FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8227, 185 aa 1>>>pF1KB8227 185 - 185 aa - 185 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5687+/-0.000282; mu= -0.0231+/- 0.018 mean_var=200.4596+/-41.084, 0's: 0 Z-trim(124.4): 18 B-trim: 0 in 0/59 Lambda= 0.090586 statistics sampled from 46042 (46060) to 46042 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.839), E-opt: 0.2 (0.54), width: 16 Scan time: 5.620 The best scores are: opt bits E(85289) NP_002405 (OMIM: 313470,450000) CD99 antigen isofo ( 185) 1248 174.0 1.2e-43 NP_001308297 (OMIM: 313470,450000) CD99 antigen is ( 184) 1231 171.8 5.5e-43 NP_001308296 (OMIM: 313470,450000) CD99 antigen is ( 160) 1077 151.6 5.7e-37 NP_001116370 (OMIM: 313470,450000) CD99 antigen is ( 169) 937 133.4 1.9e-31 NP_001308298 (OMIM: 313470,450000) CD99 antigen is ( 168) 920 131.1 8.8e-31 NP_001308299 (OMIM: 313470,450000) CD99 antigen is ( 168) 715 104.4 1e-22 NP_604395 (OMIM: 300846) CD99 antigen-like protein ( 213) 264 45.5 6.8e-05 NP_113650 (OMIM: 300846) CD99 antigen-like protein ( 262) 261 45.2 0.0001 XP_016885380 (OMIM: 300846) PREDICTED: CD99 antige ( 218) 255 44.3 0.00016 NP_001229543 (OMIM: 300846) CD99 antigen-like prot ( 272) 254 44.3 0.0002 XP_016885379 (OMIM: 300846) PREDICTED: CD99 antige ( 267) 252 44.0 0.00024 NP_604394 (OMIM: 300846) CD99 antigen-like protein ( 190) 249 43.5 0.00024 >>NP_002405 (OMIM: 313470,450000) CD99 antigen isoform a (185 aa) initn: 1248 init1: 1248 opt: 1248 Z-score: 904.7 bits: 174.0 E(85289): 1.2e-43 Smith-Waterman score: 1248; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185) 10 20 30 40 50 60 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR 130 140 150 160 170 180 pF1KB8 TLLEK ::::: NP_002 TLLEK >>NP_001308297 (OMIM: 313470,450000) CD99 antigen isofor (184 aa) initn: 1232 init1: 1078 opt: 1231 Z-score: 892.7 bits: 171.8 E(85289): 5.5e-43 Smith-Waterman score: 1231; 99.5% identity (99.5% similar) in 185 aa overlap (1-185:1-184) 10 20 30 40 50 60 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR :::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_001 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKEN-EQGEVDMESHRNANAEPAVQR 130 140 150 160 170 pF1KB8 TLLEK ::::: NP_001 TLLEK 180 >>NP_001308296 (OMIM: 313470,450000) CD99 antigen isofor (160 aa) initn: 1077 init1: 1077 opt: 1077 Z-score: 784.8 bits: 151.6 E(85289): 5.7e-37 Smith-Waterman score: 1077; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR :::::::::::::::::::::::::::::::::::::: NP_001 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENDG 130 140 150 160 pF1KB8 TLLEK >>NP_001116370 (OMIM: 313470,450000) CD99 antigen isofor (169 aa) initn: 932 init1: 932 opt: 937 Z-score: 685.6 bits: 133.4 E(85289): 1.9e-31 Smith-Waterman score: 1099; 91.4% identity (91.4% similar) in 185 aa overlap (1-185:1-169) 10 20 30 40 50 60 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV ::::::::::::::::::::::::::::::::: ::::::::::: NP_001 MARGAALALLLFGLLGVLVAAPDGGFDLSDALP----------------GDDFDLGDAVV 