FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8221, 248 aa 1>>>pF1KB8221 248 - 248 aa - 248 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1520+/-0.000723; mu= 8.7706+/- 0.044 mean_var=153.1611+/-30.873, 0's: 0 Z-trim(114.9): 8 B-trim: 157 in 1/52 Lambda= 0.103633 statistics sampled from 15462 (15470) to 15462 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.475), width: 16 Scan time: 2.510 The best scores are: opt bits E(32554) CCDS6601.1 CLTA gene_id:1211|Hs108|chr9 ( 248) 1675 261.0 5.3e-70 CCDS43802.1 CLTA gene_id:1211|Hs108|chr9 ( 236) 1221 193.1 1.4e-49 CCDS6600.1 CLTA gene_id:1211|Hs108|chr9 ( 218) 1127 179.1 2.2e-45 CCDS55306.1 CLTA gene_id:1211|Hs108|chr9 ( 230) 1094 174.1 7e-44 CCDS83364.1 CLTA gene_id:1211|Hs108|chr9 ( 196) 833 135.1 3.5e-32 CCDS4403.1 CLTB gene_id:1212|Hs108|chr5 ( 229) 648 107.5 8.3e-24 CCDS4402.1 CLTB gene_id:1212|Hs108|chr5 ( 211) 581 97.4 8.1e-21 CCDS55307.1 CLTA gene_id:1211|Hs108|chr9 ( 166) 532 90.0 1.1e-18 >>CCDS6601.1 CLTA gene_id:1211|Hs108|chr9 (248 aa) initn: 1675 init1: 1675 opt: 1675 Z-score: 1370.3 bits: 261.0 E(32554): 5.3e-70 Smith-Waterman score: 1675; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248) 10 20 30 40 50 60 pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS 190 200 210 220 230 240 pF1KB8 LKQAPLVH :::::::: CCDS66 LKQAPLVH >>CCDS43802.1 CLTA gene_id:1211|Hs108|chr9 (236 aa) initn: 1573 init1: 1221 opt: 1221 Z-score: 1003.7 bits: 193.1 E(32554): 1.4e-49 Smith-Waterman score: 1553; 95.2% identity (95.2% similar) in 248 aa overlap (1-248:1-236) 10 20 30 40 50 60 pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS :::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS 190 200 210 220 pF1KB8 LKQAPLVH :::::::: CCDS43 LKQAPLVH 230 >>CCDS6600.1 CLTA gene_id:1211|Hs108|chr9 (218 aa) initn: 1127 init1: 1127 opt: 1127 Z-score: 928.2 bits: 179.1 E(32554): 2.2e-45 Smith-Waterman score: 1397; 87.9% identity (87.9% similar) in 248 aa overlap (1-248:1-218) 10 20 30 40 50 60 pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV :::::::::::::::::::::::::::::::::::::::::: CCDS66 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNR------------------ 130 140 150 160 190 200 210 220 230 240 pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS :::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 ------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS 170 180 190 200 210 pF1KB8 LKQAPLVH :::::::: CCDS66 LKQAPLVH >>CCDS55306.1 CLTA gene_id:1211|Hs108|chr9 (230 aa) initn: 1534 init1: 1094 opt: 1094 Z-score: 901.3 bits: 174.1 E(32554): 7e-44 Smith-Waterman score: 1501; 92.3% identity (92.3% similar) in 248 aa overlap (1-248:1-230) 10 20 30 40 50 60 pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV ::::::::::::::::::::::::::::::::::::::::: CCDS55 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNS------------------ 130 140 150 160 190 200 210 220 230 240 pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS 170 180 190 200 210 220 pF1KB8 LKQAPLVH :::::::: CCDS55 LKQAPLVH 230 >>CCDS83364.1 CLTA gene_id:1211|Hs108|chr9 (196 aa) initn: 826 init1: 826 opt: 833 Z-score: 691.3 bits: 135.1 E(32554): 3.5e-32 Smith-Waterman score: 1218; 79.0% identity (79.0% similar) in 248 aa overlap (1-248:1-196) 10 20 30 40 50 60 pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER :::::::::::: CCDS83 GPQPHGEPPGGP------------------------------------------------ 70 130 140 150 160 170 180 pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 ----DANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV 80 90 100 110 120 190 200 210 220 230 240 pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS 130 140 150 160 170 180 pF1KB8 LKQAPLVH :::::::: CCDS83 LKQAPLVH 190 >>CCDS4403.1 CLTB gene_id:1212|Hs108|chr5 (229 aa) initn: 677 init1: 490 opt: 648 Z-score: 540.9 bits: 107.5 E(32554): 8.3e-24 Smith-Waterman score: 893; 61.2% identity (79.3% similar) in 227 aa overlap (21-246:13-227) 10 20 30 40 50 60 pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP .:. :.:::::::::::::::::::::::.:. :. CCDS44 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA 10 20 30 40 50 70 80 90 100 110 pF1KB8 GPQPHGEPPG-GPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME .: : : : . . ..::. .::.:::.:.::::.:.::: .:::::::::::: . CCDS44 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGY ::. ::: :. : ::.::: :.:::: ::.::..:.: :::.::.:::.:: ::.::: CCDS44 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 VTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLI : :.:::::.. : .::::::.::.::::::::::: :::::.::::. CCDS44 V------------ASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM 180 190 200 210 220 240 pF1KB8 SLKQAPLVH ::::.:: CCDS44 SLKQTPLSR >>CCDS4402.1 CLTB gene_id:1212|Hs108|chr5 (211 aa) initn: 625 init1: 422 opt: 581 Z-score: 487.2 bits: 97.4 E(32554): 8.1e-21 Smith-Waterman score: 761; 55.5% identity (71.8% similar) in 227 aa overlap (21-246:13-209) 10 20 30 40 50 60 pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP .:. :.:::::::::::::::::::::::.:. :. CCDS44 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA 10 20 30 40 50 70 80 90 100 110 pF1KB8 GPQPHGEPPG-GPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME .: : : : . . ..::. .::.:::.:.::::.:.::: .:::::::::::: . CCDS44 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGY ::. ::: :. : ::.::: :.:::: ::.::..:.: ::: CCDS44 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR----------------- 120 130 140 150 180 190 200 210 220 230 pF1KB8 VTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLI :.:::::.. : .::::::.::.::::::::::: :::::.::::. CCDS44 -------------ASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM 160 170 180 190 200 240 pF1KB8 SLKQAPLVH ::::.:: CCDS44 SLKQTPLSR 210 >>CCDS55307.1 CLTA gene_id:1211|Hs108|chr9 (166 aa) initn: 872 init1: 519 opt: 532 Z-score: 449.0 bits: 90.0 E(32554): 1.1e-18 Smith-Waterman score: 940; 66.9% identity (66.9% similar) in 248 aa overlap (1-248:1-166) 10 20 30 40 50 60 pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER :::::::::::: CCDS55 GPQPHGEPPGGP------------------------------------------------ 70 130 140 150 160 170 180 pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV :::::::::::::::::::::::::::::::::::::: CCDS55 ----DANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNR------------------ 80 90 100 110 190 200 210 220 230 240 pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS :::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS 120 130 140 150 pF1KB8 LKQAPLVH :::::::: CCDS55 LKQAPLVH 160 248 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:41:44 2016 done: Fri Nov 4 10:41:44 2016 Total Scan time: 2.510 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]