FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8187, 452 aa 1>>>pF1KB8187 452 - 452 aa - 452 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1865+/-0.0015; mu= -7.2870+/- 0.086 mean_var=424.7496+/-94.291, 0's: 0 Z-trim(108.3): 355 B-trim: 0 in 0/49 Lambda= 0.062231 statistics sampled from 9743 (10122) to 9743 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.311), width: 16 Scan time: 2.850 The best scores are: opt bits E(32554) CCDS7768.1 ILK gene_id:3611|Hs108|chr11 ( 452) 3138 297.0 2.7e-80 CCDS60713.1 ILK gene_id:3611|Hs108|chr11 ( 318) 2201 212.6 4.6e-55 CCDS60712.1 ILK gene_id:3611|Hs108|chr11 ( 391) 1812 177.8 1.7e-44 >>CCDS7768.1 ILK gene_id:3611|Hs108|chr11 (452 aa) initn: 3138 init1: 3138 opt: 3138 Z-score: 1555.0 bits: 297.0 E(32554): 2.7e-80 Smith-Waterman score: 3138; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB8 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 370 380 390 400 410 420 430 440 450 pF1KB8 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::: CCDS77 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 430 440 450 >>CCDS60713.1 ILK gene_id:3611|Hs108|chr11 (318 aa) initn: 2201 init1: 2201 opt: 2201 Z-score: 1102.1 bits: 212.6 E(32554): 4.6e-55 Smith-Waterman score: 2201; 100.0% identity (100.0% similar) in 318 aa overlap (135-452:1-318) 110 120 130 140 150 160 pF1KB8 HYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPY :::::::::::::::::::::::::::::: CCDS60 MPVDKAKAPLRELLRERAEKMGQNLNRIPY 10 20 30 170 180 190 200 210 220 pF1KB8 KDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKV 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB8 RDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEG 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB8 TNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSF 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB8 QCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKV 220 230 240 250 260 270 410 420 430 440 450 pF1KB8 ALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 280 290 300 310 >>CCDS60712.1 ILK gene_id:3611|Hs108|chr11 (391 aa) initn: 2535 init1: 1723 opt: 1812 Z-score: 912.4 bits: 177.8 E(32554): 1.7e-44 Smith-Waterman score: 2429; 83.0% identity (83.8% similar) in 452 aa overlap (1-452:1-391) 10 20 30 40 50 60 pF1KB8 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS60 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAES-- 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG :: : .: .. ::: CCDS60 -----------------------------------GQR--RWARISTVFH--TRT----- 120 130 190 200 210 220 230 240 pF1KB8 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP ::: : : :::::::::::::::::::::::::::::::::: CCDS60 ----HSGRGPPAL-----------GPLWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP 140 150 160 170 250 260 270 280 290 300 pF1KB8 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD 180 190 200 210 220 230 310 320 330 340 350 360 pF1KB8 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA 240 250 260 270 280 290 370 380 390 400 410 420 pF1KB8 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 300 310 320 330 340 350 430 440 450 pF1KB8 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::: CCDS60 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 360 370 380 390 452 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:20:04 2016 done: Fri Nov 4 10:20:05 2016 Total Scan time: 2.850 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]