FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8224, 253 aa
  1>>>pF1KB8224 253 - 253 aa - 253 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2573+/-0.000299; mu= -1.0895+/- 0.019
 mean_var=226.2568+/-44.527, 0's: 0 Z-trim(125.2): 3  B-trim: 408 in 1/57
 Lambda= 0.085266
 statistics sampled from 48325 (48328) to 48325 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.837), E-opt: 0.2 (0.567), width:  16
 Scan time:  7.240

The best scores are:                                      opt bits E(85289)
NP_037474 (OMIM: 609519) TCF3 fusion partner isofo ( 253) 1702 220.8 1.8e-57
NP_001308721 (OMIM: 609519) TCF3 fusion partner is ( 244) 1645 213.8 2.3e-55
XP_005278318 (OMIM: 609519) PREDICTED: TCF3 fusion ( 133)  917 124.1 1.3e-28


>>NP_037474 (OMIM: 609519) TCF3 fusion partner isoform 1  (253 aa)
 initn: 1702 init1: 1702 opt: 1702  Z-score: 1152.6  bits: 220.8 E(85289): 1.8e-57
Smith-Waterman score: 1702; 100.0% identity (100.0% similar) in 253 aa overlap (1-253:1-253)

               10        20        30        40        50        60
pF1KB8 MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRER
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 MRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDK
              190       200       210       220       230       240

              250   
pF1KB8 LLPYPTLASPASD
       :::::::::::::
NP_037 LLPYPTLASPASD
              250   

>>NP_001308721 (OMIM: 609519) TCF3 fusion partner isofor  (244 aa)
 initn: 1645 init1: 1645 opt: 1645  Z-score: 1114.9  bits: 213.8 E(85289): 2.3e-55
Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 244 aa overlap (10-253:1-244)

               10        20        30        40        50        60
pF1KB8 MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRER
                :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001          MAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRER
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KB8 DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KB8 MRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGS
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KB8 PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDK
             180       190       200       210       220       230 

              250   
pF1KB8 LLPYPTLASPASD
       :::::::::::::
NP_001 LLPYPTLASPASD
             240    

>>XP_005278318 (OMIM: 609519) PREDICTED: TCF3 fusion par  (133 aa)
 initn: 917 init1: 917 opt: 917  Z-score: 634.7  bits: 124.1 E(85289): 1.3e-28
Smith-Waterman score: 917; 100.0% identity (100.0% similar) in 133 aa overlap (121-253:1-133)

              100       110       120       130       140       150
pF1KB8 EIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDA
                                     ::::::::::::::::::::::::::::::
XP_005                               MRVLDSYGDDYRASQFTIVLEDEGSQGTDA
                                             10        20        30

              160       170       180       190       200       210
pF1KB8 PTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPEL
               40        50        60        70        80        90

              220       230       240       250   
pF1KB8 APVQIKVEEDFGFEADEALDSSWVSRGPDKLLPYPTLASPASD
       :::::::::::::::::::::::::::::::::::::::::::
XP_005 APVQIKVEEDFGFEADEALDSSWVSRGPDKLLPYPTLASPASD
              100       110       120       130   




253 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:43:12 2016 done: Fri Nov  4 10:43:13 2016
 Total Scan time:  7.240 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]