FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8205, 351 aa 1>>>pF1KB8205 351 - 351 aa - 351 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0481+/-0.00027; mu= 19.1082+/- 0.017 mean_var=75.8972+/-15.167, 0's: 0 Z-trim(120.7): 15 B-trim: 1214 in 1/56 Lambda= 0.147218 statistics sampled from 36236 (36252) to 36236 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.425), width: 16 Scan time: 7.740 The best scores are: opt bits E(85289) NP_000318 (OMIM: 180721,268000,608133) rod outer s ( 351) 2413 521.1 1.4e-147 NP_000313 (OMIM: 136880,169150,179605,608133,60816 ( 346) 812 181.1 3.2e-45 NP_620598 (OMIM: 179620,602243,609057) CD151 antig ( 253) 167 44.0 0.00044 NP_620599 (OMIM: 179620,602243,609057) CD151 antig ( 253) 167 44.0 0.00044 NP_001034579 (OMIM: 179620,602243,609057) CD151 an ( 253) 167 44.0 0.00044 NP_004348 (OMIM: 179620,602243,609057) CD151 antig ( 253) 167 44.0 0.00044 >>NP_000318 (OMIM: 180721,268000,608133) rod outer segme (351 aa) initn: 2413 init1: 2413 opt: 2413 Z-score: 2770.6 bits: 521.1 E(85289): 1.4e-147 Smith-Waterman score: 2413; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB8 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALEGLGGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALEGLGGVI 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 DAGGETQGYLFPSGLKDMLKTAWLQGGVACRPAPEEAPPGEAPPKEDLSEA ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DAGGETQGYLFPSGLKDMLKTAWLQGGVACRPAPEEAPPGEAPPKEDLSEA 310 320 330 340 350 >>NP_000313 (OMIM: 136880,169150,179605,608133,608161,61 (346 aa) initn: 768 init1: 666 opt: 812 Z-score: 932.9 bits: 181.1 E(85289): 3.2e-45 Smith-Waterman score: 812; 36.0% identity (69.8% similar) in 344 aa overlap (4-343:3-343) 10 20 30 40 50 60 pF1KB8 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFP .: . . . :..:::::::..:. .::: .:. . : ..::. . . : . NP_000 MALLKVKFDQKKRVKLAQGLWLMNWFSVLAGIIIFSLGLFLKIELRKRSDVMNNS-ESH 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVALG .:.. .. :... . .. .:. : : :. : : :. . . :..::: NP_000 FVPNSLIGMGVLSCVFNSLAGKICYDALDPAKYARWKPWLKPYLAICVLFNIILFLVALC 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 LALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGV : : :::...: .:: ... .:.::..::.: :. .: ::....::: .:..::: . NP_000 CFL-LRGSLENTLGQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 QWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSYAHPLFD ::.:.:::: ....: :::.:::.: ::.:::::::::: :::::.: ..... :: .: NP_000 QWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 PRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALEGLGGVI . . :::..::. .:: . ..: ...: . . .:... . .:::::::.:.:... NP_000 HQTEELNLWVRGCRAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPE 240 250 260 270 280 290 310 320 330 340 350 pF1KB8 DAGGETQGYLFPSGLKDMLKTAWLQG----GVACRPAPEEAPPGEAPPKEDLSEA .. .:.::.:. .. . : :.:.. : . . : : :.:: NP_000 ESESESQGWLLERSVPETWK-AFLESVKKLGKGNQVEAEGADAGQAPEAG 300 310 320 330 340 >>NP_620598 (OMIM: 179620,602243,609057) CD151 antigen [ (253 aa) initn: 143 init1: 116 opt: 167 Z-score: 194.4 bits: 44.0 E(85289): 0.00044 Smith-Waterman score: 184; 29.0% identity (52.7% similar) in 186 aa overlap (21-206:27-191) 10 20 30 40 50 pF1KB8 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLA .:: . : ..: :. : ..: ::.:: NP_620 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAG-LAVMAVGIWTLALKSDYISLLASGTYLA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PSCQFPVLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGL . .: ..::.:.. ::..: :. : : . ::. : NP_620 TAY---IL----VVAGTVVMVTGVLGCCATFKERRNLL----RLYFILLLIIFL-----L 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 LVVALGLALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGY ..: :: : .:. :.:.: ... : . ::: . ::.:: ..:::: .. NP_620 EIIAGILAYAYYQQLNTELKENLKDTMT--KRYHQPGHEAVTSAVDQLQQEFHCCGSNNS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 KDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSY .:: .:. :. . : : : : ..: .: NP_620 QDWRDSEWIRSQ--EAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEH 170 180 190 200 210 240 250 260 270 280 290 pF1KB8 AHPLFDPRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALE NP_620 LRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 220 230 240 250 >>NP_620599 (OMIM: 179620,602243,609057) CD151 antigen [ (253 aa) initn: 143 init1: 116 opt: 167 Z-score: 194.4 bits: 44.0 E(85289): 0.00044 Smith-Waterman score: 184; 29.0% identity (52.7% similar) in 186 aa overlap (21-206:27-191) 10 20 30 40 50 pF1KB8 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLA .:: . : ..: :. : ..: ::.:: NP_620 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAG-LAVMAVGIWTLALKSDYISLLASGTYLA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PSCQFPVLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGL . .: ..::.:.. ::..: :. : : . ::. : NP_620 TAY---IL----VVAGTVVMVTGVLGCCATFKERRNLL----RLYFILLLIIFL-----L 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 LVVALGLALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGY ..: :: : .:. :.:.: ... : . ::: . ::.:: ..:::: .. NP_620 EIIAGILAYAYYQQLNTELKENLKDTMT--KRYHQPGHEAVTSAVDQLQQEFHCCGSNNS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 KDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSY .:: .:. :. . : : : : ..: .: NP_620 QDWRDSEWIRSQ--EAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEH 170 180 190 200 210 240 250 260 270 280 290 pF1KB8 AHPLFDPRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALE NP_620 LRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 220 230 240 250 >>NP_001034579 (OMIM: 179620,602243,609057) CD151 antige (253 aa) initn: 143 init1: 116 opt: 167 Z-score: 194.4 bits: 44.0 E(85289): 0.00044 Smith-Waterman score: 184; 29.0% identity (52.7% similar) in 186 aa overlap (21-206:27-191) 10 20 30 40 50 pF1KB8 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLA .:: . : ..: :. : ..: ::.:: NP_001 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAG-LAVMAVGIWTLALKSDYISLLASGTYLA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PSCQFPVLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGL . .: ..::.:.. ::..: :. : : . ::. : NP_001 TAY---IL----VVAGTVVMVTGVLGCCATFKERRNLL----RLYFILLLIIFL-----L 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 LVVALGLALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGY ..: :: : .:. :.:.: ... : . ::: . ::.:: ..:::: .. NP_001 EIIAGILAYAYYQQLNTELKENLKDTMT--KRYHQPGHEAVTSAVDQLQQEFHCCGSNNS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 KDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSY .:: .:. :. . : : : : ..: .: NP_001 QDWRDSEWIRSQ--EAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEH 170 180 190 200 210 240 250 260 270 280 290 pF1KB8 AHPLFDPRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALE NP_001 LRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 220 230 240 250 >>NP_004348 (OMIM: 179620,602243,609057) CD151 antigen [ (253 aa) initn: 143 init1: 116 opt: 167 Z-score: 194.4 bits: 44.0 E(85289): 0.00044 Smith-Waterman score: 184; 29.0% identity (52.7% similar) in 186 aa overlap (21-206:27-191) 10 20 30 40 50 pF1KB8 MAPVLPLVLPLQPRIRLAQGLWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLA .:: . : ..: :. : ..: ::.:: NP_004 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAG-LAVMAVGIWTLALKSDYISLLASGTYLA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PSCQFPVLPQAALAAGAVALGTGLVGVGASRASLNAALYPPWRGVLGPLLVAGTAGGGGL . .: ..::.:.. ::..: :. : : . ::. : NP_004 TAY---IL----VVAGTVVMVTGVLGCCATFKERRNLL----RLYFILLLIIFL-----L 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 LVVALGLALALPGSLDEALEEGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGY ..: :: : .:. :.:.: ... : . ::: . ::.:: ..:::: .. NP_004 EIIAGILAYAYYQQLNTELKENLKDTMT--KRYHQPGHEAVTSAVDQLQQEFHCCGSNNS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 KDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFSCCNPHSPRPCLQNRLSDSY .:: .:. :. . : : : : ..: .: NP_004 QDWRDSEWIRSQ--EAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEH 170 180 190 200 210 240 250 260 270 280 290 pF1KB8 AHPLFDPRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQALVLLGLRYLQTALE NP_004 LRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 220 230 240 250 351 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:32:24 2016 done: Fri Nov 4 10:32:25 2016 Total Scan time: 7.740 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]