FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8165, 496 aa
1>>>pF1KB8165 496 - 496 aa - 496 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.6751+/-0.000584; mu= -24.3970+/- 0.035
mean_var=614.2394+/-135.126, 0's: 0 Z-trim(116.8): 1493 B-trim: 578 in 1/55
Lambda= 0.051749
statistics sampled from 26126 (28321) to 26126 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.332), width: 16
Scan time: 8.650
The best scores are: opt bits E(85289)
XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 3262 259.4 1.8e-68
XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 3262 259.4 1.8e-68
XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 3262 259.4 1.8e-68
NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 3262 259.4 1.8e-68
XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 3262 259.4 1.8e-68
NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 3262 259.4 1.8e-68
XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 3262 259.4 1.9e-68
NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 3262 259.4 2e-68
XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 3180 253.2 1.2e-66
XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 3180 253.3 1.3e-66
XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 3180 253.3 1.3e-66
XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 3180 253.3 1.4e-66
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 2318 188.9 3e-47
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 2318 188.9 3e-47
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 2318 188.9 3e-47
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 2318 188.9 3e-47
NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1982 163.8 1e-39
NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1982 163.8 1e-39
XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 1982 163.8 1.1e-39
NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 1958 162.0 3.6e-39
XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 1958 162.1 4e-39
XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 1237 108.1 5.1e-23
XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 1237 108.1 5.4e-23
NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 1237 108.1 5.4e-23
XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 1237 108.1 5.5e-23
NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469) 1237 108.1 5.5e-23
XP_016874896 (OMIM: 603440) PREDICTED: cyclin-depe ( 502) 1217 106.7 1.6e-22
XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384) 1174 103.4 1.3e-21
NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384) 1174 103.4 1.3e-21
XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435) 1174 103.4 1.4e-21
NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429) 1149 101.5 4.9e-21
XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412) 1146 101.3 5.6e-21
NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400) 1141 100.9 7.1e-21
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 1133 100.2 8.6e-21
NP_001274066 (OMIM: 610679) cyclin-dependent kinas ( 340) 1104 98.1 4.3e-20
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 1082 96.4 1.2e-19
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 1062 94.9 3.4e-19
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 1056 94.4 4.7e-19
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 1056 94.4 4.7e-19
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 1056 94.4 4.7e-19
>>XP_016885062 (OMIM: 311550) PREDICTED: cyclin-dependen (496 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 1350.4 bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
430 440 450 460 470 480
490
pF1KB8 MPDSGRPAFRVVDTEF
::::::::::::::::
XP_016 MPDSGRPAFRVVDTEF
490
>>XP_016885061 (OMIM: 311550) PREDICTED: cyclin-dependen (496 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 1350.4 bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
430 440 450 460 470 480
490
pF1KB8 MPDSGRPAFRVVDTEF
::::::::::::::::
XP_016 MPDSGRPAFRVVDTEF
490
>>XP_016885060 (OMIM: 311550) PREDICTED: cyclin-dependen (496 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 1350.4 bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
430 440 450 460 470 480
490
pF1KB8 MPDSGRPAFRVVDTEF
::::::::::::::::
XP_016 MPDSGRPAFRVVDTEF
490
>>NP_006192 (OMIM: 311550) cyclin-dependent kinase 16 is (496 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 1350.4 bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
430 440 450 460 470 480
490
pF1KB8 MPDSGRPAFRVVDTEF
::::::::::::::::
NP_006 MPDSGRPAFRVVDTEF
490
>>XP_016885059 (OMIM: 311550) PREDICTED: cyclin-dependen (496 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 1350.4 bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
430 440 450 460 470 480
490
pF1KB8 MPDSGRPAFRVVDTEF
::::::::::::::::
XP_016 MPDSGRPAFRVVDTEF
490
>>NP_148978 (OMIM: 311550) cyclin-dependent kinase 16 is (502 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 1350.3 bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:7-502)
10 20 30 40 50
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 MQSEIAMDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 ELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 NKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 NKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 TYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 TYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 SLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 SLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 MATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 MATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 LDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 LDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEA
430 440 450 460 470 480
480 490
pF1KB8 SLRSSSMPDSGRPAFRVVDTEF
::::::::::::::::::::::
NP_148 SLRSSSMPDSGRPAFRVVDTEF
490 500
>>XP_016885058 (OMIM: 311550) PREDICTED: cyclin-dependen (543 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 1349.9 bits: 259.4 E(85289): 1.9e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:48-543)
10 20 30
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQ
::::::::::::::::::::::::::::::
XP_016 SHYSRSSGYSRDLNTEIYPGGADLLVVAIAMDRMKKIKRQLSMTLRGGRGIDKTNGAPEQ
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 IGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB8 DEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLR
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB8 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB8 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQL
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB8 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB8 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB8 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG
440 450 460 470 480 490
460 470 480 490
pF1KB8 ERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
500 510 520 530 540
>>NP_001163931 (OMIM: 311550) cyclin-dependent kinase 16 (570 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 1349.6 bits: 259.4 E(85289): 2e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:75-570)
10 20 30
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQ
::::::::::::::::::::::::::::::
NP_001 CSGAFPLDPNNPSLGPLPSISHLNLRTQIAMDRMKKIKRQLSMTLRGGRGIDKTNGAPEQ
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB8 IGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSS
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB8 DEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLR
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB8 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR
230 240 250 260 270 280
220 230 240 250 260 270
pF1KB8 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQL
290 300 310 320 330 340
280 290 300 310 320 330
pF1KB8 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP
350 360 370 380 390 400
340 350 360 370 380 390
pF1KB8 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL
410 420 430 440 450 460
400 410 420 430 440 450
pF1KB8 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG
470 480 490 500 510 520
460 470 480 490
pF1KB8 ERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
530 540 550 560 570
>>XP_011542229 (OMIM: 311550) PREDICTED: cyclin-dependen (497 aa)
initn: 3180 init1: 3180 opt: 3180 Z-score: 1317.3 bits: 253.2 E(85289): 1.2e-66
Smith-Waterman score: 3180; 100.0% identity (100.0% similar) in 484 aa overlap (1-484:1-484)
10 20 30 40 50 60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
430 440 450 460 470 480
490
pF1KB8 MPDSGRPAFRVVDTEF
::::
XP_011 MPDSVAGGQHGRASLPH
490
>>XP_011542230 (OMIM: 311550) PREDICTED: cyclin-dependen (497 aa)
initn: 3180 init1: 3180 opt: 3180 Z-score: 1317.3 bits: 253.2 E(85289): 1.2e-66
Smith-Waterman score: 3180; 100.0% identity (100.0% similar) in 484 aa overlap (1-484:1-484)
10 20 30 40 50 60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
430 440 450 460 470 480
490
pF1KB8 MPDSGRPAFRVVDTEF
::::
XP_011 MPDSVAGGQHGRASLPH
490
496 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:09:52 2016 done: Fri Nov 4 10:09:54 2016
Total Scan time: 8.650 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]