FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8212, 134 aa 1>>>pF1KB8212 134 - 134 aa - 134 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5557+/-0.000641; mu= 11.3463+/- 0.039 mean_var=79.9212+/-15.670, 0's: 0 Z-trim(112.3): 10 B-trim: 0 in 0/52 Lambda= 0.143464 statistics sampled from 13063 (13071) to 13063 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.402), width: 16 Scan time: 1.620 The best scores are: opt bits E(32554) CCDS4406.1 SNCB gene_id:6620|Hs108|chr5 ( 134) 846 183.4 3.6e-47 CCDS83048.1 SNCB gene_id:6620|Hs108|chr5 ( 120) 600 132.5 7e-32 CCDS3634.1 SNCA gene_id:6622|Hs108|chr4 ( 140) 459 103.3 4.8e-23 CCDS43252.1 SNCA gene_id:6622|Hs108|chr4 ( 112) 383 87.5 2.2e-18 CCDS7380.1 SNCG gene_id:6623|Hs108|chr10 ( 127) 342 79.1 8.7e-16 CCDS81483.1 SNCG gene_id:6623|Hs108|chr10 ( 126) 266 63.3 4.7e-11 >>CCDS4406.1 SNCB gene_id:6620|Hs108|chr5 (134 aa) initn: 846 init1: 846 opt: 846 Z-score: 960.3 bits: 183.4 E(32554): 3.6e-47 Smith-Waterman score: 846; 100.0% identity (100.0% similar) in 134 aa overlap (1-134:1-134) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EQASHLGGAVFSGAGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EQASHLGGAVFSGAGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYE 70 80 90 100 110 120 130 pF1KB8 DPPQEEYQEYEPEA :::::::::::::: CCDS44 DPPQEEYQEYEPEA 130 >>CCDS83048.1 SNCB gene_id:6620|Hs108|chr5 (120 aa) initn: 747 init1: 521 opt: 600 Z-score: 685.8 bits: 132.5 E(32554): 7e-32 Smith-Waterman score: 723; 89.6% identity (89.6% similar) in 134 aa overlap (1-134:1-120) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK :::::::::::::::::::::::::::::::::::::::: :::::: CCDS83 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYV--------------VAEKTK 10 20 30 40 70 80 90 100 110 120 pF1KB8 EQASHLGGAVFSGAGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 EQASHLGGAVFSGAGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYE 50 60 70 80 90 100 130 pF1KB8 DPPQEEYQEYEPEA :::::::::::::: CCDS83 DPPQEEYQEYEPEA 110 120 >>CCDS3634.1 SNCA gene_id:6622|Hs108|chr4 (140 aa) initn: 602 init1: 383 opt: 459 Z-score: 527.1 bits: 103.3 E(32554): 4.8e-23 Smith-Waterman score: 496; 61.6% identity (79.5% similar) in 146 aa overlap (1-134:1-140) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK ::::::::: ::::::::::::::::.::: :::::::::::::.::::.:::.:::::: CCDS36 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK 10 20 30 40 50 60 70 80 90 100 pF1KB8 EQASHLGGAVFSG-----------AGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIE ::....:::: .: ::.::::::.::.... : :: : .: ..: CCDS36 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLG---KNEE---GAPQEGILE 70 80 90 100 110 110 120 130 pF1KB8 PL-MEPEGESYEDPPQEEYQEYEPEA . ..:..:.:: : .: ::.::::: CCDS36 DMPVDPDNEAYEMPSEEGYQDYEPEA 120 130 140 >>CCDS43252.1 SNCA gene_id:6622|Hs108|chr4 (112 aa) initn: 518 init1: 383 opt: 383 Z-score: 443.5 bits: 87.5 E(32554): 2.2e-18 Smith-Waterman score: 412; 66.7% identity (81.1% similar) in 111 aa overlap (1-96:1-111) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK ::::::::: ::::::::::::::::.::: :::::::::::::.::::.:::.:::::: CCDS43 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK 10 20 30 40 50 60 70 80 90 100 pF1KB8 EQASHLGGAVFSG-----------AGNIAAATGLVKREEFPT----DLKPEEVAQEAAEE ::....:::: .: ::.::::::.::.... : .:: CCDS43 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKEGYQDYEPEA 70 80 90 100 110 110 120 130 pF1KB8 PLIEPLMEPEGESYEDPPQEEYQEYEPEA >>CCDS7380.1 SNCG gene_id:6623|Hs108|chr10 (127 aa) initn: 570 init1: 341 opt: 342 Z-score: 396.9 bits: 79.1 E(32554): 8.7e-16 Smith-Waterman score: 362; 54.5% identity (73.5% similar) in 132 aa overlap (1-121:1-127) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK :::: ::.:.::::::.:.::::::::::::::::::.:::.::.:.:::.:.::::::: CCDS73 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTK 10 20 30 40 50 60 70 80 90 100 pF1KB8 EQASHLGGAVFSG-----------AGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIE :::. .. :: :. : :::...:.:..: ::.: ::. : CCDS73 EQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKE----DLRPSAPQQEGEASKEKE 70 80 90 100 110 110 120 130 pF1KB8 PLMEPEGESYEDPPQEEYQEYEPEA . : :..: : CCDS73 EVAE-EAQSGGD 120 >>CCDS81483.1 SNCG gene_id:6623|Hs108|chr10 (126 aa) initn: 266 init1: 266 opt: 266 Z-score: 311.9 bits: 63.3 E(32554): 4.7e-11 Smith-Waterman score: 266; 79.6% identity (98.1% similar) in 54 aa overlap (1-54:1-54) 10 20 30 40 50 60 pF1KB8 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK :::: ::.:.::::::.:.::::::::::::::::::.:::.::.:.:::.:.: CCDS81 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSGLPWGW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EQASHLGGAVFSGAGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYE CCDS81 GWGGGQPVSSHSGREDQGAGQRRERGCGEQRQHCGHQDRGGGGEHRGHLRGGAQGGLEAI 70 80 90 100 110 120 134 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:37:16 2016 done: Fri Nov 4 10:37:16 2016 Total Scan time: 1.620 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]