FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8194, 547 aa 1>>>pF1KB8194 547 - 547 aa - 547 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6212+/-0.00104; mu= 16.8791+/- 0.063 mean_var=72.0684+/-14.633, 0's: 0 Z-trim(103.7): 16 B-trim: 48 in 1/52 Lambda= 0.151078 statistics sampled from 7515 (7521) to 7515 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.597), E-opt: 0.2 (0.231), width: 16 Scan time: 2.340 The best scores are: opt bits E(32554) CCDS6065.1 ELP3 gene_id:55140|Hs108|chr8 ( 547) 3672 810.1 0 CCDS75717.1 ELP3 gene_id:55140|Hs108|chr8 ( 533) 3580 790.0 0 CCDS75718.1 ELP3 gene_id:55140|Hs108|chr8 ( 475) 3216 710.7 9.9e-205 CCDS64860.1 ELP3 gene_id:55140|Hs108|chr8 ( 455) 3096 684.5 7.1e-197 CCDS64861.1 ELP3 gene_id:55140|Hs108|chr8 ( 428) 2795 618.9 3.8e-177 >>CCDS6065.1 ELP3 gene_id:55140|Hs108|chr8 (547 aa) initn: 3672 init1: 3672 opt: 3672 Z-score: 4325.2 bits: 810.1 E(32554): 0 Smith-Waterman score: 3672; 100.0% identity (100.0% similar) in 547 aa overlap (1-547:1-547) 10 20 30 40 50 60 pF1KB8 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP 490 500 510 520 530 540 pF1KB8 YMVKMLK ::::::: CCDS60 YMVKMLK >>CCDS75717.1 ELP3 gene_id:55140|Hs108|chr8 (533 aa) initn: 3580 init1: 3580 opt: 3580 Z-score: 4217.0 bits: 790.0 E(32554): 0 Smith-Waterman score: 3580; 100.0% identity (100.0% similar) in 533 aa overlap (15-547:1-533) 10 20 30 40 50 60 pF1KB8 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI :::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI 10 20 30 40 70 80 90 100 110 120 pF1KB8 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB8 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB8 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP 470 480 490 500 510 520 pF1KB8 YMVKMLK ::::::: CCDS75 YMVKMLK 530 >>CCDS75718.1 ELP3 gene_id:55140|Hs108|chr8 (475 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 3789.0 bits: 710.7 E(32554): 9.9e-205 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 475 aa overlap (73-547:1-475) 50 60 70 80 90 100 pF1KB8 TKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHI :::::::::::::::::::::::::::::: CCDS75 MPKLKAKPIRTASGIAVVAVMCKPHRCPHI 10 20 30 110 120 130 140 150 160 pF1KB8 SFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB8 DKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIET 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB8 RPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 RPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB8 AHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 AHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSP 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB8 SDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVR 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB8 TREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 TREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFR 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB8 FELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 FELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVIS 400 410 420 430 440 450 530 540 pF1KB8 GVGTRNYYRKIGYRLQGPYMVKMLK ::::::::::::::::::::::::: CCDS75 GVGTRNYYRKIGYRLQGPYMVKMLK 460 470 >>CCDS64860.1 ELP3 gene_id:55140|Hs108|chr8 (455 aa) initn: 3096 init1: 3096 opt: 3096 Z-score: 3648.0 bits: 684.5 E(32554): 7.1e-197 Smith-Waterman score: 3096; 100.0% identity (100.0% similar) in 455 aa overlap (93-547:1-455) 70 80 90 100 110 120 pF1KB8 AVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEY :::::::::::::::::::::::::::::: CCDS64 MCKPHRCPHISFTGNICVYCPGGPDSDFEY 10 20 30 130 140 150 160 170 180 pF1KB8 STQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 STQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYR 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB8 DYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 DYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTR 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB8 LEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 LEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFT 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB8 EFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 EFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRV 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB8 YRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 YRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVEL 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB8 VRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 VRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGSVV 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB8 PVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 PVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYM 400 410 420 430 440 450 pF1KB8 VKMLK ::::: CCDS64 VKMLK >>CCDS64861.1 ELP3 gene_id:55140|Hs108|chr8 (428 aa) initn: 2792 init1: 2792 opt: 2795 Z-score: 3293.8 bits: 618.9 E(32554): 3.8e-177 Smith-Waterman score: 2795; 98.8% identity (98.8% similar) in 424 aa overlap (125-547:5-428) 100 110 120 130 140 150 pF1KB8 KPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYE-PTSMRAIRARYDPFLQTRHRIE : : : :::::::::::::::::::::: CCDS64 MSTHQFYRKYMCPTSMRAIRARYDPFLQTRHRIE 10 20 30 160 170 180 190 200 210 pF1KB8 QLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 QLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLT 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB8 KCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 KCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHL 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB8 AKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 AKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWK 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB8 SGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 SGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKD 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB8 LGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 LGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB8 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEH 340 350 360 370 380 390 520 530 540 pF1KB8 GSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK :::::::::::::::::::::::::::::::::: CCDS64 GSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK 400 410 420 547 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:25:17 2016 done: Fri Nov 4 10:25:17 2016 Total Scan time: 2.340 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]