FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8197, 165 aa 1>>>pF1KB8197 165 - 165 aa - 165 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8537+/-0.000352; mu= 14.2756+/- 0.022 mean_var=61.8441+/-12.549, 0's: 0 Z-trim(113.9): 81 B-trim: 0 in 0/55 Lambda= 0.163089 statistics sampled from 23369 (23463) to 23369 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.275), width: 16 Scan time: 4.400 The best scores are: opt bits E(85289) NP_066953 (OMIM: 123840) peptidyl-prolyl cis-trans ( 165) 1130 274.1 7.1e-74 NP_001137504 (OMIM: 608608) peptidyl-prolyl cis-tr ( 164) 954 232.7 2.1e-61 NP_005720 (OMIM: 604486) peptidyl-prolyl cis-trans ( 207) 893 218.4 5.2e-57 XP_016855541 (OMIM: 602435) PREDICTED: peptidyl-pr ( 217) 790 194.2 1.1e-49 NP_006103 (OMIM: 602435) peptidyl-prolyl cis-trans ( 301) 790 194.3 1.4e-49 XP_006710353 (OMIM: 602435) PREDICTED: peptidyl-pr ( 288) 774 190.5 1.8e-48 XP_011509880 (OMIM: 601181,608033) PREDICTED: E3 S (2281) 773 190.9 1.1e-47 XP_005264064 (OMIM: 601181,608033) PREDICTED: E3 S (2282) 773 190.9 1.1e-47 XP_011509878 (OMIM: 601181,608033) PREDICTED: E3 S (3199) 773 191.0 1.4e-47 NP_006258 (OMIM: 601181,608033) E3 SUMO-protein li (3224) 773 191.0 1.4e-47 XP_005264061 (OMIM: 601181,608033) PREDICTED: E3 S (3232) 773 191.0 1.4e-47 XP_005264062 (OMIM: 601181,608033) PREDICTED: E3 S (3232) 773 191.0 1.4e-47 XP_005264060 (OMIM: 601181,608033) PREDICTED: E3 S (3250) 773 191.0 1.4e-47 XP_011509877 (OMIM: 601181,608033) PREDICTED: E3 S (3257) 773 191.0 1.4e-47 XP_005264059 (OMIM: 601181,608033) PREDICTED: E3 S (3258) 773 191.0 1.4e-47 NP_001287910 (OMIM: 123840) peptidyl-prolyl cis-tr ( 105) 720 177.5 5.4e-45 NP_982281 (OMIM: 602435) peptidyl-prolyl cis-trans ( 296) 716 176.9 2.4e-44 XP_011538803 (OMIM: 602435) PREDICTED: peptidyl-pr ( 230) 713 176.1 3.2e-44 XP_016855540 (OMIM: 602435) PREDICTED: peptidyl-pr ( 314) 713 176.2 4e-44 NP_001181936 (OMIM: 602435) peptidyl-prolyl cis-tr ( 314) 713 176.2 4e-44 NP_000933 (OMIM: 123841,259440) peptidyl-prolyl ci ( 216) 699 172.8 2.9e-43 NP_001306222 (OMIM: 602435) peptidyl-prolyl cis-tr ( 283) 700 173.1 3.1e-43 XP_006710352 (OMIM: 602435) PREDICTED: peptidyl-pr ( 301) 697 172.4 5.3e-43 XP_005269436 (OMIM: 604486) PREDICTED: peptidyl-pr ( 201) 671 166.2 2.7e-41 NP_005029 (OMIM: 601753) peptidyl-prolyl cis-trans ( 370) 659 163.5 3.1e-40 NP_006338 (OMIM: 606095) peptidyl-prolyl cis-trans ( 177) 620 154.1 9.9e-38 XP_016855546 (OMIM: 606095) PREDICTED: peptidyl-pr ( 177) 620 154.1 9.9e-38 XP_005270419 (OMIM: 606095) PREDICTED: peptidyl-pr ( 177) 620 154.1 9.9e-38 NP_000934 (OMIM: 123842) peptidyl-prolyl cis-trans ( 212) 609 151.6 6.9e-37 XP_016860791 (OMIM: 606093) PREDICTED: peptidyl-pr ( 272) 558 139.7 3.4e-33 XP_005247023 (OMIM: 606093) PREDICTED: peptidyl-pr ( 754) 558 140.0 7.7e-33 XP_005247024 (OMIM: 606093) PREDICTED: peptidyl-pr ( 754) 558 140.0 7.7e-33 NP_004783 (OMIM: 606093) peptidyl-prolyl cis-trans ( 754) 558 140.0 7.7e-33 XP_016861963 (OMIM: 161565) PREDICTED: NK-tumor re (1435) 547 137.6 7.7e-32 XP_006713234 (OMIM: 161565) PREDICTED: NK-tumor re (1436) 547 137.6 7.7e-32 NP_005376 (OMIM: 161565) NK-tumor recognition prot (1462) 547 137.6 7.8e-32 XP_005265230 (OMIM: 161565) PREDICTED: NK-tumor re (1463) 547 137.6 7.8e-32 XP_016855548 (OMIM: 606095) PREDICTED: peptidyl-pr ( 134) 452 114.5 6.3e-26 NP_001317439 (OMIM: 606095) peptidyl-prolyl cis-tr ( 134) 452 114.5 6.3e-26 XP_016855547 (OMIM: 606095) PREDICTED: peptidyl-pr ( 134) 452 114.5 6.3e-26 NP_057143 (OMIM: 601301) peptidyl-prolyl cis-trans ( 166) 432 109.9 2e-24 XP_011509660 (OMIM: 615811) PREDICTED: peptidyl-pr ( 161) 392 100.5 1.3e-21 XP_016859844 (OMIM: 615811) PREDICTED: peptidyl-pr ( 161) 392 100.5 1.3e-21 NP_570981 (OMIM: 615811) peptidyl-prolyl cis-trans ( 161) 392 100.5 1.3e-21 XP_005246709 (OMIM: 615811) PREDICTED: peptidyl-pr ( 161) 392 100.5 1.3e-21 XP_016859845 (OMIM: 615811) PREDICTED: peptidyl-pr ( 161) 392 100.5 1.3e-21 XP_016884195 (OMIM: 607588) PREDICTED: peptidyl-pr ( 266) 367 94.7 1.1e-19 XP_016884194 (OMIM: 607588) PREDICTED: peptidyl-pr ( 362) 367 94.8 1.5e-19 XP_011528351 (OMIM: 607588) PREDICTED: peptidyl-pr ( 438) 367 94.9 1.7e-19 XP_011528353 (OMIM: 607588) PREDICTED: peptidyl-pr ( 438) 367 94.9 1.7e-19 >>NP_066953 (OMIM: 123840) peptidyl-prolyl cis-trans iso (165 aa) initn: 1130 init1: 1130 opt: 1130 Z-score: 1447.3 bits: 274.1 E(85289): 7.1e-74 Smith-Waterman score: 1130; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165) 10 20 30 40 50 60 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE 70 80 90 100 110 120 130 140 150 160 pF1KB8 WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE ::::::::::::::::::::::::::::::::::::::::::::: NP_066 WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 130 140 150 160 >>NP_001137504 (OMIM: 608608) peptidyl-prolyl cis-trans (164 aa) initn: 972 init1: 954 opt: 954 Z-score: 1223.5 bits: 232.7 E(85289): 2.1e-61 Smith-Waterman score: 954; 84.8% identity (94.5% similar) in 164 aa overlap (1-164:1-164) 10 20 30 40 50 60 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF ::: .:::.:. ::.::::.:..:::::.::::::::::::::::: ::::::::::::: NP_001 MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE ::::::::: :::: ::::::::.:::.: :::: ::::::::::::::::::::.:::: NP_001 MCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTE 70 80 90 100 110 120 130 140 150 160 pF1KB8 WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE :::::::.:::::: .:::::::.:: ::.:::::::::::::. NP_001 WLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF 130 140 150 160 >>NP_005720 (OMIM: 604486) peptidyl-prolyl cis-trans iso (207 aa) initn: 893 init1: 893 opt: 893 Z-score: 1144.5 bits: 218.4 E(85289): 5.2e-57 Smith-Waterman score: 893; 76.5% identity (91.4% similar) in 162 aa overlap (3-164:45-206) 10 20 30 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKT :: :..:. ..:.::::: .:: :: :::: NP_005 SVPRSVPLRLPAARACSKGSGDPSSSSSSGNPLVYLDVDANGKPLGRVVLELKADVVPKT 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 AENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKH ::::::: ::::::::::: :::.::.::::.:::: ::::::::::: .: :::: ::: NP_005 AENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKH 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 TGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKT .:::.::::::::::::::::::: ::.::::::::::.:::::..:. .: :::..:.: NP_005 VGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGRT 140 150 160 170 180 190 160 pF1KB8 SKKITIADCGQLE ::::.:.::::: NP_005 SKKIVITDCGQLS 200 >>XP_016855541 (OMIM: 602435) PREDICTED: peptidyl-prolyl (217 aa) initn: 821 init1: 790 opt: 790 Z-score: 1013.3 bits: 194.2 E(85289): 1.1e-49 Smith-Waterman score: 790; 67.7% identity (85.7% similar) in 161 aa overlap (3-163:55-215) 10 20 30 