FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8187, 452 aa 1>>>pF1KB8187 452 - 452 aa - 452 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2351+/-0.000684; mu= -5.6671+/- 0.041 mean_var=747.5384+/-170.860, 0's: 0 Z-trim(115.8): 589 B-trim: 1240 in 1/50 Lambda= 0.046909 statistics sampled from 25931 (26575) to 25931 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.312), width: 16 Scan time: 6.190 The best scores are: opt bits E(85289) XP_005252961 (OMIM: 602366) PREDICTED: integrin-li ( 452) 3138 228.7 2.5e-59 XP_011518367 (OMIM: 602366) PREDICTED: integrin-li ( 452) 3138 228.7 2.5e-59 NP_001014795 (OMIM: 602366) integrin-linked protei ( 452) 3138 228.7 2.5e-59 NP_004508 (OMIM: 602366) integrin-linked protein k ( 452) 3138 228.7 2.5e-59 NP_001014794 (OMIM: 602366) integrin-linked protei ( 452) 3138 228.7 2.5e-59 XP_016873161 (OMIM: 602366) PREDICTED: integrin-li ( 401) 2770 203.7 7.5e-52 XP_005252962 (OMIM: 602366) PREDICTED: integrin-li ( 318) 2201 165.0 2.6e-40 NP_001265371 (OMIM: 602366) integrin-linked protei ( 318) 2201 165.0 2.6e-40 NP_001265370 (OMIM: 602366) integrin-linked protei ( 391) 1812 138.8 2.4e-32 NP_598407 (OMIM: 609479,616890) mitogen-activated ( 455) 371 41.4 0.006 XP_016859812 (OMIM: 609479,616890) PREDICTED: mito ( 455) 371 41.4 0.006 XP_016859813 (OMIM: 609479,616890) PREDICTED: mito ( 455) 371 41.4 0.006 NP_057737 (OMIM: 609479,616890) mitogen-activated ( 800) 371 41.8 0.0078 XP_005246697 (OMIM: 609479,616890) PREDICTED: mito ( 800) 371 41.8 0.0078 NP_663306 (OMIM: 157800,602614,617137) mitogen-act ( 491) 363 40.9 0.009 NP_663305 (OMIM: 157800,602614,617137) mitogen-act ( 518) 363 41.0 0.0093 NP_003179 (OMIM: 157800,602614,617137) mitogen-act ( 579) 363 41.1 0.0098 NP_663304 (OMIM: 157800,602614,617137) mitogen-act ( 606) 363 41.1 0.01 >>XP_005252961 (OMIM: 602366) PREDICTED: integrin-linked (452 aa) initn: 3138 init1: 3138 opt: 3138 Z-score: 1186.0 bits: 228.7 E(85289): 2.5e-59 Smith-Waterman score: 3138; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB8 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 370 380 390 400 410 420 430 440 450 pF1KB8 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::: XP_005 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 430 440 450 >>XP_011518367 (OMIM: 602366) PREDICTED: integrin-linked (452 aa) initn: 3138 init1: 3138 opt: 3138 Z-score: 1186.0 bits: 228.7 E(85289): 2.5e-59 Smith-Waterman score: 3138; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB8 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 370 380 390 400 410 420 430 440 450 pF1KB8 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::: XP_011 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 430 440 450 >>NP_001014795 (OMIM: 602366) integrin-linked protein ki (452 aa) initn: 3138 init1: 3138 opt: 3138 Z-score: 1186.0 bits: 228.7 E(85289): 2.5e-59 Smith-Waterman score: 3138; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB8 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 370 380 390 400 410 420 430 440 450 pF1KB8 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::: NP_001 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 430 440 450 >>NP_004508 (OMIM: 602366) integrin-linked protein kinas (452 aa) initn: 3138 init1: 3138 opt: 3138 Z-score: 1186.0 bits: 228.7 E(85289): 2.5e-59 Smith-Waterman score: 3138; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB8 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 370 380 390 400 410 420 430 440 450 pF1KB8 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::: NP_004 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 430 440 450 >>NP_001014794 (OMIM: 602366) integrin-linked protein ki (452 aa) initn: 3138 init1: 3138 opt: 3138 Z-score: 1186.0 bits: 228.7 E(85289): 2.5e-59 Smith-Waterman score: 3138; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB8 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 370 380 390 400 410 420 430 440 450 pF1KB8 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::: NP_001 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 430 440 450 >>XP_016873161 (OMIM: 602366) PREDICTED: integrin-linked (401 aa) initn: 2770 init1: 2770 opt: 2770 Z-score: 1051.9 bits: 203.7 E(85289): 7.5e-52 Smith-Waterman score: 2770; 100.0% identity (100.0% similar) in 401 aa overlap (52-452:1-401) 30 40 50 60 70 80 pF1KB8 NTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRD :::::::::::::::::::::::::::::: XP_016 MLIMRGARINVMNRGDDTPLHLAASHGHRD 10 20 30 90 100 110 120 130 140 pF1KB8 IVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAK 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB8 APLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNE 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB8 NHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPP 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB8 APHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALN 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB8 SRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVL 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB8 LWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDM 340 350 360 370 380 390 450 pF1KB8 IVPILEKMQDK ::::::::::: XP_016 IVPILEKMQDK 400 >>XP_005252962 (OMIM: 602366) PREDICTED: integrin-linked (318 aa) initn: 2201 init1: 2201 opt: 2201 Z-score: 844.6 bits: 165.0 E(85289): 2.6e-40 Smith-Waterman score: 2201; 100.0% identity (100.0% similar) in 318 aa overlap (135-452:1-318) 110 120 130 140 150 160 pF1KB8 HYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPY :::::::::::::::::::::::::::::: XP_005 MPVDKAKAPLRELLRERAEKMGQNLNRIPY 10 20 30 170 180 190 200 210 220 pF1KB8 KDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKV 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB8 RDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEG 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB8 TNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSF 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB8 QCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKV 220 230 240 250 260 270 410 420 430 440 450 pF1KB8 ALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 280 290 300 310 >>NP_001265371 (OMIM: 602366) integrin-linked protein ki (318 aa) initn: 2201 init1: 2201 opt: 2201 Z-score: 844.6 bits: 165.0 E(85289): 2.6e-40 Smith-Waterman score: 2201; 100.0% identity (100.0% similar) in 318 aa overlap (135-452:1-318) 110 120 130 140 150 160 pF1KB8 HYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPY :::::::::::::::::::::::::::::: NP_001 MPVDKAKAPLRELLRERAEKMGQNLNRIPY 10 20 30 170 180 190 200 210 220 pF1KB8 KDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKV 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB8 RDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEG 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB8 TNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSF 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB8 QCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKV 220 230 240 250 260 270 410 420 430 440 450 pF1KB8 ALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 280 290 300 310 >>NP_001265370 (OMIM: 602366) integrin-linked protein ki (391 aa) initn: 2535 init1: 1723 opt: 1812 Z-score: 701.6 bits: 138.8 E(85289): 2.4e-32 Smith-Waterman score: 2429; 83.0% identity (83.8% similar) in 452 aa overlap (1-452:1-391) 10 20 30 40 50 60 pF1KB8 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAES-- 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG :: : .: .. ::: NP_001 -----------------------------------GQR--RWARISTVFH--TRT----- 120 130 190 200 210 220 230 240 pF1KB8 TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP ::: : : :::::::::::::::::::::::::::::::::: NP_001 ----HSGRGPPAL-----------GPLWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP 140 150 160 170 250 260 270 280 290 300 pF1KB8 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD 180 190 200 210 220 230 310 320 330 340 350 360 pF1KB8 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA 240 250 260 270 280 290 370 380 390 400 410 420 pF1KB8 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 300 310 320 330 340 350 430 440 450 pF1KB8 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK :::::::::::::::::::::::::::::::: NP_001 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 360 370 380 390 >>NP_598407 (OMIM: 609479,616890) mitogen-activated prot (455 aa) initn: 299 init1: 177 opt: 371 Z-score: 173.9 bits: 41.4 E(85289): 0.006 Smith-Waterman score: 395; 28.4% identity (61.6% similar) in 268 aa overlap (188-451:11-265) 160 170 180 190 200 210 pF1KB8 NLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDI : : .:.:. . . . : .....: ..: NP_598 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDK 10 20 30 40 220 230 240 250 260 270 pF1KB8 VVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSL : : .: ...: : ..:: :.. :. :: . ..:.. ::: NP_598 EVAV--------KKLLKIEKEAEILSVLSHRNIIQFYGVILEPP--NYGIVTEYASLGSL 50 60 70 80 90 280 290 300 310 320 330 pF1KB8 YNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPL-IPRHALNSRSVMIDEDMTARI- :. .. . . .:... . .: :.:.:: .:: :. . .. :.::.:.: : . .: NP_598 YDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKIC 100 110 120 130 140 150 340 350 360 370 380 390 pF1KB8 SMADVKFSFQCPGRMYAPA--WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFA ... .: . . . :.:::..:. : . .. : .:..:.:::..:::::: NP_598 DFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVS---ETCDTYSYGVVLWEMLTREVPFK 160 170 180 190 200 400 410 420 430 440 450 pF1KB8 DLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK : ..... :. .. : ::: . .:.. : . : :::.: .:. :::.:.. NP_598 GLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT 210 220 230 240 250 260 NP_598 SLPDKCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSN 270 280 290 300 310 320 452 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:20:05 2016 done: Fri Nov 4 10:20:06 2016 Total Scan time: 6.190 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]