FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8216, 215 aa 1>>>pF1KB8216 215 - 215 aa - 215 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7658+/-0.000348; mu= 9.0034+/- 0.022 mean_var=119.9176+/-23.718, 0's: 0 Z-trim(117.6): 30 B-trim: 533 in 1/53 Lambda= 0.117120 statistics sampled from 29725 (29755) to 29725 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.349), width: 16 Scan time: 5.140 The best scores are: opt bits E(85289) NP_001307122 (OMIM: 601234) nascent polypeptide-as ( 215) 1310 231.5 7.9e-61 NP_005585 (OMIM: 601234) nascent polypeptide-assoc ( 215) 1310 231.5 7.9e-61 NP_001106673 (OMIM: 601234) nascent polypeptide-as ( 215) 1310 231.5 7.9e-61 NP_001106672 (OMIM: 601234) nascent polypeptide-as ( 215) 1310 231.5 7.9e-61 NP_001307123 (OMIM: 601234) nascent polypeptide-as ( 219) 1287 227.7 1.2e-59 XP_006719483 (OMIM: 601234) PREDICTED: nascent pol ( 219) 1287 227.7 1.2e-59 XP_006719481 (OMIM: 601234) PREDICTED: nascent pol ( 219) 1287 227.7 1.2e-59 NP_954984 (OMIM: 609274) nascent polypeptide-assoc ( 215) 1177 209.1 4.6e-54 NP_001106674 (OMIM: 601234) nascent polypeptide-as ( 925) 1181 210.2 9.1e-54 XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 1181 210.4 1.7e-53 XP_016874826 (OMIM: 601234) PREDICTED: nascent pol ( 940) 1158 206.3 1.4e-52 XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 1158 206.5 2.6e-52 XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 1158 206.5 2.6e-52 XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 1158 206.5 2.6e-52 >>NP_001307122 (OMIM: 601234) nascent polypeptide-associ (215 aa) initn: 1310 init1: 1310 opt: 1310 Z-score: 1213.1 bits: 231.5 E(85289): 7.9e-61 Smith-Waterman score: 1310; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD 130 140 150 160 170 180 190 200 210 pF1KB8 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM ::::::::::::::::::::::::::::::::::: NP_001 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 190 200 210 >>NP_005585 (OMIM: 601234) nascent polypeptide-associate (215 aa) initn: 1310 init1: 1310 opt: 1310 Z-score: 1213.1 bits: 231.5 E(85289): 7.9e-61 Smith-Waterman score: 1310; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD 130 140 150 160 170 180 190 200 210 pF1KB8 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM ::::::::::::::::::::::::::::::::::: NP_005 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 190 200 210 >>NP_001106673 (OMIM: 601234) nascent polypeptide-associ (215 aa) initn: 1310 init1: 1310 opt: 1310 Z-score: 1213.1 bits: 231.5 E(85289): 7.9e-61 Smith-Waterman score: 1310; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD 130 140 150 160 170 180 190 200 210 pF1KB8 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM ::::::::::::::::::::::::::::::::::: NP_001 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 190 200 210 >>NP_001106672 (OMIM: 601234) nascent polypeptide-associ (215 aa) initn: 1310 init1: 1310 opt: 1310 Z-score: 1213.1 bits: 231.5 E(85289): 7.9e-61 Smith-Waterman score: 1310; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD 130 140 150 160 170 180 190 200 210 pF1KB8 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM ::::::::::::::::::::::::::::::::::: NP_001 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 190 200 210 >>NP_001307123 (OMIM: 601234) nascent polypeptide-associ (219 aa) initn: 1287 init1: 1287 opt: 1287 Z-score: 1192.0 bits: 227.7 E(85289): 1.2e-59 Smith-Waterman score: 1287; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211) 10 20 30 40 50 60 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD 130 140 150 160 170 180 190 200 210 pF1KB8 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM ::::::::::::::::::::::::::::::: NP_001 