Result of FASTA (omim) for pF1KB8185
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8185, 461 aa
  1>>>pF1KB8185 461 - 461 aa - 461 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1963+/-0.000379; mu= 9.7769+/- 0.024
 mean_var=128.4008+/-25.988, 0's: 0 Z-trim(116.6): 37  B-trim: 951 in 1/59
 Lambda= 0.113185
 statistics sampled from 27894 (27931) to 27894 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.327), width:  16
 Scan time:  5.580

The best scores are:                                      opt bits E(85289)
NP_874368 (OMIM: 601409) histone acetyltransferase ( 461) 3130 522.4 9.7e-148
NP_001193762 (OMIM: 601409) histone acetyltransfer ( 494) 3107 518.7 1.4e-146
NP_006379 (OMIM: 601409) histone acetyltransferase ( 513) 2493 418.5 2.2e-116
XP_006718484 (OMIM: 601409) PREDICTED: histone ace ( 522) 2493 418.5 2.2e-116
NP_874369 (OMIM: 601409) histone acetyltransferase ( 546) 2493 418.5 2.3e-116
NP_115564 (OMIM: 609912) histone acetyltransferase ( 458) 1077 187.2   8e-47
XP_011544272 (OMIM: 609912) PREDICTED: histone ace ( 300) 1069 185.8 1.4e-46
XP_011544273 (OMIM: 609912) PREDICTED: histone ace ( 300) 1069 185.8 1.4e-46
XP_011522537 (OMIM: 609880) PREDICTED: histone ace ( 328) 1060 184.3 4.2e-46
NP_001186087 (OMIM: 609880) histone acetyltransfer ( 442) 1060 184.4 5.3e-46
NP_001186085 (OMIM: 609880) histone acetyltransfer ( 472) 1060 184.4 5.6e-46
NP_001186086 (OMIM: 609880) histone acetyltransfer ( 501) 1060 184.4 5.9e-46
NP_001186084 (OMIM: 609880) histone acetyltransfer ( 581) 1060 184.5 6.6e-46
NP_008998 (OMIM: 609880) histone acetyltransferase ( 611) 1060 184.5 6.9e-46
NP_892003 (OMIM: 609912) histone acetyltransferase ( 467) 1049 182.6 1.9e-45
NP_001292807 (OMIM: 601408,616268) histone acetylt ( 815) 1005 175.6 4.4e-43
XP_016869352 (OMIM: 601408,616268) PREDICTED: hist (2004) 1005 175.8 9.2e-43
NP_006757 (OMIM: 601408,616268) histone acetyltran (2004) 1005 175.8 9.2e-43
XP_016869353 (OMIM: 601408,616268) PREDICTED: hist (2004) 1005 175.8 9.2e-43
XP_011542961 (OMIM: 601408,616268) PREDICTED: hist (2041) 1005 175.8 9.3e-43
XP_011542959 (OMIM: 601408,616268) PREDICTED: hist (2048) 1005 175.8 9.4e-43
XP_011542958 (OMIM: 601408,616268) PREDICTED: hist (2048) 1005 175.8 9.4e-43
XP_011542960 (OMIM: 601408,616268) PREDICTED: hist (2048) 1005 175.8 9.4e-43
NP_001243398 (OMIM: 603736,605880,606170) histone  (1781)  957 168.0 1.9e-40
XP_016871496 (OMIM: 603736,605880,606170) PREDICTE (1781)  957 168.0 1.9e-40
XP_016871495 (OMIM: 603736,605880,606170) PREDICTE (1781)  957 168.0 1.9e-40
XP_016871497 (OMIM: 603736,605880,606170) PREDICTE (1781)  957 168.0 1.9e-40
XP_016871494 (OMIM: 603736,605880,606170) PREDICTE (1890)  947 166.4 6.2e-40
NP_001243397 (OMIM: 603736,605880,606170) histone  (1890)  947 166.4 6.2e-40
NP_036462 (OMIM: 603736,605880,606170) histone ace (2073)  947 166.4 6.7e-40
XP_016871492 (OMIM: 603736,605880,606170) PREDICTE (2073)  947 166.4 6.7e-40
XP_016871489 (OMIM: 603736,605880,606170) PREDICTE (2073)  947 166.4 6.7e-40
XP_016871491 (OMIM: 603736,605880,606170) PREDICTE (2073)  947 166.4 6.7e-40
XP_005269721 (OMIM: 603736,605880,606170) PREDICTE (2073)  947 166.4 6.7e-40
XP_016871490 (OMIM: 603736,605880,606170) PREDICTE (2073)  947 166.4 6.7e-40
XP_016871498 (OMIM: 603736,605880,606170) PREDICTE (1727)  306 61.7 1.9e-08
XP_016871493 (OMIM: 603736,605880,606170) PREDICTE (2019)  296 60.1 6.6e-08


