FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8194, 547 aa 1>>>pF1KB8194 547 - 547 aa - 547 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9957+/-0.00041; mu= 20.8649+/- 0.026 mean_var=71.6756+/-14.591, 0's: 0 Z-trim(110.3): 12 B-trim: 0 in 0/54 Lambda= 0.151492 statistics sampled from 18610 (18619) to 18610 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.579), E-opt: 0.2 (0.218), width: 16 Scan time: 7.580 The best scores are: opt bits E(85289) NP_060561 (OMIM: 612722) elongator complex protein ( 547) 3672 812.3 0 NP_001271151 (OMIM: 612722) elongator complex prot ( 533) 3580 792.2 0 XP_016869093 (OMIM: 612722) PREDICTED: elongator c ( 541) 3518 778.7 0 NP_001271149 (OMIM: 612722) elongator complex prot ( 475) 3216 712.6 6.8e-205 NP_001271155 (OMIM: 612722) elongator complex prot ( 455) 3096 686.4 5.1e-197 NP_001271154 (OMIM: 612722) elongator complex prot ( 428) 2795 620.6 3.1e-177 NP_001271153 (OMIM: 612722) elongator complex prot ( 428) 2795 620.6 3.1e-177 XP_006716417 (OMIM: 612722) PREDICTED: elongator c ( 428) 2795 620.6 3.1e-177 >>NP_060561 (OMIM: 612722) elongator complex protein 3 i (547 aa) initn: 3672 init1: 3672 opt: 3672 Z-score: 4337.3 bits: 812.3 E(85289): 0 Smith-Waterman score: 3672; 100.0% identity (100.0% similar) in 547 aa overlap (1-547:1-547) 10 20 30 40 50 60 pF1KB8 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP 490 500 510 520 530 540 pF1KB8 YMVKMLK ::::::: NP_060 YMVKMLK >>NP_001271151 (OMIM: 612722) elongator complex protein (533 aa) initn: 3580 init1: 3580 opt: 3580 Z-score: 4228.8 bits: 792.2 E(85289): 0 Smith-Waterman score: 3580; 100.0% identity (100.0% similar) in 533 aa overlap (15-547:1-533) 10 20 30 40 50 60 pF1KB8 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI :::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI 10 20 30 40 70 80 90 100 110 120 pF1KB8 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB8 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB8 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP 470 480 490 500 510 520 pF1KB8 YMVKMLK ::::::: NP_001 YMVKMLK 530 >>XP_016869093 (OMIM: 612722) PREDICTED: elongator compl (541 aa) initn: 3514 init1: 3514 opt: 3518 Z-score: 4155.5 bits: 778.7 E(85289): 0 Smith-Waterman score: 3518; 98.1% identity (99.1% similar) in 535 aa overlap (1-535:1-535) 10 20 30 40 50 60 pF1KB8 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGP :::::::::::::::::::::::::::::::::::::::::::: . . .. :. XP_016 VVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVDVLGQRQRGGHHRSCS 490 500 510 520 530 540 pF1KB8 YMVKMLK XP_016 L >>NP_001271149 (OMIM: 612722) elongator complex protein (475 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 3799.5 bits: 712.6 E(85289): 6.8e-205 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 475 aa overlap (73-547:1-475) 50 60 70 80 90 100 pF1KB8 TKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHI :::::::::::::::::::::::::::::: NP_001 MPKLKAKPIRTASGIAVVAVMCKPHRCPHI 10 20 30 110 120 130 140 150 160 pF1KB8 SFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB8 DKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIET 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB8 RPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB8 AHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSP 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB8 SDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVR 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB8 TREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFR 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB8 FELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVIS 400 410 420 430 440 450 530 540 pF1KB8 GVGTRNYYRKIGYRLQGPYMVKMLK ::::::::::::::::::::::::: NP_001 GVGTRNYYRKIGYRLQGPYMVKMLK 460 470 >>NP_001271155 (OMIM: 612722) elongator complex protein (455 aa) initn: 3096 init1: 3096 opt: 3096 Z-score: 3658.0 bits: 686.4 E(85289): 5.1e-197 Smith-Waterman score: 3096; 100.0% identity (100.0% similar) in 455 aa overlap (93-547:1-455) 70 80 90 100 110 120 pF1KB8 AVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEY :::::::::::::::::::::::::::::: NP_001 MCKPHRCPHISFTGNICVYCPGGPDSDFEY 10 20 30 130 140 150 160 170 180 pF1KB8 STQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYR 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB8 DYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTR 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB8 LEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFT 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB8 EFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRV 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB8 YRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVEL 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB8 VRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGSVV 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB8 PVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYM 400 410 420 430 440 450 pF1KB8 VKMLK ::::: NP_001 VKMLK >>NP_001271154 (OMIM: 612722) elongator complex protein (428 aa) initn: 2792 init1: 2792 opt: 2795 Z-score: 3302.9 bits: 620.6 E(85289): 3.1e-177 Smith-Waterman score: 2795; 98.8% identity (98.8% similar) in 424 aa overlap (125-547:5-428) 100 110 120 130 140 150 pF1KB8 KPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYE-PTSMRAIRARYDPFLQTRHRIE : : : :::::::::::::::::::::: NP_001 MSTHQFYRKYMCPTSMRAIRARYDPFLQTRHRIE 10 20 30 160 170 180 190 200 210 pF1KB8 QLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLT 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB8 KCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHL 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB8 AKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWK 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB8 SGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKD 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB8 LGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB8 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEH 340 350 360 370 380 390 520 530 540 pF1KB8 GSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK :::::::::::::::::::::::::::::::::: NP_001 GSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK 400 410 420 >>NP_001271153 (OMIM: 612722) elongator complex protein (428 aa) initn: 2792 init1: 2792 opt: 2795 Z-score: 3302.9 bits: 620.6 E(85289): 3.1e-177 Smith-Waterman score: 2795; 98.8% identity (98.8% similar) in 424 aa overlap (125-547:5-428) 100 110 120 130 140 150 pF1KB8 KPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYE-PTSMRAIRARYDPFLQTRHRIE : : : :::::::::::::::::::::: NP_001 MSTHQFYRKYMCPTSMRAIRARYDPFLQTRHRIE 10 20 30 160 170 180 190 200 210 pF1KB8 QLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLT 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB8 KCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHL 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB8 AKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWK 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB8 SGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKD 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB8 LGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB8 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEH 340 350 360 370 380 390 520 530 540 pF1KB8 GSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK :::::::::::::::::::::::::::::::::: NP_001 GSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK 400 410 420 >>XP_006716417 (OMIM: 612722) PREDICTED: elongator compl (428 aa) initn: 2792 init1: 2792 opt: 2795 Z-score: 3302.9 bits: 620.6 E(85289): 3.1e-177 Smith-Waterman score: 2795; 98.8% identity (98.8% similar) in 424 aa overlap (125-547:5-428) 100 110 120 130 140 150 pF1KB8 KPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYE-PTSMRAIRARYDPFLQTRHRIE : : : :::::::::::::::::::::: XP_006 MSTHQFYRKYMCPTSMRAIRARYDPFLQTRHRIE 10 20 30 160 170 180 190 200 210 pF1KB8 QLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLT 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB8 KCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHL 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB8 AKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWK 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB8 SGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKD 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB8 LGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRL 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB8 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEH 340 350 360 370 380 390 520 530 540 pF1KB8 GSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK :::::::::::::::::::::::::::::::::: XP_006 GSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK 400 410 420 547 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:25:17 2016 done: Fri Nov 4 10:25:18 2016 Total Scan time: 7.580 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]