FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8166, 644 aa 1>>>pF1KB8166 644 - 644 aa - 644 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1230+/-0.00034; mu= 15.8669+/- 0.021 mean_var=98.8414+/-20.146, 0's: 0 Z-trim(117.1): 16 B-trim: 361 in 2/49 Lambda= 0.129004 statistics sampled from 28873 (28881) to 28873 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.339), width: 16 Scan time: 9.710 The best scores are: opt bits E(85289) NP_009196 (OMIM: 616464) protein ecdysoneless homo ( 644) 4315 813.8 0 NP_001129224 (OMIM: 616464) protein ecdysoneless h ( 677) 2579 490.7 7e-138 NP_001129225 (OMIM: 616464) protein ecdysoneless h ( 601) 2253 430.0 1.2e-119 >>NP_009196 (OMIM: 616464) protein ecdysoneless homolog (644 aa) initn: 4315 init1: 4315 opt: 4315 Z-score: 4342.9 bits: 813.8 E(85289): 0 Smith-Waterman score: 4315; 100.0% identity (100.0% similar) in 644 aa overlap (1-644:1-644) 10 20 30 40 50 60 pF1KB8 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELPREPSEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 DQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELPREPSEAP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 ITFDADSFLNYFDKILGPRPNESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 ITFDADSFLNYFDKILGPRPNESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 NLKSYMAQMDQELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NLKSYMAQMDQELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL 550 560 570 580 590 600 610 620 630 640 pF1KB8 VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN :::::::::::::::::::::::::::::::::::::::::::: NP_009 VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN 610 620 630 640 >>NP_001129224 (OMIM: 616464) protein ecdysoneless homol (677 aa) initn: 2558 init1: 2558 opt: 2579 Z-score: 2596.4 bits: 490.7 E(85289): 7e-138 Smith-Waterman score: 4239; 95.1% identity (95.1% similar) in 677 aa overlap (1-644:1-677) 10 20 30 40 50 60 pF1KB8 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL 310 320 330 340 350 360 370 380 pF1KB8 EMAENYFQLSVDWPE---------------------------------SSLAMSPGEEIL ::::::::::::::: :::::::::::: NP_001 EMAENYFQLSVDWPERLEVQWRDPGLLQAPPPGFTPFICLSLLSTWDNSSLAMSPGEEIL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 TLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSPDQLDQLLQEAVGKKESESVSKEEKEQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSPDQLDQLLQEAVGKKESESVSKEEKEQN 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB8 YDLTEVSESMKAFISKVSTHKGAELPREPSEAPITFDADSFLNYFDKILGPRPNESDSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDLTEVSESMKAFISKVSTHKGAELPREPSEAPITFDADSFLNYFDKILGPRPNESDSDD 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB8 LDDEDFECLDSDDDLDFETHEPGEEASLKGTLDNLKSYMAQMDQELAHTCISKSFTTRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDDEDFECLDSDDDLDFETHEPGEEASLKGTLDNLKSYMAQMDQELAHTCISKSFTTRNQ 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB8 VEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNLVSNILESYSSQAGLAGPASNLLQSMGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNLVSNILESYSSQAGLAGPASNLLQSMGV 610 620 630 640 650 660 630 640 pF1KB8 QLPDNTDHRPTSKPTKN ::::::::::::::::: NP_001 QLPDNTDHRPTSKPTKN 670 >>NP_001129225 (OMIM: 616464) protein ecdysoneless homol (601 aa) initn: 2253 init1: 2253 opt: 2253 Z-score: 2269.2 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 3916; 93.3% identity (93.3% similar) in 644 aa overlap (1-644:1-601) 10 20 30 40 50 60 pF1KB8 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPMLVPYIWQNQPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILASESIRAAVNRRIRGYPEKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IDLRACRVFKTFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL ::::::::::::::::::::: NP_001 IDLRACRVFKTFLPETRIMTS--------------------------------------- 250 260 310 320 330 340 350 360 pF1KB8 GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----AHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERL 270 280 290 300 310 370 380 390 400 410 420 pF1KB8 EMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSP 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB8 DQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELPREPSEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELPREPSEAP 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB8 ITFDADSFLNYFDKILGPRPNESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITFDADSFLNYFDKILGPRPNESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLD 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB8 NLKSYMAQMDQELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKSYMAQMDQELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL 500 510 520 530 540 550 610 620 630 640 pF1KB8 VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN :::::::::::::::::::::::::::::::::::::::::::: NP_001 VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN 560 570 580 590 600 644 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:10:27 2016 done: Fri Nov 4 10:10:28 2016 Total Scan time: 9.710 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]