FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8199, 206 aa 1>>>pF1KB8199 206 - 206 aa - 206 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4400+/-0.00028; mu= 15.6326+/- 0.018 mean_var=99.1516+/-19.994, 0's: 0 Z-trim(120.8): 12 B-trim: 0 in 0/58 Lambda= 0.128802 statistics sampled from 36586 (36600) to 36586 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.429), width: 16 Scan time: 5.080 The best scores are: opt bits E(85289) NP_001032726 (OMIM: 602542) transcription factor B ( 206) 1334 257.0 1.5e-68 NP_001198 (OMIM: 602542) transcription factor BTF3 ( 162) 1015 197.6 9.1e-51 NP_001106673 (OMIM: 601234) nascent polypeptide-as ( 215) 165 39.8 0.0039 NP_001307122 (OMIM: 601234) nascent polypeptide-as ( 215) 165 39.8 0.0039 NP_005585 (OMIM: 601234) nascent polypeptide-assoc ( 215) 165 39.8 0.0039 NP_001106672 (OMIM: 601234) nascent polypeptide-as ( 215) 165 39.8 0.0039 XP_006719481 (OMIM: 601234) PREDICTED: nascent pol ( 219) 165 39.8 0.004 NP_001307123 (OMIM: 601234) nascent polypeptide-as ( 219) 165 39.8 0.004 XP_006719483 (OMIM: 601234) PREDICTED: nascent pol ( 219) 165 39.8 0.004 >>NP_001032726 (OMIM: 602542) transcription factor BTF3 (206 aa) initn: 1334 init1: 1334 opt: 1334 Z-score: 1351.5 bits: 257.0 E(85289): 1.5e-68 Smith-Waterman score: 1334; 100.0% identity (100.0% similar) in 206 aa overlap (1-206:1-206) 10 20 30 40 50 60 pF1KB8 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPL 130 140 150 160 170 180 190 200 pF1KB8 ATGEDDDDEVPDLVENFDEASKNEAN :::::::::::::::::::::::::: NP_001 ATGEDDDDEVPDLVENFDEASKNEAN 190 200 >>NP_001198 (OMIM: 602542) transcription factor BTF3 iso (162 aa) initn: 1015 init1: 1015 opt: 1015 Z-score: 1032.4 bits: 197.6 E(85289): 9.1e-51 Smith-Waterman score: 1015; 100.0% identity (100.0% similar) in 162 aa overlap (45-206:1-162) 20 30 40 50 60 70 pF1KB8 RGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKK :::::::::::::::::::::::::::::: NP_001 MKETIMNQEKLAKLQAQVRIGGKGTARRKK 10 20 30 80 90 100 110 120 130 pF1KB8 KVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTI 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 TGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDDDDEVPDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDDDDEVPDLV 100 110 120 130 140 150 200 pF1KB8 ENFDEASKNEAN :::::::::::: NP_001 ENFDEASKNEAN 160 >>NP_001106673 (OMIM: 601234) nascent polypeptide-associ (215 aa) initn: 70 init1: 54 opt: 165 Z-score: 177.3 bits: 39.8 E(85289): 0.0039 Smith-Waterman score: 165; 23.6% identity (60.5% similar) in 195 aa overlap (16-206:3-189) 10 20 30 40 50 60 pF1KB8 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA :.: :. : : :: . :. : : . :.. . :. . :: NP_001 MPGEATETVPATEQELPQPQAETGS-GTESDSDESVPELEEQDSTQA 10 20 30 40 70 80 90 100 110 pF1KB8 QVRIGGKGTARR--KKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHF .. . ..: . .. : . . ..:: . ...:::. ...:. .:.. ... .. . NP_001 TTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 NNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKA ..: : : :..:. . :.:. ..:... ::.: ... .::. . . . .. NP_001 TKPDVYKSPASDTYIVFGEAKIEDLSQQ-----AQLAAAE--KFKVQGEAVSNIQENTQT 110 120 130 140 