FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8204, 470 aa 1>>>pF1KB8204 470 - 470 aa - 470 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2247+/-0.000406; mu= -2.2842+/- 0.025 mean_var=300.8966+/-61.849, 0's: 0 Z-trim(121.4): 12 B-trim: 725 in 1/55 Lambda= 0.073938 statistics sampled from 38051 (38063) to 38051 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.446), width: 16 Scan time: 7.560 The best scores are: opt bits E(85289) NP_003069 (OMIM: 601737) SWI/SNF-related matrix-as ( 470) 3176 352.1 2e-96 NP_001003802 (OMIM: 601737) SWI/SNF-related matrix ( 470) 3176 352.1 2e-96 NP_001003801 (OMIM: 601737) SWI/SNF-related matrix ( 483) 3082 342.0 2.1e-93 XP_011514823 (OMIM: 601737) PREDICTED: SWI/SNF-rel ( 381) 2535 283.6 6.4e-76 NP_003067 (OMIM: 601735) SWI/SNF-related matrix-as ( 515) 2363 265.4 2.7e-70 XP_016868045 (OMIM: 601737) PREDICTED: SWI/SNF-rel ( 318) 1954 221.6 2.5e-57 NP_620710 (OMIM: 601735) SWI/SNF-related matrix-as ( 474) 1866 212.3 2.3e-54 NP_001091896 (OMIM: 601736) SWI/SNF-related matrix ( 531) 1855 211.2 5.6e-54 NP_001317369 (OMIM: 601736) SWI/SNF-related matrix ( 483) 1849 210.5 8.2e-54 NP_001317368 (OMIM: 601736) SWI/SNF-related matrix ( 456) 1817 207.1 8.3e-53 XP_005269164 (OMIM: 601735) PREDICTED: SWI/SNF-rel ( 474) 1669 191.3 4.9e-48 XP_011536997 (OMIM: 601735) PREDICTED: SWI/SNF-rel ( 265) 949 114.3 4.1e-25 >>NP_003069 (OMIM: 601737) SWI/SNF-related matrix-associ (470 aa) initn: 3176 init1: 3176 opt: 3176 Z-score: 1852.3 bits: 352.1 E(85289): 2e-96 Smith-Waterman score: 3176; 100.0% identity (100.0% similar) in 470 aa overlap (1-470:1-470) 10 20 30 40 50 60 pF1KB8 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGLAPAGMEPARKRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGLAPAGMEPARKRAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 IFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKV 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 MTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT :::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT 430 440 450 460 470 >>NP_001003802 (OMIM: 601737) SWI/SNF-related matrix-ass (470 aa) initn: 3176 init1: 3176 opt: 3176 Z-score: 1852.3 bits: 352.1 E(85289): 2e-96 Smith-Waterman score: 3176; 100.0% identity (100.0% similar) in 470 aa overlap (1-470:1-470) 10 20 30 40 50 60 pF1KB8 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGLAPAGMEPARKRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGLAPAGMEPARKRAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 IFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKV 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 MTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT 430 440 450 460 470 >>NP_001003801 (OMIM: 601737) SWI/SNF-related matrix-ass (483 aa) initn: 3082 init1: 3082 opt: 3082 Z-score: 1797.9 bits: 342.0 E(85289): 2.1e-93 Smith-Waterman score: 3082; 100.0% identity (100.0% similar) in 457 aa overlap (14-470:27-483) 10 20 30 40 pF1KB8 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGL :::::::::::::::::::::::::::::::::: NP_001 MAADEVAGGARKATKSKLFEFLVHGVRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 APAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQ 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 AYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 SWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 KRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSH 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 DKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDI 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 DVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYV 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB8 QDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVV 430 440 450 460 470 480 470 pF1KB8 RNT ::: NP_001 RNT >>XP_011514823 (OMIM: 601737) PREDICTED: SWI/SNF-related (381 aa) initn: 2535 init1: 2535 opt: 2535 Z-score: 1484.0 bits: 283.6 E(85289): 6.4e-76 Smith-Waterman score: 2535; 100.0% identity (100.0% similar) in 381 aa overlap (90-470:1-381) 60 70 80 90 100 110 pF1KB8 APPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKL :::::::::::::::::::::::::::::: XP_011 MADKILPQRIRELVPESQAYMDLLAFERKL 10 20 30 