Result of FASTA (omim) for pF1KB8165
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8165, 496 aa
  1>>>pF1KB8165 496 - 496 aa - 496 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.6751+/-0.000584; mu= -24.3970+/- 0.035
 mean_var=614.2394+/-135.126, 0's: 0 Z-trim(116.8): 1493  B-trim: 578 in 1/55
 Lambda= 0.051749
 statistics sampled from 26126 (28321) to 26126 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.332), width:  16
 Scan time:  8.650

The best scores are:                                      opt bits E(85289)
XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 3262 259.4 1.8e-68
XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 3262 259.4 1.8e-68
XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 3262 259.4 1.8e-68
NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 3262 259.4 1.8e-68
XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 3262 259.4 1.8e-68
NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 3262 259.4 1.8e-68
XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 3262 259.4 1.9e-68
NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 3262 259.4   2e-68
XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 3180 253.2 1.2e-66
XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 3180 253.2 1.2e-66
XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 3180 253.3 1.3e-66
XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 3180 253.3 1.3e-66
XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 3180 253.3 1.4e-66
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 2318 188.9   3e-47
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 2318 188.9   3e-47
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 2318 188.9   3e-47
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 2318 188.9   3e-47
NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1982 163.8   1e-39
NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1982 163.8   1e-39
XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 1982 163.8 1.1e-39
NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 1958 162.0 3.6e-39
XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 1958 162.1   4e-39
XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 1237 108.1 5.1e-23
XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1237 108.1 5.1e-23
XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 1237 108.1 5.4e-23
NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 1237 108.1 5.4e-23
XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 1237 108.1 5.5e-23
NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469) 1237 108.1 5.5e-23
XP_016874896 (OMIM: 603440) PREDICTED: cyclin-depe ( 502) 1217 106.7 1.6e-22
XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384) 1174 103.4 1.3e-21
NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384) 1174 103.4 1.3e-21
XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435) 1174 103.4 1.4e-21
NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429) 1149 101.5 4.9e-21
XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412) 1146 101.3 5.6e-21
NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400) 1141 100.9 7.1e-21
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 1133 100.2 8.6e-21
NP_001274066 (OMIM: 610679) cyclin-dependent kinas ( 340) 1104 98.1 4.3e-20
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 1082 96.4 1.2e-19
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 1062 94.9 3.4e-19
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 1056 94.4 4.7e-19
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 1056 94.4 4.7e-19
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 1056 94.4 4.7e-19


>>XP_016885062 (OMIM: 311550) PREDICTED: cyclin-dependen  (496 aa)
 initn: 3262 init1: 3262 opt: 3262  Z-score: 1350.4  bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)

               10        20        30        40        50        60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
              430       440       450       460       470       480

              490      
pF1KB8 MPDSGRPAFRVVDTEF
       ::::::::::::::::
XP_016 MPDSGRPAFRVVDTEF
              490      

>>XP_016885061 (OMIM: 311550) PREDICTED: cyclin-dependen  (496 aa)
 initn: 3262 init1: 3262 opt: 3262  Z-score: 1350.4  bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)

               10        20        30        40        50        60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
              430       440       450       460       470       480

              490      
pF1KB8 MPDSGRPAFRVVDTEF
       ::::::::::::::::
XP_016 MPDSGRPAFRVVDTEF
              490      

>>XP_016885060 (OMIM: 311550) PREDICTED: cyclin-dependen  (496 aa)
 initn: 3262 init1: 3262 opt: 3262  Z-score: 1350.4  bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)

               10        20        30        40        50        60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
              430       440       450       460       470       480

              490      
pF1KB8 MPDSGRPAFRVVDTEF
       ::::::::::::::::
XP_016 MPDSGRPAFRVVDTEF
              490      

>>NP_006192 (OMIM: 311550) cyclin-dependent kinase 16 is  (496 aa)
 initn: 3262 init1: 3262 opt: 3262  Z-score: 1350.4  bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)

               10        20        30        40        50        60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
              430       440       450       460       470       480

              490      
pF1KB8 MPDSGRPAFRVVDTEF
       ::::::::::::::::
NP_006 MPDSGRPAFRVVDTEF
              490      

>>XP_016885059 (OMIM: 311550) PREDICTED: cyclin-dependen  (496 aa)
 initn: 3262 init1: 3262 opt: 3262  Z-score: 1350.4  bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)

               10        20        30        40        50        60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
              430       440       450       460       470       480

              490      
pF1KB8 MPDSGRPAFRVVDTEF
       ::::::::::::::::
XP_016 MPDSGRPAFRVVDTEF
              490      

>>NP_148978 (OMIM: 311550) cyclin-dependent kinase 16 is  (502 aa)
 initn: 3262 init1: 3262 opt: 3262  Z-score: 1350.3  bits: 259.4 E(85289): 1.8e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:7-502)

                     10        20        30        40        50    
pF1KB8       MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPG
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 MQSEIAMDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPG
               10        20        30        40        50        60