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKT :: :..:: . ..: ::... : .: :: : XP_016 TLEENKEEEGSEPPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMT 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB8 AENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKH ::::: : : :::::.::: :::::: ::::::::: :::::::::::.::.:::::::: XP_016 AENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKH 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB8 TGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKT ::::.:::::.::::::::::. ::.::::::::::.: ::..... .: ::..:: XP_016 TGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKP 150 160 170 180 190 200 160 pF1KB8 SKKITIADCGQLE ..:. :::::. XP_016 KQKVIIADCGEYV 210 >>NP_006103 (OMIM: 602435) peptidyl-prolyl cis-trans iso (301 aa) initn: 806 init1: 790 opt: 790 Z-score: 1011.3 bits: 194.3 E(85289): 1.4e-49 Smith-Waterman score: 790; 67.7% identity (85.7% similar) in 161 aa overlap (3-163:139-299) 10 20 30 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKT :: :..:: . ..: ::... : .: :: : NP_006 TLEENKEEEGSEPPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMT 110 120 130 140 150 160 40 50 60 70 80 90 pF1KB8 AENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKH ::::: : : :::::.::: :::::: ::::::::: :::::::::::.::.:::::::: NP_006 AENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKH 170 180 190 200 210 220 100 110 120 130 140 150 pF1KB8 TGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKT ::::.:::::.::::::::::. ::.::::::::::.: ::..... .: ::..:: NP_006 TGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKP 230 240 250 260 270 280 160 pF1KB8 SKKITIADCGQLE ..:. :::::. NP_006 KQKVIIADCGEYV 290 300 >>XP_006710353 (OMIM: 602435) PREDICTED: peptidyl-prolyl (288 aa) initn: 781 init1: 765 opt: 774 Z-score: 991.2 bits: 190.5 E(85289): 1.8e-48 Smith-Waterman score: 774; 67.7% identity (86.1% similar) in 158 aa overlap (6-163:129-286) 10 20 30 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAEN :..:: . ..: ::... : .: :: :::: XP_006 DDWLKKFSGKTLEENKEEEGSEPPKAETQEVYMDIKIGNKPAGRIQMLLRSDVVPMTAEN 100 110 120 130 140 150 40 50 60 70 80 90 pF1KB8 FRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGP :: : : :::::.::: :::::: ::::::::: :::::::::::.::.::::::::::: XP_006 FRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGP 160 170 180 190 200 210 100 110 120 130 140 150 pF1KB8 GILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKK :.:::::.::::::::::. ::.::::::::::.: ::..... .: ::..:: ..: XP_006 GLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPKQK 220 230 240 250 260 270 160 pF1KB8 ITIADCGQLE . :::::. XP_006 VIIADCGEYV 280 >>XP_011509880 (OMIM: 601181,608033) PREDICTED: E3 SUMO- (2281 aa) initn: 811 init1: 773 opt: 773 Z-score: 977.1 bits: 190.9 E(85289): 1.1e-47 Smith-Waterman score: 773; 66.7% identity (87.7% similar) in 162 aa overlap (3-164:2120-2281) 10 20 30 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKT ::.::::. .:::::::...:::.. ::.: XP_011 FKKTFEECQQNLMKLQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRT 2090 2100 2110 2120 2130 2140 40 50 60 70 80 90 pF1KB8 AENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKH ::::::: :::::::.:.: :::.:: :.:::::.:.:.::::.::::.::::::: .:: XP_011 AENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKH 2150 2160 2170 2180 2190 2200 100 110 120 130 140 150 pF1KB8 TGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKT ::::.::::: : :::.::: : :.: :: :::::: ::.::. :. .: ::: .:.. XP_011 TGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSV 2210 2220 2230 2240 2250 2260 160 pF1KB8 SKKITIADCGQLE ..:::..:::. XP_011 CRRITITECGQI 2270 2280 >>XP_005264064 (OMIM: 601181,608033) PREDICTED: E3 SUMO- (2282 aa) initn: 811 init1: 773 opt: 773 Z-score: 977.1 bits: 190.9 E(85289): 1.1e-47 Smith-Waterman score: 773; 66.7% identity (87.7% similar) in 162 aa overlap (3-164:2121-2282) 10 20 30 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKT ::.::::. .:::::::...:::.. ::.: XP_005 FKKTFEECQQNLMKLQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRT 2100 2110 2120 2130 2140 2150 40 50 60 70 80 90 pF1KB8 AENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKH ::::::: :::::::.:.: :::.:: :.:::::.:.:.::::.::::.::::::: .:: XP_005 AENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKH 2160 2170 2180 2190 2200 2210 100 110 120 130 140 150 pF1KB8 TGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKT ::::.::::: : :::.::: : :.: :: :::::: ::.::. :. .: ::: .:.. XP_005 TGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSV 2220 2230 2240 2250 2260 2270 160 pF1KB8 SKKITIADCGQLE ..:::..:::. XP_005 CRRITITECGQI 2280 >>XP_011509878 (OMIM: 601181,608033) PREDICTED: E3 SUMO- (3199 aa) initn: 801 init1: 773 opt: 773 Z-score: 975.0 bits: 191.0 E(85289): 1.4e-47 Smith-Waterman score: 773; 66.7% identity (87.7% similar) in 162 aa overlap (3-164:3038-3199) 10 20 30 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKT ::.::::. .:::::::...:::.. ::.: XP_011 FKKTFEECQQNLMKLQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRT 3010 3020 3030 3040 3050 3060 40 50 60 70 80 90 pF1KB8 AENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKH ::::::: :::::::.:.: :::.:: :.:::::.:.:.::::.::::.::::::: .:: XP_011 AENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKH 3070 3080 3090 3100 3110 3120 100 110 120 130 140 150 pF1KB8 TGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKT ::::.::::: : :::.::: : :.: :: :::::: ::.::. :. .: ::: .:.. XP_011 TGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSV 3130 3140 3150 3160 3170 3180 160 pF1KB8 SKKITIADCGQLE ..:::..:::. XP_011 CRRITITECGQI 3190 >>NP_006258 (OMIM: 601181,608033) E3 SUMO-protein ligase (3224 aa) initn: 801 init1: 773 opt: 773 Z-score: 975.0 bits: 191.0 E(85289): 1.4e-47 Smith-Waterman score: 773; 66.7% identity (87.7% similar) in 162 aa overlap (3-164:3063-3224) 10 20 30 pF1KB8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKT ::.::::. .:::::::...:::.. ::.: NP_006 FKKTFEECQQNLMKLQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRT 3040 3050 3060 3070 3080 3090 40 50 60 70 80 90 pF1KB8 AENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKH ::::::: :::::::.:.: :::.:: :.:::::.:.:.::::.::::.::::::: .:: NP_006 AENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKH 3100 3110 3120 3130 3140 3150 100 110 120 130 140 150 pF1KB8 TGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKT ::::.::::: : :::.::: : :.: :: :::::: ::.::. :. .: ::: .:.. NP_006 TGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSV 3160 3170 3180 3190 3200 3210 160 pF1KB8 SKKITIADCGQLE ..:::..:::. NP_006 CRRITITECGQI 3220 165 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:27:54 2016 done: Fri Nov 4 10:27:55 2016 Total Scan time: 4.400 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]