Result of FASTA (omim) for
pF1KB8206
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8206, 269 aa
1>>>pF1KB8206 269 - 269 aa - 269 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8514+/-0.000269; mu= 5.3867+/- 0.017
mean_var=184.5065+/-38.093, 0's: 0 Z-trim(125.2): 6 B-trim: 64 in 1/57
Lambda= 0.094421
statistics sampled from 48453 (48460) to 48453 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.858), E-opt: 0.2 (0.568), width: 16
Scan time: 5.570
The best scores are: opt bits E(85289)
NP_036609 (OMIM: 606961) WW domain-binding protein ( 269) 1962 278.3 1e-74
NP_001077382 (OMIM: 611129) WW domain binding prot ( 363) 578 89.9 7.1e-18
NP_060257 (OMIM: 611129) WW domain binding protein ( 342) 570 88.8 1.4e-17
XP_011538215 (OMIM: 611129) PREDICTED: WW domain b ( 354) 569 88.7 1.6e-17
>>NP_036609 (OMIM: 606961) WW domain-binding protein 1 [ (269 aa)
initn: 1962 init1: 1962 opt: 1962 Z-score: 1462.5 bits: 278.3 E(85289): 1e-74
Smith-Waterman score: 1962; 100.0% identity (100.0% similar) in 269 aa overlap (1-269:1-269)
10 20 30 40 50 60
pF1KB8 MARASSGNGSEEAWGALRAPQQQLRELCPGVNNQPYLCESGHCCGETGCCTYYYELWWFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MARASSGNGSEEAWGALRAPQQQLRELCPGVNNQPYLCESGHCCGETGCCTYYYELWWFW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPFPTGSLLDLRFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPFPTGSLLDLRFLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TFKPPAYEDVVHRPGTPPPPYTVAPGRPLTASSEQTCCSSSSSCPAHFEGTNVEGVSSHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TFKPPAYEDVVHRPGTPPPPYTVAPGRPLTASSEQTCCSSSSSCPAHFEGTNVEGVSSHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SAPPHQEGEPGAGVTPASTPPSCRYRRLTGDSGIELCPCPASGEGEPVKEVRVSATLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SAPPHQEGEPGAGVTPASTPPSCRYRRLTGDSGIELCPCPASGEGEPVKEVRVSATLPDL
190 200 210 220 230 240
250 260
pF1KB8 EDYSPCALPPESVPQIFPMGLSSSEGDIP
:::::::::::::::::::::::::::::
NP_036 EDYSPCALPPESVPQIFPMGLSSSEGDIP
250 260
>>NP_001077382 (OMIM: 611129) WW domain binding protein (363 aa)
initn: 702 init1: 452 opt: 578 Z-score: 441.9 bits: 89.9 E(85289): 7.1e-18
Smith-Waterman score: 584; 37.8% identity (56.7% similar) in 270 aa overlap (18-230:25-289)
10 20 30 40 50
pF1KB8 MARASSGNGSEEAWGALRAPQQQLRELCPGVNNQPYLCESGHCCGETGCCTYY
:: : .: : :.::: :.:..:::::.. ::.::
NP_001 MERRRLLGGMALLLLQALPSPLSARAEPPQDKEACVGTNNQSYICDTGHCCGQSQCCNYY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 YELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPFPTGSL
::::::::.::..:..::::. .::::: ::: ::::.::::.::. : :. . .:
NP_001 YELWWFWLVWTIIIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREA-HNYSALP----
70 80 90 100 110
120 130 140
pF1KB8 LDLRFLSTFKPPAYEDVVHRPGTPPPPYT-----------------------VAPGR---
. .::: .. : ::.::.:: ::::::. . : :
NP_001 FYFRFLPNYLLPPYEEVVNRPPTPPPPYSAFQLQQQQLLPPQCGPAGGSPPGIDPTRGSQ
120 130 140 150 160 170
150 160 170 180 190
pF1KB8 -----PLTASSEQTCCSSS------SSCPAHFEGTNVEGVSSHQSAPPHQEGEPGA----
::. :... : :. :. .:.. :. :. : .:::
NP_001 GAQSSPLSEPSRSSTRPPSIADPDPSDLPVDRAATKAPGMEPSGSVAGLGELDPGAFLDK
180 190 200 210 220 230
200 210 220 230
pF1KB8 ----------------GVTPASTPPSCRYRRLTGDSGIELCPCPASGEGEPVKEVRVSAT
:. .. :.::.:::::::.: : . . . .::
NP_001 DAECREELLKDDSSEHGAPDSKEKTPGRHRRFTGDSGIEVCVCNRGHHDDDLKEFNTLID
