FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8191, 425 aa 1>>>pF1KB8191 425 - 425 aa - 425 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7010+/-0.000343; mu= 6.0670+/- 0.021 mean_var=138.2441+/-27.677, 0's: 0 Z-trim(118.5): 44 B-trim: 274 in 1/56 Lambda= 0.109081 statistics sampled from 31473 (31520) to 31473 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.37), width: 16 Scan time: 8.030 The best scores are: opt bits E(85289) NP_005893 (OMIM: 603109,613795) mothers against de ( 425) 2990 482.0 1.2e-135 NP_001129409 (OMIM: 601366) mothers against decape ( 437) 2642 427.2 3.9e-119 XP_016881235 (OMIM: 601366) PREDICTED: mothers aga ( 437) 2642 427.2 3.9e-119 NP_001138575 (OMIM: 603109,613795) mothers against ( 381) 2544 411.8 1.5e-114 XP_011519862 (OMIM: 603109,613795) PREDICTED: moth ( 376) 2533 410.0 5e-114 XP_011524287 (OMIM: 601366) PREDICTED: mothers aga ( 414) 2342 380.0 6.1e-105 XP_016881237 (OMIM: 601366) PREDICTED: mothers aga ( 414) 2342 380.0 6.1e-105 XP_016881236 (OMIM: 601366) PREDICTED: mothers aga ( 418) 2342 380.0 6.1e-105 XP_011524286 (OMIM: 601366) PREDICTED: mothers aga ( 425) 2342 380.0 6.2e-105 XP_006722514 (OMIM: 601366) PREDICTED: mothers aga ( 467) 2342 380.0 6.7e-105 NP_001003652 (OMIM: 601366) mothers against decape ( 467) 2342 380.0 6.7e-105 XP_005258316 (OMIM: 601366) PREDICTED: mothers aga ( 467) 2342 380.0 6.7e-105 NP_005892 (OMIM: 601366) mothers against decapenta ( 467) 2342 380.0 6.7e-105 XP_016881234 (OMIM: 601366) PREDICTED: mothers aga ( 467) 2342 380.0 6.7e-105 NP_001138574 (OMIM: 603109,613795) mothers against ( 320) 2261 367.2 3.4e-101 NP_005896 (OMIM: 603295,615342) mothers against de ( 430) 1893 309.3 1.2e-83 XP_011519861 (OMIM: 603109,613795) PREDICTED: moth ( 381) 1755 287.6 3.7e-77 NP_001138576 (OMIM: 603109,613795) mothers against ( 230) 1615 265.5 1e-70 XP_005266458 (OMIM: 603295,615342) PREDICTED: moth ( 442) 1604 263.9 5.9e-70 XP_016881239 (OMIM: 601366) PREDICTED: mothers aga ( 227) 1480 244.2 2.5e-64 NP_001001420 (OMIM: 603110) mothers against decape ( 465) 1218 203.1 1.2e-51 XP_016864959 (OMIM: 603110) PREDICTED: mothers aga ( 465) 1218 203.1 1.2e-51 NP_001001419 (OMIM: 603110) mothers against decape ( 465) 1218 203.1 1.2e-51 NP_005894 (OMIM: 603110) mothers against decapenta ( 465) 1218 203.1 1.2e-51 NP_001003688 (OMIM: 601595) mothers against decape ( 465) 1192 199.0 2e-50 NP_005891 (OMIM: 601595) mothers against decapenta ( 465) 1192 199.0 2e-50 XP_011530266 (OMIM: 601595) PREDICTED: mothers aga ( 465) 1192 199.0 2e-50 XP_005263049 (OMIM: 601595) PREDICTED: mothers aga ( 465) 1192 199.0 2e-50 XP_011530263 (OMIM: 601595) PREDICTED: mothers aga ( 465) 1192 199.0 2e-50 XP_006714280 (OMIM: 601595) PREDICTED: mothers aga ( 465) 1192 199.0 2e-50 XP_011530264 (OMIM: 601595) PREDICTED: mothers aga ( 465) 1192 199.0 2e-50 XP_011530265 (OMIM: 601595) PREDICTED: mothers aga ( 465) 1192 199.0 2e-50 NP_001120689 (OMIM: 603295,615342) mothers against ( 467) 1153 192.9 1.4e-48 XP_016881238 (OMIM: 601366) PREDICTED: mothers aga ( 263) 877 149.3 1.1e-35 XP_006719890 (OMIM: 603295,615342) PREDICTED: moth ( 479) 876 149.3 1.9e-35 XP_005266460 (OMIM: 603295,615342) PREDICTED: moth ( 393) 849 145.0 3.1e-34 XP_005266461 (OMIM: 603295,615342) PREDICTED: moth ( 356) 833 142.5 1.6e-33 NP_005350 (OMIM: 139210,174900,175050,260350,60099 ( 552) 472 85.8 3e-16 NP_005576 (OMIM: 602931,614823) mothers against de ( 496) 386 72.2 3.3e-12 XP_011519863 (OMIM: 602931,614823) PREDICTED: moth ( 235) 371 69.7 8.9e-12 NP_001177751 (OMIM: 602932,612229) mothers against ( 211) 313 60.5 4.6e-09 NP_001177752 (OMIM: 602932,612229) mothers against ( 238) 313 60.6 5.1e-09 >>NP_005893 (OMIM: 603109,613795) mothers against decape (425 aa) initn: 2990 init1: 2990 opt: 2990 Z-score: 2556.0 bits: 482.0 E(85289): 1.2e-135 Smith-Waterman score: 2990; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB8 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 370 380 390 400 410 420 pF1KB8 CSSVS ::::: NP_005 CSSVS >>NP_001129409 (OMIM: 601366) mothers against decapentap (437 aa) initn: 2600 init1: 1454 