>>NP_874368 (OMIM: 601409) histone acetyltransferase KAT  (461 aa)
 initn: 3130 init1: 3130 opt: 3130  Z-score: 2773.4  bits: 522.4 E(85289): 9.7e-148
Smith-Waterman score: 3130; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)

               10        20        30        40        50        60
pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVKRKVEVVSPATPVPSETAPASVFPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVKRKVEVVSPATPVPSETAPASVFPQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 NGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 NGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 ECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 IYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 IYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 GYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 SYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQY
              370       380       390       400       410       420

              430       440       450       460 
pF1KB8 ILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
       :::::::::::::::::::::::::::::::::::::::::
NP_874 ILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
              430       440       450       460 

>>NP_001193762 (OMIM: 601409) histone acetyltransferase   (494 aa)
 initn: 3107 init1: 3107 opt: 3107  Z-score: 2752.6  bits: 518.7 E(85289): 1.4e-146
Smith-Waterman score: 3107; 100.0% identity (100.0% similar) in 457 aa overlap (5-461:38-494)

                                         10        20        30    
pF1KB8                           MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSV
                                     ::::::::::::::::::::::::::::::
NP_001 VPGAGRREPGEVGRARGPPVADPGVALSPQGEIIEGCRLPVLRRNQDNEDEWPLAEILSV
        10        20        30        40        50        60       

           40        50        60        70        80        90    
pF1KB8 KDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPERE
        70        80        90       100       110       120       

          100       110       120       130       140       150    
pF1KB8 VKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGI
       130       140       150       160       170       180       

          160       170       180       190       200       210    
pF1KB8 PSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFC
       190       200       210       220       230       240       

          220       230       240       250       260       270    
pF1KB8 LKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDH
       250       260       270       280       290       300       

          280       290       300       310       320       330    
pF1KB8 KTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLI
       310       320       330       340       350       360       

          340       350       360       370       380       390    
pF1KB8 EFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISE
       370       380       390       400       410       420       

          400       410       420       430       440       450    
pF1KB8 ITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKD
       430       440       450       460       470       480       

          460 
pF1KB8 WSKRGKW
       :::::::
NP_001 WSKRGKW
       490    

>>NP_006379 (OMIM: 601409) histone acetyltransferase KAT  (513 aa)
 initn: 2487 init1: 2487 opt: 2493  Z-score: 2210.5  bits: 418.5 E(85289): 2.2e-116
Smith-Waterman score: 2882; 89.5% identity (89.5% similar) in 493 aa overlap (21-461:21-513)

               10        20        30        40        50        60
pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
                           ::::::::::::::::::::::::::::::::::::::::
NP_006 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
               10        20        30        40        50        60

               70        80        90                              
pF1KB8 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREV-------------------------
       :::::::::::::::::::::::::::::::::::                         
NP_006 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPK
               70        80        90       100       110       120

                                    100       110       120        
pF1KB8 ---------------------------KRKVEVVSPATPVPSETAPASVFPQNGAARRAV
                                  :::::::::::::::::::::::::::::::::
NP_006 EREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAV
              130       140       150       160       170       180

      130       140       150       160       170       180        
pF1KB8 AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH
              190       200       210       220       230       240

      190       200       210       220       230       240        
pF1KB8 RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS
              250       260       270       280       290       300

      250       260       270       280       290       300        
pF1KB8 FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE
              310       320       330       340       350       360

      310       320       330       340       350       360        
pF1KB8 STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ
              370       380       390       400       410       420

      370       380       390       400       410       420        
pF1KB8 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI
              430       440       450       460       470       480

      430       440       450       460 
pF1KB8 VDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
       :::::::::::::::::::::::::::::::::
NP_006 VDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
              490       500       510   