240 250 260 270 280 290
240 250 260
pF1KB8 LPDLEDYSPCALPPESVPQIFPMGLSSSEGDIP
NP_001 DALDGPLDFCDSCHVRPPGDEEEGLCQSSEEQAREPGHPHLPRPPACLLLNTINEQDSPN
300 310 320 330 340 350
>>NP_060257 (OMIM: 611129) WW domain binding protein 1-l (342 aa)
initn: 665 init1: 415 opt: 570 Z-score: 436.3 bits: 88.8 E(85289): 1.4e-17
Smith-Waterman score: 576; 37.6% identity (57.1% similar) in 266 aa overlap (22-230:8-268)
10 20 30 40 50 60
pF1KB8 MARASSGNGSEEAWGALRAPQQQLRELCPGVNNQPYLCESGHCCGETGCCTYYYELWWFW
.: .: : :.::: :.:..:::::.. ::.:::::::::
NP_060 MPFLLGLRQDKEACVGTNNQSYICDTGHCCGQSQCCNYYYELWWFW
10 20 30 40
70 80 90 100 110 120
pF1KB8 LLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPFPTGSLLDLRFLS
:.::..:..::::. .::::: ::: ::::.::::.::. : :. . .: . .:::
NP_060 LVWTIIIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREA-HNYSALP----FYFRFLP
50 60 70 80 90 100
130 140
pF1KB8 TFKPPAYEDVVHRPGTPPPPYT-----------------------VAPGR--------PL
.. : ::.::.:: ::::::. . : : ::
NP_060 NYLLPPYEEVVNRPPTPPPPYSAFQLQQQQLLPPQCGPAGGSPPGIDPTRGSQGAQSSPL
110 120 130 140 150 160
150 160 170 180 190
pF1KB8 TASSEQTCCSSS------SSCPAHFEGTNVEGVSSHQSAPPHQEGEPGA-----------
. :... : :. :. .:.. :. :. : .:::
NP_060 SEPSRSSTRPPSIADPDPSDLPVDRAATKAPGMEPSGSVAGLGELDPGAFLDKDAECREE
170 180 190 200 210 220
200 210 220 230 240
pF1KB8 ---------GVTPASTPPSCRYRRLTGDSGIELCPCPASGEGEPVKEVRVSATLPDLEDY
:. .. :.::.:::::::.: : . . . .::
NP_060 LLKDDSSEHGAPDSKEKTPGRHRRFTGDSGIEVCVCNRGHHDDDLKEFNTLIDDALDGPL
230 240 250 260 270 280
250 260
pF1KB8 SPCALPPESVPQIFPMGLSSSEGDIP
NP_060 DFCDSCHVRPPGDEEEGLCQSSEEQAREPGHPHLPRPPACLLLNTINEQDSPNSQSSSSP
290 300 310 320 330 340
>>XP_011538215 (OMIM: 611129) PREDICTED: WW domain bindi (354 aa)
initn: 665 init1: 415 opt: 569 Z-score: 435.4 bits: 88.7 E(85289): 1.6e-17
Smith-Waterman score: 575; 37.5% identity (56.9% similar) in 267 aa overlap (21-230:19-280)
10 20 30 40 50 60
pF1KB8 MARASSGNGSEEAWGALRAPQQQLRELCPGVNNQPYLCESGHCCGETGCCTYYYELWWFW
:. .: : :.::: :.:..:::::.. ::.:::::::::
XP_011 MSYSSLYPLNPTQCLAQRQRPDKEACVGTNNQSYICDTGHCCGQSQCCNYYYELWWFW
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPFPTGSLLDLRFLS
:.::..:..::::. .::::: ::: ::::.::::.::. : :. . .: . .:::
XP_011 LVWTIIIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREA-HNYSALP----FYFRFLP
60 70 80 90 100 110
130 140
pF1KB8 TFKPPAYEDVVHRPGTPPPPYT-----------------------VAPGR--------PL
.. : ::.::.:: ::::::. . : : ::
XP_011 NYLLPPYEEVVNRPPTPPPPYSAFQLQQQQLLPPQCGPAGGSPPGIDPTRGSQGAQSSPL
120 130 140 150 160 170
150 160 170 180 190
pF1KB8 TASSEQTCCSSS------SSCPAHFEGTNVEGVSSHQSAPPHQEGEPGA-----------
. :... : :. :. .:.. :. :. : .:::
XP_011 SEPSRSSTRPPSIADPDPSDLPVDRAATKAPGMEPSGSVAGLGELDPGAFLDKDAECREE
180 190 200 210 220 230
200 210 220 230 240
pF1KB8 ---------GVTPASTPPSCRYRRLTGDSGIELCPCPASGEGEPVKEVRVSATLPDLEDY
:. .. :.::.:::::::.: : . . . .::
XP_011 LLKDDSSEHGAPDSKEKTPGRHRRFTGDSGIEVCVCNRGHHDDDLKEFNTLIDDALDGPL
240 250 260 270 280 290
250 260
pF1KB8 SPCALPPESVPQIFPMGLSSSEGDIP
XP_011 DFCDSCHVRPPGDEEEGLCQSSEEQAREPGHPHLPRPPACLLLNTINEQDSPNSQSSSSP
300 310 320 330 340 350
269 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:33:01 2016 done: Fri Nov 4 10:33:02 2016
Total Scan time: 5.570 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]