IELVMSQANVSRAKAVRALKNNSNDIVNAIMVSVQAFVP 190 200 210 >>XP_006719483 (OMIM: 601234) PREDICTED: nascent polypep (219 aa) initn: 1287 init1: 1287 opt: 1287 Z-score: 1192.0 bits: 227.7 E(85289): 1.2e-59 Smith-Waterman score: 1287; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211) 10 20 30 40 50 60 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD 130 140 150 160 170 180 190 200 210 pF1KB8 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM ::::::::::::::::::::::::::::::: XP_006 IELVMSQANVSRAKAVRALKNNSNDIVNAIMVSVQAFVP 190 200 210 >>XP_006719481 (OMIM: 601234) PREDICTED: nascent polypep (219 aa) initn: 1287 init1: 1287 opt: 1287 Z-score: 1192.0 bits: 227.7 E(85289): 1.2e-59 Smith-Waterman score: 1287; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211) 10 20 30 40 50 60 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD 130 140 150 160 170 180 190 200 210 pF1KB8 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM ::::::::::::::::::::::::::::::: XP_006 IELVMSQANVSRAKAVRALKNNSNDIVNAIMVSVQAFVP 190 200 210 >>NP_954984 (OMIM: 609274) nascent polypeptide-associate (215 aa) initn: 1240 init1: 1177 opt: 1177 Z-score: 1091.6 bits: 209.1 E(85289): 4.6e-54 Smith-Waterman score: 1177; 90.2% identity (96.3% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEID :::::::::::::::::: :::::::: ::: :::: .:::::::.:::.: :.:::::: NP_954 MPGEATETVPATEQELPQSQAETGSGTASDSGESVPGIEEQDSTQTTTQKAWLVAAAEID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTY ::::.:::::::::.:::::::::: :::::::::: ::::::::::: :::::::::.: NP_954 EEPVGKAKQSRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD ::::::::.::::::::::::::.::::::.::::::::::::::::::::::::::::: NP_954 IVFGEAKIQDLSQQAQLAAAEKFRVQGEAVGNIQENTQTPTVQEESEEEEVDETGVEVKD 130 140 150 160 170 180 190 200 210 pF1KB8 IELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM ..::::::::::::::::::::::::::::::::. NP_954 VKLVMSQANVSRAKAVRALKNNSNDIVNAIMELTV 190 200 210 >>NP_001106674 (OMIM: 601234) nascent polypeptide-associ (925 aa) initn: 1176 init1: 1176 opt: 1181 Z-score: 1086.3 bits: 210.2 E(85289): 9.1e-54 Smith-Waterman score: 1181; 92.1% identity (93.9% similar) in 214 aa overlap (2-215:712-925) 10 20 30 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDS : : ::. . : . . :::::::: NP_001 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 690 700 710 720 730 740 40 50 60 70 80 90 pF1KB8 DESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGV 750 760 770 780 790 800 100 110 120 130 140 150 pF1KB8 TRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVS 810 820 830 840 850 860 160 170 180 190 200 210 pF1KB8 NIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIM 870 880 890 900 910 920 pF1KB8 ELTM :::: NP_001 ELTM >>XP_011536691 (OMIM: 601234) PREDICTED: nascent polypep (2078 aa) initn: 1176 init1: 1176 opt: 1181 Z-score: 1081.3 bits: 210.4 E(85289): 1.7e-53 Smith-Waterman score: 1181; 92.1% identity (93.9% similar) in 214 aa overlap (2-215:1865-2078) 10 20 30 pF1KB8 MPGEATETVPATEQELPQPQAETGSGTESDS : : ::. . : . . :::::::: XP_011 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1840 1850 1860 1870 1880 1890 40 50 60 70 80 90 pF1KB8 DESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGV 1900 1910 1920 1930 1940 1950 100 110 120 130 140 150 pF1KB8 TRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVS 1960 1970 1980 1990 2000 2010 160 170 180 190 200 210 pF1KB8 NIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIM 2020 2030 2040 2050 2060 2070 pF1KB8 ELTM :::: XP_011 ELTM 215 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:38:59 2016 done: Fri Nov 4 10:39:00 2016 Total Scan time: 5.140 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]