>>XP_006718484 (OMIM: 601409) PREDICTED: histone acetylt  (522 aa)
 initn: 2487 init1: 2487 opt: 2493  Z-score: 2210.4  bits: 418.5 E(85289): 2.2e-116
Smith-Waterman score: 2794; 87.6% identity (87.6% similar) in 493 aa overlap (30-461:30-522)

               10        20        30        40        50        60
pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
                                    :::::::::::::::::::::::::::::::
XP_006 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
               10        20        30        40        50        60

               70        80        90                              
pF1KB8 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREV-------------------------
       :::::::::::::::::::::::::::::::::::                         
XP_006 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVRKTLDLSLQPASAQASGKTLPIPVQ
               70        80        90       100       110       120

                                             100       110         
pF1KB8 ------------------------------------KRKVEVVSPATPVPSETAPASVFP
                                           ::::::::::::::::::::::::
XP_006 ITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFP
              130       140       150       160       170       180

     120       130       140       150       160       170         
pF1KB8 QNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKN
              190       200       210       220       230       240

     180       190       200       210       220       230         
pF1KB8 IECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGN
              250       260       270       280       290       300

     240       250       260       270       280       290         
pF1KB8 EIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHI
              310       320       330       340       350       360

     300       310       320       330       340       350         
pF1KB8 VGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGL
              370       380       390       400       410       420

     360       370       380       390       400       410         
pF1KB8 LSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQ
              430       440       450       460       470       480

     420       430       440       450       460 
pF1KB8 YILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
       ::::::::::::::::::::::::::::::::::::::::::
XP_006 YILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
              490       500       510       520  

>>NP_874369 (OMIM: 601409) histone acetyltransferase KAT  (546 aa)
 initn: 2487 init1: 2487 opt: 2493  Z-score: 2210.1  bits: 418.5 E(85289): 2.3e-116
Smith-Waterman score: 2882; 89.5% identity (89.5% similar) in 493 aa overlap (21-461:54-546)

                         10        20        30        40        50
pF1KB8           MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDF
                                     ::::::::::::::::::::::::::::::
NP_874 GPPVADPGVALSPQGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDF
            30        40        50        60        70        80   

               60        70        80        90                    
pF1KB8 NKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREV---------------
       :::::::::::::::::::::::::::::::::::::::::::::               
NP_874 NKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPV
            90       100       110       120       130       140   

                                              100       110        
pF1KB8 -------------------------------------KRKVEVVSPATPVPSETAPASVF
                                            :::::::::::::::::::::::
NP_874 QITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVF
           150       160       170       180       190       200   

      120       130       140       150       160       170        
pF1KB8 PQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 PQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMK
           210       220       230       240       250       260   

      180       190       200       210       220       230        
pF1KB8 NIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 NIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPG
           270       280       290       300       310       320   

      240       250       260       270       280       290        
pF1KB8 NEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 NEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFH
           330       340       350       360       370       380   

      300       310       320       330       340       350        
pF1KB8 IVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 IVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLG
           390       400       410       420       430       440   

      360       370       380       390       400       410        
pF1KB8 LLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_874 LLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKG
           450       460       470       480       490       500   

      420       430       440       450       460 
pF1KB8 QYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
       :::::::::::::::::::::::::::::::::::::::::::
NP_874 QYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
           510       520       530       540      

>>NP_115564 (OMIM: 609912) histone acetyltransferase KAT  (458 aa)
 initn: 1136 init1: 873 opt: 1077  Z-score: 961.6  bits: 187.2 E(85289): 8e-47
Smith-Waterman score: 1161; 43.4% identity (66.5% similar) in 454 aa overlap (3-452:56-447)

                                           10        20        30  
pF1KB8                             MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEIL
                                     :.::    :: :        .. :  ::..
NP_115 GENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYL-CRRP--------DSTWHSAEVI
          30        40        50        60                 70      

               40        50        60        70        80        90
pF1KB8 S--VKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGS
       .  :.:  ::. :::::. ::.:::::: ..:: : :     :.:   ...   .    .
NP_115 QSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKT---VKDAVQKNSEKYLSELAEQ
         80        90       100       110          120       130   

              100       110       120       130       140       150
pF1KB8 PEREVKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDS
       :::.. :.                                   .::: . ..  . .   
NP_115 PERKITRN-----------------------------------QKRKHDEINHVQKTYAE
           140                                          150        

