FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8166, 644 aa 1>>>pF1KB8166 644 - 644 aa - 644 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0772+/-0.000807; mu= 16.2799+/- 0.049 mean_var=93.2025+/-18.733, 0's: 0 Z-trim(109.5): 18 B-trim: 10 in 1/50 Lambda= 0.132850 statistics sampled from 10955 (10964) to 10955 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.337), width: 16 Scan time: 3.950 The best scores are: opt bits E(32554) CCDS7321.1 ECD gene_id:11319|Hs108|chr10 ( 644) 4315 837.4 0 CCDS44434.1 ECD gene_id:11319|Hs108|chr10 ( 677) 2579 504.7 1.6e-142 CCDS44433.1 ECD gene_id:11319|Hs108|chr10 ( 601) 2253 442.2 9.6e-124 >>CCDS7321.1 ECD gene_id:11319|Hs108|chr10 (644 aa) initn: 4315 init1: 4315 opt: 4315 Z-score: 4470.5 bits: 837.4 E(32554): 0 Smith-Waterman score: 4315; 100.0% identity (100.0% similar) in 644 aa overlap (1-644:1-644) 10 20 30 40 50 60 pF1KB8 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELPREPSEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 DQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELPREPSEAP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 ITFDADSFLNYFDKILGPRPNESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 ITFDADSFLNYFDKILGPRPNESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 NLKSYMAQMDQELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 NLKSYMAQMDQELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL 550 560 570 580 590 600 610 620 630 640 pF1KB8 VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN :::::::::::::::::::::::::::::::::::::::::::: CCDS73 VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN 610 620 630 640 >>CCDS44434.1 ECD gene_id:11319|Hs108|chr10 (677 aa) initn: 2558 init1: 2558 opt: 2579 Z-score: 2672.0 bits: 504.7 E(32554): 1.6e-142 Smith-Waterman score: 4239; 95.1% identity (95.1% similar) in 677 aa overlap (1-644:1-677) 10 20 30 40 50 60 pF1KB8 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL 310 320 330 340 350 360 370 380 pF1KB8 EMAENYFQLSVDWPE---------------------------------SSLAMSPGEEIL ::::::::::::::: :::::::::::: CCDS44 EMAENYFQLSVDWPERLEVQWRDPGLLQAPPPGFTPFICLSLLSTWDNSSLAMSPGEEIL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 TLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSPDQLDQLLQEAVGKKESESVSKEEKEQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSPDQLDQLLQEAVGKKESESVSKEEKEQN 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB8 YDLTEVSESMKAFISKVSTHKGAELPREPSEAPITFDADSFLNYFDKILGPRPNESDSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YDLTEVSESMKAFISKVSTHKGAELPREPSEAPITFDADSFLNYFDKILGPRPNESDSDD 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB8 LDDEDFECLDSDDDLDFETHEPGEEASLKGTLDNLKSYMAQMDQELAHTCISKSFTTRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LDDEDFECLDSDDDLDFETHEPGEEASLKGTLDNLKSYMAQMDQELAHTCISKSFTTRNQ 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB8 VEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNLVSNILESYSSQAGLAGPASNLLQSMGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNLVSNILESYSSQAGLAGPASNLLQSMGV 610 620 630 640 650 660 630 640 pF1KB8 QLPDNTDHRPTSKPTKN ::::::::::::::::: CCDS44 QLPDNTDHRPTSKPTKN 670 >>CCDS44433.1 ECD gene_id:11319|Hs108|chr10 (601 aa) initn: 2253 init1: 2253 opt: 2253 Z-score: 2335.1 bits: 442.2 E(32554): 9.6e-124 Smith-Waterman score: 3916; 93.3% identity (93.3% similar) in 644 aa overlap (1-644:1-601) 10 20 30 40 50 60 pF1KB8 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL ::::::::::::::::::::: CCDS44 IDLRACRVFKTFLPETRIMTS--------------------------------------- 250 260 310 320 330 340 350 360 pF1KB8 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ----AHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL 270 280 290 300 310 370 380 390 400 410 420 pF1KB8 EMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSP 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB8 DQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELPREPSEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELPREPSEAP 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB8 ITFDADSFLNYFDKILGPRPNESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ITFDADSFLNYFDKILGPRPNESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLD 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB8 NLKSYMAQMDQELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NLKSYMAQMDQELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL 500 510 520 530 540 550 610 620 630 640 pF1KB8 VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN :::::::::::::::::::::::::::::::::::::::::::: CCDS44 VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN 560 570 580 590 600 644 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:10:26 2016 done: Fri Nov 4 10:10:26 2016 Total Scan time: 3.950 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]