FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8179, 434 aa
1>>>pF1KB8179 434 - 434 aa - 434 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8905+/-0.000878; mu= 14.5515+/- 0.052
mean_var=76.3373+/-15.422, 0's: 0 Z-trim(106.9): 22 B-trim: 367 in 1/50
Lambda= 0.146793
statistics sampled from 9253 (9268) to 9253 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.285), width: 16
Scan time: 2.910
The best scores are: opt bits E(32554)
CCDS75382.1 RMND5B gene_id:64777|Hs108|chr5 ( 380) 2038 441.1 8.9e-124
CCDS4431.1 RMND5B gene_id:64777|Hs108|chr5 ( 393) 2038 441.1 9.2e-124
CCDS1991.1 RMND5A gene_id:64795|Hs108|chr2 ( 391) 1480 322.9 3.4e-88
CCDS77888.1 MAEA gene_id:10296|Hs108|chr4 ( 348) 283 69.4 6.3e-12
CCDS75090.1 MAEA gene_id:10296|Hs108|chr4 ( 395) 283 69.4 7e-12
CCDS33936.1 MAEA gene_id:10296|Hs108|chr4 ( 396) 283 69.4 7.1e-12
>>CCDS75382.1 RMND5B gene_id:64777|Hs108|chr5 (380 aa)
initn: 2038 init1: 2038 opt: 2038 Z-score: 2335.7 bits: 441.1 E(32554): 8.9e-124
Smith-Waterman score: 2258; 89.4% identity (89.4% similar) in 388 aa overlap (47-434:34-380)
20 30 40 50 60 70
pF1KB8 KFLTYGQHCERSLEELLHYVGQLRAELASAALQGTPLSATLSLVMSQCCRKIKDTVQKLA
::::::::::::::::::::::::::::::
CCDS75 CSLDLPGSSSPPSHLSLLRSWDHRRVPPCPALQGTPLSATLSLVMSQCCRKIKDTVQKLA
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB8 SDHKDIHSSVSRVGKAIDRVSTWPAPGVGWEHPEAGMYKDSKESQQECPHHQALSLLLRQ
:::::::::::::::::::
CCDS75 SDHKDIHSSVSRVGKAIDR-----------------------------------------
70 80
140 150 160 170 180 190
pF1KB8 NFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLSVAEELCQESTLNVDLDFKQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 NFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLSVAEELCQESTLNVDLDFKQP
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB8 FLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFKLHRLHFIRLLAGGPAKQLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 FLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFKLHRLHFIRLLAGGPAKQLEA
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB8 LSYARHFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDSSHWAEICETFTRDACSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LSYARHFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDSSHWAEICETFTRDACSL
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB8 LGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWNHKDELPIEIELGMKCWYHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWNHKDELPIEIELGMKCWYHSV
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB8 FACPILRQQTSDSNPPIKLICGHVISRDALNKLINGGKLKCPYCPMEQNPADGKRIIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 FACPILRQQTSDSNPPIKLICGHVISRDALNKLINGGKLKCPYCPMEQNPADGKRIIF
330 340 350 360 370 380
>>CCDS4431.1 RMND5B gene_id:64777|Hs108|chr5 (393 aa)
initn: 2038 init1: 2038 opt: 2038 Z-score: 2335.4 bits: 441.1 E(32554): 9.2e-124
Smith-Waterman score: 2565; 90.6% identity (90.6% similar) in 434 aa overlap (1-434:1-393)
10 20 30 40 50 60
pF1KB8 MEQCACVERELDKVLQKFLTYGQHCERSLEELLHYVGQLRAELASAALQGTPLSATLSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MEQCACVERELDKVLQKFLTYGQHCERSLEELLHYVGQLRAELASAALQGTPLSATLSLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 MSQCCRKIKDTVQKLASDHKDIHSSVSRVGKAIDRVSTWPAPGVGWEHPEAGMYKDSKES
:::::::::::::::::::::::::::::::::::
CCDS44 MSQCCRKIKDTVQKLASDHKDIHSSVSRVGKAIDR-------------------------
70 80 90
130 140 150 160 170 180
pF1KB8 QQECPHHQALSLLLRQNFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLSVAEE
::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ----------------NFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLSVAEE
100 110 120 130
190 200 210 220 230 240
pF1KB8 LCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFKLHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFKLHRL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB8 HFIRLLAGGPAKQLEALSYARHFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HFIRLLAGGPAKQLEALSYARHFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDSS
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB8 HWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWNHKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWNHKDE
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB8 LPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGGKLKCPYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGGKLKCPYC
320 330 340 350 360 370
430
pF1KB8 PMEQNPADGKRIIF
::::::::::::::
CCDS44 PMEQNPADGKRIIF
380 390
>>CCDS1991.1 RMND5A gene_id:64795|Hs108|chr2 (391 aa)
initn: 1859 init1: 1418 opt: 1480 Z-score: 1696.8 bits: 322.9 E(32554): 3.4e-88
Smith-Waterman score: 1816; 63.4% identity (81.8% similar) in 434 aa overlap (1-434:1-391)
10 20 30 40 50 60
pF1KB8 MEQCACVERELDKVLQKFLTYGQHCERSLEELLHYVGQLRAELASAALQGTPLSATLSLV
:.::. :::::.:::.:: ::: :::.::::. :.: :. :. .. : . ::.:::::
CCDS19 MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 MSQCCRKIKDTVQKLASDHKDIHSSVSRVGKAIDRVSTWPAPGVGWEHPEAGMYKDSKES
..:::..:::::::::::::::::::::::::::.
CCDS19 LTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDK-------------------------
70 80 90
130 140 150 160 170 180
pF1KB8 QQECPHHQALSLLLRQNFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLSVAEE
::::.: .: :. :.: ..:..:. ..:::...::::.::::
CCDS19 ----------------NFDSDISSVGIDGCWQA--DSQRLLNEVMVEHFFRQGMLDVAEE
100 110 120 130
190 200 210 220 230 240
pF1KB8 LCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFKLHRL
::::: :.:: . :.::.:::::::::. . : ::::::::.:. :. :::::::::::
CCDS19 LCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB8 HFIRLLAGGPAKQLEALSYARHFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDSS
.:: :: :: ..: :::.::..::::: ::..:::.:::::::: :.:.::: ::::..
CCDS19 YFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDAN
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB8 HWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWNHKDE
.::.::. ::::::.::::::::::::::..::::::.:.::::::::::::::::.:::
CCDS19 QWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDE
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB8 LPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGGKLKCPYC
::::..:: ::::::.::::::::::.:.:::.::.:::.::::::::..::.:::::::
CCDS19 LPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYC
320 330 340 350 360 370
430
pF1KB8 PMEQNPADGKRIIF
::::.:.:.:.:.:
CCDS19 PMEQSPGDAKQIFF
380 390
>>CCDS77888.1 MAEA gene_id:10296|Hs108|chr4 (348 aa)
initn: 264 init1: 97 opt: 283 Z-score: 327.6 bits: 69.4 E(32554): 6.3e-12
Smith-Waterman score: 283; 25.8% identity (58.5% similar) in 275 aa overlap (147-418:63-331)
120 130 140 150 160 170
pF1KB8 SKESQQECPHHQALSLLLRQNFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLS
:: : ... .. .:::: . :. .
CCDS77 LKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYN
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB8 VAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFK
.: .: ..: .. :: . :: ... :.:.... . : : ....:: ...: :::.
CCDS77 TAVKLARQSGIE-DLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFS
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB8 LHRLHFIRLLAGGPAKQLEALSYAR-HFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCH
:. .::.:. . :.:.:. .:: ::. . :.. :: :.. . :::
CCDS77 LRIQEFIELIRQN--KRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAF-PPDTHISPYKD
160 170 180 190 200
300 310 320 330 340 350
pF1KB8 LLDSSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVAL--PVLMNIKAVIEQRQCTG
::: ..: . . : : : :. .: ..... .: :. : .. . .. .:
CCDS77 LLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPV
210 220 230 240 250 260
360 370 380 390 400 410
pF1KB8 VWNHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGG
..: . .. .: .: ..: : . ...:::. : :.: . ..: .. .
