FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8176, 245 aa
1>>>pF1KB8176 245 - 245 aa - 245 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7135+/-0.00102; mu= 12.0061+/- 0.062
mean_var=63.7954+/-12.587, 0's: 0 Z-trim(102.7): 25 B-trim: 0 in 0/50
Lambda= 0.160576
statistics sampled from 7036 (7049) to 7036 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.217), width: 16
Scan time: 1.450
The best scores are: opt bits E(32554)
CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 ( 245) 1565 371.4 3.1e-103
CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 ( 245) 1289 307.5 5.4e-84
CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 ( 246) 1287 307.0 7.5e-84
CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 ( 246) 1107 265.3 2.7e-71
CCDS288.1 SFN gene_id:2810|Hs108|chr1 ( 248) 1094 262.3 2.2e-70
CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 ( 247) 1091 261.6 3.5e-70
CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 ( 255) 999 240.3 9.4e-64
>>CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 (245 aa)
initn: 1565 init1: 1565 opt: 1565 Z-score: 1966.9 bits: 371.4 E(32554): 3.1e-103
Smith-Waterman score: 1565; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245)
10 20 30 40 50 60
pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS16 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA
190 200 210 220 230 240
pF1KB8 EGAEN
:::::
CCDS16 EGAEN
>>CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 (245 aa)
initn: 1289 init1: 1289 opt: 1289 Z-score: 1621.4 bits: 307.5 E(32554): 5.4e-84
Smith-Waterman score: 1289; 79.6% identity (94.3% similar) in 245 aa overlap (1-245:1-245)
10 20 30 40 50 60
pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR
:.:.::.::::::::::::::::.:::.:::::::::::::::::::::::::.:::.::
CCDS62 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK
:.:::::::. ..:: :. ..::::.:.:::.::. :: ::.:.:: ::.. ::::::::
CCDS62 VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE
:::::.::::::: :::.: .:.:: ::::::.::::::::::::::::::::::::::
CCDS62 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA
:::.:: ::.::::::::::::::::.:.::::::::::::::::::::::. :.: .:.
CCDS62 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG
190 200 210 220 230 240
pF1KB8 EGAEN
::.::
CCDS62 EGGEN
>>CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 (246 aa)
initn: 1286 init1: 1286 opt: 1287 Z-score: 1618.8 bits: 307.0 E(32554): 7.5e-84
Smith-Waterman score: 1287; 81.6% identity (94.3% similar) in 245 aa overlap (1-245:3-246)
10 20 30 40 50
pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSA
:.:.::.::::::::::::::::. :::::::: :::::::::::::::::::.:::.
CCDS13 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 WRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFY
:::::::::::. ..:: :. :.::::.:.::..::. :::::::::: :::.:::::::
CCDS13 WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 LKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFY
:::::::::::.::: ::... :..::: ::::::.::::::::::::::::::::::::
CCDS13 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 YEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECD
:::::.:: ::.::::::::::::::::::.:::::::::::::::::::::.. :.: :
CCDS13 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
190 200 210 220 230 240
240
pF1KB8 AAEGAEN
:.:: ::
CCDS13 AGEG-EN
>>CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 (246 aa)
initn: 968 init1: 647 opt: 1107 Z-score: 1393.5 bits: 265.3 E(32554): 2.7e-71
Smith-Waterman score: 1107; 71.4% identity (88.2% similar) in 245 aa overlap (2-242:3-245)
10 20 30 40 50
pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAW
.. .:.:.:.::::::::::::. :::::: . ::::.:::::::::::::.:::.:
CCDS13 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 RVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATN--PESK
:::::::::: : ..:::. .: ::::.:.::...:. :: ::::.:: : .. :::
CCDS13 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 VFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFS
::::::::::.::::::: :. ...... :..::.:::.:::..::::::::::::::::
CCDS13 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 VFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGE
:::::: : :: :: ::: :::.:::::::::::::::::::::::::::::::::. :
CCDS13 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE
190 200 210 220 230 240
240
pF1KB8 ECDAAEGAEN
: :.::
CCDS13 E--AGEGN
>>CCDS288.1 SFN gene_id:2810|Hs108|chr1 (248 aa)
initn: 1089 init1: 764 opt: 1094 Z-score: 1377.1 bits: 262.3 E(32554): 2.2e-70
Smith-Waterman score: 1094; 71.8% identity (90.8% similar) in 238 aa overlap (1-236:1-238)
10 20 30 40 50 60
pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR
::.. ::::::::::::::.:::. ::...:.: ::: ::::::::::::::::.:.:::
CCDS28 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 VISSIEQKTDT--SDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFY
:.::::::.. :..: ...::::::.::...: ::: :::..:: .: . ::.:::
CCDS28 VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 LKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFY
:::::::.::::::: :::.:. ::....:::::.::::::: ::.:::::::::::::.
CCDS28 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 YEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECD
::: :.:: : .::::.::::.:.: ::.::::::::::::::::::::::.:.::::
CCDS28 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGG
190 200 210 220 230 240
240
pF1KB8 AAEGAEN
CCDS28 EAPQEPQS
>>CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 (247 aa)
initn: 951 init1: 629 opt: 1091 Z-score: 1373.4 bits: 261.6 E(32554): 3.5e-70
Smith-Waterman score: 1091; 70.3% identity (87.4% similar) in 246 aa overlap (1-242:2-245)
10 20 30 40 50
pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAW
... .:.:::.::::::::::::. :: ::: . ::::::::::::::::::.:::.:
CCDS55 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 RVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANA--TNPESK
:::::::::: : ..::..... ::::.:.::...: :: :::.::: : :. :::
CCDS55 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 VFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFS
::::::::::.::::::: :. : ....:. ::.:: .:::..::::::::::::::.:
CCDS55 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 VFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGE
:::::: : :: :: :::::::.:::::::::::::::::::::::::::::::::. .
CCDS55 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQ--Q
190 200 210 220 230
240
pF1KB8 ECDAAEGAEN
. :..::
CCDS55 DDDGGEGNN
240
>>CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 (255 aa)
initn: 1000 init1: 727 opt: 999 Z-score: 1258.0 bits: 240.3 E(32554): 9.4e-64
Smith-Waterman score: 999; 65.3% identity (85.2% similar) in 236 aa overlap (2-235:3-238)
10 20 30 40 50
pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAW
.. .:. .:::::::::::.:. :: :. . .::. :::::::::::::.:.::..:
CCDS11 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 RVISSIEQKTDTS--DKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVF
:.::::::: ... . ::..:..::. ::.::. :: .:..:::.:: :.. :::::
CCDS11 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 YLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVF
: :::::: ::::: : :.:::.. .:: ::. : ::. :. ::::::::::::::::
CCDS11 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 YYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEEC
::::::.:. :: :::.:::.::::::::.:.:::::::::::::::::::::: :.
CCDS11 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGE
190 200 210 220 230 240
240
pF1KB8 DAAEGAEN
CCDS11 EQNKEALQDVEDENQ
250
245 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:16:39 2016 done: Fri Nov 4 10:16:39 2016
Total Scan time: 1.450 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]