FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8172, 140 aa 1>>>pF1KB8172 140 - 140 aa - 140 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3539+/-0.000805; mu= 11.9213+/- 0.049 mean_var=68.6687+/-13.566, 0's: 0 Z-trim(107.1): 10 B-trim: 7 in 1/50 Lambda= 0.154773 statistics sampled from 9363 (9370) to 9363 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.288), width: 16 Scan time: 1.710 The best scores are: opt bits E(32554) CCDS3634.1 SNCA gene_id:6622|Hs108|chr4 ( 140) 879 204.6 1.6e-53 CCDS43252.1 SNCA gene_id:6622|Hs108|chr4 ( 112) 612 144.9 1.2e-35 CCDS4406.1 SNCB gene_id:6620|Hs108|chr5 ( 134) 459 110.8 2.7e-25 CCDS7380.1 SNCG gene_id:6623|Hs108|chr10 ( 127) 388 94.9 1.5e-20 >>CCDS3634.1 SNCA gene_id:6622|Hs108|chr4 (140 aa) initn: 879 init1: 879 opt: 879 Z-score: 1074.1 bits: 204.6 E(32554): 1.6e-53 Smith-Waterman score: 879; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP 70 80 90 100 110 120 130 140 pF1KB8 DNEAYEMPSEEGYQDYEPEA :::::::::::::::::::: CCDS36 DNEAYEMPSEEGYQDYEPEA 130 140 >>CCDS43252.1 SNCA gene_id:6622|Hs108|chr4 (112 aa) initn: 612 init1: 612 opt: 612 Z-score: 753.4 bits: 144.9 E(32554): 1.2e-35 Smith-Waterman score: 618; 80.0% identity (80.0% similar) in 140 aa overlap (1-140:1-112) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP :::::::::::::::::::::::::::::::::::::::::: CCDS43 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGK------------------ 70 80 90 100 130 140 pF1KB8 DNEAYEMPSEEGYQDYEPEA :::::::::: CCDS43 ----------EGYQDYEPEA 110 >>CCDS4406.1 SNCB gene_id:6620|Hs108|chr5 (134 aa) initn: 602 init1: 383 opt: 459 Z-score: 567.6 bits: 110.8 E(32554): 2.7e-25 Smith-Waterman score: 496; 61.6% identity (79.5% similar) in 146 aa overlap (1-140:1-134) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK ::::::::: ::::::::::::::::.::: :::::::::::::.::::.:::.:::::: CCDS44 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLG---KNEE---GAPQEGILE ::....:::: .: ::.::::::.::.... : :: : .: ..: CCDS44 EQASHLGGAVFSG-----------AGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIE 70 80 90 100 120 130 140 pF1KB8 DMPVDPDNEAYEMPSEEGYQDYEPEA . ..:..:.:: : .: ::.::::: CCDS44 PL-MEPEGESYEDPPQEEYQEYEPEA 110 120 130 >>CCDS7380.1 SNCG gene_id:6623|Hs108|chr10 (127 aa) initn: 549 init1: 381 opt: 388 Z-score: 482.2 bits: 94.9 E(32554): 1.5e-20 Smith-Waterman score: 388; 62.7% identity (88.2% similar) in 110 aa overlap (1-110:1-107) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK :::: ::.: ::::::.:.:::::::.::: ::::::.:::.::::.::..:..:::::: CCDS73 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP ::.. :. :::..:..:: :::: : .::...: :.:..: . .:::. CCDS73 EQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDL---RPSAPQQEGEASKEKEE 70 80 90 100 110 130 140 pF1KB8 DNEAYEMPSEEGYQDYEPEA CCDS73 VAEEAQSGGD 120 140 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:14:02 2016 done: Fri Nov 4 10:14:03 2016 Total Scan time: 1.710 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]