FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8195, 313 aa 1>>>pF1KB8195 313 - 313 aa - 313 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4792+/-0.00031; mu= 11.4677+/- 0.020 mean_var=105.9370+/-21.636, 0's: 0 Z-trim(118.3): 110 B-trim: 0 in 0/52 Lambda= 0.124609 statistics sampled from 31007 (31118) to 31007 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.365), width: 16 Scan time: 6.120 The best scores are: opt bits E(85289) XP_011526480 (OMIM: 603419) PREDICTED: small gluta ( 313) 2043 377.4 2.1e-104 NP_003012 (OMIM: 603419) small glutamine-rich tetr ( 313) 2043 377.4 2.1e-104 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 271 58.9 2.3e-08 NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 271 59.0 2.4e-08 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 271 59.0 2.6e-08 NP_006810 (OMIM: 605063) stress-induced-phosphopro ( 543) 256 56.3 1.6e-07 NP_001139547 (OMIM: 611477) RNA polymerase II-asso ( 631) 255 56.1 2.1e-07 NP_078880 (OMIM: 611477) RNA polymerase II-associa ( 665) 255 56.2 2.2e-07 NP_001269581 (OMIM: 605063) stress-induced-phospho ( 590) 254 56.0 2.3e-07 NP_001269582 (OMIM: 605063) stress-induced-phospho ( 519) 249 55.0 3.8e-07 XP_011515547 (OMIM: 603395,615505) PREDICTED: sper ( 487) 233 52.1 2.7e-06 NP_001139548 (OMIM: 611477) RNA polymerase II-asso ( 506) 231 51.8 3.5e-06 XP_011515543 (OMIM: 603395,615505) PREDICTED: sper ( 871) 233 52.3 4.2e-06 NP_003306 (OMIM: 601964) dnaJ homolog subfamily C ( 494) 223 50.3 9.3e-06 XP_011528324 (OMIM: 615098) PREDICTED: tetratricop (1390) 227 51.3 1.3e-05 XP_011528323 (OMIM: 615098) PREDICTED: tetratricop (1390) 227 51.3 1.3e-05 XP_011528322 (OMIM: 615098) PREDICTED: tetratricop (1400) 227 51.3 1.3e-05 XP_011528321 (OMIM: 615098) PREDICTED: tetratricop (1412) 227 51.3 1.3e-05 XP_016884162 (OMIM: 615098) PREDICTED: tetratricop (2451) 227 51.5 2.1e-05 XP_011528320 (OMIM: 615098) PREDICTED: tetratricop (2455) 227 51.5 2.1e-05 XP_005261462 (OMIM: 615098) PREDICTED: tetratricop (2473) 227 51.5 2.1e-05 NP_001138890 (OMIM: 615098) tetratricopeptide repe (2481) 227 51.5 2.1e-05 NP_001269429 (OMIM: 601963) tetratricopeptide repe ( 292) 213 48.4 2.1e-05 NP_003305 (OMIM: 601963) tetratricopeptide repeat ( 292) 213 48.4 2.1e-05 NP_060338 (OMIM: 610732) tetratricopeptide repeat ( 705) 216 49.2 3e-05 XP_016873439 (OMIM: 610732) PREDICTED: tetratricop ( 753) 216 49.2 3.1e-05 XP_016873438 (OMIM: 610732) PREDICTED: tetratricop ( 755) 216 49.2 3.1e-05 XP_016873437 (OMIM: 610732) PREDICTED: tetratricop ( 760) 216 49.2 3.2e-05 XP_016873436 (OMIM: 610732) PREDICTED: tetratricop ( 774) 216 49.2 3.2e-05 XP_016873433 (OMIM: 610732) PREDICTED: tetratricop ( 777) 216 49.2 3.2e-05 XP_016873432 (OMIM: 610732) PREDICTED: tetratricop ( 777) 216 49.2 3.2e-05 XP_016873434 (OMIM: 610732) PREDICTED: tetratricop ( 777) 216 49.2 3.2e-05 XP_005271661 (OMIM: 610732) PREDICTED: tetratricop ( 777) 216 49.2 3.2e-05 XP_016873435 (OMIM: 610732) PREDICTED: tetratricop ( 777) 216 49.2 3.2e-05 XP_011523471 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 211 48.1 3.8e-05 XP_011523469 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 211 48.1 3.8e-05 XP_011523470 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 211 48.1 3.8e-05 NP_001138238 (OMIM: 601964) dnaJ homolog subfamily ( 438) 211 48.1 3.8e-05 XP_016880483 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 211 48.1 3.8e-05 NP_005852 (OMIM: 607207,615768) E3 ubiquitin-prote ( 303) 208 47.5 4.1e-05 NP_570722 (OMIM: 127700,608706,615482) dyslexia su ( 420) 204 46.9 8.7e-05 NP_001305462 (OMIM: 610732) tetratricopeptide repe ( 711) 198 45.9 0.00028 XP_016869244 (OMIM: 603395,615505) PREDICTED: sper ( 814) 197 45.8 0.00036 XP_011515542 (OMIM: 603395,615505) PREDICTED: sper ( 875) 197 45.8 0.00038 XP_011515545 (OMIM: 603395,615505) PREDICTED: sper ( 926) 197 45.8 0.0004 XP_011515544 (OMIM: 603395,615505) PREDICTED: sper ( 926) 197 45.8 0.0004 NP_003105 (OMIM: 603395,615505) sperm-associated a ( 926) 197 45.8 0.0004 NP_757367 (OMIM: 603395,615505) sperm-associated a ( 926) 197 45.8 0.0004 XP_016869243 (OMIM: 603395,615505) PREDICTED: sper ( 961) 197 45.8 0.00041 NP_071393 (OMIM: 617076) FK506-binding protein-lik ( 349) 190 44.3 0.00043 >>XP_011526480 (OMIM: 603419) PREDICTED: small glutamine (313 aa) initn: 2043 init1: 2043 opt: 2043 Z-score: 1995.5 bits: 377.4 E(85289): 2.1e-104 Smith-Waterman score: 2043; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313) 10 20 30 40 50 60 pF1KB8 MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 YYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PQIQQLMSGMISGGNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQIQQLMSGMISGGNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIR 250 260 270 280 290 300 310 pF1KB8 SRTPSASNDDQQE ::::::::::::: XP_011 SRTPSASNDDQQE 310 >>NP_003012 (OMIM: 603419) small glutamine-rich tetratri (313 aa) initn: 2043 init1: 2043 opt: 2043 Z-score: 1995.5 bits: 377.4 E(85289): 2.1e-104 Smith-Waterman score: 2043; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313) 10 20 30 40 50 60 pF1KB8 MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 YYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PQIQQLMSGMISGGNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PQIQQLMSGMISGGNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIR 250 260 270 280 290 300 310 pF1KB8 SRTPSASNDDQQE ::::::::::::: NP_003 SRTPSASNDDQQE 310 >>NP_001191213 (OMIM: 600658) serine/threonine-protein p (477 aa) initn: 285 init1: 264 opt: 271 Z-score: 271.2 bits: 58.9 E(85289): 2.3e-08 Smith-Waterman score: 271; 36.1% identity (65.4% similar) in 133 aa overlap (64-196:2-133) 40 50 60 70 80 90 pF1KB8 VAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAER : : : : . . : ::.. .::. NP_001 MAMAEG-ERTECAEPPRDEPPADGALKRAEE 10 20 30 100 110 120 130 140 150 pF1KB8 LKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAIC :::..:. .:....: :..::..::::::.::.:. ::. :: . :. :. : ::: NP_001 LKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIE 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 IDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAPSPT .: : :.: : . . .:.: :. :. .... : .. : NP_001 LDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFER 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 GGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDLASL NP_001 AIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAY 160 170 180 190 200 210 >>NP_006238 (OMIM: 600658) serine/threonine-protein phos (499 aa) initn: 285 init1: 264 opt: 271 Z-score: 270.9 bits: 59.0 E(85289): 2.4e-08 Smith-Waterman score: 271; 36.1% identity (65.4% similar) in 133 aa overlap (64-196:2-133) 40 50 60 70 80 90 pF1KB8 VAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAER : : : : . . : ::.. .::. NP_006 MAMAEG-ERTECAEPPRDEPPADGALKRAEE 10 20 30 100 110 120 130 140 150 pF1KB8 LKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAIC :::..:. .:....: :..::..::::::.::.:. ::. :: . :. :. : ::: NP_006 LKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIE 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 IDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAPSPT .: : :.: : . . .:.: :. :. .... : .. : NP_006 LDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFER 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 GGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDLASL NP_006 AIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAY 160 170 180 190 200 210 >>XP_016882424 (OMIM: 600658) PREDICTED: serine/threonin (551 aa) initn: 264 init1: 264 opt: 271 Z-score: 270.3 bits: 59.0 E(85289): 2.6e-08 Smith-Waterman score: 271; 36.1% identity (65.4% similar) in 133 aa overlap (64-196:2-133) 40 50 60 70 80 90 pF1KB8 VAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAER : : : : . . : ::.. .::. XP_016 MAMAEG-ERTECAEPPRDEPPADGALKRAEE 10 20 30 100 110 120 130 140 150 pF1KB8 LKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAIC :::..:. .:....: :..::..::::::.::.:. ::. :: . :. :. : ::: XP_016 LKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIE 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 IDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAPSPT .: : :.: : . . .:.: :. :. .... : .. : XP_016 LDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFER 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 GGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDLASL XP_016 AIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAY 160 170 180 190 200 210 >>NP_006810 (OMIM: 605063) stress-induced-phosphoprotein (543 aa) initn: 278 init1: 248 opt: 256 Z-score: 255.8 bits: 56.3 E(85289): 1.6e-07 Smith-Waterman score: 256; 29.8% identity (62.4% similar) in 178 aa overlap (90-265:3-173) 60 70 80 90 100 110 pF1KB8 EIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIE ....:: .::. ..: :.. :.. :..::. NP_006 MEQVNELKEKGNKALSVGNIDDALQCYSEAIK 10 20 30 120 130 140 150 160 170 pF1KB8 LNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAV :.: : : . ::.:::.: :.: : .: ... . : ..:.:.: . :: ::. :: NP_006 LDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAK 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB8 AYYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMN :...:. . .: : .:. : .: : .. :.. .: .. . .:.. NP_006 RTYEEGLKHEANNPQLKEGLQNMEARLAERKF----MNPFNMPNLYQKLESDPRTRTLLS 100 110 120 130 140 240 250 260 270 280 290 pF1KB8 NPQIQQLMSGMISGGNNP--LGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRS .: ..:. . :.: ::: .: NP_006 DPTYRELIEQL---RNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPP 150 160 170 180 190 200 >-- initn: 231 init1: 231 opt: 249 Z-score: 249.0 bits: 55.0 E(85289): 3.9e-07 Smith-Waterman score: 249; 25.1% identity (64.3% similar) in 199 aa overlap (49-242:324-516) 20 30 40 50 60 70 pF1KB8 LRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSP ...:: .: :.... .... .. . NP_006 EDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRT-PDVLKKCQQAEKILKEQERL 300 310 320 330 340 350 80 90 100 110 120 130 pF1KB8 ARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKL : : : : : :..::: .. .. :.. : .::. :: .: . :::: :.:: NP_006 AYINP---DLALEE--KNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKL 360 370 380 390 400 140 150 160 170 180 190 pF1KB8 GNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSN .. :..:::. : ..:.. :.: : . :: ... ...:. :.:::.:: . . .. NP_006 LEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADG 410 420 430 440 450 460 200 210 220 230 240 250 pF1KB8 LK---IAELKLREAPSPTG--GVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISG . .:. . ...: . .... .. ....:.. . .....:: NP_006 YQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVI 470 480 490 500 510 520 260 270 280 290 300 310 pF1KB8 GNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIRSRTPSASNDDQQE NP_006 AQKIQKLMDVGLIAIR 530 540 >-- initn: 220 init1: 162 opt: 197 Z-score: 198.5 bits: 45.7 E(85289): 0.00026 Smith-Waterman score: 197; 32.0% identity (61.5% similar) in 122 aa overlap (72-182:202-323) 50 60 70 80 90 pF1KB8 AFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAER--LKTE-- : .. .. : ::: : .. :: . NP_006 DPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKEL 180 190 200 210 220 230 100 110 120 130 140 150 