              160       170       180       190       200       210
pF1KB8 SDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYL
        :  :.    :..:  .. :.  .:..: .. :..: ...  :::::.:..    : :.:
NP_115 MD--PT----TAAL--EKEHE-AITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWL
      160               170        180       190       200         

              220       230       240       250       260       270
pF1KB8 CEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKC
       ::.:::: .  :  . :: .:. :.:::.:::::..:: .:.::. .: : :::::::: 
NP_115 CEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKL
     210       220       230       240       250       260         

              280       290       300       310       320       330
pF1KB8 FLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYG
       ::::::::.:..::.::..:: : .: :::::::::::: .  :::::::::::::::::
NP_115 FLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYG
     270       280       290       300       310       320         

              340       350       360       370       380       390
pF1KB8 KLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITIN
       :.:: :::::::.:. .:.::::::::: :::::::: ..::::  .      :  ..:.
NP_115 KFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDF------RGTLSIK
     330       340       350       360       370             380   

              400       410       420       430        440         
pF1KB8 EISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER-AMLKRL-LRIDSKCL
       ..:..::: ..:.::::: ::...:.:::... ..  .:. : . :. :.  . .:: ::
NP_115 DLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCL
           390       400       410       420       430       440   

      450       460   
pF1KB8 HFTPKDWSKRGKW  
       ...:           
NP_115 KWAPPKHKQVKLSKK
           450        

>>XP_011544272 (OMIM: 609912) PREDICTED: histone acetylt  (300 aa)
 initn: 1012 init1: 873 opt: 1069  Z-score: 957.2  bits: 185.8 E(85289): 1.4e-46
Smith-Waterman score: 1069; 53.5% identity (79.5% similar) in 288 aa overlap (167-452:9-289)

        140       150       160       170       180       190      
pF1KB8 KSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFS
                                     .. :.  .:..: .. :..: ...  ::::
XP_011                       MDPTTAALEKEHE-AITKVKYVDKIHIGNYEIDAWYFS
                                     10         20        30       

        200       210       220       230       240       250      
pF1KB8 PYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRK
       :.:..    : :.:::.:::: .  :  . :: .:. :.:::.:::::..:: .:.::. 
XP_011 PFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKD
        40        50        60        70        80        90       

        260       270       280       290       300       310      
pF1KB8 NKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVA
       .: : :::::::: ::::::::.:..::.::..:: : .: :::::::::::: .  :::
XP_011 HKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVA
       100       110       120       130       140       150       

        320       330       340       350       360       370      
pF1KB8 CILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMG
       :::::::::::::::.:: :::::::.:. .:.::::::::: :::::::: ..::::  
XP_011 CILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRD
       160       170       180       190       200       210       

        380       390       400       410       420       430      
pF1KB8 LKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER-A
       .      :  ..:...:..::: ..:.::::: ::...:.:::... ..  .:. : . :
XP_011 F------RGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSA
             220       230       240       250       260       270 

         440        450       460   
pF1KB8 MLKRL-LRIDSKCLHFTPKDWSKRGKW  
       . :.  . .:: ::...:           
XP_011 QYKKPPITVDSVCLKWAPPKHKQVKLSKK
             280       290       300

>>XP_011544273 (OMIM: 609912) PREDICTED: histone acetylt  (300 aa)
 initn: 1012 init1: 873 opt: 1069  Z-score: 957.2  bits: 185.8 E(85289): 1.4e-46
Smith-Waterman score: 1069; 53.5% identity (79.5% similar) in 288 aa overlap (167-452:9-289)

        140       150       160       170       180       190      
pF1KB8 KSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFS
                                     .. :.  .:..: .. :..: ...  ::::
XP_011                       MDPTTAALEKEHE-AITKVKYVDKIHIGNYEIDAWYFS
                                     10         20        30       

        200       210       220       230       240       250      
pF1KB8 PYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRK
       :.:..    : :.:::.:::: .  :  . :: .:. :.:::.:::::..:: .:.::. 
XP_011 PFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKD
        40        50        60        70        80        90       

        260       270       280       290       300       310      
pF1KB8 NKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVA
       .: : :::::::: ::::::::.:..::.::..:: : .: :::::::::::: .  :::
XP_011 HKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVA
       100       110       120       130       140       150       

