FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8185, 461 aa 1>>>pF1KB8185 461 - 461 aa - 461 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1963+/-0.000379; mu= 9.7769+/- 0.024 mean_var=128.4008+/-25.988, 0's: 0 Z-trim(116.6): 37 B-trim: 951 in 1/59 Lambda= 0.113185 statistics sampled from 27894 (27931) to 27894 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.327), width: 16 Scan time: 5.580 The best scores are: opt bits E(85289) NP_874368 (OMIM: 601409) histone acetyltransferase ( 461) 3130 522.4 9.7e-148 NP_001193762 (OMIM: 601409) histone acetyltransfer ( 494) 3107 518.7 1.4e-146 NP_006379 (OMIM: 601409) histone acetyltransferase ( 513) 2493 418.5 2.2e-116 XP_006718484 (OMIM: 601409) PREDICTED: histone ace ( 522) 2493 418.5 2.2e-116 NP_874369 (OMIM: 601409) histone acetyltransferase ( 546) 2493 418.5 2.3e-116 NP_115564 (OMIM: 609912) histone acetyltransferase ( 458) 1077 187.2 8e-47 XP_011544272 (OMIM: 609912) PREDICTED: histone ace ( 300) 1069 185.8 1.4e-46 XP_011544273 (OMIM: 609912) PREDICTED: histone ace ( 300) 1069 185.8 1.4e-46 XP_011522537 (OMIM: 609880) PREDICTED: histone ace ( 328) 1060 184.3 4.2e-46 NP_001186087 (OMIM: 609880) histone acetyltransfer ( 442) 1060 184.4 5.3e-46 NP_001186085 (OMIM: 609880) histone acetyltransfer ( 472) 1060 184.4 5.6e-46 NP_001186086 (OMIM: 609880) histone acetyltransfer ( 501) 1060 184.4 5.9e-46 NP_001186084 (OMIM: 609880) histone acetyltransfer ( 581) 1060 184.5 6.6e-46 NP_008998 (OMIM: 609880) histone acetyltransferase ( 611) 1060 184.5 6.9e-46 NP_892003 (OMIM: 609912) histone acetyltransferase ( 467) 1049 182.6 1.9e-45 NP_001292807 (OMIM: 601408,616268) histone acetylt ( 815) 1005 175.6 4.4e-43 XP_016869352 (OMIM: 601408,616268) PREDICTED: hist (2004) 1005 175.8 9.2e-43 NP_006757 (OMIM: 601408,616268) histone acetyltran (2004) 1005 175.8 9.2e-43 XP_016869353 (OMIM: 601408,616268) PREDICTED: hist (2004) 1005 175.8 9.2e-43 XP_011542961 (OMIM: 601408,616268) PREDICTED: hist (2041) 1005 175.8 9.3e-43 XP_011542959 (OMIM: 601408,616268) PREDICTED: hist (2048) 1005 175.8 9.4e-43 XP_011542958 (OMIM: 601408,616268) PREDICTED: hist (2048) 1005 175.8 9.4e-43 XP_011542960 (OMIM: 601408,616268) PREDICTED: hist (2048) 1005 175.8 9.4e-43 NP_001243398 (OMIM: 603736,605880,606170) histone (1781) 957 168.0 1.9e-40 XP_016871496 (OMIM: 603736,605880,606170) PREDICTE (1781) 957 168.0 1.9e-40 XP_016871495 (OMIM: 603736,605880,606170) PREDICTE (1781) 957 168.0 1.9e-40 XP_016871497 (OMIM: 603736,605880,606170) PREDICTE (1781) 957 168.0 1.9e-40 XP_016871494 (OMIM: 603736,605880,606170) PREDICTE (1890) 947 166.4 6.2e-40 NP_001243397 (OMIM: 603736,605880,606170) histone (1890) 947 166.4 6.2e-40 NP_036462 (OMIM: 603736,605880,606170) histone ace (2073) 947 166.4 6.7e-40 XP_016871492 (OMIM: 603736,605880,606170) PREDICTE (2073) 947 166.4 6.7e-40 XP_016871489 (OMIM: 603736,605880,606170) PREDICTE (2073) 947 166.4 6.7e-40 XP_016871491 (OMIM: 603736,605880,606170) PREDICTE (2073) 947 166.4 6.7e-40 XP_005269721 (OMIM: 603736,605880,606170) PREDICTE (2073) 947 166.4 6.7e-40 XP_016871490 (OMIM: 603736,605880,606170) PREDICTE (2073) 947 166.4 6.7e-40 XP_016871498 (OMIM: 603736,605880,606170) PREDICTE (1727) 306 61.7 1.9e-08 XP_016871493 (OMIM: 603736,605880,606170) PREDICTE (2019) 296 60.1 6.6e-08 >>NP_874368 (OMIM: 601409) histone acetyltransferase KAT (461 aa) initn: 3130 init1: 3130 opt: 3130 Z-score: 2773.4 bits: 522.4 E(85289): 9.7e-148 Smith-Waterman score: 3130; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461) 10 20 30 40 50 60 pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVKRKVEVVSPATPVPSETAPASVFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVKRKVEVVSPATPVPSETAPASVFPQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 NGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 ECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 IYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 GYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 SYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQY 370 380 390 400 410 420 430 440 450 460 pF1KB8 ILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW ::::::::::::::::::::::::::::::::::::::::: NP_874 ILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 430 440 450 460 >>NP_001193762 (OMIM: 601409) histone acetyltransferase (494 aa) initn: 3107 init1: 3107 opt: 3107 Z-score: 2752.6 bits: 518.7 E(85289): 1.4e-146 Smith-Waterman score: 3107; 100.0% identity (100.0% similar) in 457 aa overlap (5-461:38-494) 10 20 30 pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSV :::::::::::::::::::::::::::::: NP_001 