10 20 30 40 70 80 90 100 110 120 pF1KB8 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR 110 120 130 140 150 160 pF1KB8 TLLEK ::::: NP_001 TLLEK >>NP_001308298 (OMIM: 313470,450000) CD99 antigen isofor (168 aa) initn: 1157 init1: 762 opt: 920 Z-score: 673.6 bits: 131.1 E(85289): 8.8e-31 Smith-Waterman score: 1082; 90.8% identity (90.8% similar) in 185 aa overlap (1-185:1-168) 10 20 30 40 50 60 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV ::::::::::::::::::::::::::::::::: ::::::::::: NP_001 MARGAALALLLFGLLGVLVAAPDGGFDLSDALP----------------GDDFDLGDAVV 10 20 30 40 70 80 90 100 110 120 pF1KB8 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR :::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_001 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKEN-EQGEVDMESHRNANAEPAVQR 110 120 130 140 150 160 pF1KB8 TLLEK ::::: NP_001 TLLEK >>NP_001308299 (OMIM: 313470,450000) CD99 antigen isofor (168 aa) initn: 715 init1: 715 opt: 715 Z-score: 528.8 bits: 104.4 E(85289): 1e-22 Smith-Waterman score: 1083; 90.8% identity (90.8% similar) in 185 aa overlap (1-185:1-168) 10 20 30 40 50 60 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE ::::::::::::::::::::::::::::::::::::::::::: NP_001 DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGE----------------- 70 80 90 100 130 140 150 160 170 180 pF1KB8 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR 110 120 130 140 150 160 pF1KB8 TLLEK ::::: NP_001 TLLEK >>NP_604395 (OMIM: 300846) CD99 antigen-like protein 2 i (213 aa) initn: 191 init1: 145 opt: 264 Z-score: 208.8 bits: 45.5 E(85289): 6.8e-05 Smith-Waterman score: 282; 36.7% identity (60.4% similar) in 207 aa overlap (3-183:5-197) 10 20 30 40 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFD---LSDALPDNENKKP-----TAIPKKP--- :.: :. : :.: ..:: .: :: : ::. .. . : :. :.: NP_604 MVAWRSAFLVCLAFSL-ATLVQRGSGDFDDFNLEDAVKETSSVKQRWNHVTTTTKRPVTT 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 -----SAGDDFDLGDAVVDGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGG . :.::::.::. : .:: : . ::. ...:.::: :: : :.:: NP_604 RAPANTLGNDFDLADAL-DDRND--RDDGRRKPI--------AGGGGFSDKDLEDIVGGG 60 70 80 90 100 110 120 130 140 150 pF1KB8 E---GKGGSDGG-GSHRKEGEEADA-PGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKE : :: .:: ::. : : ::.: :...:...:. ::.::.:.::.::.:: NP_604 EYKPDKGKGDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCF-- 110 120 130 140 150 160 160 170 180 pF1KB8 NAEQG-EVDMESHRNANA----EPAVQRTLLEK . .:: ..:. . .: .: :: :. . : NP_604 SIQQGLNADYVKGENLEAVVCEEPQVKYSTLHTQSAEPPPPPEPARI 170 180 190 200 210 >>NP_113650 (OMIM: 300846) CD99 antigen-like protein 2 i (262 aa) initn: 231 init1: 145 opt: 261 Z-score: 205.5 bits: 45.2 E(85289): 0.0001 Smith-Waterman score: 287; 36.8% identity (60.6% similar) in 193 aa overlap (22-183:67-246) 10 20 30 40 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNEN--KKP--------- : .:.::.::: :... .:: NP_113 KETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWN 40 50 60 70 80 90 50 60 70 80 90 