id:147699|Hs108|chr19 (430 aa) initn: 951 init1: 674 opt: 847 Z-score: 966.9 bits: 188.1 E(32554): 1.5e-47 Smith-Waterman score: 1035; 43.6% identity (68.5% similar) in 390 aa overlap (3-390:44-413) 10 20 30 pF1KB8 MGAFLDKPKTEK--HNAHGAGNGLRYGLSSMQ ..: :. . :.. :..:::.: :. : CCDS46 TACKKKEREKEGREEEEEEEAGRRAPEGPRSLLTAPRRAQRPHGGAEASGGLRFGASAAQ 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 GWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGK :::..::::: . ...: :..::: :::.:.:.: . . :: :. .. : CCDS46 GWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGARHLPGHV-----LQELGP 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 SGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCG : :.:....: .::. :: .:. : .. .: ::: ...::. .:. .:: CCDS46 EPSE----PEGVREALRRAFLSADERLRS---LWPRVETGGCTAVVLLVSPRFLYLAHCG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 DSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCV :::::: : : : :::.::.: :::.:::. :::.. .::.:::::::::::. :: . CCDS46 DSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 DGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDDLEN :. : :::: :::: . : ::::..:: ::.::..:. : : :::... : CCDS46 PGRPPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPEL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 VCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEE .: ..:::: ::: :::. .:::: .::. :.::.... :: : :. :. .. . CCDS46 LCAQLLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELALDAALGCRIAELCASAQKP 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 GMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQG :.: :.: :..:.::.::::::: : .:: :::.. .:.: :.:..: CCDS46 --PSLNTVFRTLASEDIPDLPPGGGLDCKATVIAEVYSQICQ------VSEECGEKGQDG 370 380 390 400 410 400 410 420 430 440 450 pF1KB8 KLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQ CCDS46 AGKSNPTHLGSALDMEA 420 430 >>CCDS1752.1 PPM1G gene_id:5496|Hs108|chr2 (546 aa) initn: 589 init1: 233 opt: 393 Z-score: 447.8 bits: 92.4 E(32554): 1.3e-18 Smith-Waterman score: 429; 34.4% identity (63.3% similar) in 218 aa overlap (126-330:324-532) 100 110 120 130 140 150 pF1KB8 ELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAV : : ::.::: ..: :.. : :::: : CCDS17 DEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSD-SGTTAVVALIRGKQLIVANAGDSRCV 300 310 320 330 340 350 160 170 180 190 200 210 pF1KB8 LYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ-RVNGSLAVSRALGDYDYKCVDGKG . . :.. . :::: . : ::.::::.: .. ::::.: .:::.::. :: . CCDS17 VSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLP 360 370 380 390 400 410 220 230 240 250 260 pF1KB8 PTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDD------L : ::..: :.. . ... ::...::::::.:::..:. ....:.. :. : CCDS17 PEEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLL 420 430 440 450 460 470 270 280 290 300 310 320 pF1KB8 ENVCNWVVDTCLHKGSR------DNMSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEE .. . ..: :: . :::. ...::. :. . : .. .: . ..:: CCDS17 SSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK--PRNTAE-LQPESG-----KRKLEE 480 490 500 510 520 330 340 350 360 370 380 pF1KB8 IMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDE .. : : CCDS17 VLSTEGAEENGNSDKKKKAKRD 530 540 >>CCDS2526.1 ILKAP gene_id:80895|Hs108|chr2 (392 aa) initn: 402 init1: 132 opt: 390 Z-score: 446.7 bits: 91.8 E(32554): 1.5e-18 Smith-Waterman score: 390; 32.2% identity (61.1% similar) in 301 aa overlap (21-293:106-388) 10 20 30 40 pF1KB8 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGI---- ::. .. .: : ::.:::. . : CCDS25 GAKRKTSEEEKNGSEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITEEC 80 90 100 110 120 130 50 60 70 80 90 100 pF1KB8 --PHGL-EDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVEN-V : .: :.:::.:::.: :.... . .: ... .: : :.. .:::. : CCDS25 RPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNL-----IRKFPK-GDV--ISVEKTV 140 150 160 170 180 110 120 130 140 150 160 pF1KB8 KNGIRTGFLKIDE-YMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQ : . : . :: .... :. . . ..::::. :. . .:. : :::::.: : .. CCDS25 KRCLLDTFKHTDEEFLKQASSQKPAW-KDGSTATCVLAVDNILYIANLGDSRAILCRYNE 190 200 210 220 230 240 170 180 190 200 210 pF1KB8 -----VCFS-TQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYK-CVDGKG . .: ...:.: . .:. :::.:::.: :: : : :::..:: .:: : : CCDS25 ESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRC--G-- 250 260 270 280 290 300 220 230 240 250 260 pF1KB8 PTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLE----------- :. :.. . . .:.::.:::::.. :.. :: ... : :: CCDS25 -----VTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKS 310 320 330 340 350 270 280 290 300 310 320 pF1KB8 VSDD-LENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEE ..: : .:: ... ...:: ::.....: CCDS25 AADARYEAACNRLANKAVQRGSADNVTVMVVRIGH 360 370 380 390 330 340 350 360 370 380 pF1KB8 IMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDE 479 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:01:17 2016 done: Fri Nov 4 10:01:17 2016 Total Scan time: 2.180 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]