CCDS77 CSRSLNKLAQPLPMA-HC-ANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDD
270 280 290 300 310 320
420 430
pF1KB8 KLKCPYCPMEQNPADGKRIIF
:. ::
CCDS77 KVVCPRTKEVFHFSQAEKVYIM
330 340
>>CCDS75090.1 MAEA gene_id:10296|Hs108|chr4 (395 aa)
initn: 264 init1: 97 opt: 283 Z-score: 326.7 bits: 69.4 E(32554): 7e-12
Smith-Waterman score: 283; 25.8% identity (58.5% similar) in 275 aa overlap (147-418:110-378)
120 130 140 150 160 170
pF1KB8 SKESQQECPHHQALSLLLRQNFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLS
:: : ... .. .:::: . :. .
CCDS75 LKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYN
80 90 100 110 120 130
180 190 200 210 220 230
pF1KB8 VAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFK
.: .: ..: .. :: . :: ... :.:.... . : : ....:: ...: :::.
CCDS75 TAVKLARQSGIE-DLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFS
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB8 LHRLHFIRLLAGGPAKQLEALSYAR-HFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCH
:. .::.:. . :.:.:. .:: ::. . :.. :: :.. . :::
CCDS75 LRIQEFIELIRQN--KRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAF-PPDTHISPYKD
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB8 LLDSSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVAL--PVLMNIKAVIEQRQCTG
::: ..: . . : : : :. .: ..... .: :. : .. . .. .:
CCDS75 LLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPV
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB8 VWNHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGG
..: . .. .: .: ..: : . ...:::. : :.: . ..: .. .
CCDS75 CSRSLNKLAQPLPMA-HC-ANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDD
320 330 340 350 360 370
420 430
pF1KB8 KLKCPYCPMEQNPADGKRIIF
:. ::
CCDS75 KVVCPRTKEVFHFSQAEKVYIM
380 390
>>CCDS33936.1 MAEA gene_id:10296|Hs108|chr4 (396 aa)
initn: 264 init1: 97 opt: 283 Z-score: 326.7 bits: 69.4 E(32554): 7.1e-12
Smith-Waterman score: 283; 25.8% identity (58.5% similar) in 275 aa overlap (147-418:111-379)
120 130 140 150 160 170
pF1KB8 SKESQQECPHHQALSLLLRQNFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGMLS
:: : ... .. .:::: . :. .
CCDS33 LKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYN
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB8 VAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFK
.: .: ..: .. :: . :: ... :.:.... . : : ....:: ...: :::.
CCDS33 TAVKLARQSGIE-DLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFS
150 160 170 180 190
240 250 260 270 280 290
pF1KB8 LHRLHFIRLLAGGPAKQLEALSYAR-HFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCH
:. .::.:. . :.:.:. .:: ::. . :.. :: :.. . :::
CCDS33 LRIQEFIELIRQN--KRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAF-PPDTHISPYKD
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB8 LLDSSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVAL--PVLMNIKAVIEQRQCTG
::: ..: . . : : : :. .: ..... .: :. : .. . .. .:
CCDS33 LLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPV
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB8 VWNHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGG
..: . .. .: .: ..: : . ...:::. : :.: . ..: .. .
CCDS33 CSRSLNKLAQPLPMA-HC-ANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDD
320 330 340 350 360 370
420 430
pF1KB8 KLKCPYCPMEQNPADGKRIIF
:. ::
CCDS33 KVVCPRTKEVFHFSQAEKVYIM
380 390
434 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:17:14 2016 done: Fri Nov 4 10:17:15 2016
Total Scan time: 2.910 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]