FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8223, 272 aa
1>>>pF1KB8223 272 - 272 aa - 272 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7039+/-0.00102; mu= 12.7874+/- 0.061
mean_var=65.2685+/-12.670, 0's: 0 Z-trim(103.1): 16 B-trim: 8 in 1/48
Lambda= 0.158753
statistics sampled from 7256 (7262) to 7256 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.223), width: 16
Scan time: 2.000
The best scores are: opt bits E(32554)
CCDS11548.1 PHB gene_id:5245|Hs108|chr17 ( 272) 1701 398.5 2.6e-111
CCDS62244.1 PHB gene_id:5245|Hs108|chr17 ( 155) 911 217.5 4.6e-57
CCDS53741.1 PHB2 gene_id:11331|Hs108|chr12 ( 299) 862 206.4 2e-53
CCDS58207.1 PHB2 gene_id:11331|Hs108|chr12 ( 261) 661 160.3 1.3e-39
>>CCDS11548.1 PHB gene_id:5245|Hs108|chr17 (272 aa)
initn: 1701 init1: 1701 opt: 1701 Z-score: 2111.8 bits: 398.5 E(32554): 2.6e-111
Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
190 200 210 220 230 240
250 260 270
pF1KB8 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
::::::::::::::::::::::::::::::::
CCDS11 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
250 260 270
>>CCDS62244.1 PHB gene_id:5245|Hs108|chr17 (155 aa)
initn: 911 init1: 911 opt: 911 Z-score: 1137.9 bits: 217.5 E(32554): 4.6e-57
Smith-Waterman score: 911; 100.0% identity (100.0% similar) in 141 aa overlap (1-141:1-141)
10 20 30 40 50 60
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
:::::::::::::::::::::
CCDS62 SITTEILKSVVARFDAGELITYLPAGQSVLLQLPQ
130 140 150
>>CCDS53741.1 PHB2 gene_id:11331|Hs108|chr12 (299 aa)
initn: 784 init1: 715 opt: 862 Z-score: 1072.6 bits: 206.4 E(32554): 2e-53
Smith-Waterman score: 862; 53.9% identity (82.3% similar) in 254 aa overlap (15-267:29-280)
10 20 30 40
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
: ::: :: .: ...:..::::..:.:. :::
CCDS53 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
CCDS53 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
CCDS53 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIA
:::..:.:.:..:.: ::::::::::::.::.:.::::.:... :..:::...::....
CCDS53 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 NSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
..: . . : :.:::..::..:. .. :.: :: : . ::
CCDS53 EAL-SKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK
240 250 260 270 280 290
CCDS53 K
>>CCDS58207.1 PHB2 gene_id:11331|Hs108|chr12 (261 aa)
initn: 645 init1: 576 opt: 661 Z-score: 824.8 bits: 160.3 E(32554): 1.3e-39
Smith-Waterman score: 661; 48.3% identity (76.5% similar) in 234 aa overlap (15-240:29-261)
10 20 30 40
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
: ::: :: .: ...:..::::..:.:. :::
CCDS58 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
CCDS58 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
CCDS58 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 DDVSLTHLTFGKEFTEAVEAKQVA-QQEAERARFVVEKAEQQKKAAIISAEG------DS
:::..:.:.:..:.: :::::::: ... .. .: :. . .: .... :.
CCDS58 DDVAITELSFSREYTAAVEAKQVALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADN
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 KAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
. .: .:.. ..:.::. .:
CCDS58 LVLNLQDESFTRGSDSLIKGKK
240 250 260
272 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:42:24 2016 done: Fri Nov 4 10:42:24 2016
Total Scan time: 2.000 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]