150 180 190 200 pF1KB8 PLATGEDDDDEVPDL-VENFD-EASKNEAN : . :....:: . :: : : ..:: NP_001 PTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 160 170 180 190 200 210 >>NP_001307122 (OMIM: 601234) nascent polypeptide-associ (215 aa) initn: 70 init1: 54 opt: 165 Z-score: 177.3 bits: 39.8 E(85289): 0.0039 Smith-Waterman score: 165; 23.6% identity (60.5% similar) in 195 aa overlap (16-206:3-189) 10 20 30 40 50 60 pF1KB8 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA :.: :. : : :: . :. : : . :.. . :. . :: NP_001 MPGEATETVPATEQELPQPQAETGS-GTESDSDESVPELEEQDSTQA 10 20 30 40 70 80 90 100 110 pF1KB8 QVRIGGKGTARR--KKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHF .. . ..: . .. : . . ..:: . ...:::. ...:. .:.. ... .. . NP_001 TTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 NNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKA ..: : : :..:. . :.:. ..:... ::.: ... .::. . . . .. NP_001 TKPDVYKSPASDTYIVFGEAKIEDLSQQ-----AQLAAAE--KFKVQGEAVSNIQENTQT 110 120 130 140 150 180 190 200 pF1KB8 PLATGEDDDDEVPDL-VENFD-EASKNEAN : . :....:: . :: : : ..:: NP_001 PTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 160 170 180 190 200 210 >>NP_005585 (OMIM: 601234) nascent polypeptide-associate (215 aa) initn: 70 init1: 54 opt: 165 Z-score: 177.3 bits: 39.8 E(85289): 0.0039 Smith-Waterman score: 165; 23.6% identity (60.5% similar) in 195 aa overlap (16-206:3-189) 10 20 30 40 50 60 pF1KB8 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA :.: :. : : :: . :. : : . :.. . :. . :: NP_005 MPGEATETVPATEQELPQPQAETGS-GTESDSDESVPELEEQDSTQA 10 20 30 40 70 80 90 100 110 pF1KB8 QVRIGGKGTARR--KKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHF .. . ..: . .. : . . ..:: . ...:::. ...:. .:.. ... .. . NP_005 TTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 NNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKA ..: : : :..:. . :.:. ..:... ::.: ... .::. . . . .. NP_005 TKPDVYKSPASDTYIVFGEAKIEDLSQQ-----AQLAAAE--KFKVQGEAVSNIQENTQT 110 120 130 140 150 180 190 200 pF1KB8 PLATGEDDDDEVPDL-VENFD-EASKNEAN : . :....:: . :: : : ..:: NP_005 PTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 160 170 180 190 200 210 >>NP_001106672 (OMIM: 601234) nascent polypeptide-associ (215 aa) initn: 70 init1: 54 opt: 165 Z-score: 177.3 bits: 39.8 E(85289): 0.0039 Smith-Waterman score: 165; 23.6% identity (60.5% similar) in 195 aa overlap (16-206:3-189) 10 20 30 40 50 60 pF1KB8 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA :.: :. : : :: . :. : : . :.. . :. . :: NP_001 MPGEATETVPATEQELPQPQAETGS-GTESDSDESVPELEEQDSTQA 10 20 30 40 70 80 90 100 110 pF1KB8 QVRIGGKGTARR--KKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHF .. . ..: . .. : . . ..:: . ...:::. ...:. .:.. ... .. . NP_001 TTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 NNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKA ..: : : :..:. . :.:. ..:... ::.: ... .::. . . . .. NP_001 TKPDVYKSPASDTYIVFGEAKIEDLSQQ-----AQLAAAE--KFKVQGEAVSNIQENTQT 110 120 130 140 150 180 190 200 pF1KB8 PLATGEDDDDEVPDL-VENFD-EASKNEAN : . :....:: . :: : : ..:: NP_001 PTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 160 170 180 190 200 210 >>XP_006719481 (OMIM: 601234) PREDICTED: nascent polypep (219 aa) initn: 70 init1: 54 opt: 165 Z-score: 177.2 bits: 39.8 E(85289): 0.004 Smith-Waterman score: 165; 23.6% identity (60.5% similar) in 195 aa overlap (16-206:3-189) 10 20 30 40 50 60 pF1KB8 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA :.: :. : : :: . :. : : . :.. . :. . :: XP_006 MPGEATETVPATEQELPQPQAETGS-GTESDSDESVPELEEQDSTQA 10 20 30 40 70 80 90 100 110 pF1KB8 QVRIGGKGTARR--KKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHF .. . ..: . .. : . . ..:: . ...:::. ...:. .:.. ... .. . XP_006 TTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 NNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKA ..: : : :..:. . :.:. ..:... ::.: ... .::. . . . .. XP_006 TKPDVYKSPASDTYIVFGEAKIEDLSQQ-----AQLAAAE--KFKVQGEAVSNIQENTQT 110 120 130 140 150 180 190 200 pF1KB8 PLATGEDDDDEVPDL-VENFD-EASKNEAN : . :....:: . :: : : ..:: XP_006 PTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMVSVQAFVP 160 170 180 190 200 210 >>NP_001307123 (OMIM: 601234) nascent polypeptide-associ (219 aa) initn: 70 init1: 54 opt: 165 Z-score: 177.2 bits: 39.8 E(85289): 0.004 Smith-Waterman score: 165; 23.6% identity (60.5% similar) in 195 aa overlap (16-206:3-189) 10 20 30 40 50 60 pF1KB8 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA :.: :. : : :: . :. : : . :.. . :. . :: NP_001 MPGEATETVPATEQELPQPQAETGS-GTESDSDESVPELEEQDSTQA 10 20 30 40 70 80 90 100 110 pF1KB8 QVRIGGKGTARR--KKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHF .. . ..: . .. : . . ..:: . ...:::. ...:. .:.. ... .. . NP_001 TTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 NNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKA ..: : : :..:. . :.:. ..:... ::.: ... .::. . . . .. NP_001 TKPDVYKSPASDTYIVFGEAKIEDLSQQ-----AQLAAAE--KFKVQGEAVSNIQENTQT 110 120 130 140 150 180 190 200 pF1KB8 PLATGEDDDDEVPDL-VENFD-EASKNEAN : . :....:: . :: : : ..:: NP_001 PTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMVSVQAFVP 160 170 180 190 200 210 >>XP_006719483 (OMIM: 601234) PREDICTED: nascent polypep (219 aa) initn: 70 init1: 54 opt: 165 Z-score: 177.2 bits: 39.8 E(85289): 0.004 Smith-Waterman score: 165; 23.6% identity (60.5% similar) in 195 aa overlap (16-206:3-189) 10 20 30 40 50 60 pF1KB8 MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQA :.: :. : : :: . :. : : . :.. . :. . :: XP_006 MPGEATETVPATEQELPQPQAETGS-GTESDSDESVPELEEQDSTQA 10 20 30 40 70 80 90 100 110 pF1KB8 QVRIGGKGTARR--KKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHF .. . ..: . .. : . . ..:: . ...:::. ...:. .:.. ... .. . XP_006 TTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 NNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKA ..: : : :..:. . :.:. ..:... ::.: ... .::. . . . .. XP_006 TKPDVYKSPASDTYIVFGEAKIEDLSQQ-----AQLAAAE--KFKVQGEAVSNIQENTQT 110 120 130 140 150 180 190 200 pF1KB8 PLATGEDDDDEVPDL-VENFD-EASKNEAN : . :....:: . :: : : ..:: XP_006 PTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMVSVQAFVP 160 170 180 190 200 210 206 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:29:23 2016 done: Fri Nov 4 10:29:24 2016 Total Scan time: 5.080 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]