        320       330       340       350       360       370      
pF1KB8 CILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMG
       :::::::::::::::.:: :::::::.:. .:.::::::::: :::::::: ..::::  
XP_011 CILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRD
       160       170       180       190       200       210       

        380       390       400       410       420       430      
pF1KB8 LKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER-A
       .      :  ..:...:..::: ..:.::::: ::...:.:::... ..  .:. : . :
XP_011 F------RGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSA
             220       230       240       250       260       270 

         440        450       460   
pF1KB8 MLKRL-LRIDSKCLHFTPKDWSKRGKW  
       . :.  . .:: ::...:           
XP_011 QYKKPPITVDSVCLKWAPPKHKQVKLSKK
             280       290       300

>>XP_011522537 (OMIM: 609880) PREDICTED: histone acetylt  (328 aa)
 initn: 1087 init1: 920 opt: 1060  Z-score: 948.7  bits: 184.3 E(85289): 4.2e-46
Smith-Waterman score: 1060; 52.9% identity (77.8% similar) in 297 aa overlap (159-452:33-324)

      130       140       150       160       170       180        
pF1KB8 AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH
                                     : . .: . : . .:.   . :. : .::.
XP_011 HRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRY
             10        20        30        40        50        60  

      190       200       210       220       230       240        
pF1KB8 RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS
       .:  :: ::::.: . :  ::.::::::: .:   :.::..::  .::::.::::::.::
XP_011 ELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSIS
             70        80        90       100       110       120  

      250       260       270       280       290       300        
pF1KB8 FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE
        ::.::.::: : :::::::: ::::::::::..::::::::: :  : :..:::::::.
XP_011 VFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKN
            130       140       150       160       170       180  

      310       320       330       340       350       360        
pF1KB8 STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ
       :  .:::.::::.: :.:.::::.::.::: ::::: :.:.::.:::::::.::::::..
XP_011 SFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKE
            190       200       210       220       230       240  

      370       380       390       400       410       420        
pF1KB8 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI
       ..:. : .....     .:.:.:::. :...  :..:::: :....:.::....   .:.
XP_011 VLLRYLHNFQGK-----EISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDL
            250            260       270       280       290       

      430       440          450       460 
pF1KB8 VDGHERAMLKRL---LRIDSKCLHFTPKDWSKRGKW
       .:       ::      .: .::..::         
XP_011 IDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT     
       300       310       320             

>>NP_001186087 (OMIM: 609880) histone acetyltransferase   (442 aa)
 initn: 1065 init1: 920 opt: 1060  Z-score: 946.8  bits: 184.4 E(85289): 5.3e-46
Smith-Waterman score: 1060; 52.9% identity (77.8% similar) in 297 aa overlap (159-452:147-438)

      130       140       150       160       170       180        
pF1KB8 AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH
                                     : . .: . : . .:.   . :. : .::.
NP_001 HRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRY
        120       130       140       150       160       170      

      190       200       210       220       230       240        
pF1KB8 RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS
       .:  :: ::::.: . :  ::.::::::: .:   :.::..::  .::::.::::::.::
NP_001 ELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSIS
        180       190       200       210       220       230      

      250       260       270       280       290       300        
pF1KB8 FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE
        ::.::.::: : :::::::: ::::::::::..::::::::: :  : :..:::::::.
NP_001 VFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKN
        240       250       260       270       280       290      

      310       320       330       340       350       360        
pF1KB8 STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ
       :  .:::.::::.: :.:.::::.::.::: ::::: :.:.::.:::::::.::::::..
NP_001 SFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKE
        300       310       320       330       340       350      

      370       380       390       400       410       420        
pF1KB8 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI
       ..:. : .....     .:.:.:::. :...  :..:::: :....:.::....   .:.
NP_001 VLLRYLHNFQGK-----EISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDL
        360            370       380       390       400       410 

      430       440          450       460 
pF1KB8 VDGHERAMLKRL---LRIDSKCLHFTPKDWSKRGKW
       .:       ::      .: .::..::         
NP_001 IDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT     
             420       430       440       




461 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:18:52 2016 done: Fri Nov  4 10:18:53 2016
 Total Scan time:  5.580 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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