FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8202, 194 aa 1>>>pF1KB8202 194 - 194 aa - 194 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.5626+/-0.000339; mu= -7.7452+/- 0.021 mean_var=377.9548+/-78.670, 0's: 0 Z-trim(126.9): 2 B-trim: 1714 in 1/61 Lambda= 0.065971 statistics sampled from 53987 (53992) to 53987 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.867), E-opt: 0.2 (0.633), width: 16 Scan time: 5.130 The best scores are: opt bits E(85289) NP_703151 (OMIM: 612385) mediator of RNA polymeras ( 211) 1388 144.3 1.3e-34 NP_001304007 (OMIM: 612385) mediator of RNA polyme ( 261) 1370 142.7 4.9e-34 >>NP_703151 (OMIM: 612385) mediator of RNA polymerase II (211 aa) initn: 1388 init1: 1388 opt: 1388 Z-score: 742.4 bits: 144.3 E(85289): 1.3e-34 Smith-Waterman score: 1388; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:18-211) 10 20 30 40 pF1KB8 MENFTALFGAQADPPPPPTALGFGPGKPPPPPPPPAGGGPGTA ::::::::::::::::::::::::::::::::::::::::::: NP_703 MKITNGRHGDSAGAEGTMENFTALFGAQADPPPPPTALGFGPGKPPPPPPPPAGGGPGTA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 PPPTAATAPPGADKSGAGCGPFYLMRELPGSTELTGSTNLITHYNLEQAYNKFCGKKVKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_703 PPPTAATAPPGADKSGAGCGPFYLMRELPGSTELTGSTNLITHYNLEQAYNKFCGKKVKE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 KLSNFLPDLPGMIDLPGSHDNSSLRSLIEKPPILSSSFNPITGTMLAGFRLHTGPLPEQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_703 KLSNFLPDLPGMIDLPGSHDNSSLRSLIEKPPILSSSFNPITGTMLAGFRLHTGPLPEQC 130 140 150 160 170 180 170 180 190 pF1KB8 RLMHIQPPKKKNKHKHKQSRTQDPVPPGKPS ::::::::::::::::::::::::::::::: NP_703 RLMHIQPPKKKNKHKHKQSRTQDPVPPGKPS 190 200 210 >>NP_001304007 (OMIM: 612385) mediator of RNA polymerase (261 aa) initn: 1370 init1: 1370 opt: 1370 Z-score: 732.0 bits: 142.7 E(85289): 4.9e-34 Smith-Waterman score: 1370; 99.0% identity (99.0% similar) in 194 aa overlap (1-194:18-211) 10 20 30 40 pF1KB8 MENFTALFGAQADPPPPPTALGFGPGKPPPPPPPPAGGGPGTA ::::::::::::::::::::::::::::::::::::::::::: NP_001 MKITNGRHGDSAGAEGTMENFTALFGAQADPPPPPTALGFGPGKPPPPPPPPAGGGPGTA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 PPPTAATAPPGADKSGAGCGPFYLMRELPGSTELTGSTNLITHYNLEQAYNKFCGKKVKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPTAATAPPGADKSGAGCGPFYLMRELPGSTELTGSTNLITHYNLEQAYNKFCGKKVKE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 KLSNFLPDLPGMIDLPGSHDNSSLRSLIEKPPILSSSFNPITGTMLAGFRLHTGPLPEQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLSNFLPDLPGMIDLPGSHDNSSLRSLIEKPPILSSSFNPITGTMLAGFRLHTGPLPEQC 130 140 150 160 170 180 170 180 190 pF1KB8 RLMHIQPPKKKNKHKHKQSRTQDPVPPGKPS ::::::::::::::::::::::::::: :: NP_001 RLMHIQPPKKKNKHKHKQSRTQDPVPPETPSDSDHKKKKKKKEEDPERKRKKKEKKKKKN 190 200 210 220 230 240 NP_001 RHSPDHPGMGSSQASSSSSLR 250 260 194 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:31:09 2016 done: Fri Nov 4 10:31:09 2016 Total Scan time: 5.130 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]