pF1KB8 GNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPA ::. .: ..:..:.. : :: ::.:.: .:. :.::.: . :.: . ::.:: . NP_006 GNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRE 240 250 260 270 280 290 160 170 180 190 200 210 pF1KB8 -------YSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAP .:::.:.: . . .:. .:. .: NP_006 NREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQER 300 310 320 330 340 350 220 230 240 250 260 270 pF1KB8 SPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDL NP_006 LAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQ 360 370 380 390 400 410 >>NP_001139547 (OMIM: 611477) RNA polymerase II-associat (631 aa) initn: 247 init1: 247 opt: 255 Z-score: 253.9 bits: 56.1 E(85289): 2.1e-07 Smith-Waterman score: 255; 33.1% identity (62.0% similar) in 163 aa overlap (52-212:96-256) 30 40 50 60 70 80 pF1KB8 GGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPART : . . : :. . .: . . :. : .. NP_001 KGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQE--SESEE 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB8 PPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNY . :: .: :: .::. .: ... :. : :... .: : : :::.:: .: .. NP_001 DGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKF 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB8 AGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNL-K : : .::. :. .. .:.:::.: : : .:.: :: :...:::.:.: ..: : NP_001 AVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRK 190 200 210 220 230 240 210 220 230 240 250 pF1KB8 IAE-LKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLG :.. : .: : NP_001 ISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIE 250 260 270 280 290 300 >-- initn: 233 init1: 212 opt: 236 Z-score: 235.4 bits: 52.7 E(85289): 2.2e-06 Smith-Waterman score: 236; 27.3% identity (58.0% similar) in 245 aa overlap (84-313:275-519) 60 70 80 90 100 110 pF1KB8 LPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHF ..... .: : .:: .: ..: :.. NP_001 SQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIEC 250 260 270 280 290 300 120 130 140 150 160 170 pF1KB8 YGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLN : ..: . :::. ::: :: :. .: : .:: .:: .: .::::..: : : . :. NP_001 YTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLG 310 320 330 340 350 360 180 190 200 210 220 pF1KB8 KHVEAVAYYKKALELDPDNETYKSNL-KIAELKLREAPSPTGG--VGSFDI------AGL : :: .. .: :.: :. ..: :: . :... : . ..:. :. NP_001 KLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQTIDVPDSTTAAAP 370 380 390 400 410 420 230 240 250 260 270 280 pF1KB8 LNNP-GFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDLASLI-QAG--QQF ::: .. .. . .. . .. .. .. ...: . .: .:: ::. :. NP_001 ENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDV 430 440 450 460 470 480 290 300 310 pF1KB8 AQQMQQQNPELIEQLRSQIRSRT--PSASNDDQQE :..... : ::: .:. . . : .:. : : NP_001 CQSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLY 490 500 510 520 530 540 NP_001 PKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKI 550 560 570 580 590 600 >>NP_078880 (OMIM: 611477) RNA polymerase II-associated (665 aa) initn: 247 init1: 247 opt: 255 Z-score: 253.6 bits: 56.2 E(85289): 2.2e-07 Smith-Waterman score: 255; 33.1% identity (62.0% similar) in 163 aa overlap (52-212:96-256) 30 40 50 60 70 80 pF1KB8 GGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPART : . . : :. . .: . . :. : .. NP_078 KGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQE--SESEE 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB8 PPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNY . :: .: :: .::. .: ... :. : :... .: : : :::.:: .: .. NP_078 DGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKF 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB8 AGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNL-K : : .::. :. .. .:.:::.: : : .:.: :: :...:::.:.: ..: : NP_078 AVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRK 190 200 210 220 230 240 210 220 230 240 250 pF1KB8 IAE-LKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLG :.. : .: : NP_078 ISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIE 250 260 270 280 290 300 >-- initn: 219 init1: 188 opt: 224 Z-score: 223.4 bits: 50.6 E(85289): 1e-05 Smith-Waterman score: 224; 27.0% identity (58.8% similar) in 211 aa overlap (84-288:275-483) 60 70 80 90 100 110 pF1KB8 LPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHF ..... .: : .:: .: ..: :.. NP_078 SQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIEC 250 260 270 280 290 300 120 130 140 150 160 170 pF1KB8 YGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLN : ..: . :::. ::: :: :. .: : .:: .:: .: .::::..: : : . :. NP_078 YTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLG 310 320 330 340 350 360 180 190 200 210 220 pF1KB8 KHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAPSPTG----GVGSFDIAGLLNNPG : :: .. .: :.: :. ..:. . .: : .. ... ..:: NP_078 KLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPP 370 380 390 400 410 420 230 240 250 260 270 280 pF1KB8 FMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQN--DLASLIQAGQQFAQQMQQQ . .. : . : . ...:. . : .: ...: .: .::..: : ... ..: NP_078 HPGSTKPL--KKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQ 430 440 450 460 470 480 290 300 310 pF1KB8 NPELIEQLRSQIRSRTPSASNDDQQE . NP_078 DDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATTVL 490 500 510 520 530 540 >>NP_001269581 (OMIM: 605063) stress-induced-phosphoprot (590 aa) initn: 276 init1: 246 opt: 254 Z-score: 253.3 bits: 56.0 E(85289): 2.3e-07 Smith-Waterman score: 254; 30.5% identity (61.5% similar) in 174 aa overlap (94-265:54-220) 70 80 90 100 110 120 pF1KB8 AAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPA :: .::. ..: :.. :.. :..::.:.: NP_001 RGYDWQCKRPIRVAEVRSSLHSWSLRWVNELKEKGNKALSVGNIDDALQCYSEAIKLDPH 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 NAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYK : : . ::.:::.: :.: : .: ... . : ..:.:.: . :: ::. :: :. NP_001 NHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYE 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 KALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQI ..:. . .: : .:. : .: : .. :.. .: .. . .:...: NP_001 EGLKHEANNPQLKEGLQNMEARLAERKF----MNPFNMPNLYQKLESDPRTRTLLSDPTY 150 160 170 180 190 250 260 270 280 290 300 pF1KB8 QQLMSGMISGGNNP--LGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIRS ..:. . :.: ::: .: NP_001 RELIEQL---RNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKET 200 210 220 230 240 250 >-- initn: 231 init1: 231 opt: 249 Z-score: 248.5 bits: 55.1 E(85289): 4.2e-07 Smith-Waterman score: 249; 25.1% identity (64.3% similar) in 199 aa overlap (49-242:371-563) 20 30 40 50 60 70 pF1KB8 LRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSP ...:: .: :.... .... .. . NP_001 EDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRT-PDVLKKCQQAEKILKEQERL 350 360 370 380 390 80 90 100 110 120 130 pF1KB8 ARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKL : : : : : :..::: .. .. :.. : .::. :: .: . :::: :.:: NP_001 AYINP---DLALEE--KNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKL 400 410 420 430 440 450 140 150 160 170 180 190 pF1KB8 GNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSN .. :..:::. : ..:.. :.: : . :: ... ...:. :.:::.:: . . .. NP_001 LEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADG 460 470 480 490 500 510 200 210 220 230 240 250 pF1KB8 LK---IAELKLREAPSPTG--GVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISG . .:. . ...: . .... .. ....:.. . .....:: NP_001 YQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVI 520 530 540 550 560 570 260 270 280 290 300 310 pF1KB8 GNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIRSRTPSASNDDQQE NP_001 AQKIQKLMDVGLIAIR 580 590 >-- initn: 220 init1: 162 opt: 197 Z-score: 198.0 bits: 45.7 E(85289): 0.00027 Smith-Waterman score: 197; 32.0% identity (61.5% similar) in 122 aa overlap (72-182:249-370) 50 60 70 80 90 pF1KB8 AFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAER--LKTE-- : .. .. : ::: : .. :: . NP_001 DPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKEL 220 230 240 250 260 270 100 110 120 130 140 150 pF1KB8 GNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPA ::. .: ..:..:.. : :: ::.:.: .:. :.::.: . :.: . ::.:: . NP_001 GNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRE 280 290 300 310 320 330 160 170 180 190 200 210 pF1KB8 -------YSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAP .:::.:.: . . .:. .:. .: NP_001 NREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQER 340 350 360 370 380 390 220 230 240 250 260 270 pF1KB8 SPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDL NP_001 LAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQ 400 410 420 430 440 450 >>NP_001269582 (OMIM: 605063) stress-induced-phosphoprot (519 aa) initn: 231 init1: 231 opt: 249 Z-score: 249.3 bits: 55.0 E(85289): 3.8e-07 Smith-Waterman score: 249; 25.1% identity (64.3% similar) in 199 aa overlap (49-242:300-492) 20 30 40 50 60 70 pF1KB8 LRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSP ...:: .: :.... .... .. . NP_001 EDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRT-PDVLKKCQQAEKILKEQERL 270 280 290 300 310 320 80 90 100 110 120 130 pF1KB8 ARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKL : : : : : :..::: .. .. :.. : .::. :: .: . :::: :.:: NP_001 AYINP---DLALEE--KNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKL 330 340 350 360 370 380 140 150 160 170 180 190 pF1KB8 GNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSN .. :..:::. : ..:.. :.: : . :: ... ...:. :.:::.:: . . .. NP_001 LEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADG 390 400 410 420 430 440 200 210 220 230 240 250 pF1KB8 LK---IAELKLREAPSPTG--GVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISG . .:. . ...: . .... .. ....:.. . .....:: NP_001 YQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVI 450 460 470 480 490 500 260 270 280 290 300 310 pF1KB8 GNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIRSRTPSASNDDQQE NP_001 AQKIQKLMDVGLIAIR 510 >-- initn: 304 init1: 162 opt: 197 Z-score: 198.8 bits: 45.7 E(85289): 0.00025 Smith-Waterman score: 197; 32.0% identity (61.5% similar) in 122 aa overlap (72-182:178-299) 50 60 70 80 90 pF1KB8 AFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAER--LKTE-- : .. .. : ::: : .. :: . NP_001 DPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKEL 150 160 170 180 190 200 100 110 120 130 140 150 pF1KB8 GNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPA ::. .: ..:..:.. : :: ::.:.: .:. :.::.: . :.: . ::.:: . NP_001 GNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRE 210 220 230 240 250 260 160 170 180 190 200 210 pF1KB8 -------YSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAP .:::.:.: . . .:. .:. .: NP_001 NREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQER 270 280 290 300 310 320 220 230 240 250 260 270 pF1KB8 SPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDL NP_001 LAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQ 330 340 350 360 370 380 313 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:25:58 2016 done: Fri Nov 4 10:25:59 2016 Total Scan time: 6.120 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]