120 130 140 150 160 170 pF1KB8 DQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLD 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB8 DPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB8 LLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQ 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB8 QIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQM 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB8 SSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLK 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB8 VMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT 340 350 360 370 380 >>NP_003067 (OMIM: 601735) SWI/SNF-related matrix-associ (515 aa) initn: 2374 init1: 1619 opt: 2363 Z-score: 1383.0 bits: 265.4 E(85289): 2.7e-70 Smith-Waterman score: 2363; 74.1% identity (88.0% similar) in 475 aa overlap (3-470:54-515) 10 20 30 pF1KB8 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGP :: .: :::: :.:: :: ::: NP_003 AAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYP-----RPGMLPGSRMTPQGPSMGP 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 PGSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMAD :: : :.:.:::::: .::. .::: : : : : : : : : . :...::..:::: NP_003 PG--YGGNPSVRPGLAQSGMDQSRKR--PAPQQIQ-QVQQQAVQN---RNHNAKKKKMAD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTF :::::::::::::::::::::::::::::::::::.:::::::::.:::::::..::::: NP_003 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTF 140 150 160 170 180 190 160 170 180 190 200 pF1KB8 NPAKPDAEDSDGSIASWELRVEGKLLDDP-------SKQKRKFSSFFKSLVIELDKDLYG :::: ::::..:..:::::::::.::.: .::::::::::::::::::::::: NP_003 NPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYG 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB8 PDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQ ::::::::::: :::::::::::::::..::::.::::::::::::::::::::::.::: NP_003 PDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQ 260 270 280 290 300 310 270 280 290 300 310 320 pF1KB8 SRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDP .: .:.::::::.::..::: :..:.. :::.::::. :.::::::::: :::.::.: NP_003 TRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEP 320 330 340 350 360 370 330 340 350 360 370 380 pF1KB8 IVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIES :.:::::::::.::::::::::::::.. :: ::.:::::::.::::..::.:::::::. NP_003 IIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIET 380 390 400 410 420 430 390 400 410 420 430 440 pF1KB8 INQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEA ::::: ::.:::::.:::.:...: :.:: ::::.::::.:::::::::::: :::.::: NP_003 INQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEA 440 450 460 470 480 490 450 460 470 pF1KB8 VSRYFYCKIQQRRQELEQSLVVRNT : :::: :.:::::::::.: .::: NP_003 VCRYFYSKVQQRRQELEQALGIRNT 500 510 >>XP_016868045 (OMIM: 601737) PREDICTED: SWI/SNF-related (318 aa) initn: 1944 init1: 1944 opt: 1954 Z-score: 1150.1 bits: 221.6 E(85289): 2.5e-57 Smith-Waterman score: 1954; 93.4% identity (94.7% similar) in 318 aa overlap (157-470:5-318) 130 140 150 160 170 180 pF1KB8 RVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSI----ASWELRVEGKLLDDPS : : :: .:: . : .. :: XP_016 MLRIPTAALPPGSYGWRGSSWMMYVPAQ----PS 10 20 30 190 200 210 220 230 240 pF1KB8 KQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLM 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB8 LDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIF 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB8 DCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSF 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB8 LLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMT 220 230 240 250 260 270 430 440 450 460 470 pF1KB8 DVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT 280 290 300 310 >>NP_620710 (OMIM: 601735) SWI/SNF-related matrix-associ (474 aa) initn: 1877 init1: 1113 opt: 1866 Z-score: 1097.0 bits: 212.3 E(85289): 2.3e-54 Smith-Waterman score: 2061; 67.8% identity (80.0% similar) in 475 aa overlap (3-470:54-474) 10 20 30 pF1KB8 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGP :: .: :::: :.:: :: ::: NP_620 AAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYP-----RPGMLPGSRMTPQGPSMGP 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 PGSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMAD :: : :.:.:::::: .::. .::: : : : : : : : : . :...::..:::: NP_620 PG--YGGNPSVRPGLAQSGMDQSRKR--PAPQQIQ-QVQQQAVQN---RNHNAKKKKMAD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTF :::::::::::::::::::::::::::::::::::.:::::::::.:::::::..::::: NP_620 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTF 140 150 160 170 180 190 160 170 180 190 200 pF1KB8 NPAKPDAEDSDGSIASWELRVEGKLLDDP-------SKQKRKFSSFFKSLVIELDKDLYG :::: ::::..:..:::::::::.::.: .::::::::::::::::::::::: NP_620 NPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYG 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB8 PDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQ ::::::::::: :::::::::::::::..::::.::::::::::::::::::::::.::: NP_620 PDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQ 260 270 280 290 300 310 270 280 290 300 310 320 pF1KB8 SRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDP .: .:.::::::.::..::: :..:.. :::.::::. :.::::::::: :::.::.: NP_620 TRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEP 320 330 340 350 360 370 330 340 350 360 370 380 pF1KB8 IVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIES :.:::::::::.::::::::::::::.. :: ::.:::::::.::::..::.: NP_620 IIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNK------- 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 INQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEA .::::.:::::::::::: :::.::: NP_620 ----------------------------------TMTDVVGNPEEERRAEFYFQPWAQEA 430 440 450 460 470 pF1KB8 VSRYFYCKIQQRRQELEQSLVVRNT : :::: :.:::::::::.: .::: NP_620 VCRYFYSKVQQRRQELEQALGIRNT 450 460 470 >>NP_001091896 (OMIM: 601736) SWI/SNF-related matrix-ass (531 aa) initn: 2197 init1: 1676 opt: 1855 Z-score: 1090.0 bits: 211.2 E(85289): 5.6e-54 Smith-Waterman score: 2259; 70.4% identity (84.6% similar) in 480 aa overlap (4-470:63-531) 10 20 30 pF1KB8 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGPP : : . ::::: : ::: : .::: NP_001 GPGMLPGPALRGPGPAGGVGGPGAAAFRPMGPAGPAAQYQRPGMSPGNRMPMAGLQVGPP 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB8 -GSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMAD :::. .. .:::. :. :.: ::: : ::: : ::. :. ::::::: NP_001 AGSPFGAAAPLRPGMPPTMMDPFRKRLLVP----QAQ------PPMPAQRRGLKRRKMAD 100 110 120 130 140 100 110 120 130 140 150 pF1KB8 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTF :.::::::::::::::::::::::::::::: :::..::::.:.:. ::::::.:::::: NP_001 KVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTF 150 160 170 180 190 200 160 170 180 190 200 pF1KB8 NPAKPDAEDSDGS------------IASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELD .:.: .. :: :. .:::::::::::::::::::::::::::::::::: NP_001 SPSKAEG-DSAGTAGTPGGTPAGDKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELD 210 220 230 240 250 260 210 220 230 240 250 260 pF1KB8 KDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLL :.::::::::::::: :::::::::::::::::.:.::::::::.::::.:::::::::: NP_001 KELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLL 270 280 290 300 310 320 270 280 290 300 310 320 pF1KB8 GLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTALL :.:::.:.::.:::: :.: :.:::.:..:::: ..::.:::.: ::.:::::..:..:: NP_001 GVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLL 330 340 350 360 370 380 330 340 350 360 370 380 pF1KB8 LPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIH ::::::::::::::.::::::::::::::..:::.:::.:: ::.:::::..:: ::: NP_001 QHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIH 390 400 410 420 430 440 390 400 410 420 430 440 pF1KB8 ETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQP :::::::::: ::::::::: ::. ..:. :::: ::::..::: ::::::::: ::::: NP_001 ETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQP 450 460 470 480 490 500 450 460 470 pF1KB8 WSQEAVSRYFYCKIQQRRQELEQSLVVRNT :.::::.:... :.::::::::: : .: : NP_001 WAQEAVGRHIFAKVQQRRQELEQVLGIRLT 510 520 530 >>NP_001317369 (OMIM: 601736) SWI/SNF-related matrix-ass (483 aa) initn: 2197 init1: 1676 opt: 1849 Z-score: 1087.1 bits: 210.5 E(85289): 8.2e-54 Smith-Waterman score: 2253; 71.3% identity (85.6% similar) in 471 aa overlap (13-470:24-483) 10 20 30 40 pF1KB8 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGPP-GSPYMGSPAVRPGLA ::::: : ::: : .::: :::. .. .:::. NP_001 MGRRVGVEVTPRWAPQKCQGARPQRPGMSPGNRMPMAGLQVGPPAGSPFGAAAPLRPGMP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 PAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQA :. :.: ::: : ::: : ::. :. ::::::::.:::::::::::::: NP_001 PTMMDPFRKRLLVP----QAQ------PPMPAQRRGLKRRKMADKVLPQRIRELVPESQA 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 YMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGS--- ::::::::::::::: :::..::::.:.:. ::::::.::::::.:.: .. :: :. NP_001 YMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEG-DSAGTAGT 120 130 140 150 160 170 180 190 200 210 pF1KB8 ---------IASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRT .:::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 PGGTPAGDKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRM 170 180 190 200 210 220 220 230 240 250 260 270 pF1KB8 PTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQ :::::::::::::::::.:.::::::::.::::.:::::::::::.:::.:.::.:::: NP_001 PTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWL 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB8 YVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDP :.: :.:::.:..:::: ..::.:::.: ::.:::::..:..:: :::::::::::::: NP_001 YIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDP 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB8 SDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFM .::::::::::::::..:::.:::.:: ::.:::::..:: ::::::::::::: ::::: NP_001 NDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFM 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB8 LSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQ :::: ::. ..:. :::: ::::..::: ::::::::: ::::::.::::.:... :.:: NP_001 LSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQ 410 420 430 440 450 460 460 470 pF1KB8 RRQELEQSLVVRNT ::::::: : .: : NP_001 RRQELEQVLGIRLT 470 480 >>NP_001317368 (OMIM: 601736) SWI/SNF-related matrix-ass (456 aa) initn: 2215 init1: 1676 opt: 1817 Z-score: 1069.0 bits: 207.1 E(85289): 8.3e-53 Smith-Waterman score: 2221; 71.1% identity (85.4% similar) in 467 aa overlap (17-470:1-456) 10 20 30 40 50 pF1KB8 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGPP-GSPYMGSPAVRPGLAPAGMEPARKRA : : ::: : .::: :::. .. .:::. :. :.: ::: NP_001 MSPGNRMPMAGLQVGPPAGSPFGAAAPLRPGMPPTMMDPFRKRL 10 20 30 40 60 70 80 90 100 110 pF1KB8 APPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKL : ::: : ::. :. ::::::::.::::::::::::::::::::::::: NP_001 LVP----QAQ------PPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKL 50 60 70 80 90 120 130 140 150 160 pF1KB8 DQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGS------------IA :::: :::..::::.:.:. ::::::.::::::.:.: .. :: :. .: NP_001 DQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEG-DSAGTAGTPGGTPAGDKVA 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB8 SWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQV ::::::::::::::::::::::::::::::::::.::::::::::::: ::::::::::: NP_001 SWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQV 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB8 KRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSH ::::::.:.::::::::.::::.:::::::::::.:::.:.::.:::: :.: :.:::.: NP_001 KRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGH 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB8 DKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDI ..:::: ..::.:::.: ::.:::::..:..:: ::::::::::::::.:::::::::: NP_001 EREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYDI 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB8 DVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYV ::::..:::.:::.:: ::.:::::..:: ::::::::::::: ::::::::: ::. .. NP_001 DVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFI 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB8 QDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVV :. :::: ::::..::: ::::::::: ::::::.::::.:... :.::::::::: : . NP_001 QEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGI 400 410 420 430 440 450 470 pF1KB8 RNT : : NP_001 RLT 470 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:31:48 2016 done: Fri Nov 4 10:31:49 2016 Total Scan time: 7.560 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]