           60        70        80        90       100       110    
pF1KB8 ELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 ELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDI
               70        80        90       100       110       120

          120       130       140       150       160       170    
pF1KB8 NKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 NKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEG
              130       140       150       160       170       180

          180       190       200       210       220       230    
pF1KB8 TYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 TYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEK
              190       200       210       220       230       240

          240       250       260       270       280       290    
pF1KB8 SLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 SLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI
              250       260       270       280       290       300

          300       310       320       330       340       350    
pF1KB8 NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYE
              310       320       330       340       350       360

          360       370       380       390       400       410    
pF1KB8 MATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 MATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPR
              370       380       390       400       410       420

          420       430       440       450       460       470    
pF1KB8 LDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 LDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEA
              430       440       450       460       470       480

          480       490      
pF1KB8 SLRSSSMPDSGRPAFRVVDTEF
       ::::::::::::::::::::::
NP_148 SLRSSSMPDSGRPAFRVVDTEF
              490       500  

>>XP_016885058 (OMIM: 311550) PREDICTED: cyclin-dependen  (543 aa)
 initn: 3262 init1: 3262 opt: 3262  Z-score: 1349.9  bits: 259.4 E(85289): 1.9e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:48-543)

                                             10        20        30
pF1KB8                               MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQ
                                     ::::::::::::::::::::::::::::::
XP_016 SHYSRSSGYSRDLNTEIYPGGADLLVVAIAMDRMKKIKRQLSMTLRGGRGIDKTNGAPEQ
        20        30        40        50        60        70       

               40        50        60        70        80        90
pF1KB8 IGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSS
        80        90       100       110       120       130       

              100       110       120       130       140       150
pF1KB8 DEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLR
       140       150       160       170       180       190       

              160       170       180       190       200       210
pF1KB8 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR
       200       210       220       230       240       250       

              220       230       240       250       260       270
pF1KB8 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQL
       260       270       280       290       300       310       

              280       290       300       310       320       330
pF1KB8 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP
       320       330       340       350       360       370       

              340       350       360       370       380       390
pF1KB8 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL
       380       390       400       410       420       430       

              400       410       420       430       440       450
pF1KB8 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG
       440       450       460       470       480       490       

              460       470       480       490      
pF1KB8 ERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
       500       510       520       530       540   

>>NP_001163931 (OMIM: 311550) cyclin-dependent kinase 16  (570 aa)
 initn: 3262 init1: 3262 opt: 3262  Z-score: 1349.6  bits: 259.4 E(85289): 2e-68
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:75-570)

                                             10        20        30
pF1KB8                               MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQ
                                     ::::::::::::::::::::::::::::::
NP_001 CSGAFPLDPNNPSLGPLPSISHLNLRTQIAMDRMKKIKRQLSMTLRGGRGIDKTNGAPEQ
           50        60        70        80        90       100    

               40        50        60        70        80        90
pF1KB8 IGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSS
          110       120       130       140       150       160    

              100       110       120       130       140       150
pF1KB8 DEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLR
          170       180       190       200       210       220    

              160       170       180       190       200       210
pF1KB8 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR
          230       240       250       260       270       280    

              220       230       240       250       260       270
pF1KB8 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQL
          290       300       310       320       330       340    

              280       290       300       310       320       330
pF1KB8 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP
          350       360       370       380       390       400    

              340       350       360       370       380       390
pF1KB8 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL
          410       420       430       440       450       460    

              400       410       420       430       440       450
pF1KB8 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLG
          470       480       490       500       510       520    

              460       470       480       490      
pF1KB8 ERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
          530       540       550       560       570

>>XP_011542229 (OMIM: 311550) PREDICTED: cyclin-dependen  (497 aa)
 initn: 3180 init1: 3180 opt: 3180  Z-score: 1317.3  bits: 253.2 E(85289): 1.2e-66
Smith-Waterman score: 3180; 100.0% identity (100.0% similar) in 484 aa overlap (1-484:1-484)

               10        20        30        40        50        60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
              430       440       450       460       470       480

              490       
pF1KB8 MPDSGRPAFRVVDTEF 
       ::::             
XP_011 MPDSVAGGQHGRASLPH
              490       

>>XP_011542230 (OMIM: 311550) PREDICTED: cyclin-dependen  (497 aa)
 initn: 3180 init1: 3180 opt: 3180  Z-score: 1317.3  bits: 253.2 E(85289): 1.2e-66
Smith-Waterman score: 3180; 100.0% identity (100.0% similar) in 484 aa overlap (1-484:1-484)

               10        20        30        40        50        60
pF1KB8 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
              430       440       450       460       470       480

              490       
pF1KB8 MPDSGRPAFRVVDTEF 
       ::::             
XP_011 MPDSVAGGQHGRASLPH
              490       




496 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:09:52 2016 done: Fri Nov  4 10:09:54 2016
 Total Scan time:  8.650 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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