FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8157, 549 aa 1>>>pF1KB8157 549 - 549 aa - 549 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7878+/-0.000927; mu= 8.2863+/- 0.056 mean_var=149.7884+/-29.376, 0's: 0 Z-trim(110.8): 16 B-trim: 0 in 0/51 Lambda= 0.104794 statistics sampled from 11872 (11881) to 11872 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.365), width: 16 Scan time: 3.240 The best scores are: opt bits E(32554) CCDS2861.1 GNL3 gene_id:26354|Hs108|chr3 ( 549) 3571 551.7 8.2e-157 CCDS43100.1 GNL3 gene_id:26354|Hs108|chr3 ( 537) 3495 540.2 2.3e-153 CCDS14360.1 GNL3L gene_id:54552|Hs108|chrX ( 582) 970 158.5 2.1e-38 >>CCDS2861.1 GNL3 gene_id:26354|Hs108|chr3 (549 aa) initn: 3571 init1: 3571 opt: 3571 Z-score: 2928.7 bits: 551.7 E(32554): 8.2e-157 Smith-Waterman score: 3571; 99.5% identity (100.0% similar) in 549 aa overlap (1-549:1-549) 10 20 30 40 50 60 pF1KB8 MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKQGHKKPRKDPGVPNSAPFKEAL ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: CCDS28 MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 SLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFILDKIIEEDD :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS28 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDD 490 500 510 520 530 540 pF1KB8 AYDFSTDYV ::::::::: CCDS28 AYDFSTDYV >>CCDS43100.1 GNL3 gene_id:26354|Hs108|chr3 (537 aa) initn: 3495 init1: 3495 opt: 3495 Z-score: 2866.8 bits: 540.2 E(32554): 2.3e-153 Smith-Waterman score: 3495; 99.4% identity (100.0% similar) in 537 aa overlap (13-549:1-537) 10 20 30 40 50 60 pF1KB8 MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKQGHKKPRKDPGVPNSAPFKEAL ::::::::::::::::::::::::::.::::::::::::::::::::: CCDS43 MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL 10 20 30 40 70 80 90 100 110 120 pF1KB8 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 SLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB8 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB8 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFILDKIIEEDD :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS43 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDD 470 480 490 500 510 520 pF1KB8 AYDFSTDYV ::::::::: CCDS43 AYDFSTDYV 530 >>CCDS14360.1 GNL3L gene_id:54552|Hs108|chrX (582 aa) initn: 887 init1: 384 opt: 970 Z-score: 803.1 bits: 158.5 E(32554): 2.1e-38 Smith-Waterman score: 970; 37.5% identity (69.8% similar) in 437 aa overlap (16-443:6-441) 10 20 30 40 50 pF1KB8 MKRPKLKKASKRMTCHKRYKIQKKVREHHR---KLRKEAKKQGHKKPRKDPGVPNSAPFK :: : . . :.. . ::..:.: : :..:. . . CCDS14 MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPN 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 EALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETN-PDIKPSNVEPMEKEFGLCKTE . :::::.:. .::....:. :..: .:.: .:. :. . : .:: : . . CCDS14 DHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 NKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVL . . ..: : .:..::.: :::.:::::::::::::: :.:::.... :.::::: CCDS14 MFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 ILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPF-RSEVC .::: :::::: .:.::.::..:::::.:.:::. . :. : . . . . .:..: CCDS14 VLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKAC 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 FGKEGLWKLLGGFQET--CSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSM :: :.: ..::.. . :::::.:.:::::::.:::::. . :.::. :.:. : CCDS14 FGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFM 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 QVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIE-VVKPMEAASAILSQADARQVVL : : ::: : ..:.:... .: :: . ::. . .. .. :. . .::.. . ... CCDS14 QEVYLDKFIRLLDAPGIVPGP-NSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISN 300 310 320 330 340 360 370 380 390 400 410 pF1KB8 KYTVPGYRNSLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTP : : :.... .:.: .:.: : ..:::. . : ::: . ..:.......: ::.. : CCDS14 YYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTL 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB8 PPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHE : ... :: .: :..:. :. : .... . CCDS14 PTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTK 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB8 ELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFI CCDS14 IADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRI 470 480 490 500 510 520 549 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:05:09 2016 done: Fri Nov 4 10:05:10 2016 Total Scan time: 3.240 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]