pF1KB8 --TAIPKKP--------SAGDDFDLGDAVVDGENDDPRPPNPPKPMPNPNPNHPSSSGSF :. :.: . :.::::.::. : .:: : . ::. ...:.: NP_113 HVTTTTKRPVTTRAPANTLGNDFDLADAL-DDRND--RDDGRRKPI--------AGGGGF 100 110 120 130 140 100 110 120 130 140 pF1KB8 SDADLADGVSGGE---GKGGSDGG-GSHRKEGEEADA-PGVIPGIVGAVVVAVAGAISSF :: :: : :.::: :: .:: ::. : : ::.: :...:...:. ::.::. NP_113 SDKDLEDIVGGGEYKPDKGKGDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSY 150 160 170 180 190 200 150 160 170 180 pF1KB8 IAYQKKKLCFKENAEQG-EVDMESHRNANA----EPAVQRTLLEK :.::.::.:: . .:: ..:. . .: .: :: :. . : NP_113 ISYQQKKFCF--SIQQGLNADYVKGENLEAVVCEEPQVKYSTLHTQSAEPPPPPEPARI 210 220 230 240 250 260 >>XP_016885380 (OMIM: 300846) PREDICTED: CD99 antigen-li (218 aa) initn: 191 init1: 145 opt: 255 Z-score: 202.3 bits: 44.3 E(85289): 0.00016 Smith-Waterman score: 273; 37.7% identity (61.2% similar) in 183 aa overlap (3-163:5-175) 10 20 30 40 pF1KB8 MARGAALALLLFGLLGVLVAAPDGGFD---LSDALPDNENKKP-----TAIPKKP--- :.: :. : :.: ..:: .: :: : ::. .. . : :. :.: XP_016 MVAWRSAFLVCLAFSL-ATLVQRGSGDFDDFNLEDAVKETSSVKQRWNHVTTTTKRPVTT 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 -----SAGDDFDLGDAVVDGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGG . :.::::.::. : .:: : . ::. ...:.::: :: : :.:: XP_016 RAPANTLGNDFDLADAL-DDRND--RDDGRRKPI--------AGGGGFSDKDLEDIVGGG 60 70 80 90 100 110 120 130 140 150 pF1KB8 E---GKGGSDGG-GSHRKEGEEADA-PGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFK- : :: .:: ::. : : ::.: :...:...:. ::.::.:.::.::.::. XP_016 EYKPDKGKGDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSI 110 120 130 140 150 160 160 170 180 pF1KB8 ENAEQGEVDMESHRNANAEPAVQRTLLEK ..: :. XP_016 QHAAAGQGNAALPSSLSFCFSLDASSFAPCSGASLPLFSLLLPWHSPTWL 170 180 190 200 210 >>NP_001229543 (OMIM: 300846) CD99 antigen-like protein (272 aa) initn: 231 init1: 145 opt: 254 Z-score: 200.3 bits: 44.3 E(85289): 0.0002 Smith-Waterman score: 274; 35.8% identity (58.3% similar) in 204 aa overlap (20-183:64-256) 10 20 30 40 pF1KB8 MARGAALALLLFGLLGVLVAAPDG-----GFDLSDALPDNEN--KKP-- : : : :.::.::: :... .:: NP_001 DAVKETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGPTEGSGLDLADALDDQDDGRRKPGI 40 50 60 70 80 90 50 60 70 80 pF1KB8 ---------TAIPKKP--------SAGDDFDLGDAVVDGENDDPRPPNPPKPMPNPNPNH :. :.: . :.::::.::. : .:: : . ::. NP_001 GGRERWNHVTTTTKRPVTTRAPANTLGNDFDLADAL-DDRND--RDDGRRKPI------- 100 110 120 130 140 90 100 110 120 130 pF1KB8 PSSSGSFSDADLADGVSGGE---GKGGSDGG-GSHRKEGEEADA-PGVIPGIVGAVVVAV ...:.::: :: : :.::: :: .:: ::. : : ::.: :...:...:. NP_001 -AGGGGFSDKDLEDIVGGGEYKPDKGKGDGRYGSNDDPGSGMVAEPGTIAGVASALAMAL 150 160 170 180 190 200 140 150 160 170 180 pF1KB8 AGAISSFIAYQKKKLCFK-ENAEQGE----VDMESHRNANA----EPAVQRTLLEK ::.::.:.::.::.::. ..: :. .:. . .: .: :: :. . : NP_001 IGAVSSYISYQQKKFCFSIQHAAAGQEGLNADYVKGENLEAVVCEEPQVKYSTLHTQSAE 210 220 230 240 250 260 NP_001 PPPPPEPARI 270 185 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:45:00 2016 done: Fri Nov 4 10:45:01 2016 Total Scan time: 5.620 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]