FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8223, 272 aa 1>>>pF1KB8223 272 - 272 aa - 272 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7039+/-0.00102; mu= 12.7874+/- 0.061 mean_var=65.2685+/-12.670, 0's: 0 Z-trim(103.1): 16 B-trim: 8 in 1/48 Lambda= 0.158753 statistics sampled from 7256 (7262) to 7256 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.223), width: 16 Scan time: 2.000 The best scores are: opt bits E(32554) CCDS11548.1 PHB gene_id:5245|Hs108|chr17 ( 272) 1701 398.5 2.6e-111 CCDS62244.1 PHB gene_id:5245|Hs108|chr17 ( 155) 911 217.5 4.6e-57 CCDS53741.1 PHB2 gene_id:11331|Hs108|chr12 ( 299) 862 206.4 2e-53 CCDS58207.1 PHB2 gene_id:11331|Hs108|chr12 ( 261) 661 160.3 1.3e-39 >>CCDS11548.1 PHB gene_id:5245|Hs108|chr17 (272 aa) initn: 1701 init1: 1701 opt: 1701 Z-score: 2111.8 bits: 398.5 E(32554): 2.6e-111 Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272) 10 20 30 40 50 60 pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK 190 200 210 220 230 240 250 260 270 pF1KB8 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ :::::::::::::::::::::::::::::::: CCDS11 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ 250 260 270 >>CCDS62244.1 PHB gene_id:5245|Hs108|chr17 (155 aa) initn: 911 init1: 911 opt: 911 Z-score: 1137.9 bits: 217.5 E(32554): 4.6e-57 Smith-Waterman score: 911; 100.0% identity (100.0% similar) in 141 aa overlap (1-141:1-141) 10 20 30 40 50 60 pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT ::::::::::::::::::::: CCDS62 SITTEILKSVVARFDAGELITYLPAGQSVLLQLPQ 130 140 150 >>CCDS53741.1 PHB2 gene_id:11331|Hs108|chr12 (299 aa) initn: 784 init1: 715 opt: 862 Z-score: 1072.6 bits: 206.4 E(32554): 2e-53 Smith-Waterman score: 862; 53.9% identity (82.3% similar) in 254 aa overlap (15-267:29-280) 10 20 30 40 pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ : ::: :: .: ...:..::::..:.:. ::: CCDS53 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR : ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..:: CCDS53 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL .. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.::: CCDS53 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIA :::..:.:.:..:.: ::::::::::::.::.:.::::.:... :..:::...::.... CCDS53 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG 180 190 200 210 220 230 230 240 250 260 270 pF1KB8 NSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ ..: . . : :.:::..::..:. .. :.: :: : . :: CCDS53 EAL-SKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 240 250 260 270 280 290 CCDS53 K >>CCDS58207.1 PHB2 gene_id:11331|Hs108|chr12 (261 aa) initn: 645 init1: 576 opt: 661 Z-score: 824.8 bits: 160.3 E(32554): 1.3e-39 Smith-Waterman score: 661; 48.3% identity (76.5% similar) in 234 aa overlap (15-240:29-261) 10 20 30 40 pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ : ::: :: .: ...:..::::..:.:. ::: CCDS58 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR : ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..:: CCDS58 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL .. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.::: CCDS58 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL 120 130 140 150 160 170 170 180 190 200 210 pF1KB8 DDVSLTHLTFGKEFTEAVEAKQVA-QQEAERARFVVEKAEQQKKAAIISAEG------DS :::..:.:.:..:.: :::::::: ... .. .: :. . .: .... :. CCDS58 DDVAITELSFSREYTAAVEAKQVALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADN 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB8 KAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ . .: .:.. ..:.::. .: CCDS58 LVLNLQDESFTRGSDSLIKGKK 240 250 260 272 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:42:24 2016 done: Fri Nov 4 10:42:24 2016 Total Scan time: 2.000 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]