opt: 2642 Z-score: 2259.8 bits: 427.2 E(85289): 3.9e-119 Smith-Waterman score: 2748; 89.7% identity (96.1% similar) in 437 aa overlap (1-425:1-437) 10 20 30 40 50 pF1KB8 MSSILPFTPPIVKRLLGWKK----------GEQNGQEEKWCEKAVKSLVKKLKKTGQLDE ::::::::::.::::::::: ::::::::::::::::::::::::::.::: NP_001 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCE ::::::::: ::::.::::::::::::::::::::::::::::::::::::::.:.: :: NP_001 LEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGI .:::.::::::::::::::::::::::::::::::: .:.::::::.::::::::::::: NP_001 YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI 130 140 150 160 170 180 180 190 200 210 220 pF1KB8 EPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCE ::::: :::::::::.::::::::.:.:.:::.::: .:::. .::....:::::::: : NP_001 EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR :::::::.::::::::::::::::::.::::::::::::::::::::::::::.::.::: NP_001 PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 370 380 390 400 410 420 410 420 pF1KB8 KVLTQMGSPSIRCSSVS ::::::::::.::::.: NP_001 KVLTQMGSPSVRCSSMS 430 >>XP_016881235 (OMIM: 601366) PREDICTED: mothers against (437 aa) initn: 2600 init1: 1454 opt: 2642 Z-score: 2259.8 bits: 427.2 E(85289): 3.9e-119 Smith-Waterman score: 2748; 89.7% identity (96.1% similar) in 437 aa overlap (1-425:1-437) 10 20 30 40 50 pF1KB8 MSSILPFTPPIVKRLLGWKK----------GEQNGQEEKWCEKAVKSLVKKLKKTGQLDE ::::::::::.::::::::: ::::::::::::::::::::::::::.::: XP_016 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCE ::::::::: ::::.::::::::::::::::::::::::::::::::::::::.:.: :: XP_016 LEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGI .:::.::::::::::::::::::::::::::::::: .:.::::::.::::::::::::: XP_016 YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI 130 140 150 160 170 180 180 190 200 210 220 pF1KB8 EPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCE ::::: :::::::::.::::::::.:.:.:::.::: .:::. .::....:::::::: : XP_016 EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR :::::::.::::::::::::::::::.::::::::::::::::::::::::::.::.::: XP_016 PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 370 380 390 400 410 420 410 420 pF1KB8 KVLTQMGSPSIRCSSVS ::::::::::.::::.: XP_016 KVLTQMGSPSVRCSSMS 430 >>NP_001138575 (OMIM: 603109,613795) mothers against dec (381 aa) initn: 2540 init1: 2540 opt: 2544 Z-score: 2177.4 bits: 411.8 E(85289): 1.5e-114 Smith-Waterman score: 2544; 98.1% identity (98.6% similar) in 366 aa overlap (60-425:16-381) 30 40 50 60 70 80 pF1KB8 WCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYC :. : . ::::::::::::::::::::: NP_001 MSCLHPRQTWKGAALVHRKAWWMGRSLDGRLQVSHRKGLPHVIYC 10 20 30 40 90 100 110 120 130 140 pF1KB8 RLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAE 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB8 FPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSP 110 120 130 140 150 160 210 220 230 240 250 260 pF1KB8 NPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERF 170 180 190 200 210 220 270 280 290 300 310 320 pF1KB8 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPA 230 240 250 260 270 280 330 340 350 360 370 380 pF1KB8 TVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTV 290 300 310 320 330 340 390 400 410 420 pF1KB8 TSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS :::::::::::::::::::::::::::::::::::: NP_001 TSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 350 360 370 380 >>XP_011519862 (OMIM: 603109,613795) PREDICTED: mothers (376 aa) initn: 2533 init1: 2533 opt: 2533 Z-score: 2168.1 bits: 410.0 E(85289): 5e-114 Smith-Waterman score: 2533; 100.0% identity (100.0% similar) in 356 aa overlap (70-425:21-376) 40 50 60 70 80 90 pF1KB8 KKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHS :::::::::::::::::::::::::::::: XP_011 MWTFAPNCGQSVCPERGSTLSLDGRLQVSHRKGLPHVIYCRLWRWPDLHS 10 20 30 40 50 100 110 120 130 140 150 pF1KB8 HHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHS 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 IPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNL 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB8 DLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNR 180 190 200 210 220 230 280 290 300 310 320 330 pF1KB8 NAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN 240 250 260 270 280 290 340 350 360 370 380 390 pF1KB8 LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH 300 310 320 330 340 350 400 410 420 pF1KB8 LNGPLQWLDKVLTQMGSPSIRCSSVS :::::::::::::::::::::::::: XP_011 LNGPLQWLDKVLTQMGSPSIRCSSVS 360 370 >>XP_011524287 (OMIM: 601366) PREDICTED: mothers against (414 aa) initn: 2178 init1: 1454 opt: 2342 Z-score: 2005.0 bits: 380.0 E(85289): 6.1e-105 Smith-Waterman score: 2342; 91.4% identity (98.3% similar) in 359 aa overlap (69-425:56-414) 40 50 60 70 80 90 pF1KB8 VKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH :::::::::::::::::::::::::::::: XP_011 STCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB8 SHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSH :::::.:.: ::.:::.::::::::::::::::::::::::::::::: .:.::::::.: XP_011 SHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTH 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB8 SIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAH ::::::::::::::::: :::::::::.::::::::.:.:.:::.::: .:::. .::.. XP_011 SIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVN 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB8 NNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSN ..:::::::: ::::::::.::::::::::::::::::.::::::::::::::::::::: XP_011 HSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSN 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB8 VNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP :::::.::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB8 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 330 340 350 360 370 380 400 410 420 pF1KB8 ELHLNGPLQWLDKVLTQMGSPSIRCSSVS ::::::::::::::::::::::.::::.: XP_011 ELHLNGPLQWLDKVLTQMGSPSVRCSSMS 390 400 410 >>XP_016881237 (OMIM: 601366) PREDICTED: mothers against (414 aa) initn: 2178 init1: 1454 opt: 2342 Z-score: 2005.0 bits: 380.0 E(85289): 6.1e-105 Smith-Waterman score: 2342; 91.4% identity (98.3% similar) in 359 aa overlap (69-425:56-414) 40 50 60 70 80 90 pF1KB8 VKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH :::::::::::::::::::::::::::::: XP_016 STCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB8 SHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSH :::::.:.: ::.:::.::::::::::::::::::::::::::::::: .:.::::::.: XP_016 SHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTH 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB8 SIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAH ::::::::::::::::: :::::::::.::::::::.:.:.:::.::: .:::. .::.. XP_016 SIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVN 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB8 NNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSN ..:::::::: ::::::::.::::::::::::::::::.::::::::::::::::::::: XP_016 HSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSN 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB8 VNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP :::::.::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB8 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 330 340 350 360 370 380 400 410 420 pF1KB8 ELHLNGPLQWLDKVLTQMGSPSIRCSSVS ::::::::::::::::::::::.::::.: XP_016 ELHLNGPLQWLDKVLTQMGSPSVRCSSMS 390 400 410 >>XP_016881236 (OMIM: 601366) PREDICTED: mothers against (418 aa) initn: 2178 init1: 1454 opt: 2342 Z-score: 2005.0 bits: 380.0 E(85289): 6.1e-105 Smith-Waterman score: 2342; 91.4% identity (98.3% similar) in 359 aa overlap (69-425:60-418) 40 50 60 70 80 90 pF1KB8 VKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH :::::::::::::::::::::::::::::: XP_016 TTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB8 SHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSH :::::.:.: ::.:::.::::::::::::::::::::::::::::::: .:.::::::.: XP_016 SHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTH 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB8 SIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAH ::::::::::::::::: :::::::::.::::::::.:.:.:::.::: .:::. .::.. XP_016 SIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVN 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB8 NNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSN ..:::::::: ::::::::.::::::::::::::::::.::::::::::::::::::::: XP_016 HSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSN 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB8 VNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP :::::.::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB8 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 330 340 350 360 370 380 400 410 420 pF1KB8 ELHLNGPLQWLDKVLTQMGSPSIRCSSVS ::::::::::::::::::::::.::::.: XP_016 ELHLNGPLQWLDKVLTQMGSPSVRCSSMS 390 400 410 >>XP_011524286 (OMIM: 601366) PREDICTED: mothers against (425 aa) initn: 2178 init1: 1454 opt: 2342 Z-score: 2004.8 bits: 380.0 E(85289): 6.2e-105 Smith-Waterman score: 2342; 91.4% identity (98.3% similar) in 359 aa overlap (69-425:67-425) 40 50 60 70 80 90 pF1KB8 VKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH :::::::::::::::::::::::::::::: XP_011 STCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH 40 50 60 70 80 90 100 110 120 130 140 150 pF1KB8 SHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSH :::::.:.: ::.:::.::::::::::::::::::::::::::::::: .:.::::::.: XP_011 SHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTH 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB8 SIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAH ::::::::::::::::: :::::::::.::::::::.:.:.:::.::: .:::. .::.. XP_011 SIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVN 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB8 NNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSN ..:::::::: ::::::::.::::::::::::::::::.::::::::::::::::::::: XP_011 HSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSN 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB8 VNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP :::::.::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP 280 290 300 310 320 330 340 350 360 370 380 390 pF1KB8 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 340 350 360 370 380 390 400 410 420 pF1KB8 ELHLNGPLQWLDKVLTQMGSPSIRCSSVS ::::::::::::::::::::::.::::.: XP_011 ELHLNGPLQWLDKVLTQMGSPSVRCSSMS 400 410 420 >>XP_006722514 (OMIM: 601366) PREDICTED: mothers against (467 aa) initn: 2301 init1: 1454 opt: 2342 Z-score: 2004.2 bits: 380.0 E(85289): 6.7e-105 Smith-Waterman score: 2608; 83.6% identity (89.7% similar) in 457 aa overlap (11-425:11-467) 10 20 30 40 50 pF1KB8 MSSILPFTPPIVKRLLGWKK----------GEQNGQEEKWCEKAVKSLVKKLKKTGQLDE .::::::::: ::::::::::::::::::::::::::.::: XP_006 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 10 20 30 40 50 60 60 70 80 pF1KB8 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR ::::::::: ::::.::: :::::::::::: XP_006 LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB8 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV :::::::::::::::::::::::.:.: ::.:::.::::::::::::::::::::::::: XP_006 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 130 140 150 160 170 180 150 160 170 180 190 pF1KB8 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS :::::: .:.::::::.:::::::::::::::::: :::::::::.::::::::.:.:.: XP_006 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD ::.::: .:::. .::....:::::::: ::::::::.::::::::::::::::::.::: XP_006 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB8 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP :::::::::::::::::::::::.::.::::::::::::::::::::::::::::::::: XP_006 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 310 320 330 340 350 360 320 330 340 350 360 370 pF1KB8 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 370 380 390 400 410 420 380 390 400 410 420 pF1KB8 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS ::::::::::::::::::::::::::::::::::::::::.::::.: XP_006 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 430 440 450 460 425 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:22:47 2016 done: Fri Nov 4 10:22:48 2016 Total Scan time: 8.030 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]