VPGAGRREPGEVGRARGPPVADPGVALSPQGEIIEGCRLPVLRRNQDNEDEWPLAEILSV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 KDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPERE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 VKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 PSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFC 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 LKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDH 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 KTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLI 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 EFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISE 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB8 ITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKD 430 440 450 460 470 480 460 pF1KB8 WSKRGKW ::::::: NP_001 WSKRGKW 490 >>NP_006379 (OMIM: 601409) histone acetyltransferase KAT (513 aa) initn: 2487 init1: 2487 opt: 2493 Z-score: 2210.5 bits: 418.5 E(85289): 2.2e-116 Smith-Waterman score: 2882; 89.5% identity (89.5% similar) in 493 aa overlap (21-461:21-513) 10 20 30 40 50 60 pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH :::::::::::::::::::::::::::::::::::::::: NP_006 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH 10 20 30 40 50 60 70 80 90 pF1KB8 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREV------------------------- ::::::::::::::::::::::::::::::::::: NP_006 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPK 70 80 90 100 110 120 100 110 120 pF1KB8 ---------------------------KRKVEVVSPATPVPSETAPASVFPQNGAARRAV ::::::::::::::::::::::::::::::::: NP_006 EREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAV 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB8 AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB8 RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB8 FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB8 STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB8 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI 430 440 450 460 470 480 430 440 450 460 pF1KB8 VDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW ::::::::::::::::::::::::::::::::: NP_006 VDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 490 500 510 >>XP_006718484 (OMIM: 601409) PREDICTED: histone acetylt (522 aa) initn: 2487 init1: 2487 opt: 2493 Z-score: 2210.4 bits: 418.5 E(85289): 2.2e-116 Smith-Waterman score: 2794; 87.6% identity (87.6% similar) in 493 aa overlap (30-461:30-522) 10 20 30 40 50 60 pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH ::::::::::::::::::::::::::::::: XP_006 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH 10 20 30 40 50 60 70 80 90 pF1KB8 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREV------------------------- ::::::::::::::::::::::::::::::::::: XP_006 ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVRKTLDLSLQPASAQASGKTLPIPVQ 70 80 90 100 110 120 100 110 pF1KB8 ------------------------------------KRKVEVVSPATPVPSETAPASVFP :::::::::::::::::::::::: XP_006 ITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFP 130 140 150 160 170 180 120 130 140 150 160 170 pF1KB8 QNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKN 190 200 210 220 230 240 180 190 200 210 220 230 pF1KB8 IECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGN 250 260 270 280 290 300 240 250 260 270 280 290 pF1KB8 EIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHI 310 320 330 340 350 360 300 310 320 330 340 350 pF1KB8 VGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGL 370 380 390 400 410 420 360 370 380 390 400 410 pF1KB8 LSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQ 430 440 450 460 470 480 420 430 440 450 460 pF1KB8 YILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW :::::::::::::::::::::::::::::::::::::::::: XP_006 YILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 490 500 510 520 >>NP_874369 (OMIM: 601409) histone acetyltransferase KAT (546 aa) initn: 2487 init1: 2487 opt: 2493 Z-score: 2210.1 bits: 418.5 E(85289): 2.3e-116 Smith-Waterman score: 2882; 89.5% identity (89.5% similar) in 493 aa overlap (21-461:54-546) 10 20 30 40 50 pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDF :::::::::::::::::::::::::::::: NP_874 GPPVADPGVALSPQGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDF 30 40 50 60 70 80 60 70 80 90 pF1KB8 NKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREV--------------- ::::::::::::::::::::::::::::::::::::::::::::: NP_874 NKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPV 90 100 110 120 130 140 100 110 pF1KB8 -------------------------------------KRKVEVVSPATPVPSETAPASVF ::::::::::::::::::::::: NP_874 QITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVF 150 160 170 180 190 200 120 130 140 150 160 170 pF1KB8 PQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 PQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMK 210 220 230 240 250 260 180 190 200 210 220 230 pF1KB8 NIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 NIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPG 270 280 290 300 310 320 240 250 260 270 280 290 pF1KB8 NEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 NEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFH 330 340 350 360 370 380 300 310 320 330 340 350 pF1KB8 IVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 IVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLG 390 400 410 420 430 440 360 370 380 390 400 410 pF1KB8 LLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_874 LLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKG 450 460 470 480 490 500 420 430 440 450 460 pF1KB8 QYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW ::::::::::::::::::::::::::::::::::::::::::: NP_874 QYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 510 520 530 540 >>NP_115564 (OMIM: 609912) histone acetyltransferase KAT (458 aa) initn: 1136 init1: 873 opt: 1077 Z-score: 961.6 bits: 187.2 E(85289): 8e-47 Smith-Waterman score: 1161; 43.4% identity (66.5% similar) in 454 aa overlap (3-452:56-447) 10 20 30 pF1KB8 MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEIL :.:: :: : .. : ::.. NP_115 GENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYL-CRRP--------DSTWHSAEVI 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 S--VKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGS . :.: ::. :::::. ::.:::::: ..:: : : :.: ... . . NP_115 QSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKT---VKDAVQKNSEKYLSELAEQ 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 PEREVKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDS :::.. :. .::: . .. . . NP_115 PERKITRN-----------------------------------QKRKHDEINHVQKTYAE 140 150 160 170 180 190 200 210 pF1KB8 SDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYL : :. :..: .. :. .:..: .. :..: ... :::::.:.. : :.: NP_115 MD--PT----TAAL--EKEHE-AITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWL 160 170 180 190 200 220 230 240 250 260 270 pF1KB8 CEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKC ::.:::: . : . :: .:. :.:::.:::::..:: .:.::. .: : :::::::: NP_115 CEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKL 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB8 FLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYG ::::::::.:..::.::..:: : .: :::::::::::: . ::::::::::::::::: NP_115 FLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYG 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB8 KLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITIN :.:: :::::::.:. .:.::::::::: :::::::: ..:::: . : ..:. NP_115 KFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDF------RGTLSIK 330 340 350 360 370 380 400 410 420 430 440 pF1KB8 EISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER-AMLKRL-LRIDSKCL ..:..::: ..:.::::: ::...:.:::... .. .:. : . :. :. . .:: :: NP_115 DLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCL 390 400 410 420 430 440 450 460 pF1KB8 HFTPKDWSKRGKW ...: NP_115 KWAPPKHKQVKLSKK 450 >>XP_011544272 (OMIM: 609912) PREDICTED: histone acetylt (300 aa) initn: 1012 init1: 873 opt: 1069 Z-score: 957.2 bits: 185.8 E(85289): 1.4e-46 Smith-Waterman score: 1069; 53.5% identity (79.5% similar) in 288 aa overlap (167-452:9-289) 140 150 160 170 180 190 pF1KB8 KSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFS .. :. .:..: .. :..: ... :::: XP_011 MDPTTAALEKEHE-AITKVKYVDKIHIGNYEIDAWYFS 10 20 30 200 210 220 230 240 250 pF1KB8 PYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRK :.:.. : :.:::.:::: . : . :: .:. :.:::.:::::..:: .:.::. XP_011 PFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKD 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB8 NKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVA .: : :::::::: ::::::::.:..::.::..:: : .: :::::::::::: . ::: XP_011 HKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVA 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB8 CILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMG :::::::::::::::.:: :::::::.:. .:.::::::::: :::::::: ..:::: XP_011 CILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRD 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB8 LKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER-A . : ..:...:..::: ..:.::::: ::...:.:::... .. .:. : . : XP_011 F------RGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSA 220 230 240 250 260 270 440 450 460 pF1KB8 MLKRL-LRIDSKCLHFTPKDWSKRGKW . :. . .:: ::...: XP_011 QYKKPPITVDSVCLKWAPPKHKQVKLSKK 280 290 300 >>XP_011544273 (OMIM: 609912) PREDICTED: histone acetylt (300 aa) initn: 1012 init1: 873 opt: 1069 Z-score: 957.2 bits: 185.8 E(85289): 1.4e-46 Smith-Waterman score: 1069; 53.5% identity (79.5% similar) in 288 aa overlap (167-452:9-289) 140 150 160 170 180 190 pF1KB8 KSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFS .. :. .:..: .. :..: ... :::: XP_011 MDPTTAALEKEHE-AITKVKYVDKIHIGNYEIDAWYFS 10 20 30 200 210 220 230 240 250 pF1KB8 PYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRK :.:.. : :.:::.:::: . : . :: .:. :.:::.:::::..:: .:.::. XP_011 PFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKD 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB8 NKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVA .: : :::::::: ::::::::.:..::.::..:: : .: :::::::::::: . ::: XP_011 HKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVA 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB8 CILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMG :::::::::::::::.:: :::::::.:. .:.::::::::: :::::::: ..:::: XP_011 CILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRD 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB8 LKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHER-A . : ..:...:..::: ..:.::::: ::...:.:::... .. .:. : . : XP_011 F------RGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSA 220 230 240 250 260 270 440 450 460 pF1KB8 MLKRL-LRIDSKCLHFTPKDWSKRGKW . :. . .:: ::...: XP_011 QYKKPPITVDSVCLKWAPPKHKQVKLSKK 280 290 300 >>XP_011522537 (OMIM: 609880) PREDICTED: histone acetylt (328 aa) initn: 1087 init1: 920 opt: 1060 Z-score: 948.7 bits: 184.3 E(85289): 4.2e-46 Smith-Waterman score: 1060; 52.9% identity (77.8% similar) in 297 aa overlap (159-452:33-324) 130 140 150 160 170 180 pF1KB8 AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH : . .: . : . .:. . :. : .::. XP_011 HRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRY 10 20 30 40 50 60 190 200 210 220 230 240 pF1KB8 RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS .: :: ::::.: . : ::.::::::: .: :.::..:: .::::.::::::.:: XP_011 ELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSIS 70 80 90 100 110 120 250 260 270 280 290 300 pF1KB8 FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE ::.::.::: : :::::::: ::::::::::..::::::::: : : :..:::::::. XP_011 VFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKN 130 140 150 160 170 180 310 320 330 340 350 360 pF1KB8 STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ : .:::.::::.: :.:.::::.::.::: ::::: :.:.::.:::::::.::::::.. XP_011 SFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKE 190 200 210 220 230 240 370 380 390 400 410 420 pF1KB8 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI ..:. : ..... .:.:.:::. :... :..:::: :....:.::.... .:. XP_011 VLLRYLHNFQGK-----EISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDL 250 260 270 280 290 430 440 450 460 pF1KB8 VDGHERAMLKRL---LRIDSKCLHFTPKDWSKRGKW .: :: .: .::..:: XP_011 IDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT 300 310 320 >>NP_001186087 (OMIM: 609880) histone acetyltransferase (442 aa) initn: 1065 init1: 920 opt: 1060 Z-score: 946.8 bits: 184.4 E(85289): 5.3e-46 Smith-Waterman score: 1060; 52.9% identity (77.8% similar) in 297 aa overlap (159-452:147-438) 130 140 150 160 170 180 pF1KB8 AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH : . .: . : . .:. . :. : .::. NP_001 HRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS .: :: ::::.: . : ::.::::::: .: :.::..:: .::::.::::::.:: NP_001 ELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSIS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE ::.::.::: : :::::::: ::::::::::..::::::::: : : :..:::::::. NP_001 VFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKN 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ : .:::.::::.: :.:.::::.::.::: ::::: :.:.::.:::::::.::::::.. NP_001 SFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB8 TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI ..:. : ..... .:.:.:::. :... :..:::: :....:.::.... .:. NP_001 VLLRYLHNFQGK-----EISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDL 360 370 380 390 400 410 430 440 450 460 pF1KB8 VDGHERAMLKRL---LRIDSKCLHFTPKDWSKRGKW .: :: .: .::..:: NP_001 IDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT 420 430 440 461 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:18:52 2016 done: Fri Nov 4 10:18:53 2016 Total Scan time: 5.580 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]