FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8176, 245 aa 1>>>pF1KB8176 245 - 245 aa - 245 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7135+/-0.00102; mu= 12.0061+/- 0.062 mean_var=63.7954+/-12.587, 0's: 0 Z-trim(102.7): 25 B-trim: 0 in 0/50 Lambda= 0.160576 statistics sampled from 7036 (7049) to 7036 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.217), width: 16 Scan time: 1.450 The best scores are: opt bits E(32554) CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 ( 245) 1565 371.4 3.1e-103 CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 ( 245) 1289 307.5 5.4e-84 CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 ( 246) 1287 307.0 7.5e-84 CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 ( 246) 1107 265.3 2.7e-71 CCDS288.1 SFN gene_id:2810|Hs108|chr1 ( 248) 1094 262.3 2.2e-70 CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 ( 247) 1091 261.6 3.5e-70 CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 ( 255) 999 240.3 9.4e-64 >>CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 (245 aa) initn: 1565 init1: 1565 opt: 1565 Z-score: 1966.9 bits: 371.4 E(32554): 3.1e-103 Smith-Waterman score: 1565; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA 190 200 210 220 230 240 pF1KB8 EGAEN ::::: CCDS16 EGAEN >>CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 (245 aa) initn: 1289 init1: 1289 opt: 1289 Z-score: 1621.4 bits: 307.5 E(32554): 5.4e-84 Smith-Waterman score: 1289; 79.6% identity (94.3% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR :.:.::.::::::::::::::::.:::.:::::::::::::::::::::::::.:::.:: CCDS62 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK :.:::::::. ..:: :. ..::::.:.:::.::. :: ::.:.:: ::.. :::::::: CCDS62 VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE :::::.::::::: :::.: .:.:: ::::::.:::::::::::::::::::::::::: CCDS62 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA :::.:: ::.::::::::::::::::.:.::::::::::::::::::::::. :.: .:. CCDS62 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG 190 200 210 220 230 240 pF1KB8 EGAEN ::.:: CCDS62 EGGEN >>CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 (246 aa) initn: 1286 init1: 1286 opt: 1287 Z-score: 1618.8 bits: 307.0 E(32554): 7.5e-84 Smith-Waterman score: 1287; 81.6% identity (94.3% similar) in 245 aa overlap (1-245:3-246) 10 20 30 40 50 pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSA :.:.::.::::::::::::::::. :::::::: :::::::::::::::::::.:::. CCDS13 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 WRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFY :::::::::::. ..:: :. :.::::.:.::..::. :::::::::: :::.::::::: CCDS13 WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 LKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFY :::::::::::.::: ::... :..::: ::::::.:::::::::::::::::::::::: CCDS13 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 YEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECD :::::.:: ::.::::::::::::::::::.:::::::::::::::::::::.. :.: : CCDS13 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD 190 200 210 220 230 240 240 pF1KB8 AAEGAEN :.:: :: CCDS13 AGEG-EN >>CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 (246 aa) initn: 968 init1: 647 opt: 1107 Z-score: 1393.5 bits: 265.3 E(32554): 2.7e-71 Smith-Waterman score: 1107; 71.4% identity (88.2% similar) in 245 aa overlap (2-242:3-245) 10 20 30 40 50 pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAW .. .:.:.:.::::::::::::. :::::: . ::::.:::::::::::::.:::.: CCDS13 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 RVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATN--PESK :::::::::: : ..:::. .: ::::.:.::...:. :: ::::.:: : .. ::: CCDS13 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 VFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFS ::::::::::.::::::: :. ...... :..::.:::.:::..:::::::::::::::: CCDS13 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 VFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGE :::::: : :: :: ::: :::.:::::::::::::::::::::::::::::::::. : CCDS13 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE 190 200 210 220 230 240 240 pF1KB8 ECDAAEGAEN : :.:: CCDS13 E--AGEGN >>CCDS288.1 SFN gene_id:2810|Hs108|chr1 (248 aa) initn: 1089 init1: 764 opt: 1094 Z-score: 1377.1 bits: 262.3 E(32554): 2.2e-70 Smith-Waterman score: 1094; 71.8% identity (90.8% similar) in 238 aa overlap (1-236:1-238) 10 20 30 40 50 60 pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR ::.. ::::::::::::::.:::. ::...:.: ::: ::::::::::::::::.:.::: CCDS28 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 VISSIEQKTDT--SDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFY :.::::::.. :..: ...::::::.::...: ::: :::..:: .: . ::.::: CCDS28 VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 LKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFY :::::::.::::::: :::.:. ::....:::::.::::::: ::.:::::::::::::. CCDS28 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 YEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECD ::: :.:: : .::::.::::.:.: ::.::::::::::::::::::::::.:.:::: CCDS28 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGG 190 200 210 220 230 240 240 pF1KB8 AAEGAEN CCDS28 EAPQEPQS >>CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 (247 aa) initn: 951 init1: 629 opt: 1091 Z-score: 1373.4 bits: 261.6 E(32554): 3.5e-70 Smith-Waterman score: 1091; 70.3% identity (87.4% similar) in 246 aa overlap (1-242:2-245) 10 20 30 40 50 pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAW ... .:.:::.::::::::::::. :: ::: . ::::::::::::::::::.:::.: CCDS55 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 RVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANA--TNPESK :::::::::: : ..::..... ::::.:.::...: :: :::.::: : :. ::: CCDS55 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 VFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFS ::::::::::.::::::: :. : ....:. ::.:: .:::..::::::::::::::.: CCDS55 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 VFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGE :::::: : :: :: :::::::.:::::::::::::::::::::::::::::::::. . CCDS55 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQ--Q 190 200 210 220 230 240 pF1KB8 ECDAAEGAEN . :..:: CCDS55 DDDGGEGNN 240 >>CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 (255 aa) initn: 1000 init1: 727 opt: 999 Z-score: 1258.0 bits: 240.3 E(32554): 9.4e-64 Smith-Waterman score: 999; 65.3% identity (85.2% similar) in 236 aa overlap (2-235:3-238) 10 20 30 40 50 pF1KB8 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAW .. .:. .:::::::::::.:. :: :. . .::. :::::::::::::.:.::..: CCDS11 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 RVISSIEQKTDTS--DKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVF :.::::::: ... . ::..:..::. ::.::. :: .:..:::.:: :.. ::::: CCDS11 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 YLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVF : :::::: ::::: : :.:::.. .:: ::. : ::. :. :::::::::::::::: CCDS11 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 YYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEEC ::::::.:. :: :::.:::.::::::::.:.:::::::::::::::::::::: :. CCDS11 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGE 190 200 210 220 230 240 240 pF1KB8 DAAEGAEN CCDS11 EQNKEALQDVEDENQ 250 245 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:16:39 2016 done: Fri Nov 4 10:16:39 2016 Total Scan time: 1.450 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]