Result of FASTA (omim) for
pF1KB8223
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8223, 272 aa
1>>>pF1KB8223 272 - 272 aa - 272 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8763+/-0.000428; mu= 11.9156+/- 0.027
mean_var=69.4534+/-13.456, 0's: 0 Z-trim(110.2): 26 B-trim: 35 in 1/56
Lambda= 0.153896
statistics sampled from 18466 (18486) to 18466 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.581), E-opt: 0.2 (0.217), width: 16
Scan time: 5.690
The best scores are: opt bits E(85289)
NP_001268644 (OMIM: 114480,176705) prohibitin isof ( 272) 1701 386.9 2.1e-107
XP_016880252 (OMIM: 114480,176705) PREDICTED: proh ( 272) 1701 386.9 2.1e-107
NP_001268425 (OMIM: 114480,176705) prohibitin isof ( 272) 1701 386.9 2.1e-107
NP_002625 (OMIM: 114480,176705) prohibitin isoform ( 272) 1701 386.9 2.1e-107
XP_016880251 (OMIM: 114480,176705) PREDICTED: proh ( 289) 1282 293.9 2.3e-79
NP_001268426 (OMIM: 114480,176705) prohibitin isof ( 155) 911 211.4 8e-55
NP_001138303 (OMIM: 610704) prohibitin-2 isoform 1 ( 299) 862 200.7 2.7e-51
NP_001254629 (OMIM: 610704) prohibitin-2 isoform 3 ( 261) 661 156.0 6.6e-38
>>NP_001268644 (OMIM: 114480,176705) prohibitin isoform (272 aa)
initn: 1701 init1: 1701 opt: 1701 Z-score: 2049.2 bits: 386.9 E(85289): 2.1e-107
Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
190 200 210 220 230 240
250 260 270
pF1KB8 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
::::::::::::::::::::::::::::::::
NP_001 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
250 260 270
>>XP_016880252 (OMIM: 114480,176705) PREDICTED: prohibit (272 aa)
initn: 1701 init1: 1701 opt: 1701 Z-score: 2049.2 bits: 386.9 E(85289): 2.1e-107
Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
190 200 210 220 230 240
250 260 270
pF1KB8 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
::::::::::::::::::::::::::::::::
XP_016 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
250 260 270
>>NP_001268425 (OMIM: 114480,176705) prohibitin isoform (272 aa)
initn: 1701 init1: 1701 opt: 1701 Z-score: 2049.2 bits: 386.9 E(85289): 2.1e-107
Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
190 200 210 220 230 240
250 260 270
pF1KB8 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
::::::::::::::::::::::::::::::::
NP_001 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
250 260 270
>>NP_002625 (OMIM: 114480,176705) prohibitin isoform 1 [ (272 aa)
initn: 1701 init1: 1701 opt: 1701 Z-score: 2049.2 bits: 386.9 E(85289): 2.1e-107
Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
190 200 210 220 230 240
250 260 270
pF1KB8 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
::::::::::::::::::::::::::::::::
NP_002 LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
250 260 270
>>XP_016880251 (OMIM: 114480,176705) PREDICTED: prohibit (289 aa)
initn: 1282 init1: 1282 opt: 1282 Z-score: 1546.0 bits: 293.9 E(85289): 2.3e-79
Smith-Waterman score: 1282; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
::::::::::::::::::::::
XP_016 EAVEAKQVAQQEAERARFVVEKVSLRPDGRSLSLPFLRHSASPFAGWPGNSSSVIPSSGI
190 200 210 220 230 240
>>NP_001268426 (OMIM: 114480,176705) prohibitin isoform (155 aa)
initn: 911 init1: 911 opt: 911 Z-score: 1105.2 bits: 211.4 E(85289): 8e-55
Smith-Waterman score: 911; 100.0% identity (100.0% similar) in 141 aa overlap (1-141:1-141)
10 20 30 40 50 60
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
:::::::::::::::::::::
NP_001 SITTEILKSVVARFDAGELITYLPAGQSVLLQLPQ
130 140 150
>>NP_001138303 (OMIM: 610704) prohibitin-2 isoform 1 [Ho (299 aa)
initn: 784 init1: 715 opt: 862 Z-score: 1041.8 bits: 200.7 E(85289): 2.7e-51
Smith-Waterman score: 862; 53.9% identity (82.3% similar) in 254 aa overlap (15-267:29-280)
10 20 30 40
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
: ::: :: .: ...:..::::..:.:. :::
NP_001 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
NP_001 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
NP_001 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIA
:::..:.:.:..:.: ::::::::::::.::.:.::::.:... :..:::...::....
NP_001 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 NSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
..: . . : :.:::..::..:. .. :.: :: : . ::
NP_001 EAL-SKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK
240 250 260 270 280 290
NP_001 K
>>NP_001254629 (OMIM: 610704) prohibitin-2 isoform 3 [Ho (261 aa)
initn: 645 init1: 576 opt: 661 Z-score: 801.5 bits: 156.0 E(85289): 6.6e-38
Smith-Waterman score: 661; 48.3% identity (76.5% similar) in 234 aa overlap (15-240:29-261)
10 20 30 40
pF1KB8 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
: ::: :: .: ...:..::::..:.:. :::
NP_001 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
NP_001 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
NP_001 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 DDVSLTHLTFGKEFTEAVEAKQVA-QQEAERARFVVEKAEQQKKAAIISAEG------DS
:::..:.:.:..:.: :::::::: ... .. .: :. . .: .... :.
NP_001 DDVAITELSFSREYTAAVEAKQVALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADN
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 KAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
. .: .:.. ..:.::. .:
NP_001 LVLNLQDESFTRGSDSLIKGKK
240 250 260
272 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:42:25 2016 done: Fri Nov 4 10:42:26 2016
